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Coherent Raman Scattering Microscopy [Kõva köide]

Edited by (Harvard University, Cambridge, Massachusetts, USA), Edited by (Purdue University, West Lafayette, Indiana, USA)
  • Formaat: Hardback, 610 pages, kõrgus x laius: 254x178 mm, kaal: 1451 g, 12 Tables, black and white; 284 Illustrations, color; 284 Illustrations, black and white
  • Sari: Series in Cellular and Clinical Imaging
  • Ilmumisaeg: 29-Oct-2012
  • Kirjastus: CRC Press Inc
  • ISBN-10: 1439867658
  • ISBN-13: 9781439867655
  • Formaat: Hardback, 610 pages, kõrgus x laius: 254x178 mm, kaal: 1451 g, 12 Tables, black and white; 284 Illustrations, color; 284 Illustrations, black and white
  • Sari: Series in Cellular and Clinical Imaging
  • Ilmumisaeg: 29-Oct-2012
  • Kirjastus: CRC Press Inc
  • ISBN-10: 1439867658
  • ISBN-13: 9781439867655
The First Book on CRS Microscopy

Compared to conventional Raman microscopy, coherent Raman scattering (CRS) allows label-free imaging of living cells and tissues at video rate by enhancing the weak Raman signal through nonlinear excitation. Edited by pioneers in the field and with contributions from a distinguished team of experts, Coherent Raman Scattering Microscopy explains how CRS can be used to obtain a point-by-point chemical map of live cells and tissues.

In color throughout, the book starts by establishing the foundation of CRS microscopy. It discusses the principles of nonlinear optical spectroscopy, particularly coherent Raman spectroscopy, and presents the theories of contrast mechanisms pertinent to CRS microscopy. The text then provides important technical aspects of CRS microscopy, including microscope construction, detection schemes, and data analyses. It concludes with a survey of applications that demonstrate how CRS microscopy has become a valuable tool in biomedicine.

Due to its label-free, noninvasive examinations of living cells and organisms, CRS microscopy has opened up exciting prospects in biology and medicinefrom the mapping of 3D distributions of small drug molecules to identifying tumors in tissues. An in-depth exploration of the theories, technology, and applications, this book shows how CRS microscopy has impacted human health and will deepen our understanding of life processes in the future.

Arvustused

"This book makes a seminal contribution to the field of biomedical imaging, and provides the reader with an excellent introduction and in-depth descriptions of the latest and greatest implementations of coherent Raman imaging technologyenough to jump start a new program or infuse new life into an existing one. The clear descriptions of a wide range of applications show how the methods are being used at present and indicate many different and varied future paths. This book is an excellent addition to the bookshelves of biomedical imaging practitioners and researchers in related fields, including surface analysis, process control, forensics, and others." David S. Moore, Los Alamos National Laboratory, Analytical and Bioanalytical Chemistry, 2013

"Interested readers can find an excellent mix of [ optical platforms and applications given a solid theoretical approach] in this book, which is the first one dealing in a comprehensive and exhaustive way with CRS microscopy and related techniques. No one involved in optical microscopy and spectroscopy should miss this text, which is able to offer new exciting scenarios and, for sure, at least one new idea after reading." Alberto Diaspro, Italian Institute of Technology (IIT), Journal of Biomedical Optics, 2014

Series Preface ix
Preface xi
Editors xv
Contributors xvii
Part I Theory
1 Theory of Coherent Raman Scattering
3(40)
Eric Olaf Potma
Shaul Mukamel
2 Coherent Raman Scattering under Tightly Focused Conditions
43(36)
Eric Olaf Potma
Xiaoliang Sunney Xie
Andreas Volkmer
Ji-Xin Cheng
Part II Platforms
3 Construction of a Coherent Raman Microscope
79(20)
Brian G. Saar
Xiaoliang Sunney Xie
4 Stimulated Raman Scattering Microscopy
99(22)
Christian Freudiger
Xiaoliang Sunney Xie
5 Femtosecond versus Picosecond Pulses for Coherent Raman Microscopy
121(16)
Mikhail N. Slipchenko
Delong Zhang
Ji-Xin Cheng
6 Miniature Coherent Raman Probes for In Vivo Biomedical Imaging
137(24)
Gangjun Liu
Mihaela Balu
Zhongping Chen
Eric Olaf Potma
7 Wide-Field CARS-Microscopy
161(28)
Alexander Jesacher
Gregor Thalhammer
Stefan Bernet
Monika Ritsch-Marte
8 Vibrational Spectromicroscopy by Coupling Coherent Raman Imaging with Spontaneous Raman Spectral Analysis
189(18)
Mikhail N. Slipchenko
Ji-Xin Cheng
9 Coherent Control in CARS
207(30)
Jonathan M. Levitt
Ori Katz
Yaron Silberberg
10 Fourier Transform CARS Microscopy
237(16)
Jennifer P. Ogilvie
11 CRS with Alternative Beam Profiles
253(24)
Varun Raghunathan
Hyunmin Kim
Stephan Stranick
Eric Olaf Potma
12 Vibrational Phase Microscopy
277(14)
Martin Jurna
Cees Otto
Herman L. Offerhaus
13 Multiplex CARS Microscopy
291(18)
James P.R. Day
Katrin F. Domke
Gianluca Rago
Erik M. Vartiainen
Mischa Bonn
14 Interferometric Multiplex CARS
309(20)
Sang-Hyun Lim
15 Photonic Crystal Fiber-Based Broadband CARS Microscopy
329(24)
Marcus T. Cicerone
Young Jong Lee
Sapun H. Parekh
Khaled A. Aamer
16 Multiplex Stimulated Raman Scattering Microscopy
353(36)
Dan Fu
Xiaoliang Sunney Xie
Part III Applications
17 Imaging Myelin Sheath Ex Vivo and In Vivo by CARS Microscopy
389(16)
Yan Fu
Yunzhou (Sophia) Shi
Ji-Xin Cheng
18 Imaging Lipid Metabolism in Caenorhabditis elegans and Other Model Organisms
405(16)
Helen Fink
Christian Brackmann
Annika Enejder
19 Lipid-Droplet Biology and Obesity-Related Health Risks
421(18)
Thuc T. Le
20 White Matter Injury: Cellular-Level Myelin Damage Quantification in Live Animals
439(18)
Erik Belanger
F.P. Henry
R. Vallee
M.A. Randolph
I.E. Kochevar
J.M. Winograd
Charles P. Lin
Daniel Cote
21 CARS Microscopy Study of Liquid Crystals
457(22)
Heung-Shik Park
Oleg D. Lavrentovich
22 Live Cell Imaging by Multiplex CARS Microspectroscopy
479(26)
Hideaki Kano
23 Coherent Raman Scattering Imaging of Drug Delivery Systems
505(14)
Ling Tong
Ji-Xin Cheng
24 Applications of Stimulated Raman Scattering Microscopy
519(18)
Christian Freudiger
Daniel A. Orringer
Xiaoliang Sunney Xie
25 Applications of Coherent Anti-Stokes Raman Spectroscopy Imaging to Cardiovascular Diseases
537(10)
Han-Wei Wang
Michael Sturek
Ji-Xin Cheng
26 Applications of CARS Microscopy to Tissue Engineering
547(22)
Annika Enejder
Christian Brackmann
27 Dietary Fat Absorption Visualized by CARS Microscopy
569(12)
Kimberly K. Buhman
Index 581
Ji-Xin Cheng is a professor of biomedical engineering at Purdue University. He earned a PhD from the University of Science and Technology of China and completed postdoctoral research at the Hong Kong University of Science and Technology and Harvard University. He is a pioneer in the development and biomedical application of molecular vibration-based imaging tools.

Xiaoliang Sunney Xie is a Mallinckrodt Professor of Chemistry at Harvard University. He earned a PhD from the University of California-San Diego and completed postdoctoral research at the University of Chicago. He is well-known for his innovations in nonlinear Raman microscopy and his pioneering work in single-molecule biophysical chemistry, including enzyme dynamics and live cell gene expression.