| List Of Contributors |
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xi | |
| Preface To The Second Edition |
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xv | |
| Acknowledgments From The First Edition |
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xvii | |
| Chapter 1 Introduction |
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Overview And Introduction To The Second Edition |
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1 | (8) |
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Comparative Pathology: Closing a Gap |
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1 | (4) |
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C57BL/6 Mice as Index Strain |
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5 | (1) |
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Sprague-Dawley Rats as Index Strain |
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5 | (1) |
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5 | (1) |
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Further Reading and Relevant Websites |
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6 | (3) |
| Chapter 2 Phenotyping |
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9 | (1) |
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10 | (6) |
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Strategies 10, Materials and Methods |
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10 | (6) |
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16 | (4) |
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20 | (1) |
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Further Reading and Relevant Websites |
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20 | (3) |
| Chapter 3 Necropsy And Histology |
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23 | (1) |
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Fixation Considerations Prior to Necropsy |
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24 | (3) |
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Major Groups of Fixatives |
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24 | (1) |
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Tissue Fixation Variables to Consider |
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25 | (1) |
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Decalcification of Bone Samples |
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26 | (1) |
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Frozen Tissue for Histologic Evaluation |
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27 | (1) |
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27 | (18) |
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28 | (1) |
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29 | (1) |
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30 | (2) |
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32 | (13) |
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45 | (1) |
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45 | (6) |
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47 | (2) |
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49 | (1) |
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49 | (1) |
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49 | (2) |
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Further Reading and Relevant Websites |
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51 | (2) |
| Chapter 4 Microscopy, Immunohistochemistry, Digital Imaging, And Quantitative Microscopy |
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53 | (1) |
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Key Elements of Microscopy |
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53 | (3) |
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53 | (1) |
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54 | (1) |
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54 | (2) |
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56 | (5) |
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56 | (1) |
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56 | (1) |
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Validation of Antibody Specificity |
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56 | (2) |
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58 | (2) |
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60 | (1) |
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60 | (1) |
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Key Elements of Digital Imaging |
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61 | (1) |
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Key Elements of Quantitative Microscopy |
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62 | (2) |
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62 | (1) |
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63 | (1) |
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64 | (1) |
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IHC and Imaging Reproducibility |
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64 | (1) |
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65 | (1) |
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65 | (2) |
| Chapter 5 Skeletal System |
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67 | (1) |
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68 | (5) |
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68 | (1) |
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69 | (4) |
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73 | (9) |
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73 | (2) |
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75 | (7) |
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82 | (1) |
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82 | (1) |
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83 | (1) |
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83 | (2) |
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83 | (1) |
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83 | (2) |
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85 | (2) |
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87 | (2) |
| Chapter 6 Nose, Sinus, Pharynx, And Larynx |
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89 | (1) |
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90 | (15) |
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90 | (2) |
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Preparation of Nasal Tissues for Microscopic Exam |
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92 | (2) |
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94 | (9) |
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Other Nasal Cavity Features |
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103 | (2) |
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105 | (7) |
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105 | (1) |
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Preparation of Rodent Pharynx and Larynx for Microscopic Exam |
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106 | (1) |
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106 | (6) |
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112 | (3) |
| Chapter 7 Oral Cavity And Teeth |
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115 | (1) |
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115 | (6) |
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115 | (2) |
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117 | (4) |
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121 | (12) |
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121 | (4) |
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125 | (8) |
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133 | (2) |
| Chapter 8 Salivary Glands |
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135 | (1) |
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135 | (4) |
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135 | (1) |
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135 | (4) |
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139 | (3) |
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139 | (3) |
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142 | (1) |
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142 | (1) |
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142 | (1) |
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142 | (1) |
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143 | (1) |
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143 | (1) |
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144 | (1) |
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144 | (3) |
| Chapter 9 Respiratory System |
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147 | (1) |
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147 | (4) |
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147 | (1) |
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148 | (3) |
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151 | (1) |
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151 | (1) |
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Bronchi to Terminal Bronchioles |
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151 | (5) |
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151 | (1) |
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152 | (4) |
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156 | (3) |
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156 | (1) |
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156 | (3) |
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159 | (1) |
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159 | (1) |
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159 | (1) |
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159 | (3) |
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159 | (1) |
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160 | (2) |
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162 | (1) |
| Chapter 10 Cardiovascular |
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163 | (4) |
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167 | (11) |
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167 | (3) |
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Relative Size Considerations |
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170 | (2) |
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172 | (6) |
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178 | (3) |
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178 | (1) |
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178 | (3) |
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181 | (1) |
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Great Vessels and Coronary Vasculature |
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181 | (6) |
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181 | (3) |
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184 | (3) |
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Common Incidental Findings in Rodents |
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187 | (1) |
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188 | (3) |
| Chapter 11 Upper Gastrointestinal Tract |
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191 | (1) |
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191 | (3) |
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191 | (1) |
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192 | (2) |
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194 | (7) |
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194 | (1) |
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195 | (6) |
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201 | (10) |
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201 | (1) |
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202 | (9) |
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211 | (1) |
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211 | (2) |
| Chapter 12 Lower Gastrointestinal Tract |
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213 | (1) |
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213 | (3) |
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213 | (3) |
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216 | (1) |
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216 | (4) |
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216 | (2) |
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218 | (2) |
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220 | (8) |
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220 | (3) |
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223 | (5) |
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Gut-Associated Lymphoid Tissue |
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228 | (1) |
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228 | (1) |
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228 | (1) |
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228 | (1) |
| Chapter 13 Hepatobiliary System |
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229 | (1) |
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230 | (8) |
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230 | (3) |
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233 | (5) |
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238 | (1) |
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239 | (2) |
| Chapter 14 Pancreas |
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241 | (1) |
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241 | (8) |
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241 | (2) |
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243 | (6) |
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249 | (2) |
| Chapter 15 Endocrine System |
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Krista Marie DuBray La Perle |
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251 | (1) |
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251 | (4) |
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251 | (2) |
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253 | (2) |
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255 | (1) |
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255 | (1) |
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256 | (1) |
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256 | (6) |
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256 | (2) |
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258 | (4) |
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262 | (6) |
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262 | (1) |
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262 | (6) |
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268 | (2) |
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268 | (1) |
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269 | (1) |
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270 | (2) |
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270 | (1) |
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271 | (1) |
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272 | (3) |
| Chapter 16 Urinary System |
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275 | (1) |
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275 | (16) |
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275 | (7) |
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282 | (9) |
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Ureters, Urinary Bladder, and Urethra |
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291 | (10) |
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291 | (5) |
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296 | (5) |
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301 | (2) |
| Chapter 17 Female Reproductive System |
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Katherine N. Gibson-Corley |
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303 | (1) |
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303 | (7) |
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303 | (4) |
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307 | (3) |
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310 | (5) |
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310 | (2) |
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312 | (3) |
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315 | (5) |
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315 | (1) |
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315 | (5) |
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320 | (1) |
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320 | (1) |
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321 | (1) |
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321 | (13) |
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321 | (3) |
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324 | (10) |
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334 | (1) |
| Chapter 18 Male Reproductive System |
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335 | (1) |
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336 | (5) |
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336 | (2) |
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338 | (3) |
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341 | (1) |
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341 | (1) |
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342 | (1) |
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342 | (1) |
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342 | (1) |
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343 | (1) |
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343 | (3) |
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343 | (2) |
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345 | (1) |
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Seminal Vesicles (Vesicular Glands) |
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346 | (2) |
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346 | (1) |
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346 | (2) |
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348 | (6) |
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348 | (1) |
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349 | (5) |
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354 | (1) |
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354 | (1) |
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354 | (1) |
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355 | (1) |
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355 | (1) |
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355 | (1) |
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355 | (2) |
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355 | (1) |
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355 | (2) |
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357 | (3) |
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357 | (3) |
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360 | (1) |
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360 | (2) |
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360 | (1) |
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360 | (2) |
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362 | (3) |
| Chapter 19 Hematopoietic And Lymphoid Tissue |
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365 | (1) |
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365 | (5) |
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366 | (3) |
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369 | (1) |
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370 | (5) |
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371 | (1) |
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372 | (3) |
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375 | (6) |
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376 | (1) |
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376 | (5) |
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381 | (9) |
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381 | (4) |
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385 | (5) |
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390 | (7) |
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391 | (1) |
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391 | (6) |
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Mucosa-Associated Lymphoid Tissue |
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397 | (3) |
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400 | (1) |
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400 | (1) |
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400 | (3) |
| Chapter 20 Nervous System |
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403 | (2) |
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405 | (28) |
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405 | (19) |
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424 | (8) |
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432 | (1) |
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433 | (2) |
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433 | (1) |
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434 | (1) |
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435 | (5) |
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435 | (4) |
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439 | (1) |
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440 | (3) |
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Conventions for Neuroanatomic Terminology |
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440 | (1) |
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Special Methods in Neurohistologic Preparation |
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441 | (2) |
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443 | (1) |
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Further Reading and Relevant Websites |
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443 | (2) |
| Chapter 21 Special Senses: Eye |
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445 | (1) |
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445 | (1) |
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445 | (1) |
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446 | (2) |
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446 | (1) |
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446 | (2) |
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448 | (7) |
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448 | (3) |
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451 | (4) |
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455 | (5) |
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455 | (1) |
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456 | (4) |
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Vitreous Chamber and Lens |
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460 | (1) |
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460 | (1) |
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460 | (1) |
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461 | (2) |
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461 | (2) |
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463 | (1) |
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463 | (1) |
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463 | (1) |
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463 | (1) |
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463 | (1) |
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463 | (1) |
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464 | (1) |
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464 | (3) |
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464 | (1) |
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464 | (3) |
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Lacrimal Gland and Drainage System |
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467 | (1) |
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467 | (1) |
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467 | (1) |
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467 | (3) |
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470 | (1) |
| Chapter 22 Special Senses: Ear |
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471 | (1) |
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471 | (2) |
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471 | (1) |
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471 | (2) |
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473 | (6) |
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473 | (5) |
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478 | (1) |
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479 | (6) |
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479 | (1) |
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479 | (6) |
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485 | (2) |
| Chapter 23 Mammary Gland |
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487 | (1) |
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487 | (12) |
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487 | (3) |
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Subgross Anatomy and Histology |
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490 | (9) |
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Mammary Gland Natural History and Reproductive Cycles |
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499 | (9) |
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499 | (3) |
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Ovarian (Estrous and Menstrual) Cycle |
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502 | (1) |
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502 | (1) |
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503 | (3) |
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506 | (2) |
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508 | (3) |
| Chapter 24 Skin And Adnexa |
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511 | (1) |
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512 | (11) |
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513 | (10) |
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523 | (17) |
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523 | (17) |
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540 | (3) |
| Index |
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543 | |