This handbook is an essential guide to overcoming the challenges posed by Vitiligo by providing a tailored solution. Vitiligo is a complex range of pigmentation disorders impacting millions worldwide. The book enables healthcare professionals to efficiently deliver precise, evidence-based care for Vitiligo, drawing from the most recent research and clinical insights in an accessible format.
Divided into five sections covering basic science to surgical therapy for the condition, Section I unveils the fundamentals from the genesis of melanocytes to the complex web of genetics and epidemiology. It also navigates the pathogenesis and histopathology, unveiling the mechanics of repigmentation. Meanwhile, Section II delves into clinical intricacies, interpreting classifications, clinical features, and the natural course of Vitiligo. Section III explains cutting-edge medical therapies, from topical approaches to innovative biological interventions. The surgical odyssey in Section IV provides insights into patient selection, grafting methods, and associated complications. The book also covers some special topics in Section V, ranging from depigmentation strategies to childhood vitiligo.
The book is relevant for dermatologists, researchers, healthcare professionals, and postgraduate and medical students interested in Vitiligo and its management.
Part 1 Basic Science.- 1 Introduction.- 2 Melanocyte Biology and
Melanogenesis.- 3 Genetics and Epidemiology of Vitiligo- 4 Pathogenesis,
Histopathology of Vitiligo.- 5 Mechanism of Repigmentation in Vitiligo.- Part
2 Clinical Science.- 6 Classification, Clinical Features, Associations,
Special Variants.- 7 Natural History and Prognosis.- 8 Dermoscopy and
Non-Invasive Methods of Evaluation.- 9 Stability, Quality of Life and Outcome
Measures.- 10 Psychological Burden and Ancillary Support.- Part 3 Medical
Therapy.- 11 Topical Therapies.- 12 Systemic Immunomodulatory and
Immunosuppressive Therapies.- 13 Small Molecule and Biologic Therapies.- 14
Laser and Other Light-Based Therapies.- 15 Complications of Medical
Modalities of Therapy.- Part 4 Surgical Therapy.- 16 Patient Selection
andEvaluation.- 17 Tissue Grafting Methods.- 18 Cellular Grafting Methods.-
19 Non-Grafting Methods (Dermabrasion, Excision, Therapeutic Wounding,
Cryotherapy).- 20 Complications of Surgical Modalities.- Part 5 Special
Topics.- 21 Depigmentation Therapies.- 22 Camouflage in Vitiligo.- 23
Late-onset and Childhood Vitiligo.- 24 Animal and In-Virto Models.- 25
Further Directions in Vitiligo.
Dr. Rashmi Sarkar is working as the director professor in the Department of Dermatology and Venereology at Lady Hardinge Medical College and Associated SSK and KSC Hospitals, New Delhi, India, affiliated with Delhi University. Previously, Dr. Sarkar has also worked as a professor at Maulana Azad Medical College, New Delhi, and assistant professor,Government Medical College, Chandigarh, India, and served as an examiner for MD, Diploma, and PhD in Dermatology and DNB. With an H Index of 45 and a research gate score 39.0, Dr. Sarkar has published over 260 papers in peer-reviewed national and international journals, over 120 chapters in various books, and edited 24 books. She is a global leader in pigmentary disorders.
Dr. Vignesh Narayan R has completed his fellowship in Dermatologic Surgery at Bangalore Medical College and Research Institute, Bangalore, India. His areas of interest include pigmentary disorders and dermatologic surgery. He has published many papers in peer-reviewed national and international journals. Dr. Narayan had served as the editor-in-chief of the Residream Magazine of the Indian Association of Dermatologists, Venereologists, and Leprologists (IADVL) National residents committee and the IADVL YUVA Cell.
