This work addresses a variety of topics that are of interest in their own right and because they bear on the evaluation of the safety of fluoridation. The latter is important because the demonstration of "no effect" from the use of fluorides is very difficult and the available data need to be periodically reexamined to reduce the theoretical amount
Foreword -- Introduction -- Historical Perspectives -- Fluoride Supplements for Systemic Effects in Caries Prevention -- Topical Fluorides in the Prevention and Arrest of Dental Caries -- Fluoride in the Treatment of Osteoporosis -- Inorganic and Organic Fluorine in Human Blood -- Is Fluoride Intake in the United States Changing? -- Distribution of Fluroide Among Body Compartments -- The Effect of Body Fluid pH on Fluoride Distribution, Toxicity, and Renal Clearance -- Fluoride Resistance in Cell Cultures -- Fluoride from Anesthetics and Its Consequences -- The Safety of Fluoride Tablets or Drops -- Fluoridation and Bone Disease in Renal Patients -- Claims of Harm from Fluoridation