Stroke is the leading cause of neurological morbidity and mortality and the third leading cause of mortality worldwide. In spite of several advances over the past two decades in acute stroke management, stroke prevention and neuroprotection, there is no clear consensus in any of the areas of diagnosis and management. The complex interplay between treatment modalities and the individual patient makes each case quite unique and physicians need to walk the tightrope of balancing the subtle and complicated see-saw of evidence and experience-based medicine. This book has contributions by a group of internationally recognized experts who have written extensively on strategies of 'thinking out of the box while not discarding the current evidence'. The authors have taken their expertise and experience into account while formulating the best practice recommendations fully recognizing that guidelines fall short and there is a continued need to synthesize current best practice opinion with individualized medicine. This book offers a rational approach to the current diagnosis and treatment of stroke that individual physicians can apply to their practice.
Arvustused
"'Controversies in Stroke Care elegantly describes the issues behind the most compelling unresolved questions facing the stroke community.... [ It] essentially provides a roadmap to inform the priorities for research in the next decade.' (Karen L. Furie. Neurologist-in-Chief, Rhode Island Hospital, Professor and Chair of Neurology, Alpert School of Medicine at Brown University, USA)"
Foreword |
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vii | |
Preface |
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viii | |
Acknowledgements |
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ix | |
Contributors |
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x | |
Abbreviations |
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xiii | |
1 Personalized Medicine-What Is It? Is It Worthwhile? Can It Be Continued In An Era Dominated By Managed Care And 'Evidence-Based Medicine'? |
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1 | (12) |
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2 Imaging The Ischaemic Penumbra: Ready For Prime Time In Clinical Trials And Practice |
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13 | (11) |
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3 Neuroprotection In Ischaemic Stroke |
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24 | (18) |
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4 Thrornbolysis For Acute Ischaemic Stroke...Are Off-Label Indications Justified? |
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42 | (13) |
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5 Antihypertensive Medications In Stroke: Controversies And Recommendations |
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55 | (22) |
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6 Intra-Arterial Interventions Within The 3-Hour Window After Acute Ischaemic Stroke |
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77 | (8) |
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7 Controversies In The Management Of Intracerebral Haemorrhage |
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85 | (10) |
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8 Do All Stroke Patients Need To Be Evaluated For CAD? |
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95 | (11) |
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9 Acute High-Dose Statins Improve Stroke Outcome: Myth Or Reality? |
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106 | (9) |
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10 Cervicocerebral Arterial Dissections |
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115 | (11) |
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11 Prevention Of Deep Vein Thrombosis In Patients With Acute Stroke |
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126 | (9) |
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12 Antiepileptic Drug Prophylaxis For Seizures In Cerebrovascular Accidents |
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135 | (5) |
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13 Antiplatelet Drugs: Does It Make A Difference Which One You Use? |
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140 | (18) |
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14 Cerebral Venous Thrombosis |
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158 | (12) |
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15 Non-Convulsive Status And EEG Monitoring In The Neuro-ICU |
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170 | (7) |
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16 Evaluation For Hypercoagulable States: Special Reference To Venous And Arterial Thrombosis |
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177 | (15) |
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17 Role Of Infections In Stroke: How True Is The Association? |
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192 | (15) |
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V.C.S. Srinivasarao Bandaru |
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18 Relationship Between Migraine And Stroke: How True And How Close? |
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207 | (7) |
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19 Prevention Of Ischaemic Stroke: Carotid Revascularization |
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214 | (10) |
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20 Are Alzheimer Dementia (AD) And Vascular Dementia (VAD), Different Clinical Profiles Of The Same Disease Spectrum?: Defining The Common Markers |
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224 | (10) |
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21 Restorative Therapy In Stroke: Is There A Role For Stem Cells? |
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234 | (25) |
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22 Controversies In Telemedicine |
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259 | (14) |
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23 Stroke In The Young: Does The Aetiology And Prognosis Differ From Stroke In Older Patients? |
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273 | (43) |
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24 Obstructive Sleep Apnoea And Stroke |
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316 | (7) |
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Index |
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323 | |
Majaz Moonis MRCP, MD (Medicine), DM (Neurology), FRCP (Edin.) MRCP(I), FAAN, FAHA is Professor of Neurology at the University of Massachusetts Medical School and the Director of the Stroke Program and Services including the Vascular Neurology Fellowship Program, Massachusetts, USA. M.V. Padma Srivastava MD, DM (Neurology), FAMS is Professor of Neurology at the All India Institute of Medical Sciences, New Delhi, India.