Curcumin-based Nanomedicines as Cancer Therapeutics presents a consistent and thorough overview of nanocurcumin applications in cancer treatments. It brings together the novel applications of nanocurcumin in biological milieu as well as helps readers to define the major gaps in knowledge that can lead to significant scientific discoveries.
Nanocurcumin has been widely explored for the treatment of various cancers; however, the scientific literature is inconsistent in style and structure and scattered across many sources. By providing an explicit account on vital aspects on nanocurcumin-based anticancer delivery approaches and discussing the perspectives of the technologies explored so far based upon the findings outlined, the book offers updated and in-depth knowledge on the topic in one single source written by global leading experts.
In addition, the book aims to stimulate the interest of the academic researchers, industrial scientists, businessmen, and young scholars to address key multidisciplinary challenges faced by nanotechnologists to foster the desired collaboration among biologists, chemists, physicists, engineers, and clinicians to find proper and efficient new cancer treatments.
Part-A: Curcumin: Introduction, structure, and physicochemical attributes
1. Historical background, pharmacological effect, and potential therapeutic effect of turmeric and its major compound curcumin
2. Curcumin as pharmaceutical leader
3. Chemical structure and molecular targets of curcumin for cancer therapy
Part-B: Smart drug delivery approaches for curcumin delivery in cancer therapy
4. Curcumin-drug conjugate-based drug delivery as cancer therapeutics
5. Curcumin-cyclodextrin based drug delivery as cancer therapeutics
6. Curcumin-solid dispersion-based drug delivery as cancer therapeutics
7. Curcumin-microcapsule based drug delivery as cancer therapeutics
Part-C: Nanotechnology mediated curcumin delivery in cancer therapy
8. Nanoemulsion based curcumin delivery as cancer therapeutics
9. Micelles based curcumin delivery as cancer therapeutics
10. Liposomes based curcumin delivery as cancer therapeutics
11. Nanospheres based curcumin delivery as cancer therapeutics
12. Inorganic nanoparticles-based curcumin delivery as cancer therapeutics
13. Organic nanoparticles-based curcumin delivery as cancer therapeutics
14. PLGA nanoparticle-based curcumin delivery as cancer therapeutics
15. Dendrimer based curcumin delivery as cancer therapeutics
16. Carbon nanotube-based curcumin delivery as cancer therapeutics
17. Nanogels, nanodisks, yeast cells, and metallo-complexes based curcumin delivery for therapeutic applications
Part-D: Recent advances in nanocurcumin delivery in cancer therapy
18. Nanohybrid drug delivery approach as novel opportunity for curcumin delivery as cancer therapeutics
19. Curcumin based combination anticancer drug delivery systems
20. Codelivery of curcumin and siRNA as anticancer therapeutics
Part-E: Challenges and future perspectives of nano-curcumin drug delivery
21. Challenges associated with nano-curcumin anticancer drug delivery systems
22. Clinical Trials, patents, and marketed products of nano-curcumin anticancer drug delivery systems
23. Concluding remarks and future perspective of nano-curcumin anticancer drug delivery systems
Dr. Amirhossein Sahebkar received his PharmD and PhD (in Medical Biotechnology) degrees from the Mashhad University of Medical Sciences (MUMS; Mashhad, Iran). His research focuses on the investigation of novel natural products for the management of severe cardiometabolic disorders. He has conducted numerous research projects dealing with basic, experimental, and clinical research on curcuminoids. Dr. Prashant Kesharwani is assistant professor of Pharmaceutics at Department of Pharmaceutical Sciences, Dr. Harisingh Gour Vishwavidyalaya, Sagar, Madhya Pradesh, India. He has more than 12 years of teaching, research, and industrial experience at international levels from various countries, including the United States, Malaysia, and India. An overarching goal of his current research is the development of nanoengineered drug delivery systems for various diseases. He has more than 350 international publications in well-reputed journals and more than 25 international books (Elsevier). He is a recipient of many research grants from various funding bodies. He is also the recipient of several internationally acclaimed awards, such as USERN Laureate award”, most prestigious SERB-Ramanujan Fellowship Award”. He actively participates in outreach and scientific dissemination for the service of the wider community. His Number of citations is = 26779; h-index = 85; i-10 index = 370 (According to google scholar on March 2025). He has more than 30 international publications published in very high impact factor journals (Progress in Polymer Sciences IF 32.063, Molecular Sciences IF 41.444, Progress in Material Sciences IF 48.580, Advanced Materials IF 29.4, Drug Resistance Update IF 22.841 and Material Todays IF 32.072). He has presented many invited talks and oral presentations at prestigious scientific peer-conferences, received international acclaims and awards for research contribution, supervised students/junior researchers and actively participated in outreach and scientific dissemination for the service of the wider community.
