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Dangerous Medicine: The Story behind Human Experiments with Hepatitis [Kõva köide]

  • Formaat: Hardback, 304 pages, kõrgus x laius x paksus: 235x156x27 mm, 16 b-w illus.
  • Ilmumisaeg: 08-Feb-2022
  • Kirjastus: Yale University Press
  • ISBN-10: 030025962X
  • ISBN-13: 9780300259629
  • Formaat: Hardback, 304 pages, kõrgus x laius x paksus: 235x156x27 mm, 16 b-w illus.
  • Ilmumisaeg: 08-Feb-2022
  • Kirjastus: Yale University Press
  • ISBN-10: 030025962X
  • ISBN-13: 9780300259629
The untold history of America’s mid-twentieth-century program of hepatitis infection research, its scientists’ aspirations, and the damage the project caused human subjects
 
“Sydney Halpern has written a compelling, if unsettling, history of hepatitis research during World War II and the Cold War. It will become a must-read for anyone interested in bioethics and medical history.”—Susan E. Lederer, author of Subjected to Science and Flesh and Blood
 
From 1942 through 1972, American biomedical researchers deliberately infected people with hepatitis. Government-sponsored researchers were attempting to discover the basic features of the disease and the viruses causing it, and to develop interventions that would quell recurring outbreaks. Drawing from extensive archival research and in-person interviews, Sydney Halpern traces the hepatitis program from its origins in World War II through its expansion during the initial Cold War years, to its demise in the early 1970s amid an outcry over research abuse.
 
The subjects in hepatitis studies were members of stigmatized groups—conscientious objectors, prison inmates, the mentally ill, and developmentally disabled adults and children. The book reveals how researchers invoked military and scientific imperatives and the rhetoric of a common good to win support for the experiments and access to recruits. Halpern examines the participants’ long-term health consequences and raises troubling questions about hazardous human experiments aimed at controlling today’s epidemic diseases.

The untold history of America’s mid-twentieth-century program of hepatitis infection research, its scientists’ aspirations, and the damage the project caused human subjects

Arvustused

Halperns story is chilling, told with clarity and commendable brevity and, most importantly, is of crucial relevance today. The emergence of Covid-19 galvanised calls for the creation of experiments in which volunteers would be infected with SARS-CoV-2 to help understand how the disease spreads and behaves. Some of these studies continue.Robin McKie, The Observer

Winner of the 2024 George Rosen Prize from the American Association for the History of Medicine

Sydney Halpern has written a compelling, if unsettling, history of hepatitis research during World War II and the Cold War. It will become a must-read for anyone interested in bioethics and medical history.Susan E. Lederer, author of Subjected to Science and Flesh and Blood

An immensely important account of decades of human experiments that raised serious moral questions, not only in hindsight as is often claimed, but also at the time they were conducted.Jonathan D. Moreno, coauthor of Everybody Wants to Go to Heaven but Nobody Wants to Die: Bioethics and the Transformation of Healthcare in America

Sydney Halperns Dangerous Medicine, a scandal-strewn history of hepatitis research, provides a frighteningly timely reminder of the dangers vulnerable patients face when medical research attacks disease in time of war.Paul A. Lombardo, author of Three Generations, No Imbeciles: Eugenics, the Supreme Court, and Buck v. Bell

Preface vii
Acknowledgments xi
List of Abbreviations
xiii
Introduction: A Sobering Story 1(16)
1942-1946
1 In the National Interest
17(20)
2 Logistics on the Medical Battlefront
37(22)
3 Guinea Pig Camp
59(24)
1946-1954
4 Nuremberg Notwithstanding
83(18)
5 Tales of Redemption
101(16)
6 Cold War Calculations
117(24)
1956-1972 And Beyond
7 Science on the Cusp
141(19)
8 Backlash
160(21)
9 An Ending without Closure
181(8)
Epilogue: Misgivings of Hindsight 189(6)
Glossary 195(4)
Record Group Abbreviations 199(6)
Notes 205(70)
Index 275
Sydney A. Halpern is professor emerita at University of Illinois at Chicago, and lecturer in the Program in Medical Humanities and Bioethics, Feinberg School of Medicine, Northwestern University.