Drug Delivery and Biomedical Applications of Porous Silicon-Based Nanocarriers delivers an up-to-date and complete overview of the range of biomedical applications for porous silicon nanomaterials, with a special emphasis on drug delivery. This book introduces the fundamentals and beneficial properties of porous silicon, including thermal properties and stabilization, photochemical and nonthermal chemical modification, protein modification, and biocompatibility. The book then builds on the systematic detailing of each biomedical application using porous silicon, such as vaccine development, drug delivery, and tissue engineering. It also contains new insights on in-vivo assessment of porous silicon, photodynamic and photothermal therapy, micro- and nanoneedles, cancer immunotherapy, and more. Drug Delivery and Biomedical Applications of Porous Silicon-Based Nanocarriers is of interest to researchers in the fields of materials science, nanotechnology, pharmaceutical science, biomedical engineering, and cancer research.
1. Introduction to targeted, controlled, and responsive nanoscale drug delivery systems
2. Synthesis methods of porous silicon-based nanoparticles
3. Mesoporous silica nanoparticles for therapeutic uses
4. Mesoporous silicon-based nanocarriers for improvement of water-soluble drugs
5. Porous silicon-based nanocarriers for tumor targeting
6. Porous silicon and related composites for topical drug delivery
7. Porous silicon-based nanocarriers for neurodegenerative disorders
8. Functionalized silica-based nanocarriers for blood-brain barrier targeted delivery
9. Porous silicon-based materials in nano- and microneedles-based drug delivery systems
10. Porous silicon-based nanocarriers for cancer and immune therapy
11. Stimuli-responsive silica nanoparticles: Smart systems for controlled drug release
12. Mesoporous silica-based nanocarriers in pulmonary drug delivery
13. Porous silicon nanoparticles for improved cellular uptake and targeted drug delivery
14. Recent advances in porous silicon-based technology for biomedical applications
15. Immunotherapeutic applications of porous silicon
16. Modified porous silicon nanoparticles in drug delivery
17. Bioengineered porous silicon nanoparticles in vaccine development
18. Silica nanoparticles in clinical trials
19. Future perspectives of mesoporous silica-based nanocarriers
Rajendra Awasthi is Professor of Pharmaceutics at Department of Pharmaceutical Sciences, School of Health Sciences & Technology, University of Petroleum and Energy Studies, UPES, Dehradun, India.
Santosh Kumar Singh is a Senior Scientist at the Centre of Experimental Medicine & Surgery, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.
Anurag Kumar Singh is a Research Associate in Department of Pharmaceutical Engineering and Technology, Indian Institute of Technology (Banaras Hindu University), Varanasi, India.
