This new text assist students in understanding the important science underpinning the formulation of modern dosage forms and how pharmaceutical and biopharmaceutical formulations are developed. The book covers topics from basic drug delivery to the future, including machine learning and sustainability approaches.
This new text assist students in understanding the important science underpinning the formulation of modern dosage forms and how pharmaceutical and biopharmaceutical formulations are developed. Moreover, it covers the design and development of a wide range of pharmaceutical formulations and problem-solving issues associated with their production. The chapters support undergraduate and graduate students to develop the knowledge required for their studies or prepare for employment in the pharmaceutical industry that is estimated to be worth $1.42 trillion. The book covers topics from basic drug delivery to the future, including machine learning and sustainability approaches.
Chapter 1 Drug delivery systems (DDSs): from early development to modern
ones.
Chapter 2 Physicochemical properties of drug substances.
Chapter 3
Excipients and their role in drug formulation.
Chapter 4 Pre-formulation
studies.
Chapter 5 Mechanism-Based Pharmacokinetic-Pharmacodynamic Modeling
in Advanced Drug Delivery Systems.
Chapter 6 In vitroIn vivo Correlations
(IVIVC).
Chapter 7 Pharmaceutical emulsions.
Chapter 8 Oral Solid Dosage
Forms
Chapter 9 Bioadhesive buccal delivery systems.
Chapter 10 Biologics Drug
Delivery.
Chapter 11 Drug delivery systems: from nano to micro to macro.
Chapter 12 Nano-based gene delivery systems for engineering immune cells.
Chapter 13 Injectable Drug Delivery.
Chapter 14 Drug Delivery to the Central
Nervous System.
Chapter 15 Nasal Drug Delivery.
Chapter 16 Pulmonary Drug
Delivery.
Chapter 17 Ocular Drug Delivery.
Chapter 18 Transdermal Drug
Delivery.
Chapter 19 Intravaginal Drug Delivery.
Chapter 20 Generic Drug
Development & Biosimilars.
Chapter 21 Personalised drug delivery systems.
Chapter 22 Manufacturing of Sterile Pharmaceutical Products.
Chapter 23
Ensuring Quality of Pharmaceuticals: Regulatory and Quality by Design (QbD).
Chapter 24 Machine learning and deep learning in drug delivery.
Chapter 25
Sustainability in drug delivery: A green future.
Chapter 26 Emerging
Technologies in Drug Delivery.
Chapter 27 Advanced Characterization
Techniques for Drug Delivery Systems: Tools and Applications
Professor Dimitrios A. Lamprou (Ph.D. MBA) is a subject matter expert in emerging pharmaceutical and biopharmaceutical technologies, with a focus on the development and manufacturing of sustainable drug delivery systems, advanced medical devices, and biocompatible implants. Currently, has authored more than 180 peer-reviewed publications and delivered over 200 invited talks at leading institutions and international conferences. His contributions to pharmaceutics and biomedical engineering have also earned him a place on Stanford Universitys prestigious list of the worlds top 2% of scientists, an honour he has received for several consecutive years.
Dr Matthew Wylie (Ph.D., MPharm) is a Lecturer in Pharmaceutical Materials Science at the School of Pharmacy, Queens University Belfast. His research focuses on the design and characterisation of novel stimuli-responsive biomaterials and polymeric functional coatings for drug delivery applications, with a key interest in applying these responsive materials in clinical applications, such as targeted oral drug delivery, and the development of next-generation functional coatings for medical devices and implants. Currently, he has authored over 30 peer-reviewed publications and regularly presents his research at international conferences.
