There are many potent drugs available for many diseases of the brain (e.g. Alzheimer's Disease, Parkinson's Disease, Multiple Sclerosis, Stroke, Brain tumors) The effectiviness however is not optimal since barriers in the brain prevent the drugs from reaching the brain in sufficient therapeutic concentrations (e.g. the blood-brain barrier and the blood-cerebrospinal fluid barrier).
Drug Transport(ers) and the Diseased Brain contains the papers of a timely symposium held in Spain between 6 and 9 October 2004, which sets out not only the point of view of the academic researcher and the clinician, but also from the pharmaceutical industrial on how to overcome these barriers and how to treat brain diseases effectively.
- Blood-brain barrier and blood-cerebrospinal fluid-barrier drug transport;
- Drug targeting to the brain;
- Drug transporters at barriers in the brain