Many of the consumer products and their underlying chemistry that are a part of our daily lives have negative effects on the health of humans and animals.
Environmental Contaminants and Endocrine Health focuses specifically on contaminants with hormonal disrupting activities. It provides insight into the multiple effects of endocrine-disrupting chemicals (EDCs) and their mechanism of action (MoA) on metabolism, reproduction and the multiple physiological roles of the endocannabinoid system which has recently been indicated as new target. Divided into four distinct sections the content systematically covers EDC sources and effects; EDCs as sources of disease and health impairment in laboratory models; EDCs as the cause of disease and health impairment in humans and wild species; and the removal of hazardous pollutants from wastewaters to highlight intervention, mitigation and adaptation for both reduced health threat and reduced environmental damage. Contents will contribute to the implementation and improvement of prevention efforts to reduce the health risk of EDCs as well as the reduction of the financial burden of endocrine disrupting related health care costs while helping to maintain the biodiversity of wild populations and ecosystems. This content will be a foundational resource for academic and research staff in endocrinology and hormone toxicology as well as for professors, researchers and students in these areas.
- Includes important foundational coverage of the endocrine system, definitions of EDC sources and descriptions, model examples and mechanisms of action biological effects
- Complete coverage of EDC effects in humans and animals from metabolic alterations to epidemiological studies of fertility and metabolism
- Provides insight into the confirmed and suspected human diseases spectrum with origins linked to EDC exposure including cancers, intellectual disabilities, autism, birth defects of the urethra (hypospadias), decreased sperm count, increased rates of miscarriage, obesity, type 2 diabetes, and more
Arvustused
"This books goal is to provide an overview of endocrine-disrupting chemicals (EDCs) that lead to endocrine disorders and impact humans and wildlife. The purpose is to highlight the many factors and chemicals that play a role in possible endocrine disorders in humans and wildlife, ways to dispose of such chemicals, and current trends. The book does meet this worthy objective in that it provides many references as well as studies and real-life examples One aspect of the book that is very useful and well done is that it gives approaches to investigate chemicals that may impact people then provides a study and survey to convey those points. It also goes into depth on common diseases that these chemicals may affect." --©Doodys Review Service, 2024, Michael ShiFeng Gong, M.D (Mayo Graduate School of Medicine)
1. Endocrine-disrupting chemical sources and effects
2. Endocrine-disrupting Chemicals as source of disease and health impairment in laboratory models
3. Endocrine-disrupting chemicals; cause of disease and health impairment in human and wild species
4. Removal of Hazardous Pollutants from Wastewaters
Dr. Oliana Carnevali, PhD, Professor of Developmental Biology, Polytechnic University of Marche, Italy Dr. Carnevalis research focuses on reproductive and developmental biology of fish models. Her focus is on the effects of probiotics on fish welfare. Her group also has substantial interest in reproductive toxicology to monitor environmental risk. A wide spectrum of aspects such as embryo development, reproduction, energy metabolism, immune system and genotoxic aspects, on different fish models are evaluated. She is a partner of the BioMedAqu project, supervisor of ESR10, a project focusing on skeletal pathologies in human and fish providing evidence on the effects of micronutrients and probiotics in bone cell differentiation in fish. In addition, the in vivo effects of vitamins and probiotic by parental and larval exposure on skeletal formation will be tested on zebrafish, seabream and meagre. A multidisciplinary approach including transcriptomic, histology, cell biology, infrared micro spectrometry and Raman, will be used. Dr. Gary Hardiman, PhD, Professor, Faculty of Medicine, Health and Life Sciences, School of Biological Sciences, Queens University, Ireland Dr. Hardman works in the field of systems biology the objective of which is the study of biological systems, including genes, RNAs, proteins, metabolites and cells in a focused manner, and organs, organisms and populations in a broader context. Areas of research focus include studying the effects of man-made contaminants on marine and human health; studying prostate cancer in the context of racial differences and nutritional deficiency; examining the impacts of long term space travel specifically the effects of nutrition, torpor, space radiation and microgravity on hepatic and intestinal biology; developing a rat model of opioid abuse to better understand the biological basis for substance abuse disorders and advance development of preventive strategies and more efficacious treatments; and developing a robust toolkit for better integration of Omics data sets into genotype-phenotype predictions. He maintains active research collaborations with groups in the USA, Italy, Ireland and Scotland.
