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Evidence-Based Endocrinology 3rd edition [Pehme köide]

3.50/5 (3 hinnangut Goodreads-ist)

Pauline M Camacho

Formaat: Paperback / softback, 432 pages, kõrgus x laius: 127x203 mm, kaal: 454 g, 2
Ilmumisaeg: 29-May-2012
Kirjastus: Lippincott Williams and Wilkins
ISBN-10: 145111091X
ISBN-13: 9781451110913

Teised raamatud teemal:

Endocrinology - (Hetkel poes: 2 nimetust)
Metabolism

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Formaat: Paperback / softback, 432 pages, kõrgus x laius: 127x203 mm, kaal: 454 g, 2
Ilmumisaeg: 29-May-2012
Kirjastus: Lippincott Williams and Wilkins
ISBN-10: 145111091X
ISBN-13: 9781451110913

Teised raamatud teemal:

Endocrinology - (Hetkel poes: 2 nimetust)
Metabolism

Püsilink: https://www.kriso.ee/db/9781451110913.html

Märksõnad:

This pocket-sized quick-reference handbook presents evidence-based recommendations for diagnosis and treatment of endocrine disorders. The authors summarize the latest and best clinical studies supporting the practice recommendations and grade each study to indicate the benefits and risks of the therapy and the reliability of the study results. Chapters cover disorders in the major areas of endocrinology--hypothalamic-pituitary, thyroid, adrenal, metabolic bone, reproductive, diabetes, lipid disorders, obesity and nutrition, endocrine malignancies, and genetics.

Arvustused

"This is a concise, easy-to-read, high-yield clinical summary of the major endocrine diseases that highlights clinical studies pertinent to epidemiology, diagnosis, and management. This edition, updated from 2006, also covers imaging technologies currently used in research settings as well as potential upcoming treatment options in clinical trials." "It proficiently highlights landmark and recent clinical studies on diagnostic and therapeutic aspects of management, including upcoming technologies and therapies, and this justifies replacing the previous edition."

- Doody's Book Review (January 2013) Sharon H Chou, MD(University of Chicago Medical Center)

Contributors

Preface

vii

Acknowledgments

viii

Introduction

xxi

1 Hypothalamic-Pituitary Disease

(42)

Gerald Charnogursky

Nicholas Emanuele

Mary Ann Emanuele

Hong Lee

Shanika Samarasinghe

Introduction of the Hypothalamic-Pituitary Axis

(1)

Pituitary Adenomas

(4)

Epidemiology and Pathogenesis

(1)

Diagnosis

(1)

Treatment

(1)

Overview

(1)

Surgery

(1)

Postoperative Complications

(1)

Radiation

(1)

Hypopituitarism

(9)

Pathophysiology

(1)

Clinical Findings

(1)

Secondary Adrenal Insufficiency

(2)

Central or Secondary Hypothyroidism

(1)

Secondary Hypogonadism

(1)

Growth Hormone Deficiency

(2)

Prolactin Deficiency

(1)

Treatment

(1)

Prolactin

(1)

Pituitary Hormone Excess

(1)

Thyrotropin Excess

(1)

Nonfunctional Adenomas and Gonadotropin-Producing Adenomas

(1)

Prolactin Excess

(1)

Pituitary Incidentalomas

(1)

Imaging of the Hypothalamic-Pituitary System

(2)

Radiologic Imaging Techniques

(2)

Other Sellar Lesions

(1)

Disorders of the Prolactin System

(3)

Pathophysiology

(1)

Clinical Features

(1)

Evaluation

(1)

Management

(1)

Pregnancy and Hyperprolactinemia

(1)

Acromegaly

(1)

Definition

(1)

Etiology

(1)

Epidemiology

(1)

Pathophysiology and Clinical Presentation

(1)

Diagnosis

(1)

Treatment

(1)

Neurosurgery

(1)

Somatostatin Analogs

(1)

Radiation Therapy

(1)

Dopamine Agonists

(1)

Growth Hormone Receptor Antagonist

(1)

Diabetes Insipidus

(2)

Definition

(1)

Etiology

(1)

Central Diabetes Insipidus

(1)

Nephrogenic Diabetes Insipidus

(1)

Pathophysiology

(1)

Diagnosis

(1)

Treatment

(1)

Central Diabetes Insipidus

(1)

Nephrogenic Diabetes Insipidus

(1)

Cushing Disease

(3)

Etiology and Pathogenesis

(1)

Clinical Manifestations

(1)

Laboratory Findings

(1)

High-Dose Dexamethasone Suppression Test

(1)

Bilateral Inferior Petrosal Sinus Sampling

(1)

Treatment

(1)

Syndrome of Inappropriate Antidiuretic Hormone Secretion

(3)

Etiology

(1)

Epidemiology

(1)

Pathophysiology

(1)

Diagnosis

(1)

Clinical Findings

(1)

Laboratory Findings

(1)

Treatment

(1)

Short-Term Therapy

(1)

Long-Term Therapy

(1)

Vasopressin Receptor Antagonists

(1)

References

(13)

2 Thyroid Disorders

(38)

M. Regina Castro

Hossein Gharib

Evaluation of Thyroid Function

(2)

Thyrotropin

(1)

Free Thyroxine

(1)

Total Thyroxine and Triiodothyronine

(1)

Thyroid Autoantibodies

(1)

Thyroglobulin

(1)

Thyroid Imaging

(1)

Ultrasonography

(1)

Scintigraphy

(1)

Computed Tomography

(1)

Radioiodine Uptake

(1)

131I Whole-Body Scanning

(1)

18F-Fluorodeoxyglucose Positron Emission Tomography

(1)

Hyperthyroidism

(4)

Definition

(1)

Etiology

(1)

Epidemiology

(1)

Pathophysiology

(1)

Diagnosis

(1)

Treatment

(1)

Antithyroid Drugs

(1)

Antithyroid Drugs plus LT4

(2)

Radioiodine

(1)

Surgery

(1)

β-Blockers

(1)

Hypothyroidism

(1)

Definition

(1)

Etiology

(1)

Epidemiology and Pathophysiology

(1)

Diagnosis

(1)

Treatment

(1)

Levothyroxine

(1)

LT4 plus Liothyronine (T3)

(1)

Thyroid Nodules

(2)

Etiology

(1)

Epidemiology

(1)

Diagnosis

(1)

Treatment

(1)

Surgery

(1)

Suppressive Therapy with Levothyroxine

(1)

Radioiodine Therapy

(1)

Percutaneous Ethanol Injection

(1)

Laser Thermal Ablation (2B)

(1)

Thyroid Cancer

(3)

Definition and Classification

(1)

Epidemiology

(1)

Diagnosis

(1)

Fine-Needle Aspiration Biopsy

(1)

Thyroid Function Tests

(1)

Tumor Markers

(1)

Treatment

(1)

Surgery

(1)

Radioiodine Remnant Ablation

(1)

Thyroid Hormone Suppression of TSH

(1)

Tyrosine Kinase Inhibitors

(1)

Euthyroid Sick Syndrome

(1)

Definition and Etiology

(1)

Pathophysiology

(1)

Diagnosis

(1)

Treatment

(1)

Triiodothyronine Replacement

(1)

References

(24)

3 Adrenal Disorders

(41)

Dana Erickson

Steven A. De Jong

Evaluation of Adrenal Function

(2)

Evaluation of Glucocorticoid Function

(1)

Cortisol

(1)

Adrenocorticotropic Hormone

(1)

Dynamic Adrenal Tests

(1)

Evaluation of Mineralocorticoid Function

(1)

Evaluation of Adrenal Medulla

(1)

Evaluation of Adrenal Androgen Production and Congenital Adrenal Hyperplasia in Adults

(1)

Adrenal Imaging

(3)

Computed Tomography Scanning

(1)

Magnetic Resonance Imaging

(1)

Adrenal Cortical Scintigraphy

(1)

Adrenal Medullary Scintigraphy

(1)

Positron Emission Tomography

(1)

Adrenal Vein Sampling

(1)

Primary Hyperaldosteronism

(4)

Definition and Etiology

(1)

Epidemiology

(1)

Pathophysiology

(1)

Diagnosis

(2)

Treatment

(1)

Cushing Syndrome

(3)

Etiology and Pathogenesis

(1)

Clinical Features

(1)

Evaluation

(1)

Treatment

(1)

Adrenal Incidentaloma

(3)

Definition

(1)

Etiology

(1)

Diagnosis

(1)

Treatment

(1)

Follow-Up

(1)

Adrenal Insufficiency

(4)

Definition

(1)

Etiology and Epidemiology

(1)

Pathophysiology

(1)

Diagnosis

(1)

Clinical Symptoms

(2)

Laboratory Diagnosis

(1)

Imaging Studies

(1)

Treatment

(1)

Pheochromocytoma

100

(4)

Definition and Etiology

100

(1)

Epidemiology

100

(1)

Pathophysiology

101

(1)

Diagnosis

102

(1)

Treatment

103

(1)

References

104

(18)

4 Metabolic Bone Disorders

Alaleh Mazhari

Zeina Habib

Pauline Camacho

Evaluation of Metabolic Bone Disorders

122

(2)

Serum Calcium, Phosphate, and Magnesium

122

(1)

Intact Parathyroid Hormone

122

(1)

Vitamin D Metabolites

122

(1)

Parathyroid Hormone-Related Protein

123

(1)

Calcitonin

123

(1)

Urinary Calcium Excretion

123

(1)

Biochemical Markers of Bone Turnover

123

(1)

Bone-Formation Markers

123

(1)

Bone-Resorption Markers

123

(1)

Clinical Use

124

(1)

Bone Imaging

124

(3)

Bone Densitometry

125

(1)

Scintigraphy

126

(1)

Quantitative Computed Tomography

126

(1)

Micro-Computed Tomography

126

(1)

Quantitative Ultrasound

126

(1)

Magnetic Resonance Imaging

127

(1)

Bone Biopsy

127

(1)

Osteoporosis

127

(19)

Definition

127

(1)

Epidemiology

127

(1)

Pathophysiology

127

(1)

Diagnosis

127

(1)

Prevention

127

(1)

Fracture Risk Assessment

128

(1)

Treatment

129

(1)

Bisphosphonates

130

(4)

Safety Concerns

134

(1)

Esophagitis

134

(1)

Osteonecrosis of the Jaw

134

(1)

Atrial Fibrillation

134

(1)

Atypical Femoral Fractures

134

(3)

Esophageal Cancer

137

(1)

Raloxifene

137

(1)

Calcitonin

138

(1)

Hormone Replacement Therapy

138

(1)

Combination Therapy

138

(1)

Teriparatide (PTH 1-34)

138

(3)

Safety Concerns

141

(3)

Other Therapies

144

(1)

Future Therapies

144

(2)

Monitoring Therapy

146

(1)

Paget Disease of Bone

146

(3)

Epidemiology

147

(1)

Pathophysiology

147

(1)

Diagnosis

147

(1)

Treatment

147

(1)

Bisphosphonates

147

(2)

Calcitonin

149

(1)

Other Therapies

149

(1)

Primary Hyperparathyroidism

149

(4)

Epidemiology

149

(1)

Pathogenesis

149

(1)

Clinical Presentation

150

(1)

Diagnosis

150

(1)

Treatment

151

(1)

Surgical Management

151

(1)

Medical Management

152

(1)

Parathyroid Carcinoma

153

(1)

Epidemiology

153

(1)

Pathogenesis

153

(1)

Clinical Manifestations

153

(1)

Diagnosis

154

(1)

Treatment

154

(1)

Hypercalcemia

154

(4)

Diagnosis

154

(1)

Treatment

155

(1)

Address the Primary Cause

155

(1)

Decrease Intestinal Absorption

155

(1)

Increase Urinary Calcium Excretion

155

(1)

Inhibit Bone Resorption

156

(1)

Dialysis

157

(1)

Hypercalcemie Emergencies

157

(1)

Future Therapy

157

(1)

Hypocalcemia

158

(2)

Diagnosis

158

(1)

Treatment

158

(1)

Hypocalcemic Emergencies

158

(1)

Oral Calcium Supplements

159

(1)

Vitamin D

159

(1)

Magnesium

160

(1)

Parathyroid Hormone

160

(1)

Osteomalacia

160

(2)

Vitamin D-Dependent Rickets (Type 1 and Type 2)

161

(1)

Oncogenic Osteomalacia

161

(1)

Hypophosphatemic Rickets

161

(1)

Hypophosphatasia

162

(1)

Drug-Induced Osteomalacia

162

(1)

Vitamin D Deficiency

162

(2)

Sources of Vitamin D

162

(1)

Prevalence

162

(1)

Risk Factors

163

(1)

Skeletal Effects

163

(1)

Nonskeletal Effects

163

(1)

Clinical Presentation

164

(1)

Diagnosis

164

(1)

Treatment

164

(1)

References

164

(26)

5 Reproductive Disorders

190

(39)

Neil Goodman

Rhoda H. Cobin

Amenorrhea

190

(4)

Definition

190

(1)

Etiology

190

(1)

Epidemiology

190

(1)

Pathophysiology

190

(1)

Primary Amenorrhea

191

(1)

Secondary Amenorrhea

192

(1)

Diagnosis

193

(1)

Treatment

193

(1)

Hyperandrogenism and PCOS

194

(3)

Hyperandrogenism

194

(3)

PCOS

197

(1)

PCOS and Insulin Resistance (Metabolic Syndrome)

197

(3)

Diagnosis

198

(1)

Treatment

198

(2)

Insulin-Sensitizing Drugs

200

(1)

Precocious Puberty

200

(2)

Definition

200

(1)

Pathophysiology

200

(1)

Etiology and Diagnosis

200

(1)

Treatment

201

(1)

Male Hypogonadism

202

(4)

Definition

202

(1)

Etiology and Diagnosis

203

(1)

Congenital Male Hypogonadism

203

(1)

Acquired Male Hypogonadism

203

(2)

Treatment

205

(1)

Treatment Outcomes

206

(1)

Infertility

207

(2)

Definition

207

(1)

Epidemiology

207

(1)

Etiology

207

(1)

Evaluation

207

(1)

Treatment

208

(1)

Menopause

209

(1)

Definition

209

(1)

Diagnosis

209

(1)

Treatment

209

(1)

References

210

(19)

6 Diabetes Mellitus

229

(50)

Haitham S. Abu-Lebdeh

Gregg D. Simonson

Type 1 Diabetes Mellitus

229

(6)

Definition

229

(1)

Etiology

229

(1)

Genetics

229

(1)

Major Histocompatibility Complex Genes

229

(1)

Insulin-Dependent Diabetes Mellitus Genes

230

(1)

Rare Forms

230

(1)

Epidemiology

230

(1)

Pathophysiology

230

(1)

Diagnosis

230

(1)

Screening

230

(1)

Clinical Manifestations

231

(1)

Laboratory Findings

231

(1)

Prevention

231

(1)

Treatment

232

(1)

Insulin

232

(1)

Insulin Regimens

232

(2)

Diet

234

(1)

Exercise

234

(1)

Blood Glucose Monitoring

234

(1)

Transplantation

235

(1)

Diet

235

(1)

Type 2 Diabetes Mellitus

235

(9)

Definition

235

(1)

Etiology

235

(1)

Risk Factors

235

(1)

Epidemiology

236

(1)

Pathophysiology of Type 2 Diabetes Mellitus

236

(1)

Diagnosis

236

(1)

Clinical Manifestations

236

(1)

Laboratory Findings

237

(1)

Screening

237

(1)

Prevention

237

(1)

Treatment

238

(1)

Weight Reduction and Dietary Restrictions

238

(1)

Exercise

238

(1)

Oral Drug Therapy

238

(3)

Noninsulin Injectable Therapies

241

(2)

Combination Therapy

243

(1)

Transplantation

244

(1)

Diabetic Ketoacidosis

244

(3)

Definition

244

(1)

Etiology

244

(1)

Epidemiology

244

(1)

Pathophysiology

244

(1)

Diagnosis

245

(1)

Laboratory Findings

245

(1)

Clinical Manifestations

245

(1)

Treatment

245

(1)

Fluid Replacement

245

(1)

Insulin

245

(1)

Bicarbonate

246

(1)

Potassium

246

(1)

Phosphate

246

(1)

Monitoring Therapy

246

(1)

Prognosis

246

(1)

Hyperosmolar Coma

247

(1)

Definition

247

(1)

Etiology

247

(1)

Pathophysiology

247

(1)

Epidemiology

247

(1)

Diagnosis

247

(1)

Clinical Manifestations

247

(1)

Laboratory Findings

247

(1)

Treatment

247

(1)

Fluids

247

(1)

Insulin

248

(1)

Electrolytes

248

(1)

Hypoglycemia

248

(3)

Definition

248

(1)

Classification

248

(1)

Etiology

248

(1)

Pathophysiology

249

(1)

Epidemiology

249

(1)

Type 1 Diabetes Mellitus

249

(1)

Type 2 Diabetes Mellitus

249

(1)

Diagnosis

249

(1)

Clinical Manifestations

249

(1)

Treatment

250

(1)

Hypoglycemia Unawareness

250

(1)

Complications

250

(1)

Cardiovascular Disease

251

(8)

Epidemiology

251

(1)

Etiology

251

(1)

Diagnosis

251

(1)

Prevention and Treatment

251

(2)

Eye Disease

253

(1)

Etiology

253

(1)

Pathophysiology

253

(1)

Epidemiology

254

(1)

Diagnosis

254

(1)

Prevention and Treatment

254

(1)

Diabetic Neuropathy

255

(1)

Classification

255

(1)

Pathophysiology

255

(1)

Epidemiology

255

(1)

Diagnosis

256

(1)

Treatment

256

(1)

Renal Disease

257

(1)

Definition

257

(1)

Etiology

257

(1)

Pathophysiology

257

(1)

Epidemiology

257

(1)

Diagnosis

257

(1)

Prevention and Treatment

258

(1)

Intensive Glycemic Management

259

(3)

Definition

259

(1)

Etiology/Rationale

259

(1)

Outpatient Setting

259

(1)

Type 1 DM

259

(1)

Type 2 DM

260

(1)

The Inpatient Setting

260

(1)

Epidemiology

260

(1)

Pathophysiology

260

(2)

References

262

(17)

7 Lipid Disorders

279

(21)

Francis Q. Almeda

Susan DeLange

Lipoprotein Metabolism

279

(2)

Low-Density Lipoprotein Cholesterol

281

(7)

Trials

281

(1)

Primary Prevention Trials

281

(3)

Secondary Prevention Trials

284

(1)

How Low Should You Go?

284

(1)

Treatment Options

285

(1)

Dietary Modification

285

(1)

Statins (3-Hydroxy-3-Methylglutaryl Coenzyme A Reduetase Inhibitors)

285

(1)

Statin Therapy in High-Risk Populations

285

(2)

Ezetimibe (Zetia)

287

(1)

Bile Acid Sequestrants (Resins)

288

(1)

Nicotinic Acid and Fibric Acids

288

(1)

Combination Therapy

288

(1)

Nonpharmacologic Strategies

288

(1)

High-Density Lipoprotein Cholesterol and Triglycerides

288

(3)

Treatment Options

289

(1)

Therapeutic Lifestyle Changes

289

(1)

Nicotinic Acid (Niacin)

289

(1)

Fibric Acids (Fibrates)

289

(1)

Statins

290

(1)

Fish Oils

290

(1)

New Treatment Options for Increasing HDL

290

(1)

Lipoprotein(A)

291

(1)

Homocysteine

291

(1)

Future Directions

291

(1)

References

292

(8)

8 Obesity and Nutrition

300

(22)

Jeffrey I. Mechanick

Elise M. Brett

Definition

300

(1)

Epidemiology

301

(1)

Etiology

301

(1)

Pathophysiology

302

(1)

Treatment

302

(5)

Therapeutic Lifestyle Changes

303

(1)

Behavioral

303

(1)

Healthy Eating and Nutrition

304

(2)

Physical Activity

306

(1)

Pharmacotherapy

307

(1)

Orlistat

307

(1)

Phentermine

307

(1)

Diethylpropion

307

(1)

History

307

(1)

Future Directions

308

(1)

Bariatric Surgery

308

(1)

References

309

(13)

9 Multiple Endocrine Neoplasia

322

(26)

Glen Sizemore

Norma Lopes

Men Type 1

324

(5)

Screening

324

(1)

Enteropancreatic Disease

325

(1)

Gastrin-Secreting Tumors

325

(1)

Diagnosis

325

(1)

Treatment

326

(1)

Insulin-Secreting and Other Tumor Types

327

(1)

Diagnosis

327

(1)

Treatment

327

(1)

Parathyroid Disease

327

(1)

Diagnosis

327

(1)

Treatment

328

(1)

Pituitary Disease

328

(1)

Associated Diseases

329

(1)

Men Type 2

329

(6)

Screening

329

(1)

Medullary Thyroid Carcinoma

330

(1)

Diagnosis

330

(1)

Treatment

330

(3)

Pheochromocytoma

333

(1)

Diagnosis

333

(1)

Treatment

334

(1)

Parathyroid Disease

335

(1)

Treatment

335

(1)

Should Patients with Thyroid Nodules be Screened for MTC?

335

(1)

References

336

(12)

10 Carcinoid Tumors

348

(7)

Nathan J. O'Dorisio

Thomas M. O'Dorisio

M. Sue O'Dorisio

Definition

348

(1)

Etiology

348

(1)

Epidemiology

349

(1)

Pathology

349

(1)

Diagnosis

350

(1)

Biomarkers

350

(1)

Treatment

351

(1)

References

352

(3)

11 Paraneoplastic Endocrine Syndromes

355

(17)

Subhash Kukreja

Hypercalcemia of Malignancy

355

(5)

Definition

355

(1)

Etiology

356

(1)

Epidemiology

357

(1)

Pathophysiology

357

(1)

Diagnosis

358

(1)

Treatment

358

(1)

Prognosis

359

(1)

Antiresorptive Agents (Bisphosphonates and Denosumab) for Treatment of Bone Metastases

359

(1)

Hypoealeemia

360

(1)

Tumor-Induced Osteomalacia

360

(1)

Ectopic Adrenocorticotropic Hormone Syndrome

361

(2)

Non-Islet Cell Tumor-Induced Hypoglycemia

363

(1)

Acromegaly

363

(1)

Hyperthyroidism

364

(1)

References

364

(8)

12 Genetics

372

(21)

Peter Kopp

Definition

372

(5)

Etiology

377

(1)

Epidemiology

378

(1)

Pathophysiology

379

(1)

Diagnosis

379

(5)

Approach to the Patient

379

(1)

Information about Genetic Disorders

380

(1)

Genetic Counseling

380

(1)

Genetic Testing

380

(1)

Sample Collection

381

(1)

Laboratories Performing Genetic Tests

381

(1)

Practical Limitations of Genetic Testing

382

(2)

Treatment

384

(1)

Acknowledgments

384

(1)

References

384

(9)

Index

393

Evidence-Based Endocrinology 3rd edition [Pehme köide]

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Konto & seaded

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Otsingu andmebaas

Filtreeri tulemusi

Teemad Ingliskeelsed raamatud

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