This book is intended to serve as a comprehensive guide to navigate this rapidly evolving landscape of extracellular vesicles (EVs). It provides a thorough understanding of EVs, ranging from their basic biology to their cutting-edge uses in diagnostics and therapeutics. Its primary objective is to systematically bridge the foundational principles of EV biology with their practical and transformative clinical applications. The book is structured to serve a diverse readershipfrom students and researchers embarking on EV studies to clinicians and industry professionals seeking to harness their potential. The text contains 14 chapters, all of which have been authored by leading international experts that provide authoritative insights into their respective specialties. Early chapters provide the critical methodological backbone necessary for rigorous scientific inquiry. Later chapters address the translational momentum in the field, as well as detail how EVs are revolutionizing approaches to cancer, neurodegenerative, cardiovascular, and other diseases. Finally, the book concludes by discussing the ethical issues in EV research and application, ensuring progress is matched with responsibility. By consolidating current knowledge and highlighting future trajectories, Extracellular Vesicles: From the Laboratory to the Clinic aims to accelerate the responsible translation of EV science into tangible clinical solutions that improve patient outcomes worldwide.
Understanding Extracellular Vesicles.- Characterization and
Quantification of Extracellular Vesicles.- Extracellular Vesicle Functional
Analysis.- Stem Cell-Derived Extracellular Vesicles in treatment of disease.-
Platelet-Derived Extracellular Vesicles in treatment of disease.-
Milk-Derived Extracellular Vesicles in treatment of disease.-
Bacterial-Derived Extracellular Vesicles in treatment of disease.-
Plant-Derived Extracellular Nanovesicles in treatment of disease.- EVs in
Disease Diagnostics.- Therapeutic Potential of EVs.- Theranostics Potential
of EVs.- EVs in Personalized Medicine.- Translational Research.- Ethical
Issues in EV Research and Application.
Mohsen Sheykhhasan Cellular and Molecular Research Center Qom University of Medical Sciences Qom, Iran
Piao Yang Department of Molecular Genetics The Ohio State University Columbus, OH USA
Pouria Samadi Poursina Hakim Digestive Diseases Research Center Isfahan University of Medical Sciences Isfahan, Iran
Hamed Manoochehri The Persian Gulf Marine Biotechnology Research Center, The Persian Gulf Biomedical Sciences Research Institute Bushehr University of Medical Sciences, Bushehr, Iran