INCLUDES COURSE ID FOR ONLINE CME QUESTIONS AND ACCREDITATION
The essential textbook for HIV care providers and pharmacists-updated for 2025!
The 2025 edition of Fundamentals of HIV Medicine continues to act as an indispensable resource for practitioners dedicated to the prevention and treatment of HIV. This comprehensive textbook covers both clinically useful principles of HIV medicine and the latest scientific bases for these principles, as they apply to supplying healthcare to individuals affected by HIV.
Updated to reflect recent advancements, this clear and coherent textbook offers readers the benefit of over 40 years of collective HIV medical knowledge and experience caring for people affected by HIV. Fundamentals of HIV Medicine 2025 delves into antiretroviral therapies, including long acting injectables, and presents insights into holistic patient management. This new edition offers continuing education for all healthcare professionals involved in HIV care.
Designed to meet the evolving educational needs of clinicians and professionals, the maturity and reliability of the overarching principles of HIV medicine and patient care are increasingly evident in this 9th consecutive edition, which embodies the American Academy of HIV Medicine's commitment to excellence.
Updated to reflect recent advancements, Fundamentals of HIV Medicine 2025 offers readers the benefit of over 40 years of collective HIV medical knowledge and experience caring for people affected by HIV. This clear and coherent textbook delves into antiretroviral therapies, including long acting injectables, and presents insights into holistic patient management. The new edition offers continuing education for all healthcare professionals involved in HIV care.
Overall Learning Objectives
Faculty
Conflicts of Interest Disclosures
Disclosure of Unlabeled Use
Preface
Carolyn Chu, MD, MD, MSc
1. Ending the HIV Epidemic: A Plan for America
Benjamin Sokoloff
2. The Origin, Evolution, and Epidemiology of HIV-1 and HIV-2
Jeffrey T. Kirchner, Emily Min, and Julia Taylor
3. Mechanisms of HIV Transmission
Nancy Aitcheson and Puja H. Nambiar
4. Virology: Lifecycle of HIV
Poonam Mathur, George Lewis
5. Immunology of HIV Infection
Dennis J. Hartigan-O'Connor and Christian Brander
6. HIV Testing and Counseling
M. Elle Saine and Kyle G. Rodino
7. Initial Evaluation of The Patient with HIV: History, Physical Examination,
and Laboratory Evaluation
Esteban DelPilar Morales
8. Health Maintenance: Select Topics
Ramiz Kseri
9. Diversity and Health Disparities
Gary F. Spinner
10. HIV Care and Prevention: Special Populations
Catherine Silva, Renata Arrington-Sanders, Zil G. Goldstein, , Elizabeth
Imbert, Matthew D. Hickey, Olabimpe Asupoto, Alysse Wurcel, Abby Davids,
Ashley Carvalho, Deliana Garcia, Claire Hutkins Seda, and Laszlo Madaras
11. HIV Care Coordination
Margret O. Nelson
12. The Pharmacist's Role in HIV Care
Jennifer Cocohoba
13. Principles and Scientific Basis of HIV Therapy
Neha Sheth Pandit, David E. Koren, and Emily L. Heil
14. HIV Prevention: Pharmacotherapy and Non-Pharmacotherapy-based Strategies
Katrina Baumgartner, Christopher M. Bositis, Wyatt Hanft, Carolyn Chu
15. Antiretroviral Therapy Selection/Decision-Making: Initial and Subsequent
Regimens
Saira Ajmal, Zelalem Temesgen, Poonam Mathur and David E. Koren
16. Antiretroviral Treatment and Stewardship in Hospital Settings
David E. Koren and Yoseph Aldras
17. HIV Drug Resistance: Evaluation and Clinical Management
Carolyn Chu, Avani Dalal, and Robert Shafer
18. The HIV Reservoir and Cure and Remission Strategies
Boris Juelg, Rajesh T. Gandhi, and Nikolaus Jilg
19. Opportunistic Infections
Lisa Armitige, Karen J. Vigil, and Rita Wilson Dib
20. Immune Reconstitution Inflammatory Syndrome (IRIS)
Dagan Coppock
21. Antiretroviral Therapy for Children and Newborns
Karin Nielsen-Saines
22. Select Topics in the Care of Cis-gender Women with HIV
Aasith Villavicencio Paz, Jillian T. Baron, Christina E. Maguire, and William
R. Short
23. Aging and HIV
Aroonsiri Sangarlangkarn, John D. Zeuli, and Anchalee Avihingsanon
24. Solid Organ Transplantation in Persons With HIV
Christine M. Durand
25. Malignancies in HIV
Eva H. Clark and Elizabeth Y. Chiao
26. Understanding and Managing Antineoplastic and Antiretroviral Therapy
Elizabeth M. Sherman and Taylor K. Gill
27. Dermatologic Complications of HIV
Craig Weeks
28. Neurological Complications of HIV Infection
Rodrigo Hasbun and Joseph S. Kass
29. Cardiovascular Disease
Jarrett K. Sell and Jonathan J. Nunez
30. Non-Opportunistic Pulmonary Complications
Priyanka Chakrabarti
31. Renal Complications
Patricia Carr Reese and Umar Farooq
32. Endocrine Disorders and Metabolic Complications In HIV
Daniel Lee
33. HIV and Bone Health
Roger Bedimo
34. Substance Use and HIV
Thanh Thuy Truong
35. Psychiatric Disorders and HIV
Richa Vijayvargiya and Elizabeth David
36. HIV and Hepatitis Coinfection
Karen J. Vigil
37. Sexually Transmitted Infections
Karen J. Vigil
38. Legal Issues
Anna Kastner
39. HIV Healthcare Programs and Insurance Coverage in the US Healthcare
System
Chauncey McGlathery
Index
About the Editor-in-Chief:
Carolyn Chu, MS, MSc, AAHIVS is the Chief Clinical Officer/Primary Investigator of the National Clinician Consultation Center, a federally supported educational resource program founded in 1993 to offer low barrier, person-centered guidance on HIV, hepatitis, and substance use. Dr. Chu completed a Family Medicine residency and clinical research fellowship at Montefiore Medical Center/Albert Einstein College of Medicine in the Bronx, NY, and previously served as Medical Director for a large network of community health centers in New York City. She is a UCSF Professor of Clinical Family and Community Medicine and provides health care at San Francisco General Hospital's Family Health Center.
About the American Academy of HIV Medicine (AAHIVM):
The American Academy of HIV Medicine stands as the nation's foremost independent organization of healthcare professionals committed to excellence in HIV care and prevention. The Academy's membership of
practitioners and credentialed clinicians manage the health of most people living with or at risk for HIV in the United States. The HIV-centered credentialing programs promote standards of care as an independent verification of a provider's knowledge of HIV and HCV care, professional ethics, and overall sexual health competencies. The HIV Specialist ("AAHIVS"), HIV Expert ("AAHIVE"), and HIV Pharmacist ("AAHIVP") are the only credentials designated specifically for HIV care providers in the United States.
