Providing a multidisciplinary approach to genetic vaccines, this text covers different aspects of basic immunology, molecular biology, infectious diseases, and allergy, as well as the regulatory approach to the emerging field of DNA vaccination.
Introduction: Gene Vaccination, Current Concepts and Future Directions 1(8) E. RAZ Plasmid DNA Vaccination: Mechanism of Antigen Presentation 9(8) M. CORR H. TIGHE The Development of a Multivalent DNA Vaccine for Malaria 17(14) R.C. HEDSTROM D.L. DOOLAN R. WANG M.J. GARDNER A. KUMAR M. SEDEGAH R.A. GRAMZINSKI J.B. SACCI JR. Y. CHAROENVIT W.R. WEISS M. MARGALITH J.A. NORMAN P. HOBART S.L. HOFFMAN DNA Vaccination with Co-Stimulatory Molecules 31(8) R. MENDOZA T.J. KIPPS Gene Immunization for the Induction of Antigen-Specific, Non MHC-Restricted Responses 39(12) D.J. LEE D.A. CARSON M. CORR DNA Vaccines With Rapid Intracellular Degradation are More Effective for Inducing CTL 51(8) Y. WU T.J. KIPPS Genetic Vaccination Against Tuberculosis 59(14) D.B. LOWRIE C.L. SILVA R.E. TASCON DNA Gene Vaccination for HIV 73(20) J.J. KIM D. WEINER DNA-Based Immunization Against Hepatitis B Virus 93(16) H.L. DAVIS C.L. BRAZOLOT MILLAN Gene Vaccination for Hepatitis C 109(12) G. INCHAUSPE Gene Immunization for Allergic Disorders 121(10) M. ROMAN H.L. SPIEGELBERG D. BROIDE E. RAZ Immunization With DNA Vaccines in Early Life: Advantages and Limitations as Compared to Convential Vaccines 131(12) C.-A. SIEGRIST P.-H. LAMBERT DNA Vaccination by Somatic Transgene Immunization 143(14) M. ZANETTI S. XIONG M. GERLONI DNA Vaccines: Safety and Efficacy Issues 157(12) D.M. KLINMAN M. TAKENO M. ICHINO M. GU G. YAMSHCHIKOV G. MOR J. CONOVER Genetic Vaccines -- A Revolution in Vaccinology? 169 Z.Q. XIANG S. PASQUINI Z. HE H. DENG Y. WANG M.A. BLASZCZYK-THURIN H.C.J. ERTL
