Greenfield's is the world’s leading neuropathology reference. It provides a comprehensive account of the pathological findings in neurological disease, their biological basis, and their clinical manifestations. The 2 volume work provides a remarkable text which is clear, comprehensive and precise with exceptional illustrations. This is a tried and tested reference for scientists, clinicians, researchers, and students who wish to learn more about neurological disease. The tenth edition features fully updated sections covering CNS tumours, neurodegeneration, skeletal muscle, epilepsy, paediatric and forensic neuropathology.Global coverage from an international team of Editors and contributors.Fully downloadable and easily used e-version included.
Greenfield's 10e is the world’s leading neuropathology reference. The two volume work provides a comprehensive account of the pathological findings in neurological disease, their biological basis, and their clinical manifestations. The key reference for scientists, clinicians, researchers, and students.
Volume One. Section 1: General Pathology of the Nervous System. Diseases
of brain synapses and neuronal architecture. Astrocyte functions in health
and disease. Oligodendrocytes. Microglia. Ependymal cells and choroid plexus.
Cellular inclusions and artefacts. Basic Pathophysiology. Section 2:
Cerebrovascular Disorders.Vascular disease, hypoxia and consequences. Section
3: Developmental Neuropathology and Metabolic Disorders. Normal development
of the nervous system. Acquired disorders of childhood. Malformations.
Metabolic and degenerative disorders of childhood. Lysosomal disorders.
Peroxisomal disorders,Mitochondrial disorders. Section 4: Epilepsy.Epilepsy
pathology. Section 5: Neuroinflammatory Disorders Multiple sclerosis and
other demyelinating conditions. Other immune-related disorders affecting the
nervous system.Section 6: Neurodegenerative disorders.Neurodegenerative
diseases: classification. Pathogenesis and concepts. Movement disorders.
Degenerative ataxic disorders. Motor neuron disorders. Cognitive decline.
Neurodegenerative proteinopathies: PrP proteinopathies. Neurodegenerative
proteinopathies: Alzheimers disease (A-beta and Tau proteinopathy).
Neurodegenerative proteinopathies: Synuclein proteinopathies.
Neurodegenerative proteinopathies:Tau proteinopathies. Neurodegenerative
proteinopathies: TDP-43 proteinopathies. Neurodegenerative proteinopathies:
FUS/FET proteinopathies. Neurodegenerative proteinopathies: Trinucleotide
repeat disorders. Miscellaneous proteinopathies and neurodegenerative
conditions. Ageing-related pathologies of the brain. Mixed pathologies of the
ageing and neurodegenerating brain.Diagnostic approach to the neuropathology
of neurodegenerative diseases
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Professor Colin Smith, Chair of Neuropathology, Centre for Clinical Brain Sciences,Centre for Comparative Pathology,The University of Edinburgh, Scotland, UK. Graduated MBChB from Glasgow 1992, and FRCPath 2000. Appointed Senior Lecturer in Pathology in 2001 and has both a diagnostic and research component to his role. Main research interests lie around neurotrauma and neurovascular disease, and particularly assessment of human tissue in these disorders. Professor Tom Jacques, Professor of Paediatric Neuropathology, ICH Development Bio & Cancer Programme,UCL GOS Institute of Child Health, London, UK. Gabor G Kovacs, MD, PhD, FRCPC is Professor in the Department of Laboratory Medicine and Pathobiology at the University of Toronto, a Consultant Neuropathologist at the Laboratory Medicine Program (LMP) at the University Health Network (UHN) and a Principal Investigator at the Tanz Centre for Research in Neurodegenerative Disease. He is also a Senior Scientist at the Krembil Brain Institute, a Faculty member of the Edmond J. Safra Program in Parkinson's Disease and the Co-Director of the Rossy Program for Progressive Supranuclear Palsy Research (UHN).
