The book attempts to document the contribution of haemostasis to the understanding of renal disease and foreshadow advances yet to come from this collaboration of disciplines which contains contriubtions from a number of specialists in the field. It outlines the haemostatic mechanisms and their relationship to the functioning of the kidney. This includes sections on normal and pathological haemostatic mechanisms, haemorrhagic tendency in uraemia, thrombosis, thrombotic microangiopathy and haemostatic defects associated with dialysis and induced treatments for renal disease.
Part 1 Haemostatic mechanisms: the physiology of primary haemostasis,
G.de Gaetano et al; coagulation pathways and control mechanisms, D.Green;
fibrinolysis, Hau C.Kwaan. Part 2 Haemostatic mechanisms in the pathogenesis
of renal diseases: role of haemostasis in the pathogenesis of acute renal
failure, A.Schieppati and R.W.Schrier; primary glomerulonephritis, G.H.Nield
and J.S.Cameron; systemic lupus erythematosus and haemostasis, F.del Greco et
al; eicosanoids and platelet-activating factor as mediators of injury in
renal diseases, C.Zoja et al. Part 3 The haemorrhagic tendency in uraemia:
the uraemic platelet, G.Remuzzi and F.Pusineri; Factor VIII/von Willebrand
factor, Z.M.Ruggeri and P.M.Manucci; uraemic bleeding - clinical presentation
and management, E.Gotti and G.Remuzzi. Part 4 Thrombosis and renal disease:
hypercoagulability in the nephrotic syndrome, M.Livio; renal vein thrombosis
- clinical spectrum and management, R.P.Wagoner; sickle cell nephropathy and
haemostasis, L.W.S.Van Eps and O.C.Leeksma; disseminated intravascular
coagulation and the kidney, P.Kincaid-Smith and J.A.Whitworth. Part 5
Thrombotic microangiopathy and the kidney: the haemolytic uraemic syndrome,
B.S.Kaplan and G.Remuzzi; thrombotic thrombocytopenic purpura - a
disseminated form of thrombotic microangiopathy, E.C.Rossi; haemostasis and
the complications of pregnancy, P.J.Grant and R.M.Prentice; hyperacute renal
allograft rejection, C.L.Pirani and M.A.Hardy. Part 6 Haemostatic defects
associated with dialysis: thrombosis of vascular access for haemodialysis,
F.L.del Greco et al; the use of heparin during haemodialysis, M.B.Donati and
J.Pangrazzi. Part 7 Haemostatic defects indicated by treatments used in renal
disease: thromboembolic complications during cyclosporin A therapy - possible
causes and incidence, N.Perico and G.Remuzzi; plasma exchange, T.H.Price.
