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Handbook of Proteolytic Enzymes 3rd edition [Multiple-component retail product]

Edited by (Senior Scientist, Proteins Department, EMBL-European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire, UK), Edited by (University of Miami, Florida, U.S.A.), Edited by (Wellcome Trust Sanger Institute, Cambridge, U.K.)
  • Formaat: Multiple-component retail product, 4094 pages, kõrgus x laius: 276x216 mm, Contains 5 hardbacks and 1 Digital (delivered electronically) and 1 Paperback / softback and 1 CD-ROM
  • Sari: Handbook of Proteolytic Enzymes, Two-Volume Set with CD-ROM
  • Ilmumisaeg: 03-Dec-2012
  • Kirjastus: Academic Press Inc
  • ISBN-10: 012382219X
  • ISBN-13: 9780123822192
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Handbook of Proteolytic Enzymes 3rd editionSuurem pilt
  • Formaat: Multiple-component retail product, 4094 pages, kõrgus x laius: 276x216 mm, Contains 5 hardbacks and 1 Digital (delivered electronically) and 1 Paperback / softback and 1 CD-ROM
  • Sari: Handbook of Proteolytic Enzymes, Two-Volume Set with CD-ROM
  • Ilmumisaeg: 03-Dec-2012
  • Kirjastus: Academic Press Inc
  • ISBN-10: 012382219X
  • ISBN-13: 9780123822192
Teised raamatud teemal:
Püsilink: https://www.kriso.ee/db/9780123822192.html
Märksõnad:
The third edition of the Handbook of Proteolytic Enzymes is a fully revised and updated major reference work in Elsevier’s canon. For the first time the Handbook will be available as an online via Elsevier’s ScienceDirect platform as well as a three-volume book. The online version will have the enhanced options including online multimedia, cross-referencing capabilities, integrated online delivery and closer integration with the online MEROPS database of peptidases and their inhibitors. This reference work is intended for university libraries, researchers and students, and will be of great interest to the pharmaceutical and biotechnology companies.

The new edition will feature articles on approximately 1000 different proteolytic enzymes written by acknowledged experts in the field. Each article will be a full but concise summary, including details of activity and specificity, structural chemistry, preparation and biological aspects. There are also introductory chapters on peptidase classification and mechanisms and a comprehensive index.
  • Contains over 830 chapters
  • Covers new research in therapeutics and drug trials
  • Supplies content written by experts in the field


Extensively revised and updated, the new edition of the highly regarded Handbook of Proteolytic Enzymes is an essential reference for biochemists, biotechnologists and molecular biologists. Edited by world-renowned experts in the field, this comprehensive work provides detailed information on all known proteolytic enzymes to date. This two-volume set unveils new developments on proteolytic enzymes which are being investigatedin pharmaceutical research for such diseases as HIV, Hepatitis C, and the common cold.

Volume I covers aspartic and metallo petidases while Volume II examines peptidases of cysteine, serine, threonine and unknown catalytic type. A CD-ROM accompanies the book containing fully searchable text, specialised scissile bond searches, 3-D color structures and much more.

* The only comprehensive book on proteolytic enzymes
* Includes 671 chapters, each written by experts in their field, on proteolytic enzymes from all groups of living organisms and the viruses, including those that are currently major targets of pharmaceutical research
* Accompanying CD-ROM provides fully searchable text, 2D structures of peptidases in color and links directly to PubMed and MEROPS databases
*Each chapter describes in detail the enzyme name, its history, activity and specificity, structural chemistry, preparation, biological aspects and distinguishing features
*Over 1000 peptidases included

Arvustused

Praise for the Second Edition: "The clear goal of these volumes is to provide complete coverage of proteases. All known enzymes of this class are described. As a reference, this is a very worthwhile contribution. The goals of this book are well met...The major strength of this book is the comprehensive coverage...An essential reference for scientific research...A very impressive offeringAny investigator with a protease question should start here." --Doodys, 2005

"This handbook would be very useful a reference for a library that serves graduate and post-graduate researchers in molecular biology and related fields." --E-STREAMS, 2005

"A very impressive offering. While many of the chapters are short, they provide essential information as well as appropriate references. Any investigator with a protease question should start here." --Doodys

"The Handbook of Proteolytic Enzymes, Second Edition provides a structured and systematic, up-to-date account of the information about proteolytic enzymes...an indispensable reference for all researchers utilizing such enzymes in areas of organic chemistry, biochemistry, biotechnology and molecular biology." --Carbohydrate Polymers, April 2005

"This handbook would be a very useful reference for a library that serves graduate and post-graduate researchers in molecular biology and related fields. However, the CD-ROM version may be significantly more useful than the print version, especially for workers adept with bioinformatics." --Rafael Garcia, Chemical

Muu info

The one-stop resource for proteolytic enzymes
Aspartic Peptidases
Introduction / Clan AA - Family A1 / Clan AA - Family A2 And Others / Other
Clans of Aspartic Peptidases

Glutamic Peptidases

Asparragine Peptide Lyases

Metallopeptidases
Introduction / Clan MA subclan E - Family M1 / Family M2 / Family M3 /
Families M4,M5 and M9 / Family M13 / Other families in subclan MA(E) / Clan
MA subclan M - Families M10 and M11 / Family M12 subfamily A / Other families
in clan MA / Clan MC / Clan MD / Clan ME / Clan MF / Clan MG / Clan MM / Clan
MO / Clan MP / Clan MH / Other clans of metallopeptidases / Metallopeptidases
not yet assigned to clans

Cysteine Peptidases
Introduction / Clan CA - Family C1 / Other families in clan CA / Clan CD /
Clan CE / Clan PA subclan C / Other clans of cysteine peptidases / Cysteine
peptidases not assigned to families

Serine and Threonine Peptidases
Introduction / Clan PA subclan S - Family S1 / Other families in clan PA(S) /
Clan SB - Family S8 / Family S53 / Clan SC - Family S9 / Other families in
clan SC / Clan SE / Clan SF / Clan SH / Other clans of serine peptidases /
Serine peptidases not assigned to family / Clan PB / Unsequenced serine
peptidases / Peptidases of uncertain catalytic type
Currently Dr. Neil Rawlings is a Senior Scientist in the Proteins Department at the EMBL-European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire, UK. Dr. Rawlings has been an active researcher at the Wellcome Trust Sanger Institute for over twenty years. He is extremely well known in the proteolytic enzyme community for his work curating the MEROPS database, an information resource covering peptidases and the proteins that inhibit them, which is used by expert researchers and students worldwide. Dr. Rawlings has published widely in such peer reviewed journals as Genome Research, BMC Bioinformatics, PloS ONE, Nucleic Acids Research, the Journal of Biological Chemistry, and Science.