Summaries of Chapters e1 to e57 |
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xx | |
Contributors |
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xxv | |
Preface |
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xiiii | |
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PART 1 Introduction to Clinical Medicine |
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1 The Practice of Medicine |
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2 | (7) |
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2 Global Issues in Medicine |
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9 | (10) |
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3 Decision-Making in Clinical Medicine |
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19 | (10) |
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4 Screening and Prevention of Disease |
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29 | (4) |
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5 Principles of Clinical Pharmacology |
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33 | (17) |
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50 | (5) |
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7 Medical Disorders During Pregnancy |
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55 | (7) |
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8 Medical Evaluation of the Surgical Patient |
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62 | (5) |
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9 Palliative and End-of-Life Care |
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67 | (18) |
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10 The Safety and Quality of Health Care |
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85 | (8) |
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e1 Primary Care in Low- and Middle-Income Countries |
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e2 Complementary, Alternative, and Integrative Medicine |
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e3 The Economics of Medical Care |
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e4 Racial and Ethnic Disparities in Health Care |
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e5 Ethical Issues in Clinical Medicine |
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e6 Neoplasia During Pregnancy |
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PART 2 Cardinal Manifestations and Presentation of Diseases |
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11 Pain: Pathophysiology and Management |
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93 | (9) |
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102 | (6) |
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108 | (4) |
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112 | (17) |
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129 | (14) |
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Section 2 Alterations in Body Temperature |
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16 Fever and Hyperthermia |
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143 | (5) |
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148 | (10) |
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e7 Atlas of Rashes Associated With Fever |
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18 Fever of Unknown Origin |
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158 | (7) |
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19 Hypothermia and Frostbite |
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165 | (6) |
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Section 3 Nervous System Dysfunction |
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171 | (7) |
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178 | (3) |
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22 Weakness and Paralysis |
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181 | (5) |
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23 Numbness, Tingling, and Sensory Loss |
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186 | (6) |
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24 Gait and Balance Disorders |
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192 | (4) |
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e8 Video Library of Gait Disorders |
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25 Confusion and Delirium |
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196 | (6) |
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26 Aphasia, Memory Loss, and Other Focal Cerebral Disorders |
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202 | (11) |
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e10 Primary Progressive Aphasia, Memory Loss, and Other Focal Cerebral Disorders |
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Maria Luisa Gorno-Tempini |
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213 | (11) |
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Section 4 Disorders of Eyes, Ears, Nose, and Throat |
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224 | (17) |
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e11 Video Library of Neuro-Ophthalmology |
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29 Disorders of Smell and Taste |
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241 | (7) |
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248 | (7) |
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31 Pharyngitis, Sinusitis, Otitis, and Other Upper Respiratory Tract Infections |
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255 | (12) |
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32 Oral Manifestations of Disease |
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267 | (10) |
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e12 Atlas of Oral Manifestations of Disease |
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Section 5 Alterations in Circulatory and Respiratory Functions |
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277 | (5) |
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282 | (5) |
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287 | (3) |
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290 | (5) |
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e13 Approach to the Patient With a Heart Murmur |
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295 | (2) |
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Section 6 Alterations in Gastrointestinal Function |
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297 | (4) |
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39 Nausea, Vomiting, and Indigestion |
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301 | (7) |
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40 Diarrhea and Constipation |
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308 | (12) |
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41 Gastrointestinal Bleeding |
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320 | (4) |
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324 | (6) |
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43 Abdominal Swelling and Ascites |
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330 | (4) |
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Section 7 Alterations in Renal and Urinary Tract Function |
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44 Azotemia and Urinary Abnormalities |
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334 | (7) |
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e14 Atlas of Urinary Sediments and Renal Biopsies |
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45 Fluid and Electrolyte Disturbances |
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341 | (19) |
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e15 Fluid and Electrolyte Imbalances and Acid-Base Disturbances: Case Examples |
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46 Hypercalcemia and Hypocalcemia |
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360 | (3) |
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47 Acidosis and Alkalosis |
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363 | (11) |
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Section 8 Alterations in Sexual Function and Reproduction |
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374 | (6) |
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49 Hirsutism and Virilization |
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380 | (4) |
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50 Menstrual Disorders and Pelvic Pain |
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384 | (5) |
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Section 9 Alterations in the Skin |
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51 Approach to the Patient With a Skin Disorder |
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389 | (6) |
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52 Eczema, Psoriasis, Cutaneous Infections, Acne, and Other Common Skin Disorders |
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395 | (10) |
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53 Skin Manifestations of Internal Disease |
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405 | (19) |
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54 Immunologically Mediated Skin Diseases |
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424 | (8) |
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55 Cutaneous Drug Reactions |
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432 | (8) |
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56 Photosensitivity and Other Reactions to Light |
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440 | (8) |
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e16 Atlas of Skin Manifestations of Internal Disease |
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Section 10 Hematologic Alterations |
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57 Anemia and Polycythemia |
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448 | (9) |
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58 Bleeding and Thrombosis |
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457 | (8) |
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59 Enlargement of Lymph Nodes and Spleen |
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465 | (7) |
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60 Disorders of Granulocytes and Monocytes |
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472 | (14) |
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e17 Atlas of Hematology and Analysis of Peripheral Blood Smears |
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PART 3 Genes, the Environment, and Disease |
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61 Principles of Human Genetics |
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486 | (23) |
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509 | (10) |
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63 The Practice of Genetics in Clinical Medicine |
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519 | (7) |
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e18 Mitochondrial DNA and Heritable Traits and Diseases |
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526 | (10) |
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e19 Systems Biology in Health and Disease |
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PART 4 Regenerative Medicine |
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536 | (3) |
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66 Hematopoietic Stem Cells |
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539 | (4) |
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67 Applications of Stem Cell Biology in Clinical Medicine |
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543 | (4) |
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68 Gene Therapy in Clinical Medicine |
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547 | (5) |
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552 | (4) |
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70 World Demography of Aging |
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556 | (6) |
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562 | (8) |
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72 Clinical Problems of Aging |
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570 | (18) |
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73 Nutrient Requirements and Dietary Assessment |
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588 | (6) |
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74 Vitamin and Trace Mineral Deficiency and Excess |
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594 | (11) |
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75 Malnutrition and Nutritional Assessment |
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605 | (7) |
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76 Enteral and Parenteral Nutrition Therapy |
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612 | (10) |
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622 | (7) |
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78 Evaluation and Management of Obesity |
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629 | (7) |
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636 | (5) |
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80 Involuntary Weight Loss |
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641 | (5) |
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PART 7 Oncology and Hematology |
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Section 1 Neoplastic Disorders |
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81 Approach to the Patient With Cancer |
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646 | (9) |
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82 Prevention and Early Detection of Cancer |
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655 | (8) |
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663 | (9) |
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84 Cancer Cell Biology and Angiogenesis |
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672 | (17) |
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85 Principles of Cancer Treatment |
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689 | (23) |
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86 Infections in Patients With Cancer |
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712 | (11) |
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723 | (10) |
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733 | (4) |
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737 | (17) |
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754 | (10) |
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91 Gastrointestinal Tract Cancer |
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764 | (13) |
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92 Tumors of the Liver and Biliary Tree |
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777 | (9) |
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786 | (4) |
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94 Bladder and Renal Cell Carcinomas |
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790 | (6) |
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95 Benign and Malignant Diseases of the Prostate |
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796 | (10) |
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806 | (4) |
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97 Gynecologic Malignancies |
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810 | (7) |
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98 Soft Tissue and Bone Sarcomas and Bone Metastases |
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817 | (4) |
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99 Carcinoma of Unknown Primary |
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821 | (5) |
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100 Paraneoplastic Syndromes: Endocrinologic/Hematologic |
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826 | (7) |
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101 Paraneoplastic Neurologic Syndromes |
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833 | (5) |
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102 Late Consequences of Cancer and Its Treatment |
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838 | (6) |
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Section 2 Hematopoietic Disorders |
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103 Iron Deficiency and Other Hypoproliferative Anemias |
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844 | (8) |
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104 Disorders of Hemoglobin |
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852 | (10) |
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105 Megaloblastic Anemias |
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862 | (10) |
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106 Hemolytic Anemias and Anemia Due to Acute Blood Loss |
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872 | (15) |
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107 Aplastic Anemia, Myelodysplasia, and Related Bone Marrow Failure Syndromes |
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887 | (11) |
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108 Polycythemia Vera and Other Myeloproliferative Diseases |
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898 | (7) |
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109 Acute and Chronic Myeloid Leukemia |
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905 | (14) |
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110 Malignancies of Lymphoid Cells |
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919 | (17) |
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e21 Less Common Hematologic Malignancies |
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111 Plasma Cell Disorders |
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936 | (9) |
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945 | (6) |
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113 Transfusion Biology and Therapy |
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951 | (7) |
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114 Hematopoietic Cell Transplantation |
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958 | (7) |
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Section 3 Disorders of Hemostasis |
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115 Disorders of Platelets and Vessel Wall |
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965 | (8) |
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116 Coagulation Disorders |
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973 | (10) |
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117 Arterial and Venous Thrombosis |
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983 | (5) |
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118 Antiplatelet, Anticoagulant, and Fibrinolytic Drugs |
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988 | (19) |
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PART 8 Infectious Diseases |
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Section 1 Basic Considerations in Infectious Diseases |
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119 Introduction to Infectious Diseases: Host---Pathogen Interactions |
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1007 | (6) |
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120 Molecular Mechanisms of Microbial Pathogenesis |
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1013 | (10) |
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121 Approach to the Acutely III Infected Febrile Patient |
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1023 | (8) |
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122 Immunization Principles and Vaccine Use |
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1031 | (11) |
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123 Health Recommendations for International Travel |
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1042 | (10) |
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e22 Laboratory Diagnosis of Infectious Diseases |
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Section 2 Clinical Syndromes: Community-Acquired Infections |
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124 Infective Endocarditis |
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1052 | (12) |
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125 Infections of the Skin, Muscles, and Soft Tissues |
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1064 | (7) |
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1071 | (6) |
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127 Intraabdominal Infections and Abscesses |
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1077 | (7) |
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128 Acute Infectious Diarrheal Diseases and Bacterial Food Poisoning |
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1084 | (7) |
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129 Clostridium difficile Infection, Including Pseudomembranous Colitis |
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1091 | (4) |
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130 Sexually Transmitted Infections: Overview and Clinical Approach |
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1095 | (17) |
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e23 Infectious Complications of Burns |
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e24 Infectious Complications of Bites |
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Section 3 Clinical Syndromes: Health Care---Associated Infections |
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131 Health Care---Associated Infections |
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1112 | (8) |
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132 Infections in Transplant Recipients |
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1120 | (13) |
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Section 4 Approach to Therapy for Bacterial Diseases |
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133 Treatment and Prophylaxis of Bacterial Infections |
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1133 | (18) |
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Section 5 Diseases Caused by Gram-Positive Bacteria |
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134 Pneumococcal Infections |
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1151 | (9) |
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135 Staphylococcal Infections |
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1160 | (11) |
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136 Streptococcal Infections |
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1171 | (9) |
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137 Enterococcal Infections |
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1180 | (8) |
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138 Diphtheria and Other Infections Caused by Corynebacteria and Related Species |
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1188 | (6) |
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139 Listeria monocytogenes Infections |
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1194 | (3) |
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1197 | (3) |
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1200 | (4) |
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142 Gas Gangrene and Other Clostridial Infections |
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1204 | (7) |
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Section 6 Diseases Caused by Gram-Negative Bacteria |
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143 Meningococcal Infections |
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1211 | (9) |
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144 Gonococcal Infections |
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1220 | (8) |
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145 Haemophilus and Moraxella Infections |
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1228 | (5) |
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146 Infections Due to the HACEK Group and Miscellaneous Gram-Negative Bacteria |
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1233 | (3) |
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147 Legionella Infections |
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1236 | (5) |
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148 Pertussis and Other Bordetella Infections |
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1241 | (5) |
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149 Diseases Caused by Gram-Negative Enteric Bacilli |
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1246 | (12) |
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150 Acinetobacter Infections |
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1258 | (3) |
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151 Helicobacter pylori Infections |
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1261 | (5) |
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152 Infections Due to Pseudomonas Species and Related Organisms |
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1266 | (8) |
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1274 | (7) |
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1281 | (5) |
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155 Infections Due to Campylobacter and Related Organisms |
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1286 | (3) |
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156 Cholera and Other Vibrioses |
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1289 | (7) |
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1296 | (5) |
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1301 | (4) |
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159 Plague and Other Yersinia Infections |
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1305 | (9) |
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160 Bartonella Infections, Including Cat-Scratch Disease |
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1314 | (6) |
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1320 | (2) |
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Section 7 Miscellaneous Bacterial Infections |
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1322 | (4) |
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1326 | (5) |
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164 Infections Due to Mixed Anaerobic Organisms |
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1331 | (9) |
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Section 8 Mycobacterial Diseases |
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1340 | (19) |
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1359 | (8) |
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167 Nontuberculous Mycobacterial Infections |
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1367 | (4) |
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168 Antimycobacterial Agents |
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1371 | (9) |
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Section 9 Spirochetal Diseases |
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1380 | (9) |
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170 Endemic Treponematoses |
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1389 | (3) |
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1392 | (5) |
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1397 | (4) |
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1401 | (6) |
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Section 10 Diseases Caused by Rickettsiae, Mycoplasmas, and Chlamydiae |
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1407 | (10) |
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175 Infections Due to Mycoplasmas |
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1417 | (4) |
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176 Chlamydial Infections |
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1421 | (11) |
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Section 11 Viral Diseases: General Considerations |
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1432 | (10) |
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178 Antiviral Chemotherapy, Excluding Antiretroviral Drugs |
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1442 | (11) |
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Section 12 Infections Due to DNA Viruses |
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179 Herpes Simplex Virus Infections |
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1453 | (9) |
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180 Varicella-Zoster Virus Infections |
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1462 | (5) |
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181 Epstein-Barr Virus Infections, Including Infectious Mononucleosis |
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1467 | (4) |
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182 Cytomegalovirus and Human Herpesvirus Types 6, 7, and 8 |
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1471 | (5) |
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183 Molluscum Contagiosum, Monkeypox, and Other Poxvirus Infections |
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1476 | (2) |
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184 Parvovirus Infections |
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1478 | (3) |
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185 Human Papillomavirus Infections |
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1481 | (4) |
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Section 13 Infections Due to DNA and RNA Respiratory Viruses |
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186 Common Viral Respiratory Infections |
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1485 | (8) |
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1493 | (7) |
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Section 14 Infections Due to Human Immunodeficiency Virus and Other Human Retroviruses |
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188 The Human Retroviruses |
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1500 | (6) |
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189 Human Immunodeficiency Virus Disease: AIDS and Related Disorders |
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1506 | (82) |
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Section 15 Infections Due to RNA Viruses |
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190 Viral Gastroenteritis |
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1588 | (5) |
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191 Enteroviruses and Reoviruses |
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1593 | (7) |
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1600 | (5) |
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193 Rubella (German Measles) |
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1605 | (3) |
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1608 | (3) |
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195 Rabies and Other Rhabdovirus Infections |
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1611 | (6) |
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196 Infections Caused by Arthropod- and Rodent-Borne Viruses |
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1617 | (16) |
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197 Ebola and Marburg Viruses |
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1633 | (6) |
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Section 16 Fungal Infections |
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198 Diagnosis and Treatment of Fungal Infections |
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1639 | (3) |
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1642 | (3) |
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1645 | (3) |
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1648 | (2) |
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1650 | (3) |
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1653 | (4) |
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1657 | (6) |
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1663 | (4) |
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206 Superficial Mycoses and Less Common Systemic Mycoses |
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1667 | (6) |
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207 Pneumocystis Infections |
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1673 | (4) |
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Section 17 Protozoal and Helminthic Infections: General Considerations |
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e25 Laboratory Diagnosis of Parasitic Infections |
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208 Agents Used to Treat Parasitic Infections |
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1677 | (6) |
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e26 Pharmacology of Agents Used to Treat Parasitic Infections |
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Section 18 Protozoal Infections |
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209 Amebiasis and Infection With Free-Living Amebas |
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1683 | (5) |
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1688 | (18) |
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1706 | (3) |
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e27 Atlas of Blood Smears of Malaria and Babesiosis |
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1709 | (7) |
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213 Chagas' Disease and Trypanosomiasis |
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1716 | (6) |
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214 Toxoplasma Infections |
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1722 | (7) |
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215 Protozoal Intestinal Infections and Trichomoniasis |
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1729 | (6) |
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Section 19 Helminthic Infections |
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216 Trichinellosis and Other Tissue Nematode Infections |
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1735 | (4) |
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217 Intestinal Nematode Infections |
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1739 | (6) |
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218 Filarial and Related Infections |
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1745 | (7) |
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219 Schistosomiasis and Other Trematode Infections |
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1752 | (7) |
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1759 | (9) |
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PART 9 Terrorism and Clinical Medicine |
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221 Microbial Bioterrorism |
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1768 | (11) |
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1779 | (9) |
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1788 | (10) |
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PART 10 Disorders of the Cardiovascular System |
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Section 1 Introduction to Cardiovascular Disorders |
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224 Basic Biology of the Cardiovascular System |
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1798 | (13) |
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225 Epidemiology of Cardiovascular Disease |
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1811 | (6) |
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226 Approach to the Patient With Possible Cardiovascular Disease |
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1817 | (4) |
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Section 2 Diagnosis of Cardiovascular Disorders |
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227 Physical Examination of the Cardiovascular System |
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1821 | (10) |
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1831 | (9) |
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e28 Atlas of Electrocardiography |
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229 Noninvasive Cardiac Imaging: Echocardiography, Nuclear Cardiology, and MRI/CT Imaging |
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1840 | (13) |
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Pamithaya Chareonthaitawee |
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e29 Atlas of Noninvasive Cardiac Imaging |
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Panithya Chareonthaitawee |
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230 Diagnostic Cardiac Catheterization and Coronary Angiography |
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1853 | (7) |
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Section 3 Disorders of Rhythm |
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231 Principles of Electrophysiology |
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1860 | (7) |
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1867 | (11) |
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1878 | (23) |
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e30 Atlas of Cardiac Arrhythmias |
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Section 4 Disorders of the Heart |
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234 Heart Failure and Cor Pulmonale |
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1901 | (15) |
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235 Cardiac Transplantation and Prolonged Assisted Circulation |
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1916 | (4) |
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236 Congenital Heart Disease in the Adult |
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1920 | (9) |
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237 Valvular Heart Disease |
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1929 | (22) |
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238 Cardiomyopathy and Myocarditis |
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1951 | (20) |
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1971 | (8) |
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240 Tumors and Trauma of the Heart |
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1979 | (4) |
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e31 Cardiac Manifestations of Systemic Disease |
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Section 5 Vascular Disease |
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241 The Pathogenesis, Prevention, and Treatment of Atherosclerosis |
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1983 | (9) |
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e32 Atlas of Atherosclerosis |
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242 The Metabolic Syndrome |
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1992 | (6) |
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243 Ischemic Heart Disease |
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1998 | (17) |
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244 Unstable Angina and Non-ST-Segment Elevation Myocardial Infarction |
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2015 | (6) |
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|
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245 ST-Segment Elevation Myocardial Infarction |
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2021 | (14) |
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246 Percutaneous Coronary Interventions and Other Interventional Procedures |
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2035 | (7) |
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|
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e33 Atlas of Percutaneous Revascularization |
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247 Hypertensive Vascular Disease |
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2042 | (18) |
|
|
248 Diseases of the Aorta |
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2060 | (6) |
|
|
|
249 Vascular Diseases of the Extremities |
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2066 | (10) |
|
|
|
250 Pulmonary Hypertension |
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|
2076 | (8) |
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|
PART 11 Disorders of the Respiratory System |
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Section 1 Diagnosis of Respiratory Disorders |
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|
251 Approach to the Patient With Disease of the Respiratory System |
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2084 | (3) |
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252 Disturbances of Respiratory Function |
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2087 | (7) |
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|
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253 Diagnostic Procedures in Respiratory Disease |
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2094 | (8) |
|
|
|
e34 Atlas of Chest Imaging |
|
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|
Section 2 Diseases of the Respiratory System |
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2102 | (14) |
|
|
255 Hypersensitivity Pneumonitis and Pulmonary Infiltrates With Eosinophilia |
|
|
2116 | (5) |
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|
|
256 Occupational and Environmental Lung Disease |
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|
2121 | (9) |
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|
2130 | (12) |
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|
|
258 Bronchiectasis and Lung Abscess |
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|
2142 | (5) |
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2147 | (4) |
|
|
260 Chronic Obstructive Pulmonary Disease |
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|
2151 | (9) |
|
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|
|
261 Interstitial Lung Diseases |
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|
2160 | (10) |
|
|
262 Deep Venous Thrombosis and Pulmonary Thromboembolism |
|
|
2170 | (8) |
|
|
263 Disorders of the Pleura and Mediastinum |
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|
2178 | (4) |
|
|
264 Disorders of Ventilation |
|
|
2182 | (4) |
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2186 | (3) |
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|
2189 | (7) |
|
|
PART 12 Critical Care Medicine |
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Section 1 Respiratory Critical Care |
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267 Approach to the Patient With Critical Illness |
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|
2196 | (9) |
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|
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268 Acute Respiratory Distress Syndrome |
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|
2205 | (5) |
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|
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269 Mechanical Ventilatory Support |
|
|
2210 | (5) |
|
|
Section 2 Shock and Cardiac Arrest |
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|
|
270 Approach to the Patient With Shock |
|
|
2215 | (8) |
|
|
271 Severe Sepsis and Septic Shock |
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|
2223 | (9) |
|
|
272 Cardiogenic Shock and Pulmonary Edema |
|
|
2232 | (6) |
|
|
|
273 Cardiovascular Collapse, Cardiac Arrest, and Sudden Cardiac Death |
|
|
2238 | (9) |
|
|
|
Section 3 Neurologic Critical Care |
|
|
|
|
2247 | (7) |
|
|
275 Neurologic Critical Care, Including Hypoxic-Ischemic Encephalopathy and Subarachnoid Hemorrhage |
|
|
2254 | (12) |
|
|
|
|
Section 4 Oncologic Emergencies |
|
|
|
276 Oncologic Emergencies |
|
|
2266 | (14) |
|
|
|
PART 13 Disorders of the Kidney and Urinary Tract |
|
|
|
277 Cellular and Molecular Biology of the Kidney |
|
|
2280 | (9) |
|
|
|
278 Adaption of the Kidney to Renal Injury |
|
|
2289 | (4) |
|
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|
2293 | (15) |
|
|
|
280 Chronic Kidney Disease |
|
|
2308 | (14) |
|
|
|
281 Dialysis in the Treatment of Renal Failure |
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|
2322 | (5) |
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|
|
282 Transplantation in the Treatment of Renal Failure |
|
|
2327 | (7) |
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|
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|
|
2334 | (21) |
|
|
|
284 Polycystic Kidney Disease and Other Inherited Tubular Disorders |
|
|
2355 | (12) |
|
|
|
285 Tubulointerstitial Diseases of the Kidney |
|
|
2367 | (8) |
|
|
|
286 Vascular Injury to the Kidney |
|
|
2375 | (7) |
|
|
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|
2382 | (5) |
|
|
|
|
288 Urinary Tract Infections, Pyelonephritis, and Prostatitis |
|
|
2387 | (9) |
|
|
|
e35 Interstitial Cystitis/Painful Bladder Syndrome |
|
|
|
|
289 Urinary Tract Obstruction |
|
|
2396 | (6) |
|
|
PART 14 Disorders of the Gastrointestinal System |
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|
|
Section 1 Disorders of the Alimentary Tract |
|
|
|
290 Approach to the Patient With Gastrointestinal Disease |
|
|
2402 | (7) |
|
|
|
291 Gastrointestinal Endoscopy |
|
|
2409 | (18) |
|
Louis Michel Wong Kee Song |
|
|
|
e36 Video Atlas of Gastrointestinal Endoscopy |
|
|
|
Louis Michel Wong Kee Song |
|
|
|
292 Diseases of the Esophagus |
|
|
2427 | (11) |
|
|
|
293 Peptic Ulcer Disease and Related Disorders |
|
|
2438 | (22) |
|
|
294 Disorders of Absorption |
|
|
2460 | (17) |
|
|
|
|
|
295 Inflammatory Bowel Disease |
|
|
2477 | (19) |
|
|
|
296 Irritable Bowel Syndrome |
|
|
2496 | (6) |
|
|
297 Diverticular Disease and Common Anorectal Disorders |
|
|
2502 | (8) |
|
|
298 Mesenteric Vascular Insufficiency |
|
|
2510 | (3) |
|
|
299 Acute Intestinal Obstruction |
|
|
2513 | (3) |
|
|
300 Acute Appendicitis and Peritonitis |
|
|
2516 | (4) |
|
|
Section 2 Liver and Biliary Tract Disease |
|
|
|
301 Approach to the Patient With Liver Disease |
|
|
2520 | (7) |
|
|
|
302 Evaluation of Liver Function |
|
|
2527 | (4) |
|
|
|
303 The Hyperbilirubinemias |
|
|
2531 | (6) |
|
|
304 Acute Viral Hepatitis |
|
|
2537 | (21) |
|
|
305 Toxic and Drug-Induced Hepatitis |
|
|
2558 | (9) |
|
|
|
2567 | (22) |
|
|
307 Alcoholic Liver Disease |
|
|
2589 | (3) |
|
|
|
308 Cirrhosis and Its Complications |
|
|
2592 | (11) |
|
|
e38 Atlas of Liver Biopsies |
|
|
|
|
|
309 Genetic, Metabolic, and Infiltrative Diseases Affecting the Liver |
|
|
2603 | (3) |
|
|
310 Liver Transplantation |
|
|
2606 | (9) |
|
|
|
311 Diseases of the Gallbladder and Bile Ducts |
|
|
2615 | (14) |
|
|
|
Section 3 Disorders of the Pancreas |
|
|
|
312 Approach to the Patient With Pancreatic Disease |
|
|
2629 | (5) |
|
|
|
|
313 Acute and Chronic Pancreatitis |
|
|
2634 | (16) |
|
|
|
|
|
PART 15 Disorders of the Joints and Adjacent Tissues |
|
|
|
Section 1 The Immune System in Health and Disease |
|
|
|
314 Introduction to the Immune System |
|
|
2650 | (35) |
|
|
|
|
315 The Major Histocompatibility Complex |
|
|
2685 | (10) |
|
|
316 Primary Immune Deficiency Diseases |
|
|
2695 | (12) |
|
|
e39 Primary Immunodeficiencies Associated With (or Secondary to) Other Diseases |
|
|
|
|
Section 2 Disorders of Immune-Mediated Injury |
|
|
|
317 Allergies, Anaphylaxis, and Systemic Mastocytosis |
|
|
2707 | (12) |
|
|
318 Autoimmunity and Autoimmune Diseases |
|
|
2719 | (5) |
|
|
|
319 Systemic Lupus Erythematosus |
|
|
2724 | (12) |
|
|
320 Antiphospholipid Antibody Syndrome |
|
|
2736 | (2) |
|
Haralampos M. Moutsopoulos |
|
|
Panayiotis G. Vlachoyiannopoulos |
|
|
|
2738 | (14) |
|
|
|
322 Acute Rheumatic Fever |
|
|
2752 | (5) |
|
|
323 Systemic Sclerosis (Scleroderma) and Related Disorders |
|
|
2757 | (13) |
|
|
|
2770 | (4) |
|
Haralampos M. Moutsopoulos |
|
|
|
325 The Spondyloarthritides |
|
|
2774 | (11) |
|
|
326 The Vasculitis Syndromes |
|
|
2785 | (16) |
|
|
|
e40 Atlas of the Vasculitic Syndromes |
|
|
|
|
|
|
2801 | (1) |
|
Haralampos M. Moutsopoulos |
|
|
328 Relapsing Polychondritis |
|
|
2802 | (3) |
|
|
|
2805 | (9) |
|
|
|
330 Familial Mediterranean Fever and Other Hereditary Recurrent Fevers |
|
|
2814 | (4) |
|
|
Section 3 Disorders of the Joints and Adjacent Tissues |
|
|
|
331 Approach to Articular and Musculoskeletal Disorders |
|
|
2818 | (10) |
|
|
|
|
2828 | (9) |
|
|
333 Gout and Other Crystal-Associated Arthropathies |
|
|
2837 | (5) |
|
|
|
|
2842 | (7) |
|
|
|
2849 | (3) |
|
|
336 Arthritis Associated With Systemic Disease, and Other Arthritides |
|
|
2852 | (8) |
|
|
|
337 Periarticular Disorders of the Extremities |
|
|
2860 | (6) |
|
|
|
PART 16 Endocrinology and Metabolism |
|
|
|
|
|
338 Principles of Endocrinology |
|
|
2866 | (10) |
|
|
339 Disorders of the Anterior Pituitary and Hypothalamus |
|
|
2876 | (26) |
|
|
|
340 Disorders of the Neurohypophysis |
|
|
2902 | (9) |
|
|
341 Disorders of the Thyroid Gland |
|
|
2911 | (29) |
|
|
|
342 Disorders of the Adrenal Cortex |
|
|
2940 | (22) |
|
|
|
2962 | (6) |
|
|
|
2968 | (35) |
|
|
|
3003 | (7) |
|
|
|
346 Disorders of the Testes and Male Reproductive System |
|
|
3010 | (18) |
|
|
|
347 The Female Reproductive System, Infertility, and Contraception |
|
|
3028 | (12) |
|
|
348 The Menopause Transition and Postmenopausal Hormone Therapy |
|
|
3040 | (6) |
|
|
|
349 Disorders of Sex Development |
|
|
3046 | (10) |
|
|
|
350 Endocrine Tumors of the Gastrointestinal Tract and Pancreas |
|
|
3056 | (16) |
|
|
351 Disorders Affecting Multiple Endocrine Systems |
|
|
3072 | (10) |
|
|
|
Section 2 Disorders of Bone and Mineral Metabolism |
|
|
|
352 Bone and Mineral Metabolism in Health and Disease |
|
|
3082 | (14) |
|
|
|
|
|
353 Disorders of the Parathyroid Gland and Calcium Homeostasis |
|
|
3096 | (24) |
|
|
|
|
3120 | (16) |
|
|
|
355 Paget's Disease and Other Dysplasias of Bone |
|
|
3136 | (9) |
|
|
|
Section 3 Disorders of Intermediary Metabolism |
|
|
|
356 Disorders of Lipoprotein Metabolism |
|
|
3145 | (17) |
|
|
|
|
3162 | (5) |
|
|
|
3167 | (14) |
|
|
|
359 Disorders of Purine and Pyrimidine Metabolism |
|
|
3181 | (7) |
|
|
|
|
3188 | (3) |
|
|
361 Lysosomal Storage Diseases |
|
|
3191 | (7) |
|
|
|
362 Glycogen Storage Diseases and Other Inherited Disorders of Carbohydrate Metabolism |
|
|
3198 | (6) |
|
|
|
363 Heritable Disorders of Connective Tissue |
|
|
3204 | (10) |
|
|
|
364 Inherited Disorders of Amino Acid Metabolism in Adults |
|
|
3214 | (6) |
|
|
365 Inherited Defects of Membrane Transport |
|
|
3220 | (4) |
|
|
e41 Atlas of Clinical Manifestations of Metabolic Diseases |
|
|
|
|
PART 17 Neurologic Disorders |
|
|
|
Section 1 Diagnosis of Neurologic Disorders |
|
|
|
366 Biology of Neurologic Diseases |
|
|
3224 | (9) |
|
|
|
367 Approach to the Patient With Neurologic Disease |
|
|
3233 | (7) |
|
|
|
|
e42 The Neurologic Screening Exam |
|
|
|
|
e43 Video Atlas of the Detailed Neurologic Examination |
|
|
|
|
368 Neuroimaging in Neurologic Disorders |
|
|
3240 | (11) |
|
|
e44 Atlas of Neuroimaging |
|
|
|
|
|
e45 Electrodiagnostic Studies of Nervous System Disorders: EEG, Evoked Potentials, and EMG |
|
|
|
|
e46 Technique of Lumbar Puncture |
|
|
|
|
|
Section 2 Diseases of the Central Nervous System |
|
|
|
369 Seizures and Epilepsy |
|
|
3251 | (19) |
|
|
370 Cerebrovascular Diseases |
|
|
3270 | (30) |
|
|
|
|
|
3300 | (17) |
|
|
|
372 Parkinson's Disease and Other Movement Disorders |
|
|
3317 | (18) |
|
|
|
|
3335 | (10) |
|
|
374 Amyotrophic Lateral Sclerosis and Other Motor Neuron Diseases |
|
|
3345 | (6) |
|
|
375 Disorders of the Autonomic Nervous System |
|
|
3351 | (9) |
|
|
|
376 Trigeminal Neuralgia, Bell's Palsy, and Other Cranial Nerve Disorders |
|
|
3360 | (6) |
|
|
|
377 Diseases of the Spinal Cord |
|
|
3366 | (11) |
|
|
|
378 Concussion and Other Head Injuries |
|
|
3377 | (5) |
|
|
379 Primary and Metastatic Tumors of the Nervous System |
|
|
3382 | (13) |
|
|
|
380 Multiple Sclerosis and Other Demyelinating Diseases |
|
|
3395 | (15) |
|
|
|
381 Meningitis, Encephalitis, Brain Abscess, and Empyema |
|
|
3410 | (25) |
|
|
|
382 Chronic and Recurrent Meningitis |
|
|
3435 | (6) |
|
|
|
|
3441 | (7) |
|
|
|
Section 3 Nerve and Muscle Disorders |
|
|
|
384 Peripheral Neuropathy |
|
|
3448 | (25) |
|
|
|
385 Guillain-Barre Syndrome and Other Immune-Mediated Neuropathies |
|
|
3473 | (7) |
|
|
|
386 Myasthenia Gravis and Other Diseases of the Neuromuscular Junction |
|
|
3480 | (7) |
|
|
387 Muscular Dystrophies and Other Muscle Diseases |
|
|
3487 | (22) |
|
|
|
388 Polymyositis, Dermatomyositis, and Inclusion Body Myositis |
|
|
3509 | (10) |
|
|
e47 Special Issues in Inpatient Neurologic Consultation |
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|
|
|
|
Section 4 Chronic Fatigue Syndrome |
|
|
|
389 Chronic Fatigue Syndrome |
|
|
3519 | (3) |
|
|
|
Section 5 Psychiatric Disorders |
|
|
|
390 Biology of Psychiatric Disorders |
|
|
3522 | (7) |
|
|
|
|
|
3529 | (17) |
|
|
Section 6 Alcoholism and Drug Dependency |
|
|
|
392 Alcohol and Alcoholism |
|
|
3546 | (6) |
|
|
393 Opioid Drug Abuse and Dependence |
|
|
3552 | (4) |
|
|
394 Cocaine and Other Commonly Abused Drugs |
|
|
3556 | (4) |
|
|
|
|
3560 | (6) |
|
|
e48 Neuropsychiatric Illnesses in War Veterans |
|
|
|
|
PART 18 Poisoning, Drug Overdose, and Envenomation |
|
|
|
e49 Heavy Metal Poisoning |
|
|
|
|
e50 Poisoning and Drug Overdosage |
|
|
|
|
396 Disorders Caused by Venomous Snakebites and Marine Animal Exposures |
|
|
3566 | (10) |
|
|
|
397 Ectoparasite Infestations and Arthropod Bites and Stings |
|
|
3576 | (9) |
|
|
PART 19 High-Altitude and Decompression Sickness |
|
|
|
|
|
|
|
e52 Hyperbaric and Diving Medicine |
|
|
|
|
|
Appendix: Laboratory Values of Clinical Importance |
|
|
3585 | (26) |
|
|
|
|
|
e53 The Clinical Laboratory in Modern Health Care |
|
|
|
|
e54 Clinical Procedure Tutorial: Central Venous Catheter Placement |
|
|
|
|
|
|
e55 Clinical Procedure Tutorial: Thoracentesis |
|
|
|
|
|
e56 Clinical Procedure Tutorial: Abdominal Paracentesis |
|
|
|
|
|
|
e57 Clinical Procedure Tutorial: Endotracheal Intubation |
|
|
|
|
Index |
|
3611 | |