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xi | |
| Preface |
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xxvii | |
| Acknowledgments |
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xxix | |
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1 Cardinal manifestations of cancer |
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3 | (4) |
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2 Biological hallmarks of cancer |
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7 | (12) |
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3 Molecular biology, genetics, and translational models of human cancer |
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19 | (30) |
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49 | (24) |
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73 | (16) |
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6 Epigenetic contributions to human cancer |
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89 | (12) |
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7 Cancer genomics and evolution |
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101 | (24) |
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8 Chromosomal aberrations in cancer |
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125 | (18) |
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9 MicroRNA expression in cancer |
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143 | (8) |
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10 Aberrant signaling pathways in cancer |
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151 | (10) |
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11 Differentiation therapy |
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161 | (16) |
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177 | (10) |
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187 | (14) |
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14 Cancer cell immortality: targeting telomerase and telomeres |
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201 | (10) |
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211 | (12) |
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223 | (24) |
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Part 3 QUANTITATIVE ONCOLOGY |
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247 | (14) |
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18 Systems biology and genomics |
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261 | (8) |
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19 Statistical innovations in cancer research |
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269 | (16) |
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20 Biomarker based clinical trial design in the era of genomic medicine |
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285 | (8) |
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21 Clinical and research informatics data strategy for precision oncology |
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293 | (12) |
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22 Chemical carcinogenesis |
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305 | (20) |
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325 | (8) |
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24 Ultraviolet radiation carcinogenesis |
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333 | (6) |
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25 Inflammation and cancer |
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339 | (8) |
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347 | (12) |
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359 | (8) |
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28 Papillomaviruses and cervical neoplasia |
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367 | (6) |
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29 Hepatitis viruses and hepatoma |
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373 | (6) |
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379 | (12) |
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Part 5 EPIDEMIOLOGY, PREVENTION, AND DETECTION |
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391 | (12) |
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32 Hereditary cancer syndromes: risk assessment and genetic counseling |
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403 | (22) |
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33 Behavioral approaches to cancer prevention |
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425 | (8) |
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34 Diet and nutrition in the etiology and prevention of cancer |
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433 | (20) |
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35 Chemoprevention of cancer |
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453 | (20) |
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36 Cancer screening and early detection |
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473 | (20) |
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Part 6 CLINICAL DISCIPLINES |
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37 Clinical cancer genomic diagnostics and modern diagnostic pathology |
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493 | (12) |
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38 Molecular diagnostics in cancer |
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505 | (14) |
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519 | (2) |
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40 Interventional radiology for the cancer patient |
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521 | (10) |
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41 Principles of surgical oncology |
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531 | (12) |
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42 Principles of radiation oncology |
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543 | (10) |
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43 Principles of medical oncology |
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553 | (14) |
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44 Pain and palliative care |
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567 | (10) |
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577 | (8) |
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46 Principles of cancer rehabilitation medicine |
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585 | (8) |
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47 Integrative oncology in cancer care |
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593 | (6) |
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48 Health services research |
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599 | (14) |
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Part 7 INDIVIDUALIZED TREATMENT |
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49 Precision medicine in oncology drug development |
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613 | (18) |
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50 Drug development of small molecule cancer therapeutics in an Academic Cancer Center |
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631 | (10) |
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51 Principles of dose, schedule, and combination therapy |
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641 | (14) |
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52 Pharmacology of small-molecule anticancer agents |
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655 | (12) |
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667 | (12) |
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54 Pyrimidine and purine antimetabolites |
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679 | (14) |
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55 Alkylating agents and platinum antitumor compounds |
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693 | (8) |
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56 DNA topoisomerase targeting drugs |
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701 | (16) |
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57 Microtubule inhibitors |
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717 | (14) |
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58 Drug resistance and its clinical circumvention |
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731 | (8) |
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Part 9 BIOLOGICAL AND GENE THERAPY |
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59 Cytokines, interferons, and hematopoietic growth factors |
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739 | (16) |
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60 Monoclonal antibody and targeted toxin therapy |
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755 | (26) |
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61 Vaccines and immunomodulators |
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781 | (8) |
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62 T cell immunotherapy of cancer |
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789 | (10) |
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799 | (18) |
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817 | (8) |
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825 | (8) |
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66 Hematopoietic cell transplantation |
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833 | (14) |
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Part 10 SPECIAL POPULATIONS |
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67 Principles of pediatric oncology |
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847 | (20) |
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867 | (10) |
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877 | (8) |
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70 Disparities in cancer care |
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885 | (10) |
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71 Neoplasms in people living with human immunodeficiency virus |
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895 | (16) |
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911 | (10) |
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73 Primary neoplasms of the brain in adults |
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921 | (12) |
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74 Neoplasms of the eye and orbit |
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933 | (10) |
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Claudia M. Prospero Ponce |
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75 Neoplasms of the endocrine glands and pituitary neoplasms |
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943 | (6) |
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76 Neoplasms of the thyroid |
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949 | (12) |
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77 Malignant tumors of the adrenal gland |
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961 | (10) |
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78 Tumors of the diffuse neuroendocrine and gastroenteropancreatic system |
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971 | (10) |
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79 Neoplasms of the head and neck |
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981 | (24) |
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1005 | (24) |
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81 Malignant pleural mesothelioma |
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1029 | (14) |
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82 Thymomas and thymic tumors |
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1043 | (12) |
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83 Tumors of the heart and great vessels |
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1055 | (6) |
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Moritz C. Wyler von Ballmoos |
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84 Primary germ cell tumors of the thorax |
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1061 | (4) |
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85 Neoplasms of the esophagus |
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1065 | (18) |
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86 Carcinoma of the stomach |
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1083 | (12) |
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87 Primary neoplasms of the liver |
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1095 | (14) |
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88 Gallbladder and bile duct cancer |
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1109 | (14) |
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89 Neoplasms of the exocrine pancreas |
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1123 | (16) |
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90 Neoplasms of the appendix and peritoneum |
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1139 | (8) |
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91 Carcinoma of the colon and rectum |
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1147 | (22) |
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1169 | (12) |
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1181 | (10) |
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1191 | (10) |
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95 Neoplasms of the prostate |
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1201 | (38) |
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Christopher J. Logothetis |
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96 Tumors of the penis and the urethra |
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1239 | (6) |
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1245 | (16) |
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Michael Hawking Gladell Paner |
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98 Neoplasms of the vulva and vagina |
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1261 | (14) |
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99 Neoplasms of the cervix |
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1275 | (24) |
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1299 | (12) |
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101 Epithelial ovarian, fallopian tube, and peritoneal cancer |
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1311 | (18) |
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102 Nonepithelial ovarian malignancies |
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1329 | (14) |
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103 Molar pregnancy and gestational trophoblastic neoplasia |
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1343 | (8) |
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1351 | (10) |
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105 Neoplasms of the breast |
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1361 | (52) |
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1413 | (24) |
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1437 | (14) |
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1451 | (26) |
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1477 | (24) |
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110 Myelodysplastic syndromes |
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1501 | (16) |
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111 Acute myeloid leukemia in adults: mast cell leukemia and other mast cell neoplasms |
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1517 | (20) |
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112 Chronic myeloid leukemia |
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1537 | (10) |
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113 Acute lymphoblastic leukemia |
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1547 | (12) |
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114 Chronic lymphocytic leukemia |
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1559 | (10) |
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1569 | (10) |
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116 Clonal hematopoiesis in cancer |
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1579 | (8) |
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117 Non-Hodgkin's lymphoma |
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1587 | (16) |
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118 Mycosis fungoides and Sezary syndrome |
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1603 | (8) |
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119 Plasma cell disorders |
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1611 | (22) |
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120 Myeloproliferative disorders |
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1633 | (14) |
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Part 12 MANAGEMENT OF CANCER COMPLICATIONS |
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121 Neoplasms of unknown primary site |
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1647 | (12) |
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1659 | (14) |
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1673 | (10) |
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124 Neurologic complications of cancer |
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1683 | (18) |
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125 Dermatologic complications of cancer chemotherapy |
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1701 | (14) |
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126 Skeletal complications |
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1715 | (14) |
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127 Hematologic complications and blood bank support |
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1729 | (10) |
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128 Coagulation complications of cancer patients |
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1739 | (8) |
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129 Urologic complications related to cancer and its treatment |
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1747 | (10) |
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130 Cardiac complications |
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1757 | (22) |
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131 Respiratory complications |
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1779 | (32) |
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132 Gastrointestinal and hepatic complications in cancer patients |
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1811 | (16) |
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133 Oral complications of cancer and their treatment |
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1827 | (12) |
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134 Gonadal complications |
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1839 | (10) |
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1849 | (6) |
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136 Endocrine complications and paraneoplastic syndromes |
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1855 | (14) |
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137 Infections in patients with cancer |
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1869 | (14) |
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Dimitrios P. Kontoyiannis |
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138 Oncologic emergencies |
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1883 | (24) |
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Part 13 THE FUTURE OF ONCOLOGY |
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139 A vision for twenty-first century healthcare |
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1907 | (8) |
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| Index |
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1915 | |
