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Human Embryology and Developmental Biology 4th Revised edition [Pehme köide]

  • Formaat: Paperback / softback, 560 pages, kõrgus x laius: 276x216 mm, Approx. 430 illustrations (350 in full color), Contains 1 Paperback / softback and 1 Digital online
  • Ilmumisaeg: 01-Dec-2008
  • Kirjastus: Mosby
  • ISBN-10: 0323053858
  • ISBN-13: 9780323053853
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  • Formaat: Paperback / softback, 560 pages, kõrgus x laius: 276x216 mm, Approx. 430 illustrations (350 in full color), Contains 1 Paperback / softback and 1 Digital online
  • Ilmumisaeg: 01-Dec-2008
  • Kirjastus: Mosby
  • ISBN-10: 0323053858
  • ISBN-13: 9780323053853
Teised raamatud teemal:
Carlson (emeritus cell and developmental biology, U. of Michigan-Ann Arbor) had hoped that after the first flush of molecular biology, the flow of new information on mammalian development would crest and slow. He had also hoped that the time allotted to embryology in American medical schools would stop decreasing. Thwarted in both cases, he has chosen to increase the information in his textbook rather than keep it trimmed to fit a receding curriculum. In such areas as gene regulation, interactions, signals, receptors, and signal transduction, he has presented first-level molecular interactions without delving into entire pathways. Among other new or expanded material are the axiation and fixation of asymmetry in early development, the role of retinoids, and the neural crest. Color illustrations appear throughout. Earlier editions were published between 1994 and 2004. Annotation ©2009 Book News, Inc., Portland, OR (booknews.com)

This thoroughly revised 4th edition offers both clear descriptions and explanations of human embryonic development based on all the most up-to-date scientific discoveries and understanding. Particular attention is paid to the fundamental aspects of molecular mechanisms in development, introducing you to major families of important developmental molecules. Clinical aspects of development are covered throughout in boxed sections of text. First-rate illustrations and Student Consult access, including online animations, complete this essential package.

  • Integrates contemporary developmental knowledge with classical embryological understanding.
  • Interprets complex molecular developments, to help you learn how exactly the embryo develops.
  • Presents first-rate clinical photos and clear drawings, to help you to memorize and understand normal and abnormal development.
  • Uses clear sections within the chapter and summaries at the end of each to help you navigate this complex subject.
  • Includes review questions at the end of each chapter to help you assess your knowledge.


  • Provides more coverage of molecular development to help you interpret complex information.
  • Helps you to understand the full 3-D development of the embryo and the shapes of the developing forms using detailed animations on Student Consult.
  • Revises the section on the development of the head, particularly useful for dental students.


Your purchase entitles you to access the web site until the next edition is published, or until the current edition is no longer offered for sale by Elsevier, whichever occurs first. If the next edition is published less than one year after your purchase, you will be entitled to online access for one year from your date of purchase. Elsevier reserves the right to offer a suitable replacement product (such as a downloadable or CD-ROM-based electronic version) should access to the web site be discontinued.
Developmental Tables
Carnegie Stages of Early Human Embryonic Development (Weeks 1-8) xiii
Major Developmental Events during the Fetal Period xiv
PART I Early Development and the Fetal-Maternal Relationship
1(172)
Getting Ready for Pregnancy
3(24)
Gametogenesis
3(13)
Preparation of the Female Reproductive Tract for Pregnancy
16(5)
Hormonal Interaction Involved with Reproduction in Males
21(6)
Transport of Gametes and Fertilization
27(16)
Ovulation and Egg and Sperm Transport
27(4)
Fertilization
31(12)
Cleavage and Implantation
43(22)
Cleavage
43(14)
Embryo Transport and Implantation
57(8)
Molecular Basis for Embryonic Development
65(20)
Fundamental Molecular Processes in Development
65(20)
Transcription Factors
67(5)
Signaling Molecules
72(4)
Receptor Molecules
76(2)
Signal Transduction
78(7)
Formation of Germ Layers and Early Derivatives
85(18)
Two-Germ-Layer Stage
85(2)
Gastrulation and the Three Embryonic Germ Layers
87(6)
Induction of the Nervous System
93(3)
Cell Adhesion Molecules
96(7)
Establishment of the Basic Embryonic Body Plan
103(28)
Development of the Ectodermal Germ Layer
103(6)
Development of the Mesodermal Germ Layer
109(10)
Development of the Endodermal Germ Layer
119(4)
Basic Structure of 4-Week-Old Embryo
123(8)
Placenta and Extraembryonic Membranes
131(22)
Extraembryonic Tissues
131(3)
Chorion and Placenta
134(8)
Placental Physiology
142(6)
Placenta and Membranes in Multiple Pregnancies
148(5)
Developmental Disorders: Causes, Mechanisms, and Patterns
153(20)
General Principles
154(3)
Causes of Malformations
157(9)
Developmental Disturbances Resulting in Malformations
166(7)
PART II Development of the Body Systems
173(334)
Integumentary, Skeletal, and Muscular Systems
175(38)
Integumentary System
175(12)
Skeleton
187(10)
Muscular System
197(16)
Limb Development
213(26)
Initiation of Limb Development
213(1)
Regulative Properties and Axial Determination
214(1)
Outgrowth of Limb Bud
215(5)
Morphogenetic Control of Early Limb Development
220(4)
Development of Limb Tissues
224(15)
Nervous System
239(44)
Establishment of Nervous System
239(1)
Early Shaping of Nervous System
240(1)
Histogenesis Within the Central Nervous System
240(6)
Craniocaudal Pattern Formation and Segmentation
246(5)
Peripheral Nervous System
251(5)
Autonomic Nervous System
256(2)
Later Structural Changes in the Central Nervous System
258(10)
Ventricles, Meninges, and Cerebrospinal Fluid Formation
268(2)
Cranial Nerves
270(2)
Development of Neural Function
272(11)
Neural Crest
283(16)
Origins of Neural Crest
283(1)
Migrations of Neural Crest
284(1)
Differentiation of Neural Crest Cells
284(3)
Major Divisions of Neural Crest
287(12)
Sense Organs
299(26)
Eye
300(15)
Ear
315(10)
Head and Neck
325(36)
Early Development of Head and Neck
325(2)
Establishing the Pattern of the Craniofacial Region
327(3)
Development of Facial Region
330(9)
Formation of the Teeth
339(8)
Development of Pharynx and Its Derivatives
347(14)
Digestive and Respiratory Systems and Body Cavities
361(42)
Digestive System
361(23)
Respiratory System
384(7)
Body Cavities
391(12)
Urogenital System
403(34)
Urinary System
403(13)
Genital System
416(5)
Sexual Duct System
421(8)
External Genitalia
429(8)
Cardiovascular System
437(48)
Development of Blood and the Vascular System
437(16)
Development and Partitioning of Heart
453(12)
Fetal Circulation
465(20)
Fetal Period and Birth
485(22)
Growth and Form of Fetus
485(1)
Fetal Physiology
485(15)
Parturition
500(1)
Adaptations to Postnatal Life
501(1)
Overview
502(5)
Answers to Clinical Vignettes and Review Questions 507(8)
Index 515(27)
Developmentally Important Molecules Mentioned in Text 542