Muutke küpsiste eelistusi

Hydrogen Peroxide and Cell Signaling, Part B, Volume 527 [Kõva köide]

Volume editor (Pharmacology & Pharmaceutical Sciences, School of Pharmacy, University of Southern California, USA), Volume editor (Department of Molecular Pharmacology and Toxicology, School of Pharmaceutical Sciences, University of Southern California, USA)
  • Formaat: Hardback, 376 pages, kõrgus x laius: 229x152 mm, kaal: 720 g
  • Sari: Methods in Enzymology
  • Ilmumisaeg: 21-Aug-2013
  • Kirjastus: Academic Press Inc
  • ISBN-10: 0124058825
  • ISBN-13: 9780124058828
Teised raamatud teemal:
Hydrogen Peroxide and Cell Signaling, Part B, Volume 527Suurem pilt
  • Formaat: Hardback, 376 pages, kõrgus x laius: 229x152 mm, kaal: 720 g
  • Sari: Methods in Enzymology
  • Ilmumisaeg: 21-Aug-2013
  • Kirjastus: Academic Press Inc
  • ISBN-10: 0124058825
  • ISBN-13: 9780124058828
Teised raamatud teemal:
Püsilink: https://www.kriso.ee/db/9780124058828.html
Märksõnad:

This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This is the second of three volumes on hydrogen peroxide and cell signaling, and includes chapters on such topics as the cellular steady-state of H2O2, evaluating peroxiredoxin sensitivity towards inactivation by peroxide substrates, and peroxiredoxins as preferential targets in H2O2-induced signaling.

  • Continues the legacy of this premier serial with quality chapters authored by leaders in the field
  • Covers hydrogen peroxide and cell signaling
  • Contains chapters on such topics as the cellular steady-state of H2O2, evaluating peroxiredoxin sensitivity towards inactivation by peroxide substrates, and peroxiredoxins as preferential targets in H2O2-induced signaling

Muu info

This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This is the second of three volumes on hydrogen peroxide and cell signaling.
Contributors xi
Preface xv
Volumes in Series xvii
Section I H2O2 Metabolism: Determination of a Cellular Steady-State
1 The Cellular Steady-State of H202: Latency Concepts and Gradients
3(18)
H. Susana Marinho
Luisa Cyrne
Enrique Cadenas
Fernando Antunes
1 Introduction
4(5)
2 Experimental Components and Considerations When Measuring the H202 Gradient in S. cerevisiae Cells
9(3)
3 Experimental Components and Considerations When Measuring the H202 Gradient in Mammalian Cell Lines
12(4)
4 Data Handling/Processing
16(1)
5 Summary
17(4)
Acknowledgments
18(1)
References
18(3)
2 Evaluating Peroxiredoxin Sensitivity Toward Inactivation by Peroxide Substrates
21(20)
Kimberly J. Nelson
Derek Parsonage
P. Andrew Karplus
Leslie B. Poole
1 Introduction
22(4)
2 Materials
26(1)
3 Measuring Inactivation Sensitivity by Steady-State NADPH-Linked Assays
27(7)
4 Measuring Inactivation Sensitivity by Multiturnover Cycling with ROOH and DTT Followed by Mass Spectrometry Analysis
34(1)
5 Measuring Inactivation Sensitivity of Prxl/AhpC Prxs Under Single Turnover Conditions Followed by Gel Electrophoresis
35(3)
6 Conclusions/Summary
38(3)
Acknowledgment
39(1)
References
39(2)
3 Peroxiredoxins as Preferential Targets in H202-Induced Signaling
41(24)
Lia M. Randall
Gerardo Ferrer-Sueta
Ana Denicola
1 Introduction
42(1)
2 Reaction of H202 with Cellular Thiols
43(4)
3 H202 Diffusion Versus Reaction with Cellular Thiols
47(2)
4 Sulfenic Acids as Signal Transduction Intermediates
49(2)
5 Prxs as Preferential Targets for H202
51(1)
6 Prxs as Primary H202 Sensors and Transducers
52(1)
7 Prx-Protein Interactions are Needed to Transmit the Signal
52(3)
8 Posttranslational Regulation of Prxs
55(2)
9 Summary
57(8)
Acknowledgments
58(1)
References
58(7)
4 Selenium in the Redox Regulation of the Nrf2 and the Wnt Pathway
65(22)
Regina Brigelius-Flohe
Anna Patricia Kipp
1 Some Historical Background for Introduction
66(2)
2 Selenium Status and Selenoprotein Synthesis
68(1)
3 Selenium Status and the Keap1/Nrf2 System
69(3)
4 Selenium and the Wnt Pathway
72(3)
5 Common Players and Events in Nrf2 and Wnt Signaling
75(3)
6 How Does Selenium Come into Play?
78(9)
References
80(7)
5 Selenoprotein W as Biomarker for the Efficacy of Selenium Compounds to Act as Source for Selenoprotein Biosynthesis
87(26)
Anna Patricia Kipp
Janna Frombach
Stefanie Deubel
Regina Brigelius-Flohe
1 Introduction
88(2)
2 Experimental
90(4)
3 Results
94(8)
4 Discussion
102(6)
5 Conclusions
108(5)
Acknowledgments
109(1)
References
109(4)
6 Peroxiredoxins and Sulfiredoxin at the Crossroads of the NO and H202 Signaling Pathways
113(16)
Kahina Abbas
Sylvie Riquier
Jean-Claude Drapier
1 Introduction
114(2)
2 The Effect of NO on the Level of 2-Cys-Prx Overoxidation
116(6)
3 Detection of Srx
122(1)
4 Comments
123(6)
Acknowledgments
125(1)
References
125(4)
7 Glutathione and γ-Glutamylcysteine in Hydrogen Peroxide Detoxification
129(16)
Ruben Quintana-Cabrera
Juan P. Bolanos
1 Introduction
130(1)
2 Materials
131(1)
3 Previous Considerations
132(1)
4 Procedure with Purified Enzymes and Substrates
133(4)
5 Analysis in Biological Samples
137(3)
6 Further Applications: H202 Produced by NOS
140(1)
7 Conclusions
140(5)
Acknowledgments
141(1)
References
141(4)
8 Peroxiredoxin-6 and NADPH Oxidase Activity
145(24)
Daniel R. Ambruso
1 Introduction
146(3)
2 Experimental Components and Considerations
149(6)
3 Peroxiredoxin Activity of Prdx6
155(2)
4 Effect of Prdx6 on NADPH Oxidase Activity
157(6)
5 Summary
163(6)
References
165(4)
9 Study of the Signaling Function of Sulfiredoxin and Peroxiredoxin III in Isolated Adrenal Gland: Unsuitability of Clonal and Primary Adrenocortical Cells
169(16)
In Sup Kil
Soo Han Bae
Sue Goo Rhee
1 Introduction
170(1)
2 Hyperoxidation of Prxlll by H202 Generated During Corticosterone Synthesis
171(2)
3 Induction of Srx by ACTH
173(1)
4 Unsuitability of Clonal and Primary Adrenocortical Cells for Studies of the Srx-Prxlll Regulatory Pathway
174(2)
5 Adrenal Gland Organ Culture as an In Vitro Model for the Srx-Prxlll Regulatory Pathway
176(3)
6 Concluding Remarks
179(6)
Acknowledgment
179(1)
References
179(6)
Section II H2O2 in the Regulation of Cellular Processes in Plants
10 The Use of HyPer to Examine Spatial and Temporal Changes in H202 in High Light-Exposed Plants
185(18)
Marino Exposito-Rodriguez
Pierre Philippe Laissue
George R. Littlejohn
Nicholas Smirnoff
Philip M. Mullineaux
1 Introduction
186(5)
2 Experimental Procedures
191(5)
3 Pilot Experiments Using HL Stress
196(2)
4 Conclusions
198(5)
Acknowledgments
198(1)
References
198(5)
11 A Simple and Powerful Approach for Isolation of Arabidopsis Mutants with Increased Tolerance to H202-Induced Cell Death
203(18)
Tsanko Gechev
Nikolay Mehterov
Liya Denev
Jacques Hille
1 Introduction
204(2)
2 Generation and Isolation of Mutants More Tolerant to H2O2-Induced Oxidative Stress
206(3)
3 Identification of Mutations in the Genome
209(2)
4 Analysis of the Mutants with Enhanced Tolerance to H202-Induced Oxidative Stress
211(6)
5 Conclusion
217(4)
Acknowledgments
218(1)
References
218(3)
12 Analysis of Environmental Stress in Plants with the Aid of Marker Genes for H202 Responses
221(18)
Ayaka Hieno
Hushna Ara Naznin
Katsunobu Sawaki
Hiroyuki Koyama
Yusaku Sakai
Haruka Ishino
Mitsuro Hyakumachi
Yoshiharu Y. Yamamoto
1 Introduction
222(2)
2 Experimental Materials and Procedures
224(7)
3 Example of Analysis
231(8)
Appendix: Recipes of Stock Solutions, Buffers, and Media
235(1)
References
236(3)
13 The Role of Plant Bax Inhibitor-1 in Suppressing H202-Induced Cell Death
239(18)
Toshiki Ishikawa
Hirofumi Uchimiya
Maki Kawai-Yamada
1 Introduction
240(2)
2 Morphological Changes of Mitochondria Under ROS Stress
242(4)
3 Assay for Inhibitory Effect of BI-1 on ROS Stress-Induced Cell Death Using Heterologous Expression System in Suspension Cultured Cells
246(7)
4 Summary
253(4)
References
253(4)
14 Comparative Analysis of Cyanobacterial and Plant Peroxiredoxins and Their Electron Donors: Peroxidase Activity and Susceptibility to Overoxidation
257(18)
Marika Lindahl
Francisco Javier Cejudo
1 Introduction
258(1)
2 Expression and Purification of Recombinant Prxs and Thioredoxins
259(1)
3 Prx Activity Assays In Vitro
260(4)
4 Peroxide Decomposition in Cyanobacteria In Vivo
264(3)
5 Overoxidation of Plant and Cyanobacterial 2-Cys Prx
267(5)
6 Concluding Remarks
272(3)
References
272(3)
15 Using Hyper as a Molecular Probe to Visualize Hydrogen Peroxide in Living Plant Cells: A Method with Virtually Unlimited Potential in Plant Biology
275(16)
Alejandra Hernandez-Barrera
Carmen Quinto
Eric A. Johnson
Hen-Ming Wu
Alice Y. Cheung
Luis Cardenas
1 Introduction
276(1)
2 NADPH Oxidase in Plant Cells
277(2)
3 Plant Cells Respond to External and Internal Stimuli
279(1)
4 Visualizing Hydrogen Peroxide in Living Plant Cells
280(1)
5 Hyper as a New Genetically Encoded Probe
281(1)
6 Vector Description and Plant Transformation
282(2)
7 Preparation and Sterilization of Modified Petri Dishes for Growing Arabidopsis Plants for Microscopy Analysis
284(1)
8 Seeds Sterilization and Stratification
284(1)
9 Growth Conditions
285(1)
10 Image Acquisition and Processing
286(5)
Acknowledgments
288(1)
References
288(3)
Author Index 291(22)
Subject Index 313
Lester Packer received a PhD in Microbiology and Biochemistry in 1956 from Yale University. In 1961, he joined the University of California at Berkeley serving as Professor of Cell and Molecular Biology until 2000, and then was appointed Adjunct Professor, Pharmacology and Pharmaceutical Sciences, School of Pharmacy at the University of Southern California. Dr Packer received numerous distinctions including three honorary doctoral degrees, several distinguished Professor appointments. He was awarded Chevalier de lOrdre National du Merite (Knight of the French National Order of Merit) and later promoted to the rank of Officier. He served as President of the Society for Free Radical Research International (SFRRI), founder and Honorary President of the Oxygen Club of California. He has edited numerous books and published research; some of the most cited articles have become classics in the field of free radical biology: Dr Packer is a member of many professional societies and editorial boards. His research elucidated - the Antioxidant Network concept. Exogenous lipoic acid was discovered to be one of the most potent natural antioxidants and placed as the ultimate reductant or in the pecking order of the Antioxidant Network” regenerating vitamins C and E and stimulating glutathione synthesis, thereby improving the overall cellular antioxidant defense. The Antioxidant Network is a concept addressing the cells redox status. He established a world-wide network of research programs by supporting and co-organizing conferences on free radical research and redox biology in Asia, Europe, and America. ENRIQUE CADENAS, MD, PhD, received his PhD in biochemistry from the University of Buenos Aires, School of Medicine. He is professor of pharmacology and pharmaceutical sciences at the University of Southern California School of Pharmacy and of biochemistry and molecular biology at the University of Southern California Keck School of Medicine, and doctor honoris causa (medicine) at the University of Linköping, Sweden. Cadenas was president of the Society for Free Radical Research International (SFRRI) and is fellow of the Society for Free Radical Biology & Medicine. He served the scientific community by participating on NIH study sections (2002-2006; chair 2006-2008). His research interests include energy and redox metabolism in brain aging and the coordinated inflammatory-metabolic responses in brain and neurodegenerative diseases.