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Illustrated Toxicology: With Study Questions [Pehme köide]

(Indian Veterinary Research Institute, India)
  • Formaat: Paperback / softback, 630 pages, kõrgus x laius: 235x191 mm, kaal: 1290 g
  • Ilmumisaeg: 06-Apr-2018
  • Kirjastus: Academic Press Inc
  • ISBN-10: 0128132132
  • ISBN-13: 9780128132135
Teised raamatud teemal:
Illustrated Toxicology: With Study QuestionsSuurem pilt
  • Formaat: Paperback / softback, 630 pages, kõrgus x laius: 235x191 mm, kaal: 1290 g
  • Ilmumisaeg: 06-Apr-2018
  • Kirjastus: Academic Press Inc
  • ISBN-10: 0128132132
  • ISBN-13: 9780128132135
Teised raamatud teemal:
Püsilink: https://www.kriso.ee/db/9780128132135.html
Märksõnad:

Illustrated Toxicology: With Study Questions is an essential, practical resource for self-study and guidance catering to a broad spectrum of students. This book covers a range of core toxicological areas, including pesticides, radioactive materials and poisonous plants, also presenting a section on veterinary toxicology. Across 16 chapters, the book presents key concepts with the aid of over 250 detailed, full-color illustrations. Each section is supplemented with practical exercises to support active learning. This combination of clear illustrations and sample testing will help readers gain a deeper understanding of toxicology.

This book is useful for toxicology, pharmacy, medical and veterinary students, and also serves as a refresher for academics and professionals in the field, including clinical pharmacists, forensic toxicologists, environmentalists and veterinarians.

  • Includes comprehensive coverage of key toxicological concepts for study and revision
  • Provides a visual learning aid with over 250 full-color illustrations
  • Enhances understanding and memory retention of core concepts with the use of practical exercises
Disclaimer xv
Preface xvii
Chapter 1 General toxicology
1(66)
1.1 Definitions and Subdisciplines of Toxicology
2(3)
1.2 Types of Toxicants
5(1)
1.3 Toxicity and Toxic Effects
6(2)
1.3.1 Toxicity in Relation to Frequency and Duration of Exposure
7(1)
1.3.2 Toxicity in Relation to Time of Development and Duration of Induced Effects
7(1)
1.4 Other Terms Used in Toxicology
8(2)
1.5 Classification of Toxic Agents
10(3)
1.6 Toxicity Rating
13(1)
1.7 Historical Stalwarts
13(8)
1.8 Factors Affecting Toxicity
21(5)
1.8.1 Host Factors (Factors Related to Subject)
21(2)
1.8.2 Factors Related to Toxicants or Associated With Xenobiotics
23(2)
1.8.3 Environmental Factors
25(1)
1.8.4 Individual or Nonindividual Factors
25(1)
1.9 Natural Laws Concerning Toxicology
26(12)
1.9.1 Time---Effect Relationship
26(1)
1.9.2 Dose---Response Relationship
27(5)
1.9.3 Variables of Dose---Response Curves
32(3)
1.9.4 Interaction With Receptors
35(3)
1.10 Risk Assessment
38(6)
1.10.1 Definitions
38(2)
1.10.2 Preliminary Evaluation of Risk Assessment
40(1)
1.10.3 Basic Elements of Risk Assessment
40(3)
1.10.4 Establishment of an Acceptable RfD
43(1)
1.11 Question and Answer Exercises
44(23)
1.11.1 Short Questions and Answers
44(8)
1.11.2 Multiple Choice Questions
52(8)
1.11.3 Fill in the Blanks
60(2)
1.11.4 True or False Statements
62(1)
1.11.5 Match the Statements
63(1)
Further Reading
64(3)
Chapter 2 Disposition
67(40)
2.1 Absorption
67(4)
2.2 Distribution
71(1)
2.3 Excretion
72(1)
2.4 Biotransformation
72(4)
2.4.1 Metabolizing Enzymes
73(2)
2.4.2 Bioactivation
75(1)
2.4.3 Electrophiles
75(1)
2.5 Toxicokinetics
76(8)
2.5.1 Toxicokinetic Models
78(5)
2.5.2 Flip-Flop Kinetics
83(1)
2.6 Question and Answer Exercises
84(23)
2.6.1 Short Questions and Answers
84(5)
2.6.2 Multiple Choice Questions
89(13)
2.6.3 Fill in the Blanks
102(1)
2.6.4 True or False Statements
103(3)
Further Reading
106(1)
Chapter 3 Mechanism of toxicity
107(24)
3.1 Definitions
107(1)
3.2 Mode of Action
108(1)
3.3 Mechanism of Toxicity
109(4)
3.4 Question and Answer Exercises
113(18)
3.4.1 Short Questions and Answers
113(1)
3.4.2 Multiple Choice Questions
114(13)
3.4.3 True or False Statements
127(1)
3.4.4 Match the Statements
128(1)
Further Reading
129(2)
Chapter 4 Target organ toxicity
131(34)
4.1 Introduction
131(1)
4.2 Definitions
132(1)
4.3 Hepatotoxicity
132(1)
4.4 Nephrotoxicity (Kidney)
133(1)
4.5 Neurotoxicity (Nervous System)
134(1)
4.6 Hematopoietic (Blood) Toxicity
134(1)
4.7 Pulmonary Toxicity
135(1)
4.8 Developmental and Reproductive Toxicity
135(2)
4.9 Dermal Toxicity
137(1)
4.10 Ocular Toxicity
137(1)
4.11 Target Organ Toxicity End Points
138(2)
4.12 Question and Answer Exercises
140(25)
4.12.1 Short Questions and Answers
140(5)
4.12.2 Multiple Choice Questions
145(15)
4.12.3 Fill in the Blanks
160(1)
4.12.4 Match the Statements
161(1)
Further Reading
162(3)
Chapter 5 Pesticides (agrochemicals)
165(30)
5.1 Definitions
165(1)
5.2 Classification of Pesticides
166(1)
5.3 Insecticides
167(14)
5.3.1 Organochlorine
167(2)
5.3.2 OP and CM Compounds
169(8)
5.3.3 Pyrethroids
177(1)
5.3.4 Natural Insecticides
178(1)
5.3.5 Formamidine and Neonicotinoid
179(2)
5.4 Herbicides
181(1)
5.5 Fungicides
182(1)
5.6 Rodenticides
182(1)
5.7 Fumigants
183(1)
5.8 Question and Answer Exercises
183(12)
5.8.1 Short Questions and Answers
183(5)
5.8.2 Multiple Choice Questions
188(2)
5.8.3 Fill in the Blanks
190(4)
Further Reading
194(1)
Chapter 6 Metals and micronutrients
195(30)
6.1 Metals and Micronutrients
195(1)
6.2 Metals
196(14)
6.2.1 Lead
198(3)
6.2.2 Mercury
201(2)
6.2.3 Arsenic
203(4)
6.2.4 Cadmium
207(2)
6.2.5 Aluminum
209(1)
6.3 Micronutrients
210(5)
6.3.1 Copper
210(1)
6.3.2 Iron
210(2)
6.3.3 Cobalt Deficiency
212(1)
6.3.4 Chromium
212(1)
6.3.5 Nickel
212(2)
6.3.6 Molybdenum
214(1)
6.3.7 Zinc Deficiency
214(1)
6.4 Question and Answer Exercises
215(10)
6.4.1 Short Questions and Answers
215(3)
6.4.2 Multiple Choice Questions
218(2)
6.4.3 Fill in the Blanks
220(3)
Further Reading
223(2)
Chapter 7 Nonmetals and micronutrients
225(22)
7.1 Definitions
225(2)
7.2 Phosphorus
227(2)
7.3 Chlorine
229(1)
7.4 Bromine
229(1)
7.5 Iodine
230(1)
7.6 Formaldehyde (Formalin, Methyl Aldehyde, Methylene Oxide)
230(2)
7.7 Selenium Toxicity/Deficiency
232(1)
7.8 Fluoride Toxicity/Deficiency
233(2)
7.9 Manganese Toxicity/Deficiency
235(1)
7.10 Sulfur
236(1)
7.11 Cyanide
236(3)
7.12 Oxalate Poisoning
239(1)
7.13 Question and Answer Exercises
240(7)
7.13.1 Short Questions and Answers
240(3)
7.13.2 Multiple Choice Questions
243(1)
7.13.3 Fill in the Blanks
244(1)
Further Reading
245(2)
Chapter 8 Solvents, vapors, and gases
247(18)
8.1 Solvents
247(5)
8.1.1 Trichloroethylene
250(1)
8.1.2 Carbon Tetrachloride
251(1)
8.1.3 Benzene
251(1)
8.1.4 Toluene
251(1)
8.1.5 Xylenes and Ethylbenzene
252(1)
8.2 Alcohols
252(2)
8.3 Glycols
254(1)
8.4 Petroleum Products
255(1)
8.5 Gases
256(1)
8.6 Vapors
256(1)
8.7 Inhalants
256(3)
8.8 Question and Answer Exercises
259(6)
8.8.1 Short Questions and Answers
259(2)
8.8.2 Multiple Choice Questions
261(1)
8.8.3 Match the Statements
262(1)
Further Reading
263(2)
Chapter 9 Poisonous and venomous organisms
265(20)
9.1 Definitions
265(1)
9.2 Snakes
266(5)
9.3 Venomous Arthropods
271(4)
9.4 Fish Poisoning
275(3)
9.5 Marine Bites and Stings
278(1)
9.6 Mollusks
278(1)
9.7 Question and Answer Exercises
279(6)
9.7.1 Short Questions and Answers
279(1)
9.7.2 Fill in the Blanks
280(3)
9.7.3 Match the Statements
283(1)
Further Reading
284(1)
Chapter 10 Poisonous foods and food poisonings
285(24)
10.1 Definitions
285(1)
10.2 Microbial Toxins
286(2)
10.3 Mycotoxins
288(5)
10.4 Mushroom Toxicity
293(1)
10.5 Algal Intoxication
294(2)
10.6 Question and Answer Exercises
296(13)
10.6.1 Short Questions and Answers
296(2)
10.6.2 Multiple Choice Questions
298(4)
10.6.3 Fill in the Blanks
302(4)
10.6.4 True or False Statements
306(1)
Further Reading
306(3)
Chapter 11 Poisonous plants
309(22)
11.1 Poisonous Plants
309(1)
11.2 Abrus precatorius
310(1)
11.3 Castor (Ricinus communis, Castor Oil Plant)
311(1)
11.4 Croton
312(1)
11.5 Calotropis
313(1)
11.6 Semecarpus anacardium
314(1)
11.7 Capcicum annum
315(1)
11.8 Eucalyptus globus
316(1)
11.9 Colchicum (Colchicum autumnale)
316(1)
11.10 Oleanders
317(1)
11.11 Aconite
318(2)
11.12 Nicotine (Tobacco)
320(2)
11.13 Strychnine
322(1)
11.14 Other Plants
323(1)
11.15 Question and Answer Exercises
324(7)
11.15.1 Short Questions and Answers
324(1)
11.15.2 Multiple Choice Questions
325(2)
11.15.3 Fill in the Blanks
327(2)
Further Reading
329(2)
Chapter 12 Drugs of use, dependence, and abuse
331(26)
12.1 Dependence, Abuse, and Habituation
331(3)
12.2 Psychoactive Drugs
334(1)
12.3 Coca Alkaloids/Cocaine/Coke/Crack
335(3)
12.4 Marijuana, Hashish/Hash, Charas, and Ganja
338(1)
12.5 Lysergic Acid Diethylamide
339(1)
12.6 Peyote
340(1)
12.7 Opium (Afim)
341(1)
12.8 Heroin
342(1)
12.9 Datura
343(2)
12.10 Amphetamines
345(1)
12.11 Carbon Tetrachloride
345(1)
12.12 Aspirin and Paracetamol
345(1)
12.13 Barbiturates
346(1)
12.14 Question and Answer Exercises
346(11)
12.14.1 Short Questions and Answers
346(3)
12.14.2 Multiple Choice Questions
349(7)
Further Reading
356(1)
Chapter 13 Radioactive materials
357(16)
13.1 Definitions
357(2)
13.2 Classification of Radiation by Its Frequency
359(1)
13.3 Types of Radiation
360(4)
13.3.1 Nonionizing Radiation
362(1)
13.3.2 Ionizing Radiation
363(1)
13.4 Hiroshima and Nagasaki Incidences
364(1)
13.5 Health Effects of Radiation
364(1)
13.6 Question and Answer Exercises
365(8)
13.6.1 Short Questions and Answers
365(3)
13.6.2 Multiple Choice Questions
368(2)
13.6.3 Fill in the Blanks
370(1)
Further Reading
371(2)
Chapter 14 Environmental and ecotoxicology
373(54)
14.1 Environmental Toxicology
373(19)
14.1.1 Exposure of Toxicants
377(6)
14.1.2 Major Pollutants
383(9)
14.2 Ecotoxicology
392(3)
14.3 Question and Answer Exercises
395(32)
14.3.1 Short Questions and Answers
395(10)
14.3.2 Multiple Choice Questions
405(13)
14.3.3 Fill in the Blanks
418(3)
14.3.4 True or False Statements
421(4)
Further Reading
425(2)
Chapter 15 Veterinary toxicology
427(92)
15.1 Introduction
428(1)
15.2 Definitions
428(2)
15.3 Poisonous Plants
430(17)
15.3.1 Plants Containing Cyanide/Cyanogenic Plants
430(5)
15.3.2 Plants Producing Lathyrism
435(2)
15.3.3 Plants Producing Thiamine Deficiency/Bracken Fern Poisoning
437(3)
15.3.4 Plants Producing Photosensitization
440(3)
15.3.5 Other Toxic Plants
443(4)
15.4 Nitrate and Nitrite Poisoning
447(3)
15.5 Ammonia Poisoning
450(1)
15.6 Oxalate Poisoning
451(2)
15.7 Metals and Nonmetals
453(11)
15.7.1 Lead Poisoning
453(1)
15.7.2 Copper (Cu) Poisoning
453(2)
15.7.3 Selenium Poisoning
455(4)
15.7.4 Fluoride Poisoning
459(1)
15.7.5 Sulfur Poisoning
460(1)
15.7.6 Molybdenum Poisoning
461(1)
15.7.7 Cobalt Deficiency (Vitamin B12 Deficiency)
461(1)
15.7.8 Manganese Deficiency
462(1)
15.7.9 Salt Poisoning/Deficiency
462(2)
15.8 Pesticide Poisoning
464(1)
15.9 Poisonous Fungi
464(8)
15.9.1 Definitions
465(1)
15.9.2 Aflatoxicoses
465(1)
15.9.3 Facial Eczema
466(1)
15.9.4 Fescue Toxicosis
467(1)
15.9.5 Zearalenone
467(1)
15.9.6 Trichothecenes
468(1)
15.9.7 Ryegrass Staggers
469(1)
15.9.8 Ergotism
470(1)
15.9.9 Degnala Disease
470(2)
15.10 Algal Poisoning
472(1)
15.11 Poisonous and Venomous Organisms
472(2)
15.11.1 Blister Beetle Poisoning
473(1)
15.11.2 Ticks
473(1)
15.12 Microbial Toxins
474(1)
15.13 Residue Toxicology
475(2)
15.14 Question and Answer Exercises
477(42)
15.14.1 Short Questions and Answers
477(5)
15.14.2 Multiple Choice Questions
482(10)
15.14.3 Fill in the Blanks
492(20)
15.14.4 True or False Statements
512(2)
15.14.5 Correct the Statements
514(2)
15.14.6 Match the Statements
516(1)
Further Reading
517(2)
Chapter 16 Clinical toxicology
519(28)
16.1 Definitions
519(1)
16.2 Analytical Toxicology
520(1)
16.3 Clinical Toxicology
520(1)
16.4 Diagnosis
521(2)
16.5 Treatment of Poisoning
523(4)
16.6 Question and Answer Exercises
527(20)
16.6.1 Short Questions and Answers
527(4)
16.6.2 Multiple Choice Questions
531(11)
16.6.3 Fill in the Blanks
542(3)
16.6.4 Match the Statements
545(1)
Further Reading
545(2)
Chapter 17 Brainstorming: Toxicology question bank
547(46)
17.1 Short Questions
548(4)
17.2 Multiple Choice Questions
552(33)
17.3 Fill the Blanks
585(2)
17.4 Match the Statements
587(6)
Further Reading
591(2)
Index 593
PK Gupta obtained his PhD in Toxicology and taught as Visiting Professor at both the University of Tennessee and West Virginia University in the United States before returning to India as Professor of Toxicology at the Indian Veterinary Research Institute. He is currently Director of the Toxicology Consulting Group and President of the Academy of Sciences for Animal Welfare. He has served as advisor to the World Health Organization, consultant to the United Nations Food and Agriculture Organization, and brings more than 50 years of expertise in animal toxicology to the project.