A
must-have resource for all members of the transplant team,
Kidney Transplantation: Principles and Practice, 9th Edition, provides comprehensive, up-to-date information on every aspect of this complex field. Drs. Stuart J. Knechtle and Lorna P. Marson, along with a global team of internationally renowned surgeons and nephrologists, offer
balanced coverage of both surgical techniques and medical considerations related to kidney transplantation. With updates from cover to cover, this core reference delivers the
practical guidance you need to achieve optimal outcomes in both adults and children.
- Offers state-of-the-art coverage of all areas of kidney transplantation such as preservation of kidneys; mechanisms of rejection and the induction of tolerance; techniques of laparoscopic live donor nephrectomy; and immunosuppression.
- Contains up-to-date outcomes data and analysis of the evidence supporting current practice in the field.
- Includes new chapters on xenotransplantation and COVID-19 in renal transplantation.
- Adds new information on normothermic regional perfusion to the discussion of DCD organ donation and ethics of transplantation, and new information on iBox (the first universal algorithm for predicting the risk of kidney transplant loss) to the biomarkers section.
- Provides relevant, up-to-date information on kidney transplant for all members of the transplant team, with practical information on applied science, clinical information, and surgical procedures.
- Features intraoperative videos and hundreds of superb illustrations to help readers visualize key concepts and nuances of renal transplantation.
- Covers each major immunosuppressive drug in individual chapters, and provides a reference list of all randomized trials for convenient access to critical information.
- An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. Additional digital ancillary content may publish up to 6 weeks following the publication date.
New chapter on xenotransplantation. This area is under active clinical investigation now and it seems likely to move forward in the next few years.
- New chapter on future developments, including cell therapies (this could possibly be merged with the xenotranplantation chapter).
- New chapter on defining metrics of success following transplantation.
- New chapter on COVID in renal transplantation.
- Added discussion of normothermic regional perfusion to the discussion of DCD organ donation and ethics of transplantation (this is a new and evolving approach to organ donation).
- Expanded biomarkers section to include information on iBox (The first universal algorithm for predicting the risk of kidney transplant loss).
- Modified History chapter
- Additional intraoperative video clips (about 10-15 new)
- New authorship for select chapters
Arvustused
"...covers a broad range of topics relevant to kidney transplantation in a single, hardcover volume that includes 43 chapters and is just over 800 pages....this series has intended to serve as a comprehensive guide to the field of kidney transplantation. This book continues to fulfill that goal, with comprehensive discussions of all the basic aspects of transplant medicine..... offers a general overview of a broad range of topics and will be useful to anyone caring for transplant patients, especially those without dedicated training in the field such as students, hospitalists, primary care providers, or general nephrologists and surgeons. The broad nature of the topics covered means sacrificing some in-depth discussions, making this more suited for general practitioners than transplant nephrologists or surgeons. The chapters included here are uniformly well-written and include an abundance of useful references and illustrations.... Overall, the flow of chapters within the textbook is logical, and there are no obvious topics overlooked - an excellent, essential resource." Review by Sam Beavin, MD (University of Kentucky College of Medicine), ©Doody's Review Service 2025. Doody's Score: 88, 3 Stars
1. Kidney Transplantation: A History
2. The Immunology of Transplantation
3. Chronic Kidney Failure: Renal Replacement Therapy
4. The Recipient of a Renal Transplant
5. Access for Renal Replacement Therapy
6. Brain Death and Cardiac Death: Donor Criteria and Care of Deceased Donor
7. Medical Evaluation of the Living Donor
8. Donor Nephrectomy
9. Kidney Preservation
10. Histocompatability in Kidney Transplantation
11. Surgical Techniques of Kidney Transplantation
12. Urological Complications After Kidney Transplant and Transplantation Into an Abnormal Bladder
13. Perioperative Care of Patients Undergoing Kidney Transplantation
14. Early Course of the Patient With a Kidney Transplant
15. Azathioprine and Mycophenolates
16. Steroids
17. Calcineurin Inhibitors
18. mTOR Inhibitors: Sirolimus and Everolimus
19. Antilymphocyte Globulin, Monoclonal Antibodies, and Fusion Proteins
20. Other Forms of Immunosuppression
21. Approaches to the Induction of Tolerance
22. Transplantation in the Sensitized Recipient and Across ABO Blood Groups
23. Paired Exchange Programs for Living Donors,
24. Kidney Allocation
25. Pathology of Kidney Transplantation
26. Biomarkers for Posttransplant Allograft Monitoring
27. Chronic Allograft Failure
28. Vascular and Lymphatic Complications After Kidney Transplantation
29. Cardiovascular Disease in Renal Transplantation
30. Infection in Kidney Transplant Recipients
31. Transplantation in a Pandemic: Lessons Learned From COVID-19
32. Liver Disease Among Renal Transplant Recipients
33. Neurological Complications After Kidney Transplantation
34. Cutaneous Disease in Kidney Transplantation Patients
35. Cancer in Kidney Failure and Kidney Transplantation
36. Pancreas and Kidney Transplantation for Diabetic Nephropathy
37. Kidney Transplantation in Children
38. Advancing Kidney Transplantation in Low- and Middle-Income Countries: Challenges and Strategies
39. Results of Kidney Transplantation
40. Psychosocial Aspects of Kidney Transplantation and Living Kidney Donation
41. Ethical and Legal Aspects of Kidney Donation
42. Xenotransplantation
43. Evidence in Transplantation
Stuart Knechtle, M.D. is the William R. Kenan, Jr. Professor of Surgery and Executive Director of the Duke Transplant Center. He trained in surgery at Duke and in transplant surgery at the University of Wisconsin, Madison where he was appointed as the first Ray D. Owen Professor of Transplantation. He moved to Emory University in 2008 as the Carlos and Marguerite Mason Professor of Liver Transplantation. In 2015 he returned to Duke to establish the Duke Transplant Center and serve as its Executive Director. He holds the William R. Kenan, Jr. Chair in Surgery at Duke. His clinical practice includes kidney, pancreas, and liver transplantation. He directs translational research in transplant immunology and currently serves as Principal Investigator of two NIH-funded clinical trials addressing the challenges of antibody-mediated injury of kidney transplants. He has published over 400 peer reviewed papers, over 60 book chapters, edited four textbooks, and serves on several editorial boards including Annals of Surgery. Lorna Marson is Professor of Transplant Surgery at the University of Edinburgh, and Honorary Consultant Surgeon at the Royal Infirmary of Edinburgh. Lorna held a Clinician Scientist Award from the Academy of Medical Sciences/ Health Foundation from 2003-2008, and continues to work in clinically relevant research in renal transplantation, with translation of a novel agent from bench to bedside. Lorna is Past President of the British Transplantation Society, elected Board member of the European Kidney Transplant Association, and Co-Director of the UK Organ Donation and Transplantation Research Network. She is Associate Medical Director for Research and Development, Organ and Tissues Donation and Transplantation, NHS Blood and Transplant.
