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Laccase and Polyphenol Oxidase: Biochemistry and Biotechnological Applications [Pehme köide]

Edited by (School of Chemistry and Bio21 Molecular Science & Biotechnology Institute, The University of Melbourne, Australia)
  • Formaat: Paperback / softback, 304 pages, kõrgus x laius: 235x191 mm, kaal: 640 g
  • Sari: Foundations and Frontiers in Enzymology
  • Ilmumisaeg: 08-Nov-2024
  • Kirjastus: Academic Press Inc
  • ISBN-10: 0443133018
  • ISBN-13: 9780443133015
  • Formaat: Paperback / softback, 304 pages, kõrgus x laius: 235x191 mm, kaal: 640 g
  • Sari: Foundations and Frontiers in Enzymology
  • Ilmumisaeg: 08-Nov-2024
  • Kirjastus: Academic Press Inc
  • ISBN-10: 0443133018
  • ISBN-13: 9780443133015
Laccase and Polyphenol Oxidase: Biochemistry and Biotechnological Applications, a new volume in the Foundations and Frontiers in Enzymology series, provides a thorough discussion of the laccase and polyphenol oxidase enzyme families, which play a key role in the oxidation of phenolic substrates and an important biological function in many organisms. In recent years, significant advances have been made in understanding these enzymes, but few practical resources exist on their fundamental biology, research methods, and applications. Step-by-step instructions and explanation offer clear guidance in replicating key research and application methodologies discussed.

In this book, world experts discuss the biochemistry of laccase and polyphenol oxidases, research methods, and uses across industries, offering a practical overview of these important enzyme classes and empowering researchers to develop their own studies and hone applications. The book deftly connects topics across these intricate enzyme systems, with early chapters on physicochemical properties of PPO and laccase, followed by separate sections on these related enzyme classes’ function in biological and industrial systems, production, purification, active assays, and application areas from food and wine to healthcare, bioremediation, and green and computational chemistry.

Arvustused

"...explores both the physiological roles and commercial application of these distinctive oxidoreductases. This book aims to provide a comprehensive discussion on PPO and laccase, focusing on their structural and biochemical characteristics, such as substrate specificity and reaction mechanisms. Additionally, it explores their potential industrial applications, including their roles in food and wine production as well as bioremediation processes. The editor characterizes this book as a 'guide to readers into these highly connected but intricate enzyme systems and topics,' indicating that its intended audience is students and scientists seeking an introduction to the field." ©Doody's Review Service, 2025, Peter Kennelly, PhD(Virginia Tech)

1. Introduction
2. Structural aspects and physicochemical properties of PPO and laccase Ryan Dixon
3. Functional roles of PPO Fatemeh Khodadadi, Mehdi Kamali
4. Recombinant PPO: Production, purification, and activity assays Yu Li
5. Emerging industrial applications of PPO E. Selvarajan
6. Recent advances in the design of PPO inhibitors Chen Wai Wong
7. Reaction mechanism and redox potential of laccase Nabangshu Sharma
8. Biological functions of laccases
9. Challenges and applications of laccase in bioremediation Wei-Qin Zhuang
10. Immobilization of laccase for industrial wastewater treatment: Current challenges and future Perspectives Hubert Cabana
11. Engineering of laccase through directed evolution and computational chemistry Victor Guallar

Dr. Leung is a Senior Lecturer in Biological Chemistry at the University of Melbourne. Dr. Leung attained his undergraduate and doctorate degrees at the University of Oxford, and began his independent research career at the University of Auckland in 2013. In 2018, he was appointed co-Deputy Director of the Centre for Green Chemistry Science at the University of Auckland. In 2021, Dr. Leung joined the University of Melbourne, where he is now part of the School of Chemistry and Bio21 Molecular Science & Biotechnology Institute.

Dr. Leungs research focuses on the study of enzyme structure, function, and modulation with an aim to help solve some of the worlds most urgent challenges in health and sustainability. One of his main research interests is the study of multi-copper oxidase including polyphenol oxidase (PPO) and laccase.