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Larsen's Human Embryology 6th edition [Pehme köide]

(University of Utah School of Medicine, Salt Lake City, Utah), (University of Utah School of Medicine, Salt Lake City, Utah), (Creighton University School of Medicine, Omaha, Nebraska), (King's College London Dental Institute, London, U)
  • Formaat: Paperback / softback, 560 pages, kõrgus x laius: 276x216 mm, kaal: 1220 g, Approx. 511 illustrations (432 in full color); Illustrations
  • Ilmumisaeg: 23-Feb-2021
  • Kirjastus: Elsevier - Health Sciences Division
  • ISBN-10: 032369604X
  • ISBN-13: 9780323696043
  • Formaat: Paperback / softback, 560 pages, kõrgus x laius: 276x216 mm, kaal: 1220 g, Approx. 511 illustrations (432 in full color); Illustrations
  • Ilmumisaeg: 23-Feb-2021
  • Kirjastus: Elsevier - Health Sciences Division
  • ISBN-10: 032369604X
  • ISBN-13: 9780323696043
**Selected for 2025 Doodys Core Titles® in Anatomy/Embryology**

Offering a well-organized, straightforward approach to a highly complex subject, Larsens Human Embryology, 6th Edition, provides easy-to-read, comprehensive coverage of human embryonic development for todays students. It integrates anatomy and histology with cellular and molecular mechanisms, focusing on both normal development and congenital anomalies. Highly illustrated with superb drawings and photographs, it features a strong clinical focus based on the most up-to-date scientific discoveries and understanding.

Contains new information on gene editing via CRISPr technology, organoids and the study of human disease, transcription factors and signaling pathways, and single cell sequencing Includes clinical scenarios that describe prevention, diagnosis, and treatment of human birth defects and disease Features a superior art program, online animations, and high-quality drawings and photographs throughout-ideal for todays visual learners. · Includes a strong clinical emphasis through the use of Clinical Tasters, Embryology in Practice, and In the Clinic sections Provides additional information on mechanisms of development and research approaches and strategies to establish these mechanisms with In the Research Lab sections Begins each chapter with an overview of main points as well as a graphical summary, with key terms listed in bold type Covers the embryology information that todays medical students need to know for Board exams, clinics, and more, in a readable, straightforward manner Enhanced eBook version included with purchase. Your enhanced eBook allows you to access 50 narrated animations, multiple-choice questions, and all of the text, figures, and references from the book on a variety of devices

Arvustused

The book and online features constitute a very comprehensive learning tool for human embryology. This sixth edition is an excellent update of the fifth. -©Doodys Review Service, 2022, Brian R. MacPherson, PhD (University of Kentucky College of Medicine) Doodys Score: 91 - 4 Stars!

Introduction: Why Study Human Embryology? 1(12)
Periods of Human Embryology
3(2)
Period of Egg and Embryo: Summary of Main Events
5(2)
Phases of Human Embryology
7(2)
Body Axes: Understanding Embryonic Coordinates
9(1)
Want to Learn More?
10(3)
Chapter 1 Gametogenesis, Fertilization, and First Week
13(28)
Primordial Germ Cells
15(1)
Gametogenesis
16(5)
Spermatogenesis
21(2)
Oogenesis
23(2)
Ovulation
25(4)
Menstrual Cycle
29(3)
Fertilization
32(1)
Cleavage
32(3)
End of First Week: Initiating Implantation
35(6)
Chapter 2 Second Week: Becoming Bilaminar and Fully Implanting
41(14)
Becoming Fully Implanted
43(1)
Embryoblast Reorganizes into Epiblast and Hypoblast
44(1)
Development of Amniotic Cavity
44(1)
Development of Yolk Sac and Chorionic Cavity
44(5)
Uteroplacental Circulatory System Begins to Develop During the Second Week
49(6)
Chapter 3 Third Week: Becoming Trilaminar and Establishing Body Axes
55(23)
Overview of Gastrulation: Forming Three Primary Germ Layers and Body Axes
57(5)
Specifics of Gastrulation: Moving Cells to New Locations and Making Organ Rudiments That Undergo Inductive Interactions
62(11)
Formation of Neural Plate
73(2)
Caudal Elongation of Embryo
75(2)
Primary Versus Secondary Body Development
77(1)
Chapter 4 Fourth Week: Forming the Embryo
78(26)
Tube-Within-A-Tube Body Plan Arises Through Body Folding
79(4)
Neurulation: Establishing Neural Tube, Rudiment of Central Nervous System
83(6)
Secondary Neurulation
89(1)
Cranial-Caudal Regionalization of Neural Tube
89(1)
Neural Crest Cells
89(12)
Somite Differentiation: Forming Dermamyotome and Sclerotome
101(3)
Chapter 5 Principles and Mechanisms of Morphogenesis and Dysmorphogenesis
104(25)
Principles of Morphogenesis and Dysmorphogenesis
104(1)
Animal Models
105(3)
Using Animal Models to Predict Human Risk
108(1)
Experimental Techniques
108(8)
Signaling Pathways
116(9)
Embryonic Stem Cells, Organoids, and Cloning
125(4)
Chapter 6 Fetal Development and the Fetus as a Patient
129(21)
During Fetal Period, Embryonic Organ Systems Mature and Fetus Grows
131(1)
Development of Placenta
131(3)
Development of Umbilical Cord
134(1)
Exchange of Substances Between Maternal and Fetal Blood in Placenta
134(4)
Intrauterine Growth Restriction
138(1)
Maternal Diabetes and Obesity
138(1)
Placenta Produces Several Important Hormones
139(1)
Production and Resorption of Amniotic Fluid
139(1)
Twinning
140(1)
Prenatal Diagnosis Assesses Health of Unborn
140(6)
Treating Fetus in Utero
146(2)
Fetal Cord Blood and Stem Cells
148(1)
Preterm Birth
149(1)
Chapter 7 Development of the Skin and Its Derivatives
150(16)
Origin of Epidermis and Dermis of Skin
151(6)
Development of Skin Derivatives
157(9)
Chapter 8 Development of the Musculoskeletal System
166(25)
Tissue Origins and Differentiation of Musculoskeletal System
167(2)
Somites Differentiate into Sclerotome and Dermamyotome
169(3)
Resegmentation of Sclerotomes
172(7)
Myotomes Develop at Segmental Levels
179(2)
Long Bone and Joint Development
181(4)
Development of Limb Muscles
185(6)
Chapter 9 Development of the Central Nervous System
191(37)
Structural Divisions of Nervous System
194(1)
Functional Divisions of Nervous System
194(1)
Primary Brain Vesicles Subdivide to Form Secondary Brain Vesicles
194(2)
Formation of Brain Flexures
196(2)
Cytodifferentiation of Neural Tube
198(1)
Differentiation of Spinal Cord
198(1)
Differentiation of Brain
198(28)
Growth of Brain
226(2)
Chapter 10 Development of the Peripheral Nervous System
228(17)
Structural Divisions of Nervous System
230(1)
Functional Divisions of Nervous System
230(1)
Origin of PNS
231(2)
Development of Trunk PNS
233(8)
Development of Cranial PNS
241(3)
Differences in Preganglionic and Postganglionic Fiber Length Between Parasympathetic and Sympathetic Divisions of Autonomic Nervous System
244(1)
Chapter 11 Development of the Respiratory System and Body Cavities
245(16)
Development of Lungs and Respiratory Tree
246(7)
Partitioning of Coelom and Formation of Diaphragm
253(8)
Chapter 12 Development of the Heart
261(37)
Establishing Cardiac Lineage
263(1)
Formation of Primary Heart Tube
264(7)
Cardiac Looping
271(2)
Formation of Primitive Blood Vessels Associated With the Endocardial Tube
273(1)
Coordinated Remodeling of Heart Tube and Primitive Vasculature Produces Systemic and Pulmonary Circulations
274(1)
Septation of Heart
275(15)
Development of Pacemaker and Conduction System
290(2)
Development of Epicardium and Coronary Vasculature
292(6)
Chapter 13 Development of the Vasculature
298(37)
Formation of Blood and Vasculature Begins Early in Third Week
300(1)
Vasculogenesis and Angiogenesis
300(6)
Arteries Versus Veins
306(2)
Development of Aortic Arch Arteries
308(6)
Dorsal Aorta Develops Ventral, Lateral, and Posterolateral Branches
314(4)
Primitive Embryonic Venous System Is Divided into Vitelline, Umbilical, and Cardinal Systems
318(9)
Development of Lymphatic System
327(1)
Dramatic Changes Occur in Circulatory System at Birth
328(7)
Chapter 14 Development of the Gastrointestinal Tract
335(33)
Body Folding
337(1)
Dorsal Mesentery Initially Suspends Abdominal Gut Tube
337(1)
Three Regions of Primitive Gut
338(1)
Development of Abdominal Foregut
339(5)
Spleen Development
344(2)
Ventral Mesentery Derivatives
346(4)
Midgut Development
350(2)
I Cytodifferentiation of Gut Endodermal Epithelium
352(6)
I Development of Outer Intestinal Wall and Its Innervation
358(3)
Hindgut Development
361(7)
Chapter 15 Development of the Urinary System
368(18)
Three Nephric Systems Arise During Development
368(10)
Relocation of Kidneys
378(2)
Contributions of Hindgut Endoderm to Urinary Tract
380(4)
Development of Suprarenal Gland
384(2)
Chapter 16 Development of the Reproductive System
386(33)
Reproductive System Arises With Urinary System
388(1)
In Presence of Y Chromosome, Male Development Occurs
388(7)
In Absence of Y Chromosome, Female Development Occurs
395(7)
Development of External Genitalia
402(3)
Suspension of Mesonephric-Gonadal Complex Within Abdomen
405(1)
Development of Inguinal Canals
405(1)
Descent of Testes
405(9)
Ovaries Become Suspended in Broad Ligament of Uterus and Are Held High in Abdominal Cavity by Cranial Suspensory Ligaments
414(5)
Chapter 17 Development of the Pharyngeal Apparatus and Face
419(44)
Origin of Skull
421(9)
Development of Pharyngeal Arches
430(10)
Development of Face
440(3)
Development of Nasal and Oral Cavities
443(5)
Development of Sinuses
448(1)
Fate of Pharyngeal Clefts
448(1)
Pharyngeal Arches Give Rise to Tongue
449(2)
Development of Thyroid Gland
451(2)
Development of Pharyngeal Pouches
453(1)
Development of Salivary Glands
454(2)
Development of Teeth
456(7)
Chapter 18 Development of the Ears
463(15)
Ear Consists of Three Individual Components
464(1)
Development of Inner Ear
465(9)
Development of Middle Ear
474(1)
Development of External Ear
475(3)
Chapter 19 Development of the Eyes
478(13)
Eye Originates From Several Embryonic Tissue Layers
479(1)
Development of Optic Cup and Lens
480(8)
Development of Eyelids
488(3)
Chapter 20 Development of the Limbs
491(23)
Epithelial-Mesenchymal Interactions Control Limb Outgrowth
493(4)
Morphogenesis of Limb
497(11)
Tissue Origins of Limb Structures
508(1)
Differentiation of Limb Bones
508(1)
Innervation of Developing Limb
508(6)
Figure Credits 514