Muutke küpsiste eelistusi

Life Extension: Lessons from Drosophila Softcover reprint of the original 1st ed. 2015 [Pehme köide]

  • Formaat: Paperback / softback, 353 pages, kõrgus x laius: 235x155 mm, kaal: 6166 g, 26 Illustrations, color; 23 Illustrations, black and white; VIII, 353 p. 49 illus., 26 illus. in color., 1 Paperback / softback
  • Sari: Healthy Ageing and Longevity 3
  • Ilmumisaeg: 17-Oct-2016
  • Kirjastus: Springer International Publishing AG
  • ISBN-10: 3319382101
  • ISBN-13: 9783319382104
Teised raamatud teemal:
  • Pehme köide
  • Hind: 95,02 €*
  • * hind on lõplik, st. muud allahindlused enam ei rakendu
  • Tavahind: 111,79 €
  • Säästad 15%
  • Raamatu kohalejõudmiseks kirjastusest kulub orienteeruvalt 2-4 nädalat
  • Kogus:
  • Lisa ostukorvi
  • Tasuta tarne
  • Tellimisaeg 2-4 nädalat
  • Lisa soovinimekirja
  • Formaat: Paperback / softback, 353 pages, kõrgus x laius: 235x155 mm, kaal: 6166 g, 26 Illustrations, color; 23 Illustrations, black and white; VIII, 353 p. 49 illus., 26 illus. in color., 1 Paperback / softback
  • Sari: Healthy Ageing and Longevity 3
  • Ilmumisaeg: 17-Oct-2016
  • Kirjastus: Springer International Publishing AG
  • ISBN-10: 3319382101
  • ISBN-13: 9783319382104
Teised raamatud teemal:
?This book looks at aging through research on Drosophila, the fruit fly that is one of the most widely used model organisms in bio gerontology. Work in model organisms can expand the theoretical knowledge of aging: it yields valuable insight into the molecular and cellular processes that underlie aging process, and it can perhaps provide new therapeutic targets for the treatment of age-related disorders in humans.

Drosophila models have been developed for a large variety of aging-related processes and diseases, and this book provides readers with an overview of current research on the use of the Drosophila model to understand the genetic, molecular and physiological mechanisms that underlie the aging process. Themes of health span, life extension and longevity-associated genes emerge in this collation of international research on Drosophila that is of relevance to geriatrics and gerontology, animal genetics and genomics, and biomedicine.

This fascinating, illustrated book will be of interest to a wide audience, ranging from academic researchers to the general reader.

 Preface.- SECTION I: Genetic regulation of longevity.- Mutations and
quantitative genetic variation: lessons from Drosophila.- Modulation of
Drosophila lifespan by neuronal genes.- Life span, stress resistance and
age-dependent transcriptome dynamics in fruit flies with constitutive and
conditional overexpression of GADD45.- Superoxide dismutase over-expression
and the mitochondrial unfolded protein response.- Effect of Wolbachia
infection on aging and longevity-associated genes in Drosophila.- SECTION II:
Drosophila models for aging-associated diseases.- Skeletal muscle homeostasis
and aging.- Drosophila models of cardiac disease.- Genetic modulation of
cardiac functional aging.- Functional links between circadian clocks, redox
state and aging in Drosophila.- Drosophila models in therapeutic drug
discovery.- SECTION III: Life-extending treatments.- Phytochemicals with
lifespan extension effect in Drosophila.- Life extension in Drosophila by
inhibitors of histone deacetylases.- Drosophila healthspan extension using
dietary manipulation.- The effect of the artificial atmosphere on the flies
longevity.- Effects of several mild stresses applied in adults on aging and
longevity.- Life extension via stage-specific drug interventions in
Drosophila.- Index.