Contributors |
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xi | |
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1 Affinity Chromatography |
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1 | (24) |
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1 | (2) |
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1.2 Basic Components of Affinity Chromatography |
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3 | (2) |
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1.3 Bioaffinity Chromatography |
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5 | (1) |
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1.4 Immunoaffinity Chromatography |
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6 | (3) |
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1.5 Dye-Ligand and Biomimetic Affinity Chromatography |
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9 | (2) |
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1.6 Immobilized Metal-Ion Affinity Chromatography |
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11 | (1) |
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1.7 Analytical Affinity Chromatography |
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11 | (3) |
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1.8 Miscellaneous Methods and Newer Developments |
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14 | (11) |
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17 | (1) |
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17 | (8) |
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2 Derivatization in Liquid Chromatography |
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25 | (32) |
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25 | (2) |
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27 | (22) |
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2.3 Postcolumn Reaction Detectors |
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49 | (3) |
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52 | (5) |
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52 | (5) |
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3 Validation of Liquid Chromatographic Methods |
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57 | (18) |
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3.1 Traditional Method Validation |
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58 | (6) |
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3.2 Quality by Design and Analytical Methods |
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64 | (7) |
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71 | (4) |
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72 | (3) |
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4 Liquid Chromatographic Separation of Enantiomers |
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75 | (18) |
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75 | (2) |
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4.2 A Short History of Chiral Separations By Liquid Chromatography |
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77 | (1) |
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4.3 Materials for the Liquid Chromatographic Separation of Enantiomers |
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78 | (4) |
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4.4 Modes of Liquid Chromatographic Separation of Enantiomers |
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82 | (4) |
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4.5 Separation of Enantiomers By Supercritical Fluid Chromatography |
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86 | (1) |
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4.6 Summary and Future Trends |
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87 | (6) |
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88 | (5) |
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5 Liquid Interaction Chromatography of Polymers |
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93 | (38) |
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94 | (1) |
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5.2 Theoretical Aspects of Isocratic Liquid Chromatography of Polymers |
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94 | (4) |
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5.3 Applications of Liquid Chromatography of Polymers |
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98 | (9) |
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5.4 Hyphenated Techniques |
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107 | (14) |
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121 | (10) |
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122 | (9) |
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6 Amino Acid and Bioamine Separations |
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131 | (18) |
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132 | (1) |
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6.2 Direct Separation of Amino Acids and Amines |
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132 | (3) |
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6.3 Indirect Separation of Amino Acids and Amines |
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135 | (6) |
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6.4 Enantioselective Liquid Chromatographic Analysis of Amino Acids |
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141 | (3) |
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144 | (5) |
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145 | (4) |
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7 Protein and Peptide Separations |
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149 | (36) |
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149 | (2) |
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7.2 Methods of Protein Liquid Chromatography |
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151 | (28) |
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179 | (6) |
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180 | (1) |
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180 | (5) |
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8 Glycans and Monosaccharides |
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185 | (18) |
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185 | (1) |
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186 | (2) |
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8.3 Analysis and Characterization of Glycans |
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188 | (8) |
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8.4 Monosaccharide Composition Analysis |
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196 | (5) |
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201 | (2) |
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201 | (2) |
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203 | (46) |
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9.1 Introduction and Contents |
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204 | (1) |
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9.2 Definitions and Classification |
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205 | (1) |
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9.3 Structures and Occurrence |
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206 | (12) |
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9.4 Sample Extraction and Handling |
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218 | (6) |
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9.5 Lipid Analysis by Liquid Chromatography |
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224 | (19) |
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9.6 Conclusions and Future Perspectives |
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243 | (6) |
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244 | (5) |
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249 | (46) |
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10.1 General Drug Screening |
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251 | (4) |
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10.2 Liquid Chromatography-Mass Spectrometry in Forensic Toxicology |
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255 | (13) |
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10.3 Testing for Driving Under the Influence of Drugs Using Oral Fluid |
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268 | (6) |
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10.4 Toxicological Analysis of Hair in the Investigation of Drug Facilitated Crimes |
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274 | (3) |
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277 | (5) |
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282 | (13) |
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283 | (12) |
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11 Compositional Analysis of Foods |
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295 | (24) |
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296 | (2) |
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298 | (3) |
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301 | (5) |
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11.4 Amino Acids, Peptides, and Proteins |
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306 | (1) |
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307 | (2) |
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11.6 Minor Components of Food |
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309 | (2) |
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311 | (3) |
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11.8 Conclusions and Future Trends |
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314 | (5) |
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315 | (1) |
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315 | (4) |
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12 Multiresidue Methods for Pesticides and Related Contaminants in Food |
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319 | (18) |
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319 | (3) |
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322 | (2) |
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12.3 Matrix Effects In LC-MS Analysis |
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324 | (1) |
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325 | (3) |
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328 | (2) |
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12.6 Individual Methods for Specific Compounds |
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330 | (1) |
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12.7 LC-TOF MS in the Field of Pesticide Residue Analysis |
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331 | (6) |
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333 | (4) |
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13 Environmental Analysis: Persistent Organic Pollutants |
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337 | (52) |
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13.1 Polycyclic Aromatic Hydrocarbons |
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341 | (5) |
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13.2 Chlorinated Aromatic Compounds |
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346 | (1) |
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347 | (5) |
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13.4 Brominated Flame Retardants |
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352 | (8) |
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13.5 Perfluoroalkyl Compounds |
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360 | (12) |
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372 | (1) |
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373 | (2) |
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375 | (14) |
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375 | (14) |
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14 Environmental Analysis: Emerging Pollutants |
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389 | (22) |
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390 | (1) |
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391 | (2) |
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14.3 Target Analysis of Specific Contaminant Groups Using LC-MS |
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393 | (10) |
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403 | (8) |
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404 | (7) |
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15 Analysis of Natural Toxins |
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411 | (20) |
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411 | (4) |
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415 | (3) |
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15.3 Lipophilic Marine Toxins |
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418 | (7) |
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15.4 Saxitoxin and Analogs |
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425 | (6) |
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426 | (5) |
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16 Liquid Chromatography in the Pharmaceutical Industry |
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431 | (24) |
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16.1 The Role of Separation Science in Pharmaceutical Drug Development |
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432 | (1) |
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16.2 Increasing Chromatographic Resolution |
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433 | (11) |
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16.3 Chromatographic Method Development: RPLC |
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444 | (11) |
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452 | (1) |
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453 | (2) |
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17 Determination of Veterinary Drug Residues in Foods by Liquid Chromatography-Mass Spectrometry: Basic and Cutting-Edge Applications |
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455 | (22) |
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456 | (3) |
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17.2 Options in Veterinary Residue Analysis using LC-MS |
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459 | (12) |
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471 | (6) |
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472 | (5) |
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18 Analysis of Vitamins by Liquid Chromatography |
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477 | (42) |
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478 | (1) |
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18.2 Liquid Chromatographic Determination of Water-Soluble Vitamins |
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479 | (10) |
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18.3 Liquid Chromatographic Determination of Fat-Soluble Vitamins |
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489 | (8) |
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18.4 Multivitamin Methods |
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497 | (22) |
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510 | (9) |
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19 Applications of Liquid Chromatography in the Quality Control of Traditional Chinese Medicines, an Overview |
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519 | (22) |
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520 | (1) |
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19.2 Liquid Chromatographic Analysis of Traditional Chinese Medicines |
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520 | (15) |
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535 | (6) |
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536 | (1) |
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537 | (4) |
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20 Analysis of Neurotransmitters and Their Metabolites by Liquid Chromatography |
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541 | (70) |
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542 | (14) |
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556 | (12) |
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568 | (5) |
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573 | (6) |
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20.5 Purines: Adenosine Triphosphate and Adenosine |
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579 | (3) |
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582 | (3) |
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585 | (5) |
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20.8 Multianalyte Monitoring of Neurotransmitters from Diverse Classes |
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590 | (2) |
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20.9 Clinical Applications of Microdialysis Sampling and Liquid Chromatographic-Based Analysis |
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592 | (4) |
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596 | (15) |
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596 | (15) |
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21 Clinical Chemistry, Including Therapeutic Drug Monitoring and Biomarkers for Diagnosis |
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611 | (22) |
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612 | (1) |
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21.2 Preanalytical Specimen Handling in Clinical Liquid Chromatography |
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613 | (1) |
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21.3 Separation Technologies in Clinical Liquid Chromatography |
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613 | (4) |
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21.4 Detection Technologies in Clinical Liquid Chromatography |
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617 | (3) |
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620 | (8) |
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628 | (5) |
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628 | (5) |
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22 Speciation and Element-Specific Detection |
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633 | (18) |
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634 | (1) |
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635 | (1) |
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22.3 Sample Storage and Processing |
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636 | (1) |
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22.4 Speciation Approaches: Direct Methods or Hyphenated Techniques |
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637 | (4) |
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22.5 Interfacing: Nebulizers, Use of Internal Standard and Postcolumn Dilution |
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641 | (2) |
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22.6 Element-Selective Detection |
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643 | (3) |
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22.7 Quantification and Quality Control |
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646 | (5) |
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648 | (3) |
Index |
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651 | |