Lung transplantation is accepted standard of therapy for selected patients with end-stage lung disease. Significant advances have been achieved in the past decade in areas such as donor allocation; organ preservation and management; recipient selection, management and support; surgical and critical care techniques; immune suppression; and infection prophylaxis. This book provides a comprehensive overview of the latest advances in lung transplant relevant not only to the specialist but to other healthcare providers who may refer or care for patients before and after transplantation.
With 38 chapters from international experts in the field, Lung Transplantation: Principles and Practice details current practice in donor and recipient management as well as current treatment strategies and outcomes. Specific instances of pulmonary disease that commonly necessitate lung transplantation are included. The book concludes with a discussion of future direction of therapies for advanced lung disease that are likely to influence transplant practice.
Generously illustrated in full color, this book will be a valuable source of up-to-date information for all surgeons, physicians and critical care specialists involved with lung transplantation, as well as the wider transplant team of immunologists, pathologists, nurses, and donor and transplant coordinators.
Arvustused
"This thorough review of lung transplantation covers in detail all aspects, providing an excellent resource for all health professionals involved in this field. The accompanying ebook can be accessed using different platforms (PC, iPad, Kindle, etc.) and provides tools to easily find chapters, figures, and references This is one of the most complete resources on lung transplantation and it provides a wealth of information that is easy to access via the online version." - Reinaldo Rampolla, MD(Ochsner Medical Center), Doody's Book Review Service
| Preface |
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ix | |
| Acknowledgments |
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xi | |
| Contributors |
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xiii | |
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1 | (1) |
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1 History of lung transplantation |
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3 | (10) |
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2 Immunology of lung transplantation |
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13 | (10) |
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3 Ethical considerations in transplantation: A focus on lung transplantation |
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23 | (6) |
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4 Indications for lung transplantation and patient selection |
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29 | (26) |
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5 Recipient management before transplantation |
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55 | |
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2 | (401) |
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6 Allocation of donor lungs |
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67 | (8) |
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7 Donor selection and management |
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75 | (14) |
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8 Non-heart-beating donors |
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89 | (8) |
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Jose Luis Campo Canaveral de la Cruz |
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9 Donor lung preservation |
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97 | (8) |
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105 | (6) |
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11 Ex vivo lung perfusion |
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111 | (10) |
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PART 3 RECIPIENT MANAGEMENT AND OUTCOME |
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22 The humoral response to lung transplantation |
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121 | (12) |
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13 Anesthesia for lung transplantation |
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133 | (6) |
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14 Mechanical ventilation and extracorporeal membrane oxygenation (ECMO): Bridges to lung transplantation |
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139 | (6) |
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15 Single-lung transplantation: Technical aspects |
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145 | (6) |
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16 Bilateral sequential lung transplantation: Technical aspects |
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151 | (8) |
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17 Heart-lung transplantation: Technical aspects |
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159 | (6) |
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18 Lobar lung transplantation from living donors |
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165 | (10) |
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19 Technical aspects of redo lung transplantation and lung transplantation after previous thoracotomy |
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175 | (8) |
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20 Lung transplantation for idiopathic pulmonary fibrosis |
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183 | (8) |
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21 Lung transplantation for emphysema and σ1,-antitrypsin deficiency |
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191 | (12) |
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22 Lung transplantation for cystic fibrosis and bronchiectasis |
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203 | (10) |
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23 Lung transplantation for pulmonary hypertension |
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213 | (10) |
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24 Lung transplantation for connective tissue disorders |
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223 | (6) |
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25 Posttransplantation critical care management |
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229 | (22) |
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26 Primary graft dysfunction |
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251 | (14) |
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27 Management of surgical complications |
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265 | (14) |
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28 Immunosuppression strategies in lung transplantation |
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279 | (14) |
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29 Viral infections in lung transplantation |
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293 | (14) |
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30 Fungal infections in lung transplantation |
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307 | (14) |
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31 Bacterial infections after lung transplantation |
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321 | (14) |
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32 Diagnosis of lung rejection and infection: A pathologist's perspective |
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335 | (10) |
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Vijayalakshmi Ananthanarayanan |
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33 Obliterative bronchiolitis/bronchiolitis obliterans syndrome: Etiology, diagnosis, and management |
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345 | (14) |
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34 Chronic lung allograft dysfunction other than bronchiolitis obliterans syndrome |
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359 | (12) |
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35 Medical complications of lung transplantation |
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371 | (14) |
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36 Malignancy following lung transplantation |
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385 | (10) |
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37 Quality of life following lung transplantation |
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395 | (8) |
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PART 4 FUTURE OF LUNG TRANSPLANTATION |
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403 | (18) |
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38 Future therapies in lung transplantation |
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403 | (10) |
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39 New horizons in lung transplantation |
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413 | (8) |
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| Index |
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421 | |
Edited by
Wickii T. Vigneswaran, MD, MBA, FRCSC, FRCS(CTh), FACS, professor and chief of thoracic surgery, Loyola University Medical Center and Stritch School of Medicine, Chicago (Maywood), Illinois, USA
Edward R. Garrity, Jr., MD, MBA, professor of medicine, vice chair of clinical operations, and associate director of transplantation services, University of Chicago, Illinois, USA
John A. Odell, MBChB, FRCS(Ed), FACS, emeritus professor of surgery, Mayo Clinic, Jacksonville, Florida, USA