Preface |
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xix | |
Part I Concepts, Principles, and Applications |
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1 | (196) |
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Chapter 1 An Introduction to Managerial Epidemiology |
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3 | (16) |
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Case Study 1.1. Group Health East |
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7 | (11) |
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18 | (1) |
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Chapter 2 Infectious Disease Epidemiology |
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19 | (30) |
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Agent, Host, and Environment |
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20 | (4) |
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24 | (4) |
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28 | (5) |
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Case Study 2.1. Food Poisoning Outbreak at Bluegrass Hospital |
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31 | (2) |
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33 | (8) |
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Case Study 2.2. Outbreak of Influenza in a New York Nursing Home |
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39 | (2) |
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41 | (1) |
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End-of-Chapter Case Exercises |
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42 | (1) |
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43 | (6) |
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Chapter 3 Measuring and Interpreting Morbidity |
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49 | (26) |
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49 | (1) |
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The Nature and Definition of Disease |
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50 | (1) |
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Natural History of Disease |
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51 | (2) |
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Sources of Morbidity Data |
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53 | (1) |
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54 | (5) |
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Case Study 3.1. Product Lines for Group Health East |
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57 | (2) |
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59 | (11) |
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Case Study 3.2. Breast Cancer Screening |
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62 | (4) |
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Case Study 3.3. Prostate Cancer Screening |
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66 | (4) |
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70 | (1) |
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End-of-Chapter Case Exercises |
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70 | (2) |
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72 | (3) |
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Chapter 4 Healthcare Planning and Needs Assessment |
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75 | (32) |
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Community Health Planning Tools and Benchmarks |
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78 | (8) |
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Case Study 4.1. Eastern Kentucky Health |
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84 | (2) |
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86 | (6) |
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Case Study 4.2. Determining Bed Demand for Cardiac Patients Age 65-84 |
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88 | (4) |
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A Strategic Planning Model |
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92 | (2) |
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94 | (2) |
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96 | (2) |
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98 | (3) |
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101 | (1) |
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End-of-Chapter Case Exercises |
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102 | (1) |
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103 | (4) |
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Chapter 5 Quality of Care Measurement |
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107 | (30) |
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109 | (2) |
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111 | (4) |
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Case Study 5.1. MRSA Surveillance at University Hospital |
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113 | (2) |
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Outcomes of Care—Complication Rates |
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115 | (5) |
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Case Study 5.2. Risk-Adjusted Complication Rates in a Small Rural Hospital |
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118 | (2) |
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120 | (1) |
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Avoidable Hospitalizations |
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120 | (2) |
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122 | (5) |
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Case Study 5.3. Inpatient Quality of Care Indicators for Bluegrass Hospital |
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124 | (3) |
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127 | (5) |
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132 | (1) |
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End-of-Chapter Case Exercises |
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133 | (1) |
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134 | (3) |
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Chapter 6 Mortality and Risk Adjustment |
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137 | (34) |
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Measuring Mortality with Rates |
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139 | (1) |
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Comparing Mortality Across Time, Place, and Person |
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140 | (10) |
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Case Study 6.1. Breast Cancer Mortality Rates and Migration |
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147 | (3) |
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Standardization of Mortality Rates |
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150 | (5) |
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Case Study 6.2. Age and Gender Adjustment in Two Managed Care Organizations |
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152 | (3) |
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Risk-Adjusted Mortality Rates |
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155 | (10) |
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Case Study 6.3. Risk Adjustment with Contingency Tables—State of Pennsylvania |
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160 | (3) |
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Case Study 6.4. Risk Adjustment with Multivariate Techniques—State of New York |
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163 | (2) |
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165 | (1) |
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End-of-Chapter Case Exercises |
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166 | (3) |
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169 | (2) |
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Chapter 7 Descriptive Epidemiology: Person, Place, Time |
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171 | (26) |
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Descriptive Epidemiology: The Person |
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171 | (8) |
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Case Study 7.1. Infant Mortality Disparities by Race |
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175 | (4) |
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Descriptive Epidemiology: Place |
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179 | (1) |
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179 | (2) |
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181 | (1) |
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Geographic Information Systems |
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182 | (8) |
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Case Study 7.2. HIV Clinics in Kentucky |
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187 | (3) |
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Descriptive Epidemiology: Time |
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190 | (2) |
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192 | (1) |
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End-of-Chapter Case Exercises |
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193 | (2) |
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195 | (2) |
Part II Epidemiology and Finance |
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197 | (64) |
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Chapter 8 Epidemiology and Financial Management |
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199 | (32) |
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Healthcare Delivery: Reactive or Proactive? |
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199 | (2) |
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201 | (2) |
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The Role of Epidemiology in Finance |
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203 | (2) |
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Capitation: An Introduction |
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205 | (3) |
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208 | (2) |
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Risk Adjustment: The Basics |
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210 | (7) |
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Case Study 8.1. Incorporating Health Risks into Capitation Rates |
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214 | (3) |
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Adjusting Capitation Rates |
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217 | (7) |
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Case Study 8.2. Group Health East: Risk Factors and Capitation Rates |
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220 | (4) |
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224 | (1) |
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225 | (2) |
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227 | (1) |
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End-of-Chapter Case Exercises |
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227 | (1) |
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228 | (3) |
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Chapter 9 Cost-Effectiveness Analysis |
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231 | (30) |
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Cost-Effectiveness Ratios |
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232 | (1) |
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232 | (1) |
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233 | (1) |
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234 | (1) |
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Quality-Adjusted Life Years |
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235 | (4) |
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Case Study 9.1. The Oregon Medicaid Prioritization of Health Services Program |
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238 | (1) |
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239 | (1) |
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240 | (4) |
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244 | (1) |
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245 | (2) |
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247 | (4) |
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Case Study 9.2. Cost-Effectiveness of Health Insurance |
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248 | (3) |
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251 | (6) |
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Case Study 9.3. CEA for Targeted or Universal Prostate Cancer Testing |
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252 | (5) |
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End-of-Chapter Case Exercises |
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257 | (2) |
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259 | (2) |
Part III Evidence-Based Management And Medicine |
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261 | (150) |
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Chapter 10 Statistical Tools |
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265 | (18) |
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Descriptive and Analytical Epidemiology |
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265 | (1) |
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266 | (1) |
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266 | (1) |
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Descriptive Statistics for Continuous Variables |
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267 | (4) |
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Descriptive Statistics for Categorical Variables |
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271 | (1) |
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272 | (5) |
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z Test for Differences in Proportions |
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277 | (1) |
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278 | (2) |
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280 | (1) |
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281 | (1) |
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End-of-Chapter Case Exercises |
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281 | (1) |
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282 | (1) |
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282 | (1) |
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Chapter 11 Case—Control Studies |
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283 | (30) |
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Selection of Cases and Controls |
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284 | (1) |
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285 | (1) |
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Relative Risk in a Case—Control Study |
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286 | (2) |
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288 | (4) |
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Case Study 11.1. Coffee and Pancreatic Cancer |
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292 | (1) |
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292 | (13) |
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Case Study 11.2. Smoking and Low Birth Weight Newborns |
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299 | (4) |
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Case Study 11.3. Fen-Phen and Primary Pulmonary Hypertension |
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303 | (2) |
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305 | (1) |
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Case—Control Advantages and Disadvantages |
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306 | (1) |
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307 | (1) |
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End-of-Chapter Case Exercises |
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307 | (2) |
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309 | (4) |
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Chapter 12 Cohort Studies |
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313 | (28) |
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316 | (1) |
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317 | (4) |
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Relative Risk in a Cohort Study |
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321 | (2) |
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Case Study 12.1. Scottish Heart Study |
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322 | (1) |
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Measures of Disease Burden |
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323 | (3) |
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Case Study 12.2. The Unknown Cohort Study |
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324 | (2) |
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326 | (5) |
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Case Study 12.3. Smoking, Heart Disease, and Lung Cancer |
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328 | (3) |
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Case—Control and Cohort Studies |
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331 | (3) |
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Case Study 12.4. Smoking and Prostate Cancer |
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333 | (1) |
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334 | (1) |
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Advantages and Disadvantages |
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335 | (1) |
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335 | (1) |
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End-of-Chapter Case Exercises |
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336 | (2) |
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338 | (3) |
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Chapter 13 Randomized Clinical Trials |
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341 | (32) |
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343 | (2) |
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Historical Controls and Crossover Studies |
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345 | (1) |
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Methods of Randomized Clinical Trials |
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346 | (1) |
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346 | (3) |
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349 | (1) |
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Integrity of the Randomization |
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350 | (3) |
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353 | (3) |
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Case Study 13.1. The RAND Health Insurance Experiment |
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354 | (2) |
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356 | (6) |
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Case Study 13.2. Vitamin E and n-3 Polyunsaturated Fatty Acids After Myocardial Infarction |
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357 | (4) |
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Case Study 13.3. Inpatient Staffing at Henry Ford Hospital |
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361 | (1) |
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362 | (2) |
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Community Trials, Cluster Randomization, and Ecological Studies |
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364 | (2) |
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366 | (1) |
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End-of-Chapter Case Exercises |
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367 | (2) |
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369 | (4) |
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Chapter 14 Clinical Epidemiology and Decision Making |
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373 | (38) |
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Experience and Tradition in Medical Practice |
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374 | (1) |
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The Evidence Base of Clinical Practice |
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375 | (5) |
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380 | (7) |
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Clinical-Encounter Vignette Part I: Making a Diagnosis for a Patient Presenting with Chest Pain |
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381 | (4) |
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Clinical-Encounter Vignette Part II: Treatment Options for a Patient Diagnosed with GERD |
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385 | (2) |
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387 | (5) |
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Clinical-Encounter Vignette Part III: Prevention and Control Strategies |
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389 | (3) |
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Cost-Effectiveness and the Number Needed to Treat |
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392 | (2) |
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Clinical-Encounter Vignette Part IV: Family History and Number Needed to Treat |
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393 | (1) |
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394 | (11) |
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Case Study 14.1. Clinical Decision-Making Toolbox |
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397 | (8) |
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End-of-Chapter Case Exercises |
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405 | (2) |
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407 | (4) |
Part IV Applications of Epidemiology to Specific Diseases |
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411 | (122) |
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Chapter 15 Cardiovascular Disease |
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413 | (32) |
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414 | (1) |
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415 | (3) |
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The Geographic Distribution of CVD |
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418 | (3) |
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The Biology of CVD and Risk Factors |
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421 | (3) |
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Managerial and Economic Considerations with Screening |
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424 | (7) |
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Case Study 15.1. Screening for CAC |
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427 | (4) |
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Other Considerations for Screening Tests |
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431 | (1) |
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Cost-Effectiveness of CAC Screening |
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432 | (5) |
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Case Study 15.2. Cost-Effectiveness of Gastric Bypass for Severe Obesity |
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433 | (4) |
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Strategies for the Prevention of CVD |
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437 | (1) |
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438 | (1) |
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439 | (1) |
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End-of-Chapter Case Exercises |
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439 | (1) |
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440 | (5) |
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Chapter 16 Human Immunodeficiency Virus Infection |
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445 | (22) |
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Kathleen McDavid Harrison |
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446 | (2) |
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448 | (2) |
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450 | (1) |
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Screening and Diagnostic Tests |
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451 | (4) |
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Case Study 16.1. HIV-1 Enzyme Immunoassay for HIV |
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452 | (3) |
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Prevention and Control Measures |
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455 | (1) |
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Measures of Quality of Care |
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456 | (1) |
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Study Designs Used to Examine Risk Factors |
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456 | (1) |
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457 | (4) |
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Case Study 16.2 Cost-Effectiveness of HIV Screening |
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457 | (4) |
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End-of-Chapter Case Exercises |
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461 | (1) |
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462 | (5) |
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Chapter 17 Alzheimer's Disease |
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467 | (42) |
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Introduction to Alzheimer's Disease |
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468 | (5) |
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Impact of Alzheimer's Disease |
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473 | (8) |
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Case Study 17.1. Alzheimer's Disease Incidence, Prevalence, and Mortality |
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480 | (1) |
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481 | (6) |
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Case Study 17.2. Screening for Cognitive Impairment: The Mini-Mental State Examination |
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484 | (3) |
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487 | (4) |
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Challenges to the Epidemiologic Study of Alzheimer's Disease |
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491 | (2) |
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493 | (4) |
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Case Study 17.3 Study Designs and Measures of Association (Example: Smoking and Alzheimer's Disease) |
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494 | (3) |
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End-of-Chapter Case Exercises |
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497 | (1) |
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498 | (11) |
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Chapter 18 Epidemiology and Leadership |
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509 | (24) |
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509 | (1) |
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Definitions and Distinctions |
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510 | (1) |
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The Role of Epidemiology in Defining Leadership |
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511 | (2) |
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Epidemiology and the Science and Art of Leadership |
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513 | (2) |
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Epidemiology and Evidence-Based Medicine, Management, and Public Health |
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515 | (4) |
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519 | (3) |
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Systems Thinking and Public Health Leadership |
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522 | (2) |
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Complex Adaptive Systems and Public Health Leadership |
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524 | (3) |
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Summary Case Study: Back to the Future |
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527 | (1) |
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527 | (1) |
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528 | (5) |
Capstone Cases |
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533 | (130) |
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Capstone Case A: Hepatitis A Outbreak in the Midwest |
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534 | (16) |
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Capstone Case B: Cardiovascular Disease |
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550 | (8) |
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Capstone Case C: Colorectal Cancer Screening |
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558 | (9) |
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Capstone Case D: Needs Assessment for Stroke Services |
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567 | (7) |
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Capstone Case E: Quality of Care in Seven Boston Hospitals |
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574 | (17) |
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Capstone Case F: Mortality in Kentucky: A Comparison of Jefferson and Fayette Counties |
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591 | (10) |
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Capstone Case G: Changes in Non-Group Coverage Under the Affordable Care Act |
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601 | (8) |
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Capstone Case H: Cost-Effectiveness Analysis of Type II Diabetes |
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609 | (8) |
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Capstone Case I: Sleep Duration and Cardiovascular Disease: A Cross-Sectional Study |
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617 | (4) |
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Capstone Case J: Obesity and Endometrial Cancer: Case Control and Prospective Cohort Studies |
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621 | (6) |
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Capstone Case K: Vitamin E, Selenium, and Prostate Cancer: A Randomized Clinical Trial |
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627 | (5) |
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Capstone Case L: Abortion and Breast Cancer: Confounding, Bias, and Effect Modification |
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632 | (10) |
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Capstone Case M: Clinical Decision Making: Acute Appendicitis in Kids |
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642 | (6) |
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Capstone Case N: Flemington Village |
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648 | (4) |
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Capstone Case O: Using Leadership and Managerial Epidemiology to Lead a Hospital Through Crisis |
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652 | (11) |
Answers for End-of-Chapter Case Exercises |
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663 | (20) |
Glossary |
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683 | (10) |
Appendix |
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693 | (4) |
Index |
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697 | (28) |
About the Contributors |
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725 | (4) |
About the Editor |
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729 | |