Ten lectures plus several contributions examine the progress made in the analysis of large molecules of m/z 10,000 and beyond. Explores how to apply this technology and ways of extending the analysis to even higher masses. Also examines how mass spectrometry techniques fit in with existing chemical and biochemical methods of structure analysis.
Fundamental Studies in the 252Cf-PDMS of Small Proteins; Secondary Ion
Mass Spectrometry: High-Mass Molecular and Cluster Ions; MS Analysis of Large
Peptides Synthesized by Recombinant DNA Technology. Application of FAB/MSMS
and Thermospray/MSMS in the Structural Characterization of Recombinant Eglin
C; Mechanisms of Desorption of Large Molecules and Clusters by Energetic
Particle Bombardment; Middle Molecules: Molecular and Fragment Ions at 1,000
to 14,000 AMU; Tandem Mass Spectrometry of Large Molecules; Strategies for
Analysis of High Mass Biopolymers; How to Obtain and How to Use Mass Spectral
Data at High Mass; Energy Transfer and Desorption at Surfaces; FAB and Tandem
MS for Structure Determination of Biomolecules: Success to M/Z 2000 and
Prospects for Higher Mass; Current Status of High-Mass Analysis by Fourier
Transform Mass Spectrometry; 252Cf- Plasma Desorption Mass Spectrometry of
Unprotected Tri- and Tetra-Deoxyribonucleotides; Dechlorination Reactions
Induced by Fast Atom Bombardment of the Glycopeptide Antibiotics Vancomycin
and Avoparcin.
