This fully revised 4th edition addresses the pathophysiology of vascular diseases encountered in vascular surgical practice. The principles of assessment and management of these conditions is also addressed. Many of the topics are not addressed or are inadequately addressed in clinical textbooks.
The book is pitched at trainees in vascular surgery and clinical vascular surgeons and is of use to medical students and basic surgical trainees.
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The homeostatic functions of the endothelial cells and their disfunction
in peripheral artery disease.- Pathophysiology of atherosclerosis.- Imaging
of atherosclerotic plaque.- Current and Emerging Therapies for
Atherosclerosis.- Pathophysiology of Angiogenesis and its Role in Vascular
Disease.- Vascular Biology of smooth muscle cells and arterial restenosis.-
Vascular Haemodynamics.- Computational Fluid Dynamics in the arterial system:
Implications for vascular disease and treatment.- Physiological Haemostasis.-
Hypercoagulable States.- Platelets as Mediators and Therapeutic Targets in
Cardiovascular Diseases.- An overview of abdominal aortic aneurysm pathology,
and progress towards a medical therapy.- Pathophysiology and management of
hereditary aneurysmal aortopathies.- Classification and Principles of
Management of Descending Aortic Pathologies.- Biomarkers in Vascular
Disease.- Pathophysiology and Principles of Management of Vasculitis and
Fibromuscular Dysplasia
Rob Fitridge is Professor of Vascular Surgery at Adelaide University and a Vascular and Endovascular Surgeon at the Royal Adelaide and Queen Elizabeth Hospitals. He served as President of the ANZ Society for Vascular Surgery (2010-2012) and President of the World Federation of Vascular Societies (WFVS) (2011-2012). He has been a member of the PAD working group of the International Working Group for the Diabetic Foot since 2014 and co-Chair since 2019. The most recent guideline was undertaken with the Society for Vascular Surgery and the European Society for vascular Surgery. He was also a member of the steering committee for the Global Vascular Guidelines for Chronic Limb-threatening Ischaemia (CLTI). His research interests include wound healing and amputation prevention in diabetes-related foot disease and CLTI.
Guilherme Pena is a Consultant Vascular and Endovascular Surgeon in the Vascular Unit, Flinders Medical Centre, Bedford Park, South Australia and Affiliate Senior Lecturer, Discipline of Surgery, Adelaide University, Adelaide, Australia. He trained in General and Vascular Surgery in Brazil and Australia. He completed a PhD in diabetes-related foot disease with Rob Fitridge and Prue Cowled and continues an active interest in this field.
Benjamin Thurston is a Consultant Vascular and Endovascular Surgeon in the Vascular and Endovascular Service, Central Adelaide Local Health Network, Adelaide, South Australia. He has active research interests including pathophysiology of atherosclerosis and AI innovations in vascular surgery practice.
Prue Cowled is an Affiliate Senior Lecturer, Discipline of Surgery, Adelaide University, Adelaide, South Australia. Her research interests have included reperfusion injury and diabetes-related foot disease.
