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Molecular Mechanism and Epochal Therapeutics of Ischemic Stroke and Dementia: Invited Papers from the International Symposium on Molecular Mechanism and Epochal Therapeutics for Ischemic Stroke and Dementia, Okayama, Japan 18-20 October 2002 [Kõva köide]

Edited by (Department of Neurology, Graduate School of Medicine and Dentistry, Okayama, Japan)
  • Formaat: Hardback, 520 pages, kaal: 1070 g, indexes
  • Sari: International Congress S. v. 1252
  • Ilmumisaeg: 08-Jul-2003
  • Kirjastus: Elsevier Health Sciences
  • ISBN-10: 0444512225
  • ISBN-13: 9780444512222
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  • Formaat: Hardback, 520 pages, kaal: 1070 g, indexes
  • Sari: International Congress S. v. 1252
  • Ilmumisaeg: 08-Jul-2003
  • Kirjastus: Elsevier Health Sciences
  • ISBN-10: 0444512225
  • ISBN-13: 9780444512222
Teised raamatud teemal:
This volume contains the papers presented at" The International Symposium on Molecular Mechanism and Epochal Therapeutics for Ischemic Stroke Dementia". Recent discoveries of the mechanism of ischemic neuronal death and Alzheimer's disease have made strong impact on the work being done by neuroscientists and clinicians in this area. This volume will definitely help in the progress of future basic and clinical investigations, to encourage strong scientific collaboration in elucidating the molecular mechanism and establish the epochal therapeutics of the diseases.
Preface v
Acknowledgements v
Role of intracellular signalling in cerebral ischemia
1(42)
Expression of PTEN and its phosphorylated form after transient middle cerebral artery occlusion in rat
3(10)
N. Omori
G. Jin
F. Li
W.R. Zhang
S.J. Wang
Y. Hamakawa
I. Nagano
Y. Manabe
M. Shoji
K. Abe
CRE-mediated gene expression in cerebral ischemia
13(8)
K. Kitagawa
T. Mabuchi
S. Sugiura
E. Omura-Matsuoka
T. Sasaki
S. Tanaka
M. Matsumoto
M. Hori
Poly (ADP-ribose) polymerase and brain ischemia
21(10)
R.J. Traystman
J. Kofler
M. Sawada
L.J. Martin
V.L. Dawson
P.D. Hurn
Effect of angiotensin II on cerebral edema following cerebral ischemia and reperfusion
31(12)
N. Hosomi
T. Takahashi
M. Kohno
Genes and genetic models of cerebral ischemia
43(48)
High-density DNA microarray analysis of gene expression following transient focal cerebral ischemia in mouse
45(12)
S.T. Hou
K.G. Becker
A. Baggley
G. Chen
J. Webster
Hypoxic induction of vascular endothelial growth factor is impaired in the spinal cord of the mice with mutant human SODI gene
57(8)
I. Nagano
T. Murakami
M. Shiote
H. Ilieva
Y. Manabe
M. Shoji
K. Abe
Early decrease of survival signal protein and DNA repair enzyme in spinal motor neuron of presymptomatic transgenic mice with a mutant SODI gene
65(8)
M. Shiote
H. Ilieva
I. Nagano
T. Murakami
T. Hayashi
M. Shoji
K. Abe
Alteration in survival signal induction by transient hypoxia in mice expressing mutant human SODI protein
73(10)
H. Ilieva
I. Nagano
T. Murakami
M. Shiote
M. Shoji
K. Abe
Renin-angiotensin system gene polymorphism in Japanese stroke patients
83(8)
T. Mizuno
M. Makino
Y. Fujiwara
J. Nagura
K. Shiga
K. Yoshikawa
K. Nakajima
M. Nakagawa
Neuroprotection with hypothermia and against inflammation
91(62)
Mild hypothermia enhances efficacy of neuroprotective agents in cerebral ischemia in rats
93(10)
T. Kamiya
Y. Katayama
Effects of aging on hypothermic neuroprotection in acute stroke
103(6)
H. Naritomi
K. Nagatsuka
K. Miyashita
H. Oe
The effects of a free radical scavenger, edaravone, combined with mild hypothermia on ischemic brain damage following transient middle cerebral artery occlusion in rats
109(8)
C. Nito
T. Kamiya
S. Amemiya
K. Kato
Y. Katayama
Immunophilin ameliorates apoptotic neuronal cell death
117(6)
K.-i. Tanaka
N. Ogawa
Expression of FKBP12 after brain ischemia
123(6)
H. Kato
Effects of FK506 on chronic cerebral hypoperfusion-induced discrimination learning disabilities in Wistar rats
129(6)
K.-i. Tanaka
M. Nomura
N. Ogawa
FK506 facilitates the normalization of post-ischemic perturbation of protein kinases and tyrosine phosphorylation in the gerbil hippocampal CA1 sectors
135(6)
K.-i. Katsura
J. Kurihara
M. Watanabe
K. Takahashi
Y. Katayama
Nuclear factor-kappa B decoy protects spinal cord injury following ischemia reperfusion in rats
141(6)
M. Nishio
T. Yuguchi
C. Akiyama
T. Fuinaka
M. Taniguchi
Y. Nakajima
T. Yoshimine
Functional modulation of astrocytes by a novel agent ONO-2506 mitigates delayed infarct expansion with a wide therapeutic time window, inducing prompt neurological recovery through reduction of the extracellular level of glutamate
147(6)
T. Asano
N.N. Tateishi
T. Matsui
T. Mori
Y. Kagamiishi
S. Sato
N. Katsube
Molecular mechanisms and therapy for ischemic brain damage
153(80)
Caspases and upstream mechanisms in central nervous system ischemic injury
155(8)
M.A. Moskowitz
D.A. Le
M.J. Whalen
Spatiotemporal changes of free cholesterol and neutral lipids after transient focal cerebral ischemia in rats
163(8)
H. Kamada
K. Sato
M. Iwai
K. Ohta
W.R. Zhang
I. Nagano
M. Shoji
K. Abe
Apolipoprotein E influences neuronal death and repair
171(8)
K. Horsburgh
B. W. McColl
F. White
J. McCulloch
Suppression of protein synthesis after transient cerebral ischemia
179(14)
W. Paschen
T. Mengesdorf
C. Aufenberg
New vessel formation and expression of angiogenesis-related genes in brain after ischemia
193(10)
T. Hayashi
P.H. Chan
Therapeutic time window of rt-PA on embolic stroke in rat
203(6)
S. Okubo
H. Igarashi
H. Yamaguchi
K. Arii
M. Sakamaki
G. Mizukoshi
Y. Aoki
Y. Katayama
Expression of LOX-1 in spontaneously hypertensive rat carotid atherosclerotic lesions
209(4)
Y. Hamakawa
N. Omori
K. Sato
I. Nagano
M. Shoji
K. Abe
Expression of p-ERK and cytochrome C signals in rat brain neurons after transient MCAO
213(8)
F. Li
N. Omori
K. Sato
G. Jin
I. Nagano
Y. Manabe
M. Shoji
K. Abe
Protection against ischemic brain damage by GDNF affecting cell survival and death signals
221(12)
G. Jin
N. Omori
F. Li
I. Nagano
Y. Manabe
M. Shoji
K. Abe
Neurotrophic factors and gene therapy for stroke
233(64)
Neuroprotection by drug-induced growth factors
235(12)
Y. Zhu
J. Krieglstein
Neurotrophic factor delivery by encapsulated cell grafts
247(6)
I. Date
T. Shingo
T. Ohmoto
Gene therapy for cerebral arteries
253(6)
H. Ooboshi
S. Ibayashi
Therapeutic time window of glial cell line-derived neurotrophic factor after transient middle cerebral artery occlusion in rat
259(6)
W.R. Zhang
K. Sato
M. Iwai
K. Ota
K. Abe
Therapeutic time window of Ad-GDNF after transient middle cerebral artery occlusion in rat
265(10)
W.R. Zhang
K. Sato
M. Iwai
I. Nagano
K. Abe
Attenuation of neuronal cell death by SOD1 is associated with extracellular signal-regulated kinase after transient focal cerebral ischemia in mice
275(10)
N. Noshita
T. Hayashi
A. Saito
S. Okuno
T. Sugawara
C. Maier
P.H. Chan
Adenovirus-mediated gene transfer to ischemic brain
285(6)
J. Takada
Y. Kumai
H. Ooboshi
S. Ibayashi
M. Iida
The change of distribution and mRNA expression of brain-derived neurotrophic factor after intrastriatal hemorrhage
291(6)
Y. Kanda
K. Yamada
N. Aihara
H. Hida
H. Nishino
Imaging of brain function
297(48)
Assessment of neuroreceptor changes in healthy ageing and in Alzheimer's disease with emission tomography
299(10)
G.M. Knudsen
MR imaging in acute stroke
309(6)
K. Minematsu
New MEG technology for evaluating focal brain function
315(6)
T. Yoshimine
M. Taniguchi
A. Kato
D. Cheyne
S.E. Robinson
Imaging of remote areas after focal cerebral ischemia
321(8)
A. Tamura
M. Nakane
T. Kuroiwa
T. Nagaoka
K. Sano
Propagation of recurrent depolarization in the penumbra in the rat---use of in vivo cortical NADH fluorescence
329(8)
Y. Takeda
T. Higuchi
K. Morita
Quantitative aspects of neurovascular interaction
337(4)
I. Kanno
Predicting the pathological fate of focal cerebral ischemia using 1H-magnetic resonance spectroscopic imaging
341(4)
H. Igarashi
I.L. Kwee
S. Okubo
T. Nakada
Y. Katayama
Molecular mechanism of Alzheimer's disease and the therapeutic potentials
345(72)
Distinct functions of tau isoforms in Alzheimer's disease
347(8)
H. Mori
S. Kosaka
S. Arawaka
T. Tomiyama
γ-Cleavage and ε-cleavage of β-amyloid precursor protein
355(8)
M. Morishima-Kawashima
Y. Ihara
COX-2 expression in brains of patients with familial Alzheimer's disease
363(10)
S. Nogawa
M. Takao
S. Suzuki
K. Tanaka
A. Koto
Y. Fukuuchi
I. Hayakawa
Accumulation of amyloid β protein in Tg2576 mice
373(6)
T. Kawarabayashi
T. Murakami
E. Matsubara
M. Shoji
K. Abe
Molecular pathology of transgenic tau mice
379(4)
T. Murakami
T. Kawarabayashi
E. Matsubara
M. Shoji
K. Abe
Heat shock proteins reduce aggregation and facilitate degradation of tau protein
383(12)
F. Dou
W.J. Netzer
A. Takashima
H. Xu
Alzheimer's disease and melatonin
395(4)
E. Matsubara
M. Shoji
T. Murakami
T. Kawarabayashi
K. Abe
Aβ42 vaccine on the Tg2576 Alzheimer model mice
399(6)
M. Shoji
Y. Harigaya
E. Matsubara
T. Kawarabayashi
T. Murakami
N. Oomori
K. Sato
I. Nagano
K. Abe
Aβ vaccination of a genetic model of Alzheimer's disease
405(6)
H. Hasegawa
C. Janus
J. Pearson
J. McLaurin
P.M. Mathews
Y. Jiang
S.D. Schmidt
M.A. Chishti
P. Horne
D. Helsin
J. French
H.T.J. Mount
R.A. Nixon
M. Mercken
C. Bergeron
P.E. Fraser
D. Westaway
P. St. George-Hyslop
Somatosensory-evoked fields in Alzheimer's disease
411(6)
K. Inoue
T. Shirai
A. Hashizume
T. Harada
Y. Kaseda
Y. Mimori
S. Nakamura
M. Matsumoto
Activation of stem cell in ischemic brain
417(42)
Highly polysialylated neural cell adhesion molecule positive cells increased and changed localization in rat hippocampus with exposure to repeated kindled seizures
419(8)
K. Sato
M. Iwai
W.R. Zhang
H. Kamada
K. Ohta
I. Nagano
M. Shoji
K. Abe
Activation of neural stem cells after global brain ischemia
427(8)
M. Iwai
K. Sato
H. Kamada
W.R. Zhang
K. Ohta
N. Omori
I. Nagano
M. Shoji
K. Abe
Activation and proliferation of oligodendrocyte progenitor cells after brain ischemia in the rat
435(10)
K. Tanaka
S. Nogawa
D. Ito
S. Suzuki
T. Dembo
A. Kosakai
Cyclooxygenase-2 is involved in increased proliferation of neuronal progenitor cells in the ischemic mouse hippocampus
445(6)
T. Sasaki
K. Kitagawa
S. Sugiura
E. Omura-Matsuoka
S. Tanaka
Y. Yagita
H. Okano
M. Matsumoto
M. Hori
Comparison of proliferation of oligodendrocyte progenitor cells between young and aged rats after transient cerebral ischemia
451(8)
K. Ohta
M. Iwai
K. Sato
N. Omori
I. Nagano
M. Shoji
K. Abe
Stem cell therapy for ischemic brain
459(40)
Differentiation of bone marrow cells in culture and in vivo
461(4)
M. Miyazaki
K. Kataoka
R.J. Medina
T. Kageyama
N.-h. Huh
Treatment of stroke with marrow stromal cells
465(6)
M. Chopp
Y. Li
Transplantation of mesenchymal stem cells derived from the bone marrow into the demyelinated spinal cord
471(6)
A. Bizen
O. Honmou
M. Inoue
S. Iihoshi
K. Houkin
K. Hashi
Transplantation of neural stem cells into ischemic brain
477(6)
O. Honmou
Cell therapy for cerebral ischemia using vascular endothelial growth factor-secreting cells
483(6)
T. Shingo
I. Date
A. Yano
K. Kobayashi
A. Takeuchi
T. Yasuhara
T. Ohmoto
Transplantation of neural stem cells into epileptic brain
489(4)
Y. Matsumoto
A. Sindo
N. Kawai
K. Kunishio
S. Nagao
T. Miyazaki
T. Itano
Y. Okada
T. Shimazaki
H. Okano
Neural stem cells as therapeutic agents for CNS injuries and disorders
493(6)
H. Okano
Author index 499(4)
Keyword index 503