MRI of Brain Physiology: Novel MRI Methods and Clinical Applications delves into the intricate world of brain physiology, focusing on the latest magnetic resonance imaging (MRI) methods and their clinical applications. Designed for biomedical engineers, technologists, radiologists, neurologists, neurosurgeons, and clinical researchers, this resource bridges the gap between advanced imaging techniques and practical clinical use. It covers a wide spectrum of cerebral physiology, from microvascular and macrovascular dynamics to cerebrovascular reserve, neurovascular coupling, and cerebrospinal fluid pathways. Each of the core chapters has a tripartite structure: physiology (concepts of the physiological processes), imaging techniques, and clinical applications.
Readers will find detailed discussions on emerging MRI methods, including dynamic contrast, arterial spin labeling, and quantitative BOLD models. The book also addresses the functional impact of physiological changes on tissue microstructure and integrity, offering insights into multiparametric relaxation mapping and quantitative susceptibility mapping. Uniquely, this book gives a comparative approach to different brain physiological MRI methods, highlighting their strengths, limitations, and reliability.
