| Preface |
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ix | |
| Contributors |
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xi | |
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SECTION I INTRODUCTION TO BASIC NEUROSCIENCE |
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1 | (106) |
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1 Overview Of Brain Development |
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3 | (9) |
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2 Neurochemical Systems In The Central Nervous System |
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12 | (15) |
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3 Principles Of Electrophysiology |
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27 | (12) |
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4 Principles Of Signal Transduction |
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39 | (25) |
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5 Synaptic And Neural Plasticity |
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64 | (12) |
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6 Principles Of Molecular Biology |
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76 | (12) |
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7 Epigenetics Of Psychiatric Diseases |
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88 | (19) |
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SECTION II NEW METHODS AND NEW TECHNOLOGIES FOR PRECLINICAL AND CLINICAL NEUROBIOLOGY |
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107 | (114) |
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8 Transgenic Tools And Animal Models Of Mental Illness |
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109 | (14) |
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9 Application Of Stem Cells To Understanding Psychiatric Disorders |
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123 | (15) |
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10 Optogenetic Technologies For Psychiatric Disease Research: Current Status And Challenges |
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138 | (10) |
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11 Blood--Brain Barrier Opening And Drug Delivery Using Focused Ultrasound And Microbubbles |
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148 | (12) |
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12 Genetic Methodologies And Applications |
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160 | (12) |
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13 The Brain And Its Epigenome |
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172 | (11) |
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14 Network Methods For Elucidating The Complexity Of Common Human Diseases |
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183 | (16) |
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15 Brain Imaging Methodologies |
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199 | (13) |
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16 Image-Guided Brain Stimulation |
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212 | (9) |
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SECTION III PSYCHOTIC DISORDERS |
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221 | (144) |
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17 Diagnosis Of The Psychoses |
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223 | (9) |
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18 Genetics Of Schizophrenia And Bipolar Disorder |
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232 | (15) |
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19 Genomic Syndromes In Schizophrenia: Overlapping Phenotypes |
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247 | (9) |
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20 Neuroimaging Of Psychotic Disorders |
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256 | (13) |
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21 Cognitive And Motivational Neuroscience Of Psychotic Disorders |
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269 | (18) |
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22 Mouse Models Of Schizophrenia And Bipolar Disorder |
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287 | (14) |
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23 Cortical Gaba Neurons In Schizophrenia |
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301 | (10) |
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24 Synaptic Disease In Psychiatry |
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311 | (16) |
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25 Neurodevelopment And Schizophrenia |
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327 | (11) |
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26 Neurobiology Of Mental Illness Psychosis Proneness |
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338 | (8) |
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27 Psychotic Disorders: Neurochemistry And Pharmacotherapy |
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346 | (9) |
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28 The Neurobiology Of Bipolar Disorder |
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355 | (10) |
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SECTION IV MOOD DISORDERS |
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365 | (162) |
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29 The Diagnosis Of Mood Disorders |
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367 | (29) |
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30 Genetics Of Depression |
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396 | (15) |
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31 Animal Models Of Mood Disorders |
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411 | (14) |
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32 Molecular And Cellular Pathogenesis Of Depression And Mechanisms For Treatment Response |
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425 | (13) |
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33 Pathogenesis Of Depression: Clinical Studies |
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438 | (17) |
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34 Neural Circuitry Of Depression |
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455 | (15) |
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35 Neurobiology Of Depression In Later Life: Anatomy Of Melancholia |
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470 | (13) |
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36 Gonadal Steroids And Mood Disorders |
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483 | (13) |
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37 Depression And Medical Illness |
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496 | (12) |
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38 Treatments For Depression |
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508 | (19) |
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SECTION V ANXIETY DISORDERS |
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527 | (146) |
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39 Diagnosis Of Anxiety Disorders |
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529 | (8) |
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40 Genetics Of Anxiety Disorders |
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537 | (12) |
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41 Neurobiology Of Fear And Anxiety: Contributions Of Animal Models To Current Understanding |
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549 | (18) |
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42 Differential Roles Of Gaba Receptors In Anxiety |
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567 | (13) |
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43 Prefrontal Cortex Regulation Of Emotion And Anxiety |
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580 | (13) |
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44 Developmental Components Of Fear And Anxiety In Animal Models |
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593 | (13) |
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45 Functional Neurocircuitry And Neuroimaging Studies Of Anxiety Disorders |
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606 | (15) |
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46 Novel Treatment Approaches For Anxiety Disorders |
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621 | (15) |
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47 Pharmacotherapy Of Anxiety Disorders |
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636 | (10) |
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48 Neurobiology And Treatment Of OCD |
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646 | (16) |
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49 Neurobiology And Treatment Of PTSD |
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662 | (11) |
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SECTION VI SUBSTANCE USE DISORDERS |
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673 | (116) |
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50 Animal Models Of Addiction |
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675 | (8) |
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51 Cellular And Molecular Mechanisms Of Addiction |
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683 | (13) |
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52 The Genetic Basis Of Addictive Disorders |
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696 | (10) |
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53 Brain Development And The Risk For Substance Abuse |
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706 | (10) |
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54 Molecular Imaging In Addictive Disorders |
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716 | (16) |
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55 Brain, Reward, And Drug Addiction |
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732 | (10) |
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56 Magnetic Resonance Spectroscopy Studies In Substance Abusers |
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742 | (19) |
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57 Pharmacotherapy Of Substance Use Disorders |
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761 | (11) |
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58 Epidemiology Of Substance Use Disorders |
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772 | (17) |
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789 | (142) |
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59 Clinical And Neuropsychological Features Of Alzheimer's Disease |
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791 | (14) |
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60 The Genetics Of Alzheimer's Disease |
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805 | (5) |
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61 Experimental Animal Models Of Alzheimer's Disease |
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810 | (11) |
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62 Structural, Functional, And Molecular Neuroimaging Biomarkers For Alzheimer's Disease |
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821 | (13) |
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63 Fluid Biomarkers For Alzheimer's Disease |
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834 | (10) |
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64 Current Therapies For Alzheimer's Disease |
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844 | (10) |
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65 Disease-Modifying Therapies For Alzheimer's Disease |
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854 | (18) |
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872 | (15) |
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67 Clinical Features And Pathogenesis Of Frontotemporal Dementia |
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887 | (13) |
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68 Pathogenesis, Diagnosis, And Treatment Of Vascular And Mixed Dementias |
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900 | (31) |
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69 Clinical Features And Pathogenesis Of Prion Disease |
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SECTION VIII PSYCHIATRIC DISORDERS OF CHILDHOOD ONSET |
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931 | (134) |
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70 Epidemiology Of Neuropsychiatry And Developmental Disorders Of Childhood |
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933 | (11) |
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71 Rare Variants Of Substantial Effect In Psychiatric Disorders Of Childhood Onset |
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944 | (11) |
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72 Epigenetics In Early Life Programming |
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955 | (12) |
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73 Animal Models In Psychiatric Disorders Of Childhood Onset |
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967 | (13) |
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74 Neuropathology And Synaptic Alterations In Neurodevelopmental Disorders |
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980 | (15) |
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75 Functional Connectivity: Application To Developmental Disorders |
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995 | (15) |
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76 Intellectual Disability Syndromes |
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1010 | (12) |
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77 Autism Spectrum Disorders |
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1022 | (12) |
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78 Neurobiology Of Attention Deficit/Hyperactivity Disorder |
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1034 | (14) |
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79 Tourette Syndrome And TIC Disorders |
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1048 | (13) |
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80 Novel Therapeutics In Childhood Onset Psychiatric Disorders |
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1061 | (4) |
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SECTION IX SPECIAL TOPIC AREAS |
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1065 | (122) |
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81 DSM-5 Overview And Goals |
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1067 | (5) |
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82 The Infirmities Of Psychiatric Diagnosis |
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1072 | (4) |
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83 Toward Precision Medicine In Psychiatry: The Nimh Research Domain Criteria Project |
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1076 | (13) |
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84 The Neurobiology Of Personality Disorders: The Shift To DSM-5 |
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1089 | (14) |
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M. Mercedes Perez-Rodriguez |
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85 The Neurobiology Of Aggression |
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1103 | (9) |
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86 The Neurobiology Of Social Attachment |
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1112 | (15) |
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87 The Neurobiology Of Sleep |
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1127 | (17) |
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88 The Neurobiology Of Resilience |
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1144 | (27) |
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89 The Neurobiology Of Eating Disorders |
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1171 | (16) |
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| Index |
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1187 | |
