| Preface |
|
v | |
| Influenza: the scope of the problem |
|
| Public health and economic aspects |
|
|
|
|
3 | (6) |
|
|
|
The importance of global influenza surveillance for the assessment of the impact of influenza |
|
|
9 | (4) |
|
|
|
|
|
Influenza-related morbidity and mortality among children in developed and developing countries |
|
|
13 | (8) |
|
|
|
Influenza present: the impact of the 1999 / 2000 epidemic on morbidity and mortality in the UK |
|
|
21 | (4) |
|
|
|
|
|
|
|
|
|
Surveillance and assessment of influenza activity in the UK and Europe |
|
|
25 | (4) |
|
|
|
Recent progress in national policy against influenza in Japan |
|
|
29 | (4) |
|
|
|
Alternative models for estimating influenza-attributable P & I deaths in the US |
|
|
33 | (4) |
|
|
|
|
|
|
|
|
|
|
|
|
|
Influenza present: the impact of the 1999--2000 epidemic on morbidity and mortality in the USA |
|
|
37 | (6) |
|
|
|
|
|
|
|
|
|
|
|
|
|
The impact of pandemic influenza, with special reference to 1918 |
|
|
43 | (10) |
|
|
|
Influenza future: the impact of new vaccines and antivirals |
|
|
53 | (8) |
|
|
|
Quantifying the burden of influenza: a prospective household contact study in France |
|
|
61 | (6) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
How much are patients willing to pay for an earlier alleviation of influenza? |
|
|
67 | (6) |
|
|
|
|
|
|
|
|
|
|
|
|
|
Rapid flu test and neuraminidase inhibitors in healthy adults: a cost-benefit analysis |
|
|
73 | (8) |
|
|
|
|
|
|
|
Health economics in decision making for influenza management |
|
|
81 | (6) |
|
|
|
|
|
|
| Epidemiology and surveillance: human influenza viruses |
|
|
A global pattern for influenza activity |
|
|
87 | (8) |
|
|
|
|
|
|
|
The seasonality of human mortality: the role of influenza |
|
|
95 | (8) |
|
|
|
|
|
The value of a database in surveillance and vaccine selection |
|
|
103 | (4) |
|
|
|
|
|
|
|
|
|
Seven integrated influenza surveillance systems in Taiwan |
|
|
107 | (12) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Further development of influenza surveillance in China and global impact on influenza control |
|
|
119 | (4) |
|
|
|
Surveillance of influenza viruses in Guangdong Province, China in 1998: a preliminary report |
|
|
123 | (8) |
|
|
|
|
|
|
|
|
|
|
|
Surveillance of influenza: a pan European perspective |
|
|
131 | (8) |
|
|
|
Phylogenetic studies of South African influenza A viruses: 1997--1999 |
|
|
139 | (8) |
|
|
|
|
|
|
|
Predicting influenza evolution: the impact of terminal and egg-adapted mutations |
|
|
147 | (8) |
|
|
|
|
|
|
|
|
|
Early herald wave outbreaks of influenza in 1916 prior to the pandemic of 1918 |
|
|
155 | (8) |
|
|
|
|
|
|
|
|
|
|
|
|
|
The 1918 Spanish flu epidemic in Geneva, Switzerland |
|
|
163 | (6) |
|
|
| Epidemiology and surveillance: animal influenza viruses and zoonoses |
|
|
Global surveillance of animal influenza for the control of future pandemics |
|
|
169 | (4) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
The pig as an intermediate host for influenza A viruses between birds and humans |
|
|
173 | (6) |
|
|
|
Recent examples of human infection by animal and avian influenza A viruses in Hong Kong |
|
|
179 | (8) |
|
|
|
|
|
|
|
|
|
|
|
|
|
Two lineages of H9N2 influenza viruses continue to circulate in land-based poultry in southeastern China |
|
|
187 | (8) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Co-circulation of avian H9N2 and human H3N2 viruses in pigs in southern China |
|
|
195 | (6) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Influenza surveillance in poultry market and its inter-species transmission in Taiwan |
|
|
201 | (12) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Analyses of evolutionary and virulence divergency of Hong Kong H5N1 influenza A viruses isolated from humans |
|
|
213 | (12) |
|
|
|
|
|
|
|
|
|
Infection of grey seals and harbour seals with influenza B virus |
|
|
225 | (8) |
|
|
|
|
|
|
|
|
|
|
|
Antigenic and genetic diversity among swine influenza viruses in Europe |
|
|
233 | (8) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Evolving H3N2 and emerging H1N2 swine influenza viruses in the United States |
|
|
241 | (10) |
|
|
|
|
|
|
|
|
|
|
|
|
|
Isolation of influenza viruses from wild birds in the Volga River basin and in the North Caspian Region |
|
|
251 | (8) |
|
|
|
|
|
|
|
|
|
|
|
Phylogenetic analysis of the polymerase genes of five equine influenza A(H3N8) viruses isolated in France between 1993 and 1999 |
|
|
259 | (8) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Diagnostic methods |
|
|
Molecular methods for diagnosis of influenza |
|
|
267 | (8) |
|
|
|
|
|
PCR-based influenza A virus surveillance in European birds |
|
|
275 | (8) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Antibodies from lymphocytes used as diagnostic markers: a novel approach |
|
|
283 | (10) |
|
|
|
|
|
|
|
|
| Insights into the host defence mechanisms |
|
|
Memory and recall CD8+ T cell responses to the influenza A viruses |
|
|
293 | (8) |
|
|
|
|
|
|
|
Shaping the T cell response to influenza virus |
|
|
301 | (10) |
|
|
|
|
|
Roles of CD4+ T and B cells in influenza virus infection |
|
|
311 | (8) |
|
|
|
|
|
H2M- and MHC class II recycling-independent loading of a hemagglutinin-derived epitope |
|
|
319 | (8) |
|
|
|
|
|
|
|
|
|
Susceptibility and immunity to influenza A strains in Ig -- / -- mice |
|
|
327 | (6) |
|
|
|
|
|
|
|
|
|
Mechanism of heterosubtypic immunity to influenza A virus infection |
|
|
333 | (8) |
|
|
|
|
|
|
|
|
|
|
|
Lack of cross-protection between European H1N1 and H1N2 swine influenza viruses |
|
|
341 | (6) |
|
|
|
|
|
|
|
Analysis of influenza specific CTL responses in children using fibroblasts as stimulator and target cells |
|
|
347 | (6) |
|
|
|
|
|
|
|
|
|
|
|
|
|
The basal level of influenza specific antibody-secreting cells in healthy subjects |
|
|
353 | (10) |
|
|
|
|
|
|
|
|
|
|
|
|
| Insights into the structure and replication of the virus Surface glycoproteins |
|
|
Changes in the HA and NA genes prior to the emergence of HPAI H7N1 avian influenza viruses in Italy |
|
|
363 | (6) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Hemagglutinin residues of recent human A(H3N2) viruses that affect agglutination of chicken erythrocytes |
|
|
369 | (6) |
|
|
|
|
|
|
|
|
|
|
|
N-glycans attached to hemagglutinin in the head region and the stem domain control growth of influenza viruses by different mechanisms |
|
|
375 | (8) |
|
|
|
|
|
|
|
|
|
Multiple lineages co-circulation and genetic reassortment of the neuraminidase and hemagglutinin genes within influenza viruses of the same type / subtype |
|
|
383 | (6) |
|
|
|
|
|
|
|
|
|
|
| M gene products |
|
|
Structure--function relationship of the M2 ion channel of influenza A virus |
|
|
389 | (8) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Role of influenza virus M1 protein in the viral budding process |
|
|
397 | (8) |
|
|
|
|
|
|
|
|
|
The crystal structure of the influenza matrix protein M1 at neutral pH: M1-M1 protein interfaces can rotate in the oligomeric structures of M1 |
|
|
405 | (6) |
|
|
|
|
|
|
|
|
|
|
|
The influenza B virus BM2 protein may be involved in the ribonucleoprotein complexes through the binding with membrane protein M1 |
|
|
411 | (10) |
|
|
|
|
|
|
|
Identification of the functional domains of the matrix protein of influenza A/WSN/33 virus |
|
|
421 | (6) |
|
|
|
|
|
|
|
|
|
|
|
|
| Viral genome structure and replication |
|
|
Transcription of influenza A virus genes |
|
|
427 | (8) |
|
|
|
|
|
|
|
|
|
|
|
Influenza virus RNA encapsidation: discrimination for vRNA versus cRNA molecules |
|
|
435 | (16) |
|
|
|
|
|
|
|
Structure of the RNA inside influenza virus RNPs |
|
|
451 | (6) |
|
|
|
|
|
|
|
Type specificity of the viral RNA extremities of the human influenza A and C viruses |
|
|
457 | (6) |
|
|
|
|
|
Fine mapping of the subunit binding sites of influenza virus RNA polymerase |
|
|
463 | (8) |
|
|
|
|
|
|
|
Cold-sensitivity of polymerase complexes from human or avian influenza A viruses |
|
|
471 | (8) |
|
|
|
|
|
|
|
Protease activity of influenza virus RNA polymerase PA subunit |
|
|
479 | (8) |
|
|
|
|
|
|
|
|
|
|
| Virus-host interaction: at the cellular level |
|
|
Evaluation of influenza A virus receptors |
|
|
487 | (16) |
|
|
|
|
|
Interaction of the influenza virus nucleoprotein with F-actin |
|
|
503 | (10) |
|
|
|
|
|
|
|
|
|
Virus versus host: modulation of the host α/β interferon pathways by the influenza A virus NS1 protein |
|
|
513 | (8) |
|
|
|
|
|
Sialyl sugar chains as receptors and determinants of host range of influenza A viruses |
|
|
521 | (6) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Lectins in innate host defence against influenza virus |
|
|
527 | (6) |
|
|
|
|
|
|
| Virus-host interaction: pathogenic consequences |
|
|
Hemagglutinin and neuraminidase as determinants of influenza virus pathogenicity |
|
|
533 | (12) |
|
|
|
|
|
|
|
|
|
|
|
|
|
Characterization of the 1918 influenza virus hemagglutinin and neuraminidase genes |
|
|
545 | (6) |
|
|
|
|
|
|
|
|
|
Inhibition of influenza virus replication by nitric oxide |
|
|
551 | (6) |
|
|
|
|
|
|
|
|
|
Targeted influenza virus infection of endothelial cells and leucocytes |
|
|
557 | (16) |
|
|
|
|
|
|
|
|
|
Mechanisms of differential induction of apoptosis by H3N2 and H1N1 influenza viruses |
|
|
573 | (8) |
|
|
|
|
|
|
|
|
|
Influenza-induced bacterial infection: reduced number of airway macrophages |
|
|
581 | (6) |
|
|
|
|
|
Genetic approach to studying influenza pathogenesis |
|
|
587 | (4) |
|
|
|
|
|
Role of plasminogen-binding neuraminidase in influenza pathogenicity |
|
|
591 | (4) |
|
|
|
|
|
Molecular correlates of influenza A H5N1 virus pathogenesis in mice |
|
|
595 | (6) |
|
|
|
|
|
|
|
|
|
|
|
|
|
A mouse model of dual infection with influenza virus and Streptococcus pneumoniae |
|
|
601 | (8) |
|
|
|
|
|
Acute encephalitis--encephalopathy during influenza epidemics in Japanese children |
|
|
609 | (6) |
|
|
|
|
|
|
|
|
|
Detection of viral antigens in the encephalopathy brain by influenza A virus |
|
|
615 | (8) |
|
|
|
|
|
|
|
Hemorrhagic pneumonia by influenza virus: deaths in a low-risk group during the epidemic of dengue in Cuba |
|
|
623 | (8) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Impact of influenza on the functional status of frail older persons |
|
|
631 | (6) |
|
|
|
|
|
|
|
|
|
Indicators and significance of severity in influenza patients |
|
|
637 | (10) |
|
|
|
|
|
|
| Current strategies for improved control by vaccination Opportunities for improved use of existing vaccines |
|
|
Measuring the effect of influenza vaccination programs---the Japanese schoolchildren experience revisited |
|
|
647 | (8) |
|
|
|
|
|
|
|
|
|
|
|
|
|
Modeling the effects of updating the influenza vaccine on the efficacy of repeated vaccination |
|
|
655 | (6) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Recommendations for the use of inactivated influenza vaccines and other preventive measures |
|
|
661 | (4) |
|
|
|
|
|
|
|
Influenza vaccination recommended for all adults aged 50 years and older, United States |
|
|
665 | (6) |
|
|
|
|
|
|
|
Impact of influenza vaccination policies on staff coverage in long-term care facilities |
|
|
671 | (6) |
|
|
|
|
|
|
|
Informing consumers about influenza increases vaccine acceptance---the Denver experience |
|
|
677 | (4) |
|
|
|
An update on the use of influenza vaccination in Wales and the impact of changes in government policy |
|
|
681 | (8) |
|
|
|
Influenza vaccination in the Netherlands: a successful system approach |
|
|
689 | (8) |
|
|
|
|
|
|
|
|
|
|
|
|
|
Government policy change in 1997 was essential for the implementation of an influenza vaccination strategy for New Zealand |
|
|
697 | (6) |
|
|
|
|
|
Use of alternative sites to administer influenza vaccine improves acceptance by both physicians and patients |
|
|
703 | (4) |
|
|
|
Antibody responses in elderly to influenza vaccination in case of an antigenic mismatch |
|
|
707 | (6) |
|
|
|
|
|
|
|
|
|
|
|
Influenza vaccination is less effective for stimulating a Granzyme B response in older adults |
|
|
713 | (10) |
|
|
|
|
|
|
|
The epidemiology of influenza vaccination: implications for global vaccine supply for an influenza pandemic |
|
|
723 | (10) |
|
|
|
Influenza pandemic planning: review of a collaborative state and national process |
|
|
733 | (4) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Pandemic planning in a temperate country with no vaccine producer |
|
|
737 | (8) |
|
|
|
|
|
|
|
Influenza pandemic planning in the tropics (Singapore) |
|
|
745 | (6) |
|
|
|
Developing vaccines against potential pandemic influenza viruses |
|
|
751 | (10) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
A single radial haemolysis assay for antibody to H5 haemagglutinin |
|
|
761 | (6) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Cross-protection studies with H5 influenza viruses |
|
|
767 | (8) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Infection with H9N2 influenza viruses confers immunity against lethal H5N1 infection |
|
|
775 | (8) |
|
|
|
|
|
|
|
|
|
|
|
Vaccines against avian influenza A H9N2 viruses |
|
|
783 | (6) |
|
|
|
|
|
|
|
|
|
|
|
Evaluation of H9N2 influenza vaccines in Balb / c mice |
|
|
789 | (8) |
|
|
|
|
|
|
|
|
|
|
|
|
| Current strategies for improved control by antivirals Neuraminidase inhibitors: effectiveness |
|
|
Influenza virus neuraminidase inhibitors: clinical aspects |
|
|
797 | (10) |
|
|
|
Oral oseltamivir reduces febrile illness in patients considered at high risk of influenza complications |
|
|
807 | (6) |
|
|
|
|
|
|
|
Effective treatment of influenza with oral oseltamivir in a vaccinated population of high-risk patients |
|
|
813 | (4) |
|
|
|
|
|
|
|
Antiviral use during influenza outbreaks in long-term care facilities |
|
|
817 | (6) |
|
|
|
Zanamivir use during transmission of amantadine-resistant influenza A in a nursing home |
|
|
823 | (6) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
The effect of Relenza treatment on the early immune response induced after influenza vaccination |
|
|
829 | (6) |
|
|
|
|
|
|
|
|
|
A consideration of animal models used for study of influenza virus inhibitors |
|
|
835 | (4) |
|
|
|
Evaluation of neuraminidase inhibitors in the human experimental infection model |
|
|
839 | (6) |
|
|
|
Accumulation of segment 6 sgRNAs of influenza A viruses in the presence of neuraminidase inhibitors |
|
|
845 | (10) |
|
|
|
|
|
|
|
|
| Neuraminidase inhibitors: potential for resistance |
|
|
Mechanisms of resistance of influenza virus to neuraminidase inhibitors |
|
|
855 | (8) |
|
|
|
|
|
|
|
|
|
Influenza resistance to zanamivir generated in ferrets |
|
|
863 | (16) |
|
|
|
|
|
|
|
|
|
|
|
Methods for determining resistance to neuraminidase inhibitors |
|
|
879 | (8) |
|
|
|
|
|
|
|
Screening of susceptibility to Zanamivir of influenza viruses |
|
|
887 | (10) |
|
|
|
|
|
|
|
|
|
|
| Future prospects for improved control Nucleic acid vaccines |
|
|
DNA vaccination with HA or NP encoding plasmids results in rapid viral clearance after viral challenge |
|
|
897 | (8) |
|
|
|
|
|
|
|
Vaccination with DNA encoding conserved influenza viral proteins |
|
|
905 | (6) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Influenza HA DNA induces Th1 cells and protection despite limited antibody responses |
|
|
911 | (6) |
|
|
|
|
|
|
|
|
|
|
|
|
|
DNA immunization elicits high H1 antibody and protects chicken from AIV challenge |
|
|
917 | (6) |
|
|
|
|
|
|
|
|
|
Replicons from positive strand RNA viruses for naked RNA immunization against influenza |
|
|
923 | (8) |
|
|
|
|
|
|
|
|
| Attenuated influenza vaccines |
|
|
Efficacy and effectiveness of attenuated, cold-adapted, trivalent intranasal influenza vaccine |
|
|
931 | (8) |
|
|
|
Safety and effectiveness of the trivalent, cold-adapted influenza vaccine (CAIV-T) in children |
|
|
939 | (6) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Current strategies for the prevention of influenza by the Russian cold-adapted live influenza vaccine among different populations |
|
|
945 | (6) |
|
|
|
|
|
Live attenuated reassortant influenza vaccine prepared using A / Leningrad / 134 / 17 / 57 (H2N2) donor strain is genetically stable after replication in children 3-6 years of age |
|
|
951 | (4) |
|
|
|
|
|
|
|
|
|
|
|
|
|
Genes coding for polymerase proteins are essential for attenuation of the cold-adapted A / Leningrad / 134 / 17 / 57 (H2N2) influenza virus |
|
|
955 | (6) |
|
|
|
|
|
|
|
|
|
A new intranasal, modified-live virus vaccine for equine H3N8 influenza |
|
|
961 | (4) |
|
|
|
|
|
|
| Adjuvants, vectors and delivery systems |
|
|
Intranasal influenza vaccine: protective efficacy in children and adults |
|
|
965 | (4) |
|
|
|
|
|
|
|
|
|
|
|
Preclinical and clinical evaluation of a new virosomal intranasal influenza vaccine |
|
|
969 | (10) |
|
|
|
Nasal proteosome subunit flu vaccine elicits enhanced mucosal IgA, serum HAI and protection comparable to conventional injectable flu vaccine |
|
|
979 | (6) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Mucosal vaccination protects mice against influenza A heterosubtypic challenge |
|
|
985 | (8) |
|
|
|
|
|
|
|
Lipopeptide vaccines: a strategy for improving protective immunity against influenza |
|
|
993 | (6) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Immunogenicity and protection in mice given inactivated influenza vaccine, MPL, QS-21 or QS-7 |
|
|
999 | (8) |
|
|
|
|
|
|
|
|
| Genetically manipulated virus vaccines |
|
|
Eight-plasmid rescue system for influenza A virus |
|
|
1007 | (8) |
|
|
|
|
|
|
|
An efficient plasmid-driven system for the generation of influenza virus-like particles for vaccine |
|
|
1015 | (4) |
|
|
|
|
|
|
|
|
|
|
|
Genetic incompatibility among influenza A viruses |
|
|
1019 | (4) |
|
|
|
|
|
|
|
|
|
Compatibility of various avian HA subtypes with the genome of human influenza A viruses |
|
|
1023 | (6) |
|
|
|
|
|
|
|
|
|
Potential applications of influenza A virus vectors as tumor vaccines |
|
|
1029 | (8) |
|
|
|
|
| Index of authors |
|
1037 | (6) |
| Keyword index |
|
1043 | |
