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xix | |
Contributors |
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xxix | |
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1 Clinical Approach To Suspected Cancer |
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1 | (7) |
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2 | (1) |
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2 | (1) |
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2 | (1) |
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2 | (1) |
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3 | (1) |
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1.6 Nervous system tumours |
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3 | (1) |
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1.7 Upper gastrointestinal cancer |
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4 | (1) |
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1.8 Lower gastrointestinal cancer |
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4 | (1) |
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1.9 Gynaecological cancer |
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5 | (1) |
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1.10 Haematological cancer |
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5 | (1) |
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1.11 Head and neck cancer |
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6 | (1) |
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6 | (1) |
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1.13 Bone cancer and sarcoma |
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6 | (1) |
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1.14 Skin cancer---melanoma |
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7 | (1) |
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1.15 Skin cancer---non-melanoma |
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7 | (1) |
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1.16 Further reading and internet resources |
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7 | (1) |
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2 Concepts Of Multidisciplinary Management |
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8 | (40) |
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9 | (2) |
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11 | (1) |
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12 | (5) |
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17 | (5) |
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2.5 Principles of cancer diagnosis and management |
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22 | (5) |
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2.6 Principles of surgical oncology |
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27 | (2) |
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29 | (4) |
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33 | (9) |
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42 | (6) |
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3 Tumours Of The Head And Neck |
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48 | (22) |
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3.1 Principles of management for cancer of the head and neck |
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49 | (5) |
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3.2 Tumours of the eye, orbit, and ear |
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54 | (2) |
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3.3 Salivary gland cancers |
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56 | (2) |
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3.4 Nose, nasal cavity, and paranasal sinuses |
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58 | (1) |
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59 | (2) |
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61 | (1) |
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62 | (1) |
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63 | (1) |
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64 | (2) |
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3.10 Uncommon tumours of the head and neck |
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66 | (1) |
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3.11 Management of neck nodes |
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67 | (3) |
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4 Tumours Of The Central Nervous System |
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70 | (26) |
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4.1 Primary brain tumours |
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71 | (1) |
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4.2 Clinicopathology of brain tumours |
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72 | (2) |
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4.3 Presentation and general management of primary brain tumours |
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74 | (2) |
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4.4 Surgical management of primary brain tumours |
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76 | (2) |
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4.5 Radiotherapy for primary brain tumours |
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78 | (2) |
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4.6 Chemotherapy and new agents for primary brain tumours |
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80 | (1) |
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4.7 Outcome and management of recurrence in primary brain tumours |
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81 | (3) |
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4.8 Summary of management for primary brain tumours |
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84 | (1) |
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4.9 Brain metastases overview |
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85 | (2) |
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4.10 Treatment options for brain metastases |
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87 | (2) |
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4.11 Outcome and summary for brain metastases |
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89 | (1) |
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4.12 Spinal cord tumours overview |
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90 | (2) |
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4.13 Management of spinal cord tumours |
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92 | (1) |
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4.14 Outcome in spinal tumours |
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93 | (1) |
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4.15 Further reading and internet resources |
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94 | (2) |
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96 | (21) |
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5.1 Primary tracheal tumours |
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97 | (1) |
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97 | (1) |
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5.3 Diagnosis and staging of lung cancer |
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98 | (2) |
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5.4 Pathology of lung cancer |
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100 | (3) |
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5.5 Treatment of stage I and II non-small cell lung cancer |
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103 | (1) |
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5.6 Treatment of stage III non-small cell lung cancer |
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104 | (2) |
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5.7 Treatment of stage IV non-small cell lung cancer |
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106 | (3) |
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5.8 Small cell lung cancer |
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109 | (2) |
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111 | (1) |
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5.10 Large cell neuroendocrine carcinoma |
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112 | (1) |
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5.11 Malignant pleural mesothelioma |
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112 | (2) |
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114 | (3) |
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117 | (23) |
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6.1 Breast cancer overview |
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118 | (1) |
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6.2 Clinical presentation, diagnosis, and staging of breast cancer |
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119 | (6) |
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6.3 Management of breast cancer: Carcinoma in situ |
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125 | (1) |
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6.4 Loco-regional treatment of invasive breast cancer: Surgery |
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126 | (1) |
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6.5 Loco-regional treatment of invasive breast cancer: Radiation therapy |
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127 | (1) |
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6.6 Systemic treatment for early breast cancer |
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128 | (4) |
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6.7 Management of locally advanced breast cancer |
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132 | (1) |
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6.8 Management of recurrent and metastatic breast cancer (MBC) |
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133 | (4) |
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137 | (1) |
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6.10 BRCA and hereditary breast cancer |
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138 | (2) |
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7 Cancers Of The Gastrointestinal System |
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140 | (56) |
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7.1 Epidemiology of oesophageal cancer |
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141 | (2) |
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7.2 Treatment of localized disease for oesophageal cancer |
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143 | (2) |
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7.3 Treatment of advanced disease for oesophageal cancer |
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145 | (1) |
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7.4 Epidemiology of gastric cancer |
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145 | (3) |
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7.5 Treatment of localized disease for gastric cancer |
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148 | (1) |
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7.6 Treatment of advanced disease for gastric cancer |
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149 | (2) |
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7.7 Hepatocellular cancer |
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151 | (7) |
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7.8 Biliary tract tumours overview |
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158 | (7) |
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7.9 Pancreatic cancer overview |
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165 | (3) |
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7.10 Treatment of resectable pancreatic cancer |
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168 | (2) |
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7.11 Treatment of unresectable and metastatic pancreatic cancer |
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170 | (1) |
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7.12 Uncommon pancreatic tumours |
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171 | (1) |
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7.13 Tumours of the small intestine |
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172 | (2) |
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7.14 Colorectal cancer overview |
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174 | (2) |
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7.15 Clinical features, diagnosis, and staging of colorectal cancer |
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176 | (3) |
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7.16 Colorectal cancer: Localized disease |
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179 | (2) |
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7.17 Adjuvant treatment for colorectal cancer |
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181 | (4) |
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7.18 Treatment of advanced colorectal cancer |
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185 | (4) |
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7.19 Prognosis, follow-up, and management of recurrence of colorectal cancer |
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189 | (2) |
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191 | (5) |
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8 Cancers Of The Genitourinary System |
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196 | (38) |
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197 | (3) |
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8.2 Non-surgical management of cancer of the kidney |
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200 | (2) |
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8.3 Urothelial and bladder cancer overview |
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202 | (2) |
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8.4 Management of localized and muscle invasive disease of bladder cancer |
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204 | (2) |
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8.5 Management of advanced and metastatic disease of bladder cancer |
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206 | (2) |
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8.6 Management of non-transitional urothelial cancer |
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208 | (1) |
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8.7 Cancer of the ureter and renal pelvis |
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209 | (1) |
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8.8 Prostate cancer overview |
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210 | (1) |
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8.9 Clinical features, diagnosis, staging, natural history, screening, and prognosis of prostate cancer |
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211 | (3) |
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8.10 Treatment of localized disease for prostate cancer |
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214 | (3) |
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8.11 Treatment of advanced disease for prostate cancer |
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217 | (1) |
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8.12 Detection and treatment of recurrence of prostate cancer |
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218 | (2) |
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8.13 Palliative care and symptom control for prostate cancer |
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220 | (1) |
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8.14 Testicular cancer overview |
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221 | (2) |
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8.15 Clinical features, diagnosis, TIN, staging, and prognosis for testicular cancer |
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223 | (2) |
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8.16 Management of low stage seminoma testicular cancer |
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225 | (2) |
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8.17 Management of low stage non-seminoma testicular cancer |
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227 | (1) |
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8.18 Prognosis and management of advanced testicular cancer disease |
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228 | (2) |
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8.19 Testicular cancer follow-up |
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230 | (1) |
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8.20 Penile cancer overview |
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231 | (1) |
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8.21 Management of penile cancer |
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232 | (2) |
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9 Cancers Of The Female Genital System |
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234 | (53) |
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9.1 Cervical cancer overview |
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235 | (1) |
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9.2 Clinical features, investigations, staging, and prognosis of cervical cancer |
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236 | (2) |
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9.3 Management of cervical cancer |
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238 | (3) |
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9.4 Recurrent cervical cancer |
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241 | (1) |
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241 | (1) |
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9.6 Treatment-related morbidity for cervical cancer |
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242 | (1) |
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9.7 Newer approaches to cervical cancer |
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242 | (1) |
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243 | (3) |
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9.9 Management of endometrial cancer |
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246 | (1) |
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9.10 Role of radiotherapy |
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247 | (2) |
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9.11 Role of chemotherapy and hormonal agents |
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249 | (1) |
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9.12 Recurrence and metastasis |
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250 | (1) |
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251 | (4) |
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9.14 Epithelial ovarian cancer |
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255 | (2) |
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9.15 Investigations, staging, and prognosis for epithelial ovarian cancer |
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257 | (1) |
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9.16 Early stage disease of epithelial ovarian cancer |
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258 | (1) |
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9.17 Advanced stage disease of epithelial ovarian cancer |
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259 | (2) |
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9.18 Epithelial ovarian cancer: Recurrent disease |
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261 | (2) |
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9.19 Epithelial ovarian cancer: Palliative care issues and conclusion |
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263 | (1) |
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9.20 Malignant ovarian germ cell tumours |
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264 | (2) |
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9.21 Management of malignant ovarian germ cell tumours |
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266 | (2) |
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9.22 Prognosis, surveillance, and management of recurrence in malignant ovarian germ cell tumours |
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268 | (1) |
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9.23 Sex cord-stromal tumours |
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269 | (3) |
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9.24 Borderline ovarian tumours |
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272 | (1) |
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9.25 Uncommon ovarian tumours |
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273 | (1) |
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9.26 Gestational trophoblastic disease overview |
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273 | (5) |
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278 | (3) |
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9.28 Cancers of the vulva and vagina |
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281 | (6) |
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287 | (21) |
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10.1 Introduction, clinical features, and staging of cutaneous melanoma |
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288 | (1) |
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10.2 Management of loco-regional disease for cutaneous melanoma |
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289 | (2) |
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10.3 Management of metastatic disease for cutaneous melanoma |
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291 | (4) |
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10.4 Non-cutaneous melanoma |
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295 | (1) |
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10.5 Basal cell carcinoma |
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296 | (4) |
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10.6 Squamous cell carcinoma |
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300 | (2) |
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10.7 Merkel cell carcinoma |
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302 | (1) |
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303 | (2) |
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10.9 Malignant skin adnexal tumours |
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305 | (1) |
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10.10 Skin cancer in organ transplant recipients |
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306 | (2) |
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11 Cancers Of The Musculoskeletal System |
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308 | (21) |
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11.1 Bone tumours overview |
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309 | (3) |
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312 | (2) |
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314 | (3) |
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317 | (2) |
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11.5 Soft tissue sarcomas overview |
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319 | (2) |
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11.6 Management of localized soft tissue sarcoma |
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321 | (2) |
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11.7 Management of locally advanced and metastatic disease for soft tissue sarcomas |
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323 | (2) |
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11.8 Retroperitoneal sarcoma |
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325 | (1) |
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11.9 Gastrointestinal stromal tumour |
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326 | (2) |
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11.10 Future directions in soft tissue sarcoma |
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328 | (1) |
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12 Tumours Of The Haemopoietic System |
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329 | (64) |
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330 | (2) |
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12.2 Clinical features, diagnosis, and staging for Hodgkin lymphoma |
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332 | (1) |
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12.3 Treatment of early stage Hodgkin lymphoma |
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333 | (2) |
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12.4 Treatment of advanced stage Hodgkin lymphoma |
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335 | (1) |
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12.5 Management of relapsed Hodgkin lymphoma |
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336 | (2) |
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12.6 Long-term toxicities and fertility issues of Hodgkin lymphoma |
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338 | (1) |
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12.7 Non-Hodgkin lymphoma |
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339 | (2) |
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12.8 Clinical features of non-Hodgkin lymphoma |
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341 | (2) |
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12.9 Treatment of low-grade disease |
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343 | (1) |
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12.10 Diffuse large B-cell lymphoma |
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344 | (1) |
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12.11 Mantle cell lymphoma |
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345 | (1) |
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12.12 Cutaneous non-Hodgkin lymphomas |
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346 | (1) |
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12.13 Extranodal involvement of non-Hodgkin lymphoma |
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347 | (2) |
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12.14 Adult acute lymphoblastic leukaemia |
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349 | (3) |
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12.15 Adult acute myeloid leukaemia |
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352 | (5) |
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12.16 Chronic myeloid leukaemia |
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357 | (5) |
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12.17 Chronic lymphocytic leukaemia |
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362 | (2) |
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12.18 Treatment for chronic lymphocytic leukaemia |
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364 | (2) |
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12.19 Hairy cell leukaemia |
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366 | (2) |
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12.20 Myelodysplasia syndrome overview |
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368 | (2) |
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12.21 Clinical features, staging, and prognosis of myelodysplastic syndrome |
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370 | (1) |
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12.22 Treatment for myelodysplastic syndrome |
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370 | (4) |
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374 | (3) |
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12.24 Staging, prognosis, and treatment response criteria for multiple myeloma |
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377 | (1) |
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12.25 Treatment for multiple myeloma |
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378 | (6) |
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12.26 Solitary plasmacytoma |
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384 | (1) |
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12.27 Monoclonal gammopathy of undetermined significance |
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385 | (1) |
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12.28 Smouldering myeloma |
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386 | (1) |
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12.29 Waldenstrom's macroglobulinemia |
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387 | (1) |
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388 | (1) |
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389 | (1) |
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12.32 Heavy chain disease |
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390 | (1) |
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12.33 Histiocyte disorders |
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391 | (2) |
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393 | (17) |
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13.1 Thyroid cancer overview |
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394 | (2) |
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13.2 Treatment of differentiated thyroid cancer |
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396 | (3) |
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13.3 Treatment of medullary carcinoma thyroid |
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399 | (2) |
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13.4 Treatment of anaplastic carcinoma thyroid |
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401 | (1) |
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13.5 Primary thyroid lymphoma |
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402 | (1) |
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403 | (1) |
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13.7 Adrenocortical carcinoma |
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404 | (2) |
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13.8 Neuroendocrine tumours |
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406 | (4) |
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410 | (15) |
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411 | (2) |
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413 | (3) |
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14.3 Paediatric central nervous system tumours |
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416 | (5) |
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14.4 Paediatric solid tumours and kidney tumours |
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421 | (1) |
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422 | (1) |
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423 | (1) |
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14.7 Other paediatric tumours and Langerhans cell histiocytosis |
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424 | (1) |
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424 | (1) |
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15 Oncological Emergencies And Acute Oncology |
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425 | (25) |
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15.1 Oncological emergencies and acute oncology |
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426 | (1) |
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15.2 Tumour lysis syndrome |
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426 | (1) |
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427 | (1) |
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428 | (1) |
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429 | (1) |
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430 | (1) |
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430 | (1) |
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431 | (2) |
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15.9 Catheter associated infections |
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433 | (1) |
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15.10 Nausea, vomiting, and diarrhoea |
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433 | (1) |
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15.11 Vascular complications |
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434 | (2) |
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15.12 Stridor and airway obstruction |
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436 | (1) |
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15.13 Superior vena cava obstruction |
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437 | (1) |
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15.14 Gastrointestinal obstruction |
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438 | (1) |
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15.15 Urinary tract obstruction |
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438 | (1) |
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15.16 Thrombocytopenia and disseminated intravascular coagulation |
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439 | (1) |
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15.17 Gastrointestinal bleeding |
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440 | (1) |
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15.18 Genitourinary bleeding |
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441 | (1) |
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442 | (1) |
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442 | (1) |
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443 | (1) |
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15.22 Brain metastases and raised intracranial pressure |
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444 | (1) |
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15.23 Spinal cord compression |
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444 | (1) |
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15.24 Impending and pathological fractures |
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445 | (1) |
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15.25 Immunotherapy-related emergencies |
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446 | (4) |
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16 Special Situations In Oncology |
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450 | (32) |
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16.1 Teenage and young adult malignancies |
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451 | (2) |
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16.2 Cancer in older people |
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453 | (3) |
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16.3 Cancer in pregnant women |
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456 | (3) |
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16.4 Cancer of unknown primary site |
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459 | (2) |
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16.5 Fertility and cancer |
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461 | (1) |
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462 | (3) |
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465 | (1) |
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466 | (2) |
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468 | (1) |
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469 | (3) |
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16.11 Lifestyle choices after cancer |
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472 | (3) |
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16.12 Complementary therapies |
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475 | (2) |
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16.13 Supportive care during chemotherapy |
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477 | (5) |
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482 | (31) |
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483 | (7) |
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490 | (3) |
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17.3 Malignant bowel obstruction |
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493 | (2) |
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495 | (1) |
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496 | (1) |
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497 | (1) |
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498 | (1) |
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499 | (2) |
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501 | (1) |
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17.10 Cancer-related fatigue |
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502 | (1) |
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503 | (1) |
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504 | (1) |
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505 | (1) |
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506 | (1) |
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507 | (1) |
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508 | (5) |
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18 Clinical Management Of Cancers---Flowcharts |
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513 | (18) |
Appendix 1 Systemic therapy regimens |
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531 | (6) |
Appendix 2 Radiotherapy fractionation |
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537 | (8) |
Appendix 3 Glomerular filtration rate |
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545 | (2) |
Index |
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547 | |