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Oxford Desk Reference: Oncology [Kõva köide]

Edited by (Consultant Clinical Oncologist, Norfolk and Norwich University Hospital, Norwich, UK), Edited by (Professor Emeritus, University of East Anglia, Norfolk, UK), Edited by , Edited by (Senior Specialist Registrar in Medical Oncology, Addenbrooke's Hospital, Cambridge, )
  • Formaat: Hardback, 736 pages, kõrgus x laius x paksus: 247x194x45 mm, kaal: 1395 g, 50 black and white photographs and 150 line drawings
  • Sari: Oxford Desk Reference Series
  • Ilmumisaeg: 09-Jun-2011
  • Kirjastus: Oxford University Press
  • ISBN-10: 0199235635
  • ISBN-13: 9780199235636
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    • Oxford Medicine Online e-raamatud
  • Formaat: Hardback, 736 pages, kõrgus x laius x paksus: 247x194x45 mm, kaal: 1395 g, 50 black and white photographs and 150 line drawings
  • Sari: Oxford Desk Reference Series
  • Ilmumisaeg: 09-Jun-2011
  • Kirjastus: Oxford University Press
  • ISBN-10: 0199235635
  • ISBN-13: 9780199235636
Teised raamatud teemal:
This easy-to-read, practical guide distils and compiles all the disparate literature on cancer into one succinct volume. With most of the topics fitting onto a double-page spread it allows for quick reference whilst on the ward. The text also includes the essential, evidence-based clinical guidelines needed for the safe and effective management of patients with cancer.

All aspects of cancer and its management are covered, including prevention, screening, diagnosis and treatment. This practical guide also offers information about coping with the physical and social issues that may arise with a diagnosis of cancer, such as insurance, travel and survivorship. A unique chapter of management flow charts assists fast, appropriate decision-making. Multidisciplinary management and palliative care are also covered in detail.
List of abbreviations
xv
List of contributors
xix
1 Introduction
1(2)
An approach to the oncology consultation
2(1)
1 Clinical approach to suspected cancer
3(14)
Lung cancer
4(1)
Breast cancer
5(1)
Urological cancer
6(1)
Nervous system tumours
7(1)
Upper gastrointestinal cancer
8(1)
Lower gastrointestinal cancer
9(1)
Gynaecological cancer
10(1)
Haematological cancer
11(1)
Head and neck cancer
12(1)
Thyroid cancer
13(1)
Bone cancer and sarcoma
14(1)
Skin cancer---melanoma
15(1)
Skin cancer---non-melanoma
16(1)
3 Concepts of multidisciplinary management
17(38)
Cancer prevention
18(4)
Cancer screening
22(2)
Cancer genetics
24(4)
Genetic counselling
28(4)
Principles of cancer diagnosis and management
32(6)
Principles of surgical oncology
38(4)
Radiotherapy
42(4)
Principles of systemic therapy
46(9)
4 Site-specific cancer management
55(512)
Head & neck cancer
Principles of management for cancer of the head and neck
58(4)
Tumours of the eye, orbit, and ear
62(2)
Salivary gland cancers
64(2)
Nose, nasal cavity, and paranasal sinuses
66(2)
Nasopharynx
68(2)
Lip and oral cavity
70(2)
Oropharynx
72(1)
Hypopharynx
73(1)
Larynx
74(2)
Uncommon tumours of head and neck
76(2)
Management of neck nodes
78(4)
CNS tumours
Primary brain tumours: introduction
82(2)
Brain tumours: clinicopathology
84(2)
Brain tumours: presentation and general management
86(2)
Brain tumours: surgical management
88(4)
Brain tumours: radiotherapy
92(4)
Brain tumours: chemotherapy and new agents
96(4)
Outcome and management of recurrence
100(4)
Brain tumours: summary of management
104(2)
Brain metastases: introduction
106(2)
Brain metastases: treatment options for brain metastases
108(3)
Brain metastases: outcome and summary
111(1)
Spinal cord tumours: introduction
112(2)
Spinal cord tumours: management
114(2)
Spinal cord tumours: outcome
116(2)
Thoracic tumours
Primary tracheal tumours
118(1)
Lung cancer: introduction, screening and smoking cessation
119(1)
Lung cancer: diagnosis and staging
120(3)
Lung cancer: pathology and therapeutic implications
123(1)
Treatment of stage I non-small-cell lung cancer
124(4)
Lung cancer: treatment of stages II and III non-small-cell lung cancer
128(2)
Chemotherapy in stage IV non-small-cell lung cancer
130(4)
Small-cell lung cancer
134(2)
Lung cancer: follow-up
136(2)
Pleural mesothelioma
138(4)
Thymic tumours
142(3)
Carcinoid
145(1)
Solitary fibrous tumour of the pleura
146(2)
Breast cancer
Breast cancer: introduction
148(2)
Breast cancer: pathogenesis and pathology
150(2)
Breast cancer: clinical features, diagnosis, staging, and prognostic factors
152(4)
Breast cancer: management of carcinoma in situ
156(2)
Management of breast cancer: surgery
158(2)
Breast cancer role of adjuvant radiotherapy
160(2)
Early stage breast cancer: adjuvant systemic treatment
162(4)
Locally advanced breast cancer concepts in management
166(2)
Management of recurrent and metastatic breast cancer
168(2)
Breast cancer: new agents and future perspectives
170(1)
Triple-negative breast cancer
171(1)
Bilateral breast cancer
172(1)
Paget's disease
173(1)
Male breast cancer
174(2)
Gastro-intestinal cancers
Oesophageal cancer: epidemiology and clinical features
176(2)
Oesophageal cancer: screening, diagnosis, and staging
178(2)
Oesophageal cancer: treatment of localized disease
180(2)
Oesophageal cancer: treatment of advanced disease, symptom control, and palliation
182(2)
Gastric cancer: introduction and clinical features
184(2)
Gastric cancer: screening, diagnosis, staging and prognosis
186(2)
Gastric cancer: treatment of localized disease
188(2)
Gastric cancer: treatment of advanced disease, symptom control, and palliative care
190(2)
Hepatocellular cancer: introduction
192(2)
Hepatocellular cancer: clinical features and staging
194(4)
Hepatocellular cancer: management
198(4)
Biliary tract tumours: introduction
202(2)
Biliary tract tumours: clinical features, staging, and prognosis
204(4)
Biliary tract tumours: management
208(4)
Pancreatic cancer: introduction
212(2)
Pancreatic cancer: diagnosis, staging, and prognosis
214(2)
Pancreatic cancer: treatment of resectable cancer
216(2)
Pancreatic cancer: treatment of unresectable and metastatic cancer
218(2)
Uncommon pancreatic tumours
220(2)
Tumours of small intestine
222(4)
Colorectal cancer: introduction
226(2)
Colorectal cancer: genetics, screening, and prevention
228(6)
Colorectal cancer: clinical features, diagnosis, and staging
234(4)
Colorectal cancer: treatment of localized disease
238(2)
Colorectal cancer: adjuvant treatment
240(4)
Colorectal cancer: treatment of advanced colorectal cancer
244(4)
Colorectal cancer: prognosis, follow-up, and management of recurrence
248(4)
Anal cancer: introduction
252(2)
Anal cancer: management
254(4)
Genito-urinary cancer
Cancer of kidney: introduction
258(2)
Cancer of kidney: prognosis and surgical management
260(2)
Cancer of kidney: non-surgical management
262(2)
Urothelial and bladder cancer: introduction
264(2)
Urothelial and bladder cancer: diagnosis, staging, and prognosis
266(2)
Bladder cancer: management of localized and muscle invasive disease
268(4)
Bladder cancer: management of advanced and metastatic disease
272(2)
Non-transitional urothelial cancer: management
274(1)
Prostate cancer: introduction
275(1)
Prostate cancer: clinical features, diagnosis, and staging
276(2)
Prostate cancer: natural history, screening, and prognosis
278(2)
Prostate cancer: treatment of localized disease
280(4)
Prostate cancer: treatment of advanced disease
284(2)
Prostate cancer: detection and treatment of recurrence
286(2)
Prostate cancer: palliative care and symptom control
288(2)
Testicular cancer: introduction
290(2)
Testicular cancer: clinical features, diagnosis, TIN, staging, and prognosis
292(4)
Testicular cancer: prognosis and management of advanced disease
296(4)
Testicular cancer: management of low stage seminoma
300(2)
Testicular cancer: management of low stage non-seminoma
302(2)
Testicular cancer: follow-up and rare testicular tumours
304(2)
Testicular cancer: fertility issues and survivorship
306(2)
Penile cancer: introduction
308(2)
Penile cancer: management
310(2)
Cancer of the ureter and renal pelvis
312(2)
Gynaecological cancers
Cervical cancer: epidemiology, screening, and pathology
314(2)
Cervical cancer: clinical features, investigations, staging, and prognosis
316(2)
Cervical cancer: primary management
318(5)
Cervical cancer: management of recurrence
323(1)
Cervical cancer: role of chemotherapy
324(1)
Cervical cancer: treatment-related morbidity
325(1)
Cervical cancer: newer approaches
326(2)
Endometrial cancer
328(2)
Endometrial cancer: diagnosis, screening, and pathology
330(2)
Endometrial cancer: investigations, staging, and prognosis
332(2)
Endometrial cancer: role of surgery
334(2)
Endometrial cancer: role of radiotherapy
336(2)
Endometrial cancer: role of chemotherapy and hormonal agents
338(2)
Endometrial cancer: recurrence and metastasis
340(2)
Uterine sarcomas
342(2)
Uterine sarcomas: management
344(2)
Epithelial ovarian cancer: introduction, pathology, and clinical features
346(2)
Epithelial ovarian cancer: investigations, staging, and prognosis
348(1)
Epithelial ovarian cancer: early stage disease
349(1)
Epithelial ovarian cancer: advanced stage disease
350(2)
Epithelial ovarian cancer: recurrent disease
352(2)
Epithelial ovarian cancer: palliative care issues
354(2)
Malignant ovarian germ cell tumours: introduction
356(2)
Malignant ovarian germ cell tumours: management
358(2)
Malignant ovarian germ cell tumours: prognosis, surveillance, and management of recurrence
360(2)
Sex cord-stromal tumours
362(6)
Gestational trophoblastic disease
368(2)
Gestational trophoblastic disease: diagnosis, staging and prognosis
370(2)
Gestational trophoblastic disease: low risk
372(2)
Gestational trophoblastic disease: high risk
374(2)
Gestational trophoblastic disease: special situations
376(2)
Cancers of vulva and vagina
378(4)
Management of vulval cancer
382(2)
Management of vaginal cancer
384(2)
Skin cancer
Basal cell carcinoma
386(4)
Squamous cell carcinoma
390(2)
Merkel cell carcinoma
392(2)
Malignant skin adnexal tumours
394(2)
Cutaneous melanoma: introduction, clinical features, and staging
396(2)
Cutaneous melanoma: management of non-metastatic disease
398(2)
Cutaneous melanoma: management of metastatic disease
400(4)
Non-cutaneous melanoma
404(2)
Bone tumours and soft tissue sarcomas
Bone tumours: introduction
406(2)
Bone tumours: clinical features, diagnosis, and staging
408(2)
Bone tumours: non-metastatic osteosarcoma
410(2)
Bone tumours: metastatic and recurrent osteosarcoma
412(2)
Bone tumours: Ewing's sarcoma
414(4)
Bone tumours: rare tumours
418(2)
Soft tissue sarcomas: introduction, clinical features, diagnosis, and staging
420(4)
Soft tissue sarcomas: management of localized disease
424(2)
Soft tissue sarcomas: management of locally advanced and metastatic disease
426(2)
Soft tissue sarcomas: special situations issues and future directions
428(2)
Gastrointestinal stromal tumour
430(2)
Future directions in soft tissue sarcoma
432(2)
Haematological malignancies
Hodgkin disease: introduction
434(2)
Hodgkin disease: clinical features, diagnosis, and staging
436(4)
Hodgkin disease: treatment of early stage disease
440(2)
Hodgkin disease: treatment of advanced disease
442(2)
Hodgkin disease: management of recurrence
444(2)
Hodgkin disease: long-term toxicities and fertility issues
446(2)
Non-Hodgkin lymphoma: introduction and pathology
448(4)
Non-Hodgkin lymphoma: clinical features, diagnosis, staging, and prognosis
452(2)
Non-Hodgkin lymphoma: treatment of low-grade disease
454(2)
Non-Hodgkin lymphoma: mantle cell lymphoma
456(2)
Non-Hodgkin lymphoma: the role of stem cell transplantation in aggressive disease
458(2)
Cutaneous Non-Hodgkin lymphomas
460(2)
Non-Hodgkin lymphoma: extranodal involvement
462(2)
Non-Hodgkin lympthoma: targeted therapy
464(2)
Adult acute lymphoblastic leukaemia
466(4)
Adult acute myeloid leukaemia
470(4)
Chronic myeloid leukaemia: introduction
474(2)
Chronic myeloid leukaemia: staging, prognosis, and treatment
476(3)
Chronic lymphocytic leukaemia: introduction
479(1)
Chronic lymphocytic leukaemia: clinical features and staging
480(2)
Chronic lymphocytic leukaemia: treatment
482(4)
Hairy cell leukaemia
486(2)
Myelodysplastic syndrome: introduction
488(4)
Myelodysplastic syndrome: clinical features, staging, and prognosis
492(2)
Myelodysplastic syndrome: treatment
494(6)
Multiple myeloma
500(4)
Multiple myeloma: staging, prognosis, and treatment response criteria
504(2)
Multiple myeloma: treatment
506(5)
Solitary plasmacytoma
511(1)
Monoclonal gammopathy of undetermined significance
512(2)
Smouldering myeloma
514(1)
Waldenstrom's macroglobulinemia
515(3)
Amyloidosis
518(2)
POEMS syndrome
520(1)
Heavy chain disease
521(1)
Histiocyte disorders
522(2)
Endocrine tumours
Thyroid cancer: introduction
524(2)
Thyroid cancer: management of differentiated cancer
526(4)
Thyroid cancer: medullary carcinoma
530(2)
Thyroid cancer: anaplastic carcinoma
532(1)
Primary thyroid lymphoma
533(1)
Parathyroid cancer
534(2)
Adrenocortical carcinoma
536(2)
Neuroendocrine tumours
538(2)
Paediatric tumours
Leukaemia
540(4)
Lymphoma
544(2)
Paediatric central nervous system tumours
546(6)
Paediatric solid tumours and kidney tumours
552(2)
Sarcomas
554(1)
Neuroblastoma
555(1)
Other paediatric tumours and Langerhans cell histiocytosis
556(2)
HIV related tumours
Kaposi's sarcoma
558(2)
Non-AIDS defining cancers
560(4)
Cancers of unknown primary
Cancer of unknown primary site
564(3)
5 Oncological emergencies
567(34)
Tumour lysis syndrome
568(1)
Hypercalcaemia
569(1)
Hyponatraemia
570(1)
Hyperkalaemia
571(1)
Hypoglycaemia
572(1)
Hyperuricaemia
573(1)
Febrile neutropenia
574(4)
Thrombocytopenia
578(2)
Catheter associated infections
580(2)
Raised intracranial tension
582(2)
Spinal cord compression
584(1)
Cardiac arrest: introduction
585(1)
Cardiac tamponade
586(2)
Venous thromboembolism (deep venous thrombosis and pulmonary embolism)
588(3)
Stridor and airway obstruction
591(1)
Superior vena caval obstruction
592(1)
Pleural effusion
593(1)
Gastrointestinal bleeding
594(1)
Intestinal obstruction
595(1)
Genitourinary bleeding
596(1)
Urinary tract obstruction
597(1)
Impending and pathological fractures
598(3)
6 Special situations in oncology
601(38)
Cancer in the elderly
602(2)
Cancer in pregnant women
604(4)
Fertility and cancer
608(2)
Late effects
610(4)
Cancer survivorship
614(2)
Travel
616(2)
Insurance
618(2)
Vaccination
620(4)
Lifestyle choices after cancer
624(4)
The internet and oncology
628(2)
Negligence and risk management in oncology
630(4)
Complementary therapies
634(2)
Supportive care during chemotherapy
636(3)
7 Palliative care
639(30)
Pain management
640(6)
Nausea and vomiting
646(3)
Malignant bowel obstruction
649(1)
Constipation
650(1)
Diarrhoea
651(1)
Hiccups
652(2)
Depression
654(2)
Delirium
656(1)
Oral care
657(1)
Cancer-related fatigue
658(1)
Cancer cachexia
659(1)
Breathlessness
660(1)
Cough
661(1)
Haemoptysis
662(1)
Symptom clusters
663(1)
End of life care
664(5)
8 Clinical management of cancer: flowcharts
669(22)
Bladder cancer
670(1)
Breast cancer
671(1)
Cervical cancer
672(1)
Colon cancer
673(1)
Endometrial cancer
674(1)
Epithelial ovarian cancer
675(1)
Hepatocellular cancer
676(1)
Small-cell lung cancer
677(1)
Non-small cell lung cancer
678(1)
Oesophageal cancer
679(1)
Pancreatic cancer
680(1)
Prostate cancer
681(1)
Rectal cancer
682(1)
Stomach cancer
683(1)
Testicular cancer: seminoma
684(1)
Testicular cancer: non-seminoma
685(1)
Thymic cancer
686(1)
Vaginal cancer
687(1)
Vulval cancer
688(1)
Unknown primary
689(2)
9 Appendix
691(14)
Systemic therapy regimens
692(3)
Radiotherapy fractionation
695(6)
Glomerular filtration rate
701(1)
Anatomical diagrams
702(3)
Index 705
Dr Thankamma V Ajithkumar MD, FRCP, FRCR, is at present a Consultant Clinical Oncologist at Norfolk and Norwich University Hospital. Previous to that he was a Consultant Clinical Oncologist at the Bristol Haematology & Oncology Centre, and a Specialist Registrar in Clinical Oncology at Addenbrookes Hospital, Cambridge. He has also lectured in clinical oncology at the Regional Cancer Centre in Kerala, India, and was employed as Assistant Professor there.

Dr Natalie Cook is a final year Specialist Registrar in Medical Oncology at Addenbrookes Hospital in Cambridge. She is currently completing her PhD in Oncology and has a special interest in medical education and gastrointestinal cancers.

Dr Helen Hatcher is a Consultant Medical Oncologist at Addenbrookes Hospital in Cambridge. She is also Honorary Consultant Medical Oncologist and Academic Consultant and Research Group Leader at Cambridge University. Her special interests are Teenage and Young Adult Cancers, Sarcoma and Ovarian cancer.



Ann Barrett, OBE, MD, FRCR, FRCP, FMed Sci, is Professor Emeritus at the University of East Anglia. She has won various prestigious awards, including the Frank Ellis Medal for the best publication in Clinical Oncology, the President's Medal of the Royal College of Radiologists and the ESTRO lifetime achievement award. Ann was Professor of Oncology and Deputy Dean of the School of Medicine at the University of East Anglia from 2002-2008, whilst also working as a Consultant in Oncology at Norfolk and Norwich University Hospitals NHS Foundation Trust.