Muutke küpsiste eelistusi

Oxford Textbook of Medicine 5th edition [Kõva köide]

Edited by , Edited by , Edited by
  • Formaat: Hardback, 4500 pages
  • Sari: Oxford Textbook
  • Ilmumisaeg: 17-May-2010
  • Kirjastus: Oxford University Press
  • ISBN-10: 0199204853
  • ISBN-13: 9780199204854
Teised raamatud teemal:
  • Kõva köide
  • Hind: 607,38 €*
  • * saadame teile pakkumise kasutatud raamatule, mille hind võib erineda kodulehel olevast hinnast
  • See raamat on trükist otsas, kuid me saadame teile pakkumise kasutatud raamatule.
  • Kogus:
  • Lisa ostukorvi
  • Tasuta tarne
  • Lisa soovinimekirja
  • Raamatukogudele
    • Oxford Medicine Online e-raamatud
  • Formaat: Hardback, 4500 pages
  • Sari: Oxford Textbook
  • Ilmumisaeg: 17-May-2010
  • Kirjastus: Oxford University Press
  • ISBN-10: 0199204853
  • ISBN-13: 9780199204854
Teised raamatud teemal:
The Oxford Textbook of Medicine is the foremost international textbook of medicine. Unrivalled in its coverage of the scientific aspects and clinical practice of internal medicine and its subspecialties, it is a fixture in the offices and wards of physicians around the world. More comprehensive, more authoritative, and more international than any other textbook, it focuses on offering practical guidance on clinical management and the prevention of disease. Three introductory chapters, On being a patient; Modern Medicine; and Global patterns of disease and medical practice, outline a philosophy which has always characterised the Oxford Textbook of Medicine. It is humane, thought-provoking, and aims to instil in readers an understanding of the role of medicine in society, and the contribution it can make to the health of populations. As always, there is detailed coverage of all areas of internal medicine. The integration of basic science and clinical practice is unparalleled, and throughout the book the implications of research for medical practice are explained. The core clinical medicine sections offer in-depth coverage of the traditional specialty areas. The Oxford Textbook of Medicine has unsurpassed detail on infectious diseases: the most comprehensive coverage to be found in any textbook of medicine. Other sections of note include pain; bioterrorism and forensic medicine; medical disorders in pregnancy; travel and expedition medicine; nutrition; the use of stem cells; regenerative medicine; and psychiatry and drug related problems in general medical practice. The section on acute medicine is designed to give rapid access to information when it is needed quickly. In response to detailed research, there have been substantial changes to ensure that the Oxford Textbook of Medicine continues to meet the needs of its readers. New chapter summaries give accessible overviews of the content. All 2,500 illustrations and photographs are now in full colour, and a new design ensures that the textbook is easy to read and navigate. The evidence-base and references have been entirely overhauled. And now, for the first time, the Oxford Textbook of Medicine is available in an online edition. All individual purchasers of the book will get 12 months free access to the online version, which contains the full text, figures and illustrations. It has a clear and easy-to-use interface, with excellent navigation and search and browse options. In addition, the online edition facilitates links to sources of related and further reading via PubMed, ISI and CrossRef. All the figures are downloadable into Powerpoint; an excellent tool when preparing presentations and lecturers.

Arvustused

...easy to read and organized intuitively, with an abundance of vivid full-color figures...The online version is superb, containing the full text as well as photographs and figures...Both the hardcover version and the online version of the Oxford Textbook of Medicine are worthy additions to any internist's library. Journal of the American Medical Association The 5th edition of the Oxford Textbook of Medicine remains unquestionably a superb reference book...the book is a masterpiece and it remains relevant to the global challenge of medicine British Journal of Hospital Medicine 'The latest edition benefits from internationally drawn expert contributors - they are true leaders in their respective fields...the book is a masterpiece and it remains relevant to the global challenge of medicine.' Hospital Medicine, September 2010 The newest edition of the Oxford Textbook of Medicine includes a comprehensive, well balanced and up-to-date section on cardiovascular medicine written by true experts. Clinical aspects are presented together with the science that underlies them. The OTM conveys to the reader as much crucial information as books many times its size. A. John Camm, BHF Professor of Clinical Cardiology, St. George's University of London, London, UK, April 2010 ...the doctor cannot help but be impressed by the sound advice that OTM5 brings to the consultation. Keep it by you throughout your career-and you will be educated, entertained and uplifted... Murray Longmore, author of the Oxford Handbook of Clinical Medicine The Oxford Textbook of Medicine is the ultimate medical resource-the easy way to review the core knowledge and learn about the key, clinically-relevant advances in all the medical specialities. The new edition appears to have maintained a truly authoritative edge and is now easily accessible with online access. Paul Leeson, Consultant Cardiologist, John Radcliffe Hospital, Oxford, UK

Muu info

Short-listed for FutureBook Digital Innovation Awards: Best Content Innovation 2011.Includes 12 months access to the online version
Volume 1
Contributors xxxi
Section 1 On being a patient
1.1 On being a patient
3(6)
Christopher Booth
Section 2 Modern medicine: foundations, achievements, and limitations
2.1 Scientific background to medicine
9(7)
2.1.1 Science in medicine: when, how, and what
9(3)
W.F. Bynum
2.1.2 Evolution: medicine's most basic science
12(4)
Randolph M. Nesse
Richard Dawkins
2.2 Medical ethics
16(6)
Tony Hope
2.3 Evidence-based medicine
22(26)
2.3.1 Bringing the best evidence to the point of care
22(5)
Paul P. Glasziou
2.3.2 Evidence-based medicine---does it apply to my particular patient?
27(4)
Louis R. Caplan
2.3.3 Large-scale randomized evidence: trials and meta-analyses of trials
31(14)
C. Baigent
R. Peto
R. Gray
S. Parish
R. Collins
2.3.4 The future of clinical trials
45(3)
Perry Nisen
Patrick Vallance
2.4 Funding of health care
48(17)
2.4.1 The evaluation and provision of effective medicines
48(6)
Michael D. Rawlins
2.4.2 Reasonableness and its definition in the provision of health care
54(4)
Norman Daniels
2.4.3 Priority setting in developed and developing countries
58(2)
Nigel Crisp
2.4.4 Sustaining innovation in an era of specialized medicine
60(5)
Henri A. Termeer
2.5 Complementary and alternative medicine
65(8)
E. Ernst
Section 3 Global patterns of disease and medical practice
3.1 Global burden of disease: causes, levels, and intervention strategies
73(7)
Ramanan Laxminarayan
Dean Jamison
3.2 Human population size, environment, and health
80(6)
A.J. McMichael
J.W. Powles
3.3 Avoiding disease and promoting health
86(1)
3.3.1 Preventive medicine
80(6)
J.W. Powles
3.3 Avoiding disease and promoting health
86(1)
3.3.1 Preventive medicine
80(6)
J.W. Powles
3.3 Avoiding disease and promoting health
86(26)
3.3.1 Preventive medicine
86(8)
David Mant
3.3.2 Medical screening
94(14)
Nicholas Wood
Malcolm Law
3.3.3 The importance of mass communication in promoting positive health
108(4)
Thomas Lom
3.4 Influence of wealth
112(7)
3.4.1 The cost of health care in Western countries
112(4)
Joseph White
3.4.2 A sinister pathogen corrupts two disciplines: the demographic entrapment of Middle Africa
116(3)
Maurice King
3.5 Human disasters
119(8)
Amartya Sen
Section 4 Cell biology
4.1 The cell
127(8)
George Banting
4.2 Molecular biology
135(17)
4.2.1 The human genome sequence
135(1)
Sydney Brenner
4.2.2 The genomic basis of medicine
136(16)
Pawet Stankiewicz
James R. Lupski
4.3 Cytokines
152(8)
Iain B. McInnes
4.4 Ion channels and disease
160(9)
Frances M. Ashcroft
4.5 Intracellular signalling
169(8)
R. Andres Floto
4.6 Apoptosis in health and disease
177(12)
Andrew H. Wyllie
Mark J. Arends
4.7 Discovery of embryonic stem cells and the concept of regenerative medicine
189(4)
Martin J. Evans
4.8 Stem cells and regenerative medicine
193(14)
Alexis J. Joannides
Roger Pedersen
Siddharthan Chandran
Section 5 Immunological mechanisms
Graham S. Ogg
5.1 Structure and function
207(28)
5.1.1 The innate immune system
207(6)
Paul Bowness
5.1.2 The complement system
213(11)
Marina Botto
Mark J. Walport
5.1.3 Adaptive immunity
224(11)
Paul Klenerman
5.2 Immunodeficiency
235(23)
D. Kumararatne
5.3 Allergy
258(9)
Pamela Ewan
5.4 Autoimmunity
267(13)
Antony Rosen
5.5 Principles of transplantation immunology
280(19)
Ross S. Francis
Kathryn J. Wood
Section 6 Principles of clinical oncology
6.1 Epidemiology of cancer
299(34)
A.J. Swerdlow
R. Peto
Richard S. Doll
6.2 The nature and development of cancer
333(25)
John R. Benson
Siong-Seng Liau
6.3 The genetics of inherited cancers
358(14)
Rosalind A. Eeles
6.4 Cancer immunity and clinical oncology
372(8)
Maries van den Broek
Lotta von Boehmer
Kunle Odunsi
Alexander Knuth
6.5 Cancer: clinical features and management
380(16)
R.L. Souhami
6.6 Cancer chemotherapy and radiation therapy
396(13)
Bruce A. Chabner
Jay Loeffler
Section 7 Infection
7.1 Pathogenic microorganisms and the host
409(11)
7.1.1 Biology of pathogenic microorganisms
409(4)
Duncan J. Maskell
7.1.2 Physiological changes, clinical features, and general management of infected patients
413(7)
Todd W. Rice
Gordon R. Bernard
7.2 The patient with suspected infection
420(40)
7.2.1 Clinical approach
420(3)
Christopher J. Ellis
7.2.2 Fever of unknown origin
423(5)
Steven Vanderschueren
Daniel Knockaert
7.2.3 Nosocomial infections
428(3)
I.C.J.W. Bowler
7.2.4 Infection in the immunocompromised host
431(10)
J. Cohen
7.2.5 Antimicrobial chemotherapy
441(19)
R.G. Finch
7.3 Immunization
460(5)
D. Goldblatt
M. Ramsay
7.4 Travel and expedition medicine
465(7)
C.P. Conlon
David A. Warrell
7.5 Viruses
472(526)
7.5.1 Respiratory tract viruses
473(9)
Malik Peiris
7.5.2 Herpesviruses (excluding Epstein-Barr virus)
482(19)
J.G.P. Sissons
7.5.3 Epstein-Barr virus
501(7)
M.A. Epstein
A.B. Rickinson
7.5.4 Poxviruses
508(5)
Geoffrey L. Smith
7.5.5 Mumps: epidemic parotitis
513(2)
B.K. Rima
7.5.6 Measles
515(10)
H.C. Whittle
P. Aaby
7.5.7 Nipah and Hendra virus encephalitides
525(2)
C.T. Tan
7.5.8 Enterovirus infections
527(9)
Philip Minor
Ulrich Desselberger
7.5.9 Virus infections causing diarrhoea and vomiting
536(5)
Philip Dormitzer
Ulrich Desselberger
7.5.10 Rhabdoviruses: rabies and rabies-related lyssaviruses
541(14)
M. J. Warrell
David A. Warrell
7.5.11 Colorado tick fever and other arthropod-borne reoviruses
555(2)
M.J. Warrell
David A. Warrell
7.5.12 Alphaviruses
557(4)
L.R. Petersen
D.J. Gubler
7.5.13 Rubella
561(3)
P.A. Tookey
J.M. Best
7.5.14 Flaviviruses excluding dengue
564(11)
L.R. Petersen
D.J. Gubler
7.5.15 Dengue
575(4)
Bridget Wills
Jeremy Farrar
7.5.16 Bunyaviridae
579(9)
J.W. LeDuc
Summerpal S. Kahlon
7.5.17 Arenaviruses
588(7)
J. ter Meulen
7.5.18 Filoviruses
595(5)
J. ter Meulen
7.5.19 Papillomaviruses and polyomaviruses
600(7)
Raphael P. Viscidi
Keerti V. Shah
7.5.20 Parvovirus B19
607(2)
Kevin E. Brown
7.5.21 Hepatitis viruses (excluding hepatitis C virus)
609(6)
N.V. Naoumov
7.5.22 Hepatitis C
615(5)
Paul Klenerman
K.J.M. Jeffery
J. Collier
7.5.23 HIV/AIDS
620(24)
Graz A. Luzzi
T.E.A. Peto
P. Goulder
C.P. Conlon
7.5.24 HIV in the developing world
644(6)
Alison D. Grant
Kevin M. De Cock
7.5.25 HTLV-1, HTLV-2, and associated diseases
650(3)
Kristien Verdonck
Eduardo Gotuzzo
7.5.26 Viruses and cancer
653(2)
R.A. Weiss
7.5.27 Orf
655(2)
David A. Warrell
7.5.28 Molluscum contagiosum
657(2)
David A. Warrell
7.5.29 Newly discovered viruses
659(4)
H.C. Hughes
7.6 Bacteria
663(1)
7.6.1 Diphtheria
664(6)
Delia B. Bethell
Tran Tinh Hien
7.6.2 Streptococci and enterococci
670(9)
Dennis L. Stevens
7.6.3 Pneumococcal infections
679(14)
Anthony Scott
7.6.4 Staphylococci
693(16)
Bala Hota
Robert A. Weinstein
7.6.5 Meningococcal infections
709(13)
P. Brandtzaeg
7.6.6 Neisseria gonorrhoeae
722(5)
D. Barlow
Jackie Sherrard
C. Ison
7.6.7 Enterobacteria
727(1)
7.6.7.1 Enterobacteria and bacterial food poisoning
727(8)
Hugh Pennington
7.6.7.2 Pseudomonas aeruginosa
735(3)
G.C.K.W. Koh
S.J. Peacock
7.6.8 Typhoid and paratyphoid fevers
738(7)
C.M. Parry
Buddha Basnyat
7.6.9 Intracellular klebsiella infections (donovanosis and rhinoscleroma)
745(3)
J. Richens
7.6.10 Anaerobic bacteria
748(6)
Anilrudh A. Venugopal
David W. Hecht
7.6.11 Cholera
754(5)
Aldo A.M. Lima
Richard L. Guerrant
7.6.12 Haemophilus influenzae
759(4)
Derrick W. Crook
7.6.13 Haemophilus ducreyi and chancroid
763(1)
Nigel O'Farrell
7.6.14 Bordetella infection
764(4)
Cameron Grant
7.6.15 Melioidosis and glanders
768(4)
S.J. Peacock
7.6.16 Plague: Yersinia pestis
772(4)
Michael B. Prentice
7.6.17 Other Yersinia infections: yersiniosis
776(1)
Michael B. Prentice
7.6.18 Pasteurella
777(3)
Marina S. Morgan
7.6.19 Francisella tularensis infection
780(3)
Petra C.F. Oyston
7.6.20 Anthrax
783(6)
Arthur E. Brown
Thira Sirisanthana
7.6.21 Brucellosis
789(6)
M. Monir Madkour
7.6.22 Tetanus
795(5)
C.L. Thwaites
Lam Minh Yen
7.6.23 Clostridium difficile
800(3)
John G. Bartlett
7.6.24 Botulism, gas gangrene, and clostridial gastrointestinal infections
803(7)
Dennis L. Stevens
Michael J. Aldape
Amy E. Bryant
7.6.25 Tuberculosis
810(21)
Richard E. Chaisson
Jean B. Nachega
7.6.26 Disease caused by environmental mycobacteria
831(5)
J.M. Grange
P.D.O. Davies
7.6.27 Leprosy (Hansen's disease)
836(12)
Diana N.J. Lockwood
7.6.28 Buruli ulcer: Mycobacterium ulcerans infection
848(2)
Wayne M. Meyers
Frangoise Portaels
7.6.29 Actinomycoses
850(6)
K.P. Schaal
7.6.30 Nocardiosis
856(1)
Roderick J. Hay
7.6.31 Rat-bite fevers
857(3)
David A. Warrell
7.6.32 Lyme borreliosis
860(6)
Gary P. Wormser
John Nowakowski
Robert B. Nadelman
7.6.33 Relapsing fevers
866(8)
David A. Warrell
7.6.34 Leptospirosis
874(5)
George Watt
7.6.35 Nonvenereal endemic treponematoses: yaws, endemic syphilis (bejel), and pinta
879(6)
David A. Warrell
7.6.36 Syphilis
885(11)
Basil Donovan
Linda Dayan
7.6.37 Listeriosis
896(3)
H. Hof
7.6.38 Legionellosis and legionnaires' disease
899(4)
J.T. MacFarlane
T.C. Boswell
7.6.39 Rickettsioses
903(16)
Philippe Parola
Didier Raoult
7.6.40 Scrub typhus
919(4)
George Watt
7.6.41 Coxiella burnetii infections (Q fever)
923(3)
T.J. Marrie
7.6.42 Bartonellas excluding B. bacilliformis
926(8)
Emmanouil Angelakis
Didier Raoult
Jean-Marc Rolain
7.6.43 Bartonella bacilliformis infection
934(5)
A. Llanos-Cuentas
C. Maguina-Vargas
7.6.44 Chlamydial infections
939(11)
David Taylor-Robinson
David Mabey
7.6.45 Mycoplasmas
950(11)
David Taylor-Robinson
Jorgen Skov Jensen
7.6.46 A check list of bacteria associated with infection in humans
961(37)
J. Paul
7.7 Fungi (mycoses)
998(37)
7.7.1 Fungal infections
998(20)
Roderick J. Hay
7.7.2 Cryptococcosis
1018(2)
William G. Powderly
7.7.3 Coccidioidomycosis
1020(3)
Gregory M. Anstead
John R. Graybill
7.7.4 Paracoccidioidomycosis
1023(5)
MA Shikanai-Yasuda
7.7.5 Pneumocystis jirovecii
1028(4)
Robert F. Miller
Laurence Huang
7.7.6 Penicillium marneffei infection
1032(3)
Thira Sirisanthana
7.8 Protozoa
1035(110)
7.8.1 Amoebic infections
1035(10)
Richard Knight
7.8.2 Malaria
1045(44)
David A. Warrell
Janet Hemingway
Kevin Marsh
Robert E. Sinden
Geoffrey A. Butcher
Robert W. Snow
7.8.3 Babesiosis
1089(1)
Philippe Brasseur
7.8.4 Toxoplasmosis
1090(8)
Oliver Liesenfeld
Eskild Petersen
7.8.5 Cryptosporidium and cryptosporidiosis
1098(7)
S.M. Caccio
7.8.6 Cyclospora and cyclosporiasis
1105(4)
R. Lainson
7.8.7 Sarcocystosis (sarcosporidiosis)
1109(2)
John E. Cooper
7.8.8 Giardiasis, balantidiasis, isosporiasis, and microsporidiosis
1111(7)
Martin F. Heyworth
7.8.9 Blastocystis hominis infection
1118(1)
Richard Knight
7.8.10 Human African trypanosomiasis
1119(8)
August Stich
7.8.11 Chagas disease
1127(7)
M.A. Miles
7.8.12 Leishmaniasis
1134(8)
A.D.M. Bryceson
Diana N.J. Lockwood
7.8.13 Trichomoniasis
1142(3)
Sharon Hillier
7.9 Nematodes (roundworms)
1145(40)
7.9.1 Cutaneous filariasis
1145(8)
Gilbert Burnham
7.9.2 Lymphatic filariasis
1153(7)
Richard Knight
D.H. Molyneux
7.9.3 Guinea worm disease (dracunculiasis)
1160(3)
Richard Knight
7.9.4 Strongyloidiasis, hookworm, and other gut strongyloid nematodes
1163(5)
Michael Brown
7.9.5 Gut and tissue nematode infections acquired by ingestion
1168(11)
David I. Grove
7.9.6 Parastrongyliasis (angiostrongyliasis)
1179(3)
Richard Knight
7.9.7 Gnathostomiasis
1182(3)
Valai Bussaratid
Pravan Suntharasamai
7.10 Cestodes (tapeworms)
1185(17)
7.10.1 Cystic hydatid disease (Echinococcus granulosus)
1185(3)
Armando E. Gonzalez
Pedro L. Moro
Hector H. Garcia
7.10.2 Cyclophyllidian gut tapeworms
1188(5)
Richard Knight
7.10.3 Cysticercosis
1193(6)
Hector H. Garcia
Robert H. Gilman
7.10.4 Diphyllobothriasis and sparganosis
1199(3)
David I. Grove
7.11 Trematodes (flukes)
1202(23)
7.11.1 Schistosomiasis
1202(10)
D.W. Dunne
B.J. Vennervald
7.11.2 Liver fluke infections
1212(4)
David I. Grove
7.11.3 Lung flukes (paragonimiasis)
1216(3)
Udomsak Silachamioon
Sirivan Vanijanonta
7.11.4 Intestinal trematode infections
1219(6)
David I. Grove
7.12 Nonvenomous arthropods
1225(12)
J. Paul
7.13 Pentastomiasis (porocephalosis, linguatulosis/ linguatuliasis)
1237(6)
David A. Warrell
Section 8 Sexually transmitted diseases and sexual health
8.1 Epidemiology of sexually transmitted infections
1243(7)
David Mabey
8.2 Sexual behaviour
1250(3)
Anne M. Johnson
Catherine H. Mercer
8.3 Sexual history and examination
1253(3)
Jackie Sherrard
Graz A. Luzzi
8.4 Vaginal discharge
1256(3)
Paul Nyirjesy
8.5 Pelvic inflammatory disease
1259(3)
David Eschenbach
8.6 Principles of contraception
1262(9)
John Guillebaud
Section 9 Chemical and physical injuries and environmental factors and disease
9.1 Poisoning by drugs and chemicals
1271(53)
J. A. Vale
S.M. Bradberry
D.N. Baterman
9.2 Injuries, envenoming, poisoning, and allergic reactions caused by animals
1324(37)
David A. Warrell
9.3 Injuries, poisoning, and allergic reactions caused by plants
1361(15)
9.3.1 Poisonous plants and fungi
1361(10)
Hans Persson
9.3.2 Common Indian poisonous plants
1371(5)
V.V. Pillay
9.4 Occupational and environmental health and safety
1376(17)
9.4.1 Occupational and environmental health
1376(12)
J.M. Harrington
Raymond M. Agius
9.4.2 Occupational safety
1388(5)
Lawrence Waterman
9.5 Environmental diseases
1393(56)
9.5.1 Heat
1393(2)
MA Stroud
9.5.2 Cold
1395(2)
M.A. Stroud
9.5.3 Drowning
1397(5)
Peter J. Fenner
9.5.4 Diseases of high terrestrial altitudes
1402(6)
Andrew J. Pollard
Buddha Basnyat
David R. Murdoch
9.5.5 Aerospace medicine
1408(8)
D.M. Denison
M. Bagshaw
9.5.6 Diving medicine
1416(6)
D.M. Denison
M.A. Glover
9.5.7 Lightning and electrical injuries
1422(4)
Chris Andrews
9.5.8 Podoconiosis (nonfilarial elephantiasis)
1426(3)
Gail Davey
9.5.9 Radiation
1429(3)
Jill Meara
9.5.10 Noise
1432(1)
Syed M. Ahmed
Tar-Ching Aw
9.5.11 Vibration
1432(4)
Tar-Ching Aw
9.5.12 Disasters: earthquakes, volcanic eruptions, hurricanes, and floods
1436(4)
Peter J. Baxter
9.5.13 Bioterrorism
1440(9)
Manfred S. Green
Section 10 Clinical pharmacology
10.1 Principles of clinical pharmacology and drug therapy
1449(30)
Kevin O'Shaughnessy
Section 11 Nutrition
11.1 Nutrition: macronutrient metabolism
1479(8)
Keith N. Frayn
11.2 Vitamins and trace elements
1487(18)
J. Powell-Tuck
M. Eastwood
11.3 Severe malnutrition
1505(10)
Alan A. Jackson
11.4 Diseases of ovemourished societies and the need for dietary change
1515(12)
J.I. Mann
A.S. Truswell
11.5 Obesity
1527(8)
I. Sadaf Farooqi
11.6 Artifical nutrition support
1535(14)
Jeremy Woodward
Section 12 Metabolic disorders
12.1 The inborn errors of metabolism: general aspects
1549(10)
Richard W.E. Watts
Timothy M. Cox
12.2 Protein-dependent inborn errors of metabolism
1559(37)
Georg F. Hoffmann
Stefan Kolker
12.3 Disorders of carbohydrate metabolism
1596(23)
12.3.1 Glycogen storage diseases
1596(8)
Philip Lee
Kaustuv Bhattacharya
12.3.2 Inborn errors of fructose metabolism 1604
1604(6)
Timothy M. Cox
12.3.3 Disorders of galactose, pentose, and pyruvate metabolism
1610(9)
Timothy M. Cox
12.4 Disorders of purine and pyrimidine metabolism
1619(17)
Richard W.E. Watts
12.5 The porphyrias
1636(16)
Timothy M. Cox
12.6 Lipid and lipoprotein disorders
1652(21)
P.N. Durrington
12.7 Trace metal disorders
1673(21)
12.7.1 Hereditary haemochromatosis
1673(15)
William J.H. Griffiths
Timothy M. Cox
12.7.2 Inherited diseases of copper metabolism: Wilson's disease and Menkes' disease
1688(6)
Michael L Schilsky
Pramod K. Mistry
12.8 Lysosomal disease
1694(25)
P.B. Deegan
Timothy M. Cox
12.9 Disorders of peroxisomal metabolism in adults
1719
Anthony S. Wierzbicki
12.10 Hereditary disorders of oxalate metabolism-the primary hyperoxalurias
1730(308)
Christopher J. Danpure
Dawn S. Milliner
12.11 Disturbances of acid-base homeostasis
1738(14)
R.D. Cohen
H.F. Woods
12.12 The acute phase response, amyloidoses and familial Mediterranean fever
1752(28)
12.12.1 The acute phase response and Creactive protein
1752(8)
M.B. Pepys
12.12.2 Hereditary periodic fever syndromes
1760(6)
Helen J. Lachmann
Philip N. Hawkins
12.12.3 Amyloidosis
1766(14)
M.B. Pepys
Philip N. Hawkins
12.13 α1 Antitrypsin deficiency and the serpinopathies
1780(7)
David A. Lomas
Index
Volume 2
Contributors xxxi
Section 13 Endocrine disorders
13.1 Principles of hormone action
1787(12)
Mark Gurnell
Jacky Burrin
V. Krishna Chatterjee
13.2 Disorders of the anterior pituitary gland
1799(20)
Niki Karavitaki
John A.H. Wass
13.3 Disorders of the posterior pituitary gland
1819(7)
Aparna Pal
Niki Karavitaki
John A.H. Wass
13.4 The thyroid gland and disorders of thyroid function
1826(19)
Anthony P. Weetman
13.5 Thyroid cancer
1845(6)
Anthony P. Weetman
13.6 Parathyroid disorders and diseases altering calcium metabolism
1851(18)
R. V. Thakker
13.7 Adrenal disorders
1869(32)
13.7.1 Disorders of the adrenal cortex
1869(22)
P.M. Stewart
13.7.2 Congenital adrenal hyperplasia
1891(10)
I.A. Hughes
13.8 The reproductive system
1901(47)
13.8.1 Ovarian disorders
1901(12)
Stephen Franks
Lisa J. Webber
13.8.2 Disorders of male reproduction
1913(15)
U. Srinivas-Shankar
F.C.W. Wu
13.8.3 Breast cancer
1928(12)
M. Cariati
L Holmberg
J. Mansi
P. Parker
G. Pichert
S. Pinder
E. Sawyer
R. Wilson
A. Purushotham
13.8.4 Benign breast disease
1940(2)
P. Jane Clarke
13.8.5 Sexual dysfunction
1942(6)
Ian Eardley
13.9 Disorders of growth and development
1948(28)
13.9.1 Normal growth and its disorders
1948(10)
Gary Butler
13.9.2 Puberty
1958(5)
I. Banerjee
P.E. Clayton
13.9.3 Normal and abnormal sexual differentiation
1963(13)
LA. Hughes
13.10 Pancreatic endocrine disorders and multiple endocrine neoplasia
1976(11)
N.M. Martin
S.R. Bloom
13.11 Disorders of glucose homeostasis
1987(72)
13.11.1 Diabetes
1987(62)
Colin Dayan
Gareth Williams
13.11.2 Hypoglycaemia
2049(10)
Vincent Marks
13.12 Hormonal manifestations of nonendocrine disease
2059(11)
Timothy M. Barber
John A.H. Wass
13.13 The pineal gland and melatonin
2070(5)
J. Arendt
Timothy M. Cox
Section 14 Medical disorders in pregnancy
14.1 Physiological changes of normal pregnancy
2075(4)
David J. Williams
14.2 Nutrition in pregnancy
2079(6)
David J. Williams
14.3 Medical management of normal pregnancy
2085(8)
David J. Williams
14.4 Hypertension in pregnancy
2093(10)
C.W.G. Redman
14.5 Renal disease in pregnancy
2103(5)
John D. Firth
14.6 Heart disease in pregnancy
2108(8)
Catherine EG. Head
14.7 Thrombosis in pregnancy
2116(5)
I.A. Greer
14.8 Chest diseases in pregnancy
2121(4)
Minerva Covarrubias
Tina Hartert
14.9 Liver and gastrointestinal diseases in pregnancy
2125(8)
Alexander Gimson
14.10 Diabetes in pregnancy
2133(7)
Moshe Hod
Yariv Yogev
14.11 Endocrine disease in pregnancy
2140(4)
John H. Lazarus
14.12 Neurological disease in pregnancy
2144(5)
G.G. Lennox
John D. Firth
14.13 The skin in pregnancy
2149(5)
Fenella Wojnarowska
14.14 Autoimmune rheumatic disorders and vasculitis in pregnancy
2154(11)
Sarah Germain
Catherine Nelson-Piercy
14.15 Infections in pregnancy
2165(8)
Lawrence Impey
14.16 Blood disorders specific to pregnancy
2173(8)
David J. Perry
Katharine Lowndes
14.17 Malignant disease in pregnancy
2181(5)
Robin A.F. Crawford
14.18 Prescribing in pregnancy
2186(5)
Peter Rubin
14.19 Benefits and risks of oral contraception
2191(5)
John Guillebaud
14.20 Benefits and risks of hormone replacement therapy
2196(5)
J.C. Stevenson
Section 15 Gastroenterological disorders
15.1 Structure and function of the gut
2201(4)
D.G. Thompson
15.2 Symptomatology of gastrointestinal disease
2205(5)
Graham Neale
15.3 Methods for investigation of gastrointestinal disease
2210(22)
15.3.1 Colonoscopy and flexible sigmoidoscopy
2210(4)
Christopher B. Williams
Brian P. Saunders
15.3.2 Upper gastrointestinal endoscopy
2214(5)
Adrian R.W. Hatfield
15.3.3 Radiology of the gastrointestinal tract
2219(7)
A.H. Freeman
15.3.4 Investigation of gastrointestinal function
2226(6)
Julian R.F. Walters
15.4 Common acute abdominal presentations
2232(12)
15.4.1 The acute abdomen
2232(5)
Chris Watson
15.4.2 Gastrointestinal bleeding
2237(7)
T.A. Rockall
H.M.P. Dowson
15.5 Immune disorders of the gastrointestinal tract
2244(13)
M.R. Haeney
15.6 The mouth and salivary glands
2257(30)
T. Lehner
S.J. Challacombe
15.7 Diseases of the oesophagus
2287(18)
Rebecca Fitzgerald
15.8 Peptic ulcer disease
2305(11)
Joseph Sung
15.9 Hormones and the gastrointestinal tract
2316(10)
A.E. Bishop
P.J. Hammond
J.M. Polak
S.R. Bloom
15.10 Malabsorption
2326(35)
15.10.1 Differential diagnosis and investigation of malabsorption
2326(4)
Julian R.F. Walters
15.10.2 Small bowel bacterial overgrowth
2330(5)
P.P. Toskes
15.10.3 Coeliac disease
2335(7)
Patrick C.A. Dubois
David A. van Heel
15.10.4 Gastrointestinal lymphoma
2342(5)
P.G. Isaacson
15.10.5 Disaccharidase deficiency
2347(5)
Timothy M. Cox
15.10.6 Whipple's disease
2352(2)
H.J.F. Hodgson
15.10.7 Effects of massive small bowel resection
2354(3)
R.J. Playford
15.10.8 Malabsorption syndromes in the tropics
2357(4)
V.I. Mathan
15.11 Crohn's disease
2361(10)
Miles Parkes
15.12 Ulcerative colitis
2371(13)
D.P. Jewell
15.13 Irritable bowel syndrome and functional bowel disorders
2384(5)
D.G. Thompson
15.14 Colonic diverticular disease
2389(6)
S.Q. Ashraf
M.G.W. Kettlewell
N.J. McC. Mortensen
15.15 Congenital abnormalities of the gastrointestinal tract
2395(10)
V.M. Wright
J.A. Walker-Smith
15.16 Cancers of the gastrointestinal tract
2405(12)
J.A. Bridgewater
S.P. Pereira
15.17 Vascular and collagen disorders
2417(7)
Graham Neale
15.18 Gastrointestinal infections
2424(11)
Davidson H. Hamer
Sherwood L. Gorbach
15.19 Structure and function of the liver, biliary tract, and pancreas
2435(9)
Alexander Gimson
Simon M. Rushbrook
15.20 Jaundice
2444(8)
R.P.H. Thompson
15.21 Hepatitis and autoimmune liver disease
2452(22)
15.21.1 Viral hepatitis-clinical aspects
2452(8)
H.J.F. Hodgson
15.21.2 Autoimmune hepatitis
2460(4)
H.J.F. Hodgson
15.21.3 Primary biliary cirrhosis
2464(4)
M.F. Bassendine
15.21.4 Primary sclerosing cholangitis
2468(6)
R.W. Chapman
15.22 Other disorders of the liver
2474(72)
15.22.1 Alcoholic liver disease
2474(6)
Stephen F. Stewart
Chris P. Day
15.22.2 Nonalcoholic steatohepatitis
2480(2)
Stephen F. Stewart
Chris P. Day
15.22.3 Cirrhosis and ascites
2482(11)
Kevin Moore
15.22.4 Hepatocellular failure
2493(12)
E Anthony Jones
15.22.5 Liver transplantation
2505(7)
Gideon M. Hirschfield
Michael ED. Allison
Graeme J.M. Alexander
15.22.6 Liver tumours---primary and secondary
2512(11)
William J.H. Griffiths
Simon M. Rushbrook
15.22.7 Hepatic granulomas
2523(4)
C.W.N. Spearman
Pauline de la Motte Hall
M.W. Sonderup
S.J. Saunders
15.22.8 Drugs and liver damage
2527(10)
J. Neuberger
15.22.9 The liver in systemic disease
2537(9)
J. Neuberger
15.23 Diseases of the gallbladder and biliary tree
2546(11)
J.A. Summerfield
15.24 Diseases of the pancreas
2557(22)
15.24.1 Acute pancreatitis
2557(10)
C.W. Imrie
R. Carter
15.24.2 Chronic pancreatitis
2567(7)
P.P. Toskes
15.24.3 Tumours of the pancreas
2574(5)
Martin Lombard
Ian Gilmore
15.25 Congenital disorders of the liver, biliary tract, and pancreas
2579(5)
J.A. Summerfield
15.26 Miscellaneous disorders of the bowel and liver
2584(9)
Alexander Gimson
Section 16 Cardiovascular disorders
16.1 Structure and function
2593(35)
16.1.1 Blood vessels and the endothelium
2593(10)
Patrick Vallance
16.1.2 Cardiac myocytes and the cardiac action potential
2603(15)
Kenneth T. MacLeod
Steven B. Marston
Philip A. Poole-Wilson
Nicholas J. Severs
Peter H. Sugden
16.1.3 Clinical physiology of the normal heart
2618(10)
David EL Wilcken
16.2 Clinical presentation of heart disease
2628(15)
16.2.1 Chest pain, breathlessness, and fatigue
2628(8)
J. Dwight
16.2.2 Syncope and palpitations
2636(7)
A.C. Rankin
A.D. McGavigan
S.M. Cobbe
16.3 Clinical investigation of cardiac disorders
2643(45)
16.3.1 Electrocardiography
2643(19)
Andrew R. Houghton
David Gray
16.3.2 Echocardiography
2662(9)
Adrian P. Banning
Andrew R.J. Mitchell
16.3.3 Cardiac investigation---nuclear and other imaging techniques
2671(7)
Nikant Sabharwal
Harald Becher
16.3.4 Cardiac catheterization and angiography
2678(10)
Edward D. Folland
16.4 Cardiac arrhythmias
2688(29)
S.M. Cobbe
A.D. McGavigan
A.C. Rankin
16.5 Cardiac failure
2717(19)
16.5.1 Clinical features and medical treatments
2717(12)
Martin R. Cowie
Badrinath Chandrasekaran
16.5.2 Cardiac transplantation and mechanical circulatory support
2729(7)
Jayan Parameshwar
16.6 Heart valve disease
2736(22)
Michael Henein
16.7 Diseases of heart muscle
2758(32)
16.7.1 Myocarditis
2758(6)
Jay W. Mason
16.7.2 The cardiomyopathies: hypertrophic, dilated, restrictive, and right ventricular
2764(18)
William J. McKenna
Perry Elliott
16.7.3 Specific heart muscle disorders
2782(8)
William J. McKenna
Perry Elliott
16.8 Pericardial disease
2790(7)
Michael Henein
16.9 Cardiac involvement in infectious disease
2797(33)
16.9.1 Acute rheumatic fever
2797(9)
Jonathan R. Carapetis
16.9.2 Infective endocarditis
2806(16)
William A. Littler
16.9.3 Cardiac disease in HIV infectiont
2822(4)
Peter F. Currie
16.9.4 Cardiovascular syphilis
2826(4)
Krishna Somers
16.10 Tumours of the heart
2830(4)
Thomas A. Traill
16.11 Cardiac involvement in genetic disease
2834(8)
Thomas A. Traill
16.12 Congenital heart disease in the adult
2842(31)
S.A. Thorne
16.13 Coronary heart disease
2873(80)
16.13.1 Biology and pathology of atherosclerosis
2873(8)
Clare Dollery
Peter Libby
16.13.2 Coronary heart disease: epidemiology and prevention
2881(17)
Harry Hemingway
Michael Marmot
16.13.3 Influences acting in utero and in early childhood
2898(4)
D.J.P. Barker
16.13.4 Management of stable angina
2902(9)
Adam D. Timmis
16.13.5 Management of acute coronary syndrome
2911(24)
Keith A.A. Fox
16.13.6 Percutaneous interventional cardiac procedures
2935(7)
Edward D. Folland
16.13.7 Coronary artery bypass surgery
2942(4)
Graham Cooper
16.13.8 The impact of coronary heart disease on life and work
2946(7)
Michael C. Petch
16.14 Diseases of the arteries
2953(21)
16.14.1 Thoracic aortic dissection
2953(6)
Andrew R.J. Mitchell
Adrian P. Banning
16.14.2 Peripheral arterial disease
2959(7)
Janet Powell
Alun Davies
16.14.3 Cholesterol embolism
2966(2)
Christopher Dudley
16.14.4 Takayasu's arteritis
2968(6)
Yasushi Kobayashi
16.15 The pulmonary circulation
2974(28)
16.15.1 Structure and function
2974(4)
Nicholas W. Morrell
16.15.2 Pulmonary hypertension
2978(14)
Nicholas W. Morrell
16.15.3 Pulmonary oedema
2992(10)
Nicholas W. Morrell
John D. Firth
16.16 Venous thromboembolism
3002(21)
16.16.1 Deep venous thrombosis and pulmonary embolism
3002(16)
Paul D. Stein
John D. Firth
16.16.2 Therapeutic anticoagulation
3018(5)
David Keeling
16.17 Hypertension
3023(60)
16.17.1 Essential hypertension---definition, epidemiology, and pathophysiology
3023(16)
Bryan Williams
16.17.2 Diagnosis, assessment, and treatment of essential hypertension
3039(18)
Bryan Williams
16.17.3 Secondary hypertension
3057(14)
Morris J. Brown
16.17.4 Mendelian disorders causing hypertension
3071(3)
Nilesh J. Samani
16.17.5 Hypertensive urgencies and emergencies
3074(9)
Gregory Y.H. Lip
D. Gareth Beevers
16.18 Chronic peripheral oedema and lymphoedema
3083(10)
Peter S. Mortimer
16.19 Idiopathic oedema of women
3093(4)
John D. Firth
Section 17 Critical care medicine
17.1 Cardiac arrest
3097(9)
Jasmeet Soar
Jerry P. Nolan
David A. Gabbott
17.2 Anaphylaxis
3106(9)
Anthony F.T. Brown
17.3 The clinical approach to the patient who is very ill
3115(7)
John D. Firth
17.4 Circulation and circulatory support in the critically ill
3122(10)
Michael R. Pinsky
17.5 Acute respiratory failure
3132(15)
Susannah Leaver
Timothy Evans
17.6 Management of raised intracranial pressure
3147(6)
David K. Menon
17.7 Sedation and analgesia in the critically ill
3153(5)
Gilbert Park
Maire P. Shelly
17.8 Discontinuing treatment of the critically ill patient
3158(3)
M.J. Lindop
17.9 Brainstem death and organ donation
3161(8)
M.J. Lindop
Section 18 Respiratory disorders
18.1 Structure and function
3169(13)
18.1.1 The upper respiratory tract
3169(4)
J.R. Stradling
S.E. Craig
18.1.2 Airways and alveoli
3173(9)
Peter D. Wagner
18.2 The clinical presentation of respiratory disease
3182(7)
Julian Hopkin
18.3 Clinical investigation of respiratory disorders
3189(38)
18.3.1 Respiratory function tests
3189(11)
G.J. Gibson
18.3.2 Thoracic imaging
3200(16)
Susan J. Copley
David M. Hansell
18.3.3 Bronchoscopy, thoracoscopy, and tissue biopsy
3216(11)
Pallav L Shah
18.4 Respiratory infection
3227(27)
18.4.1 Upper respiratory tract infections
3227(4)
P. Little
18.4.2 Pneumonia in the normal host
3231(12)
John G. Bartlett
18.4.3 Nosocomial pneumonia
3243(3)
John G. Bartlett
18.4.4 Pulmonary complications of HIV infection
3246(8)
Mark J. Rosen
18.5 The upper respiratory tract
3254(23)
18.5.1 Upper airways obstruction
3254(7)
J.R. Stradling
S.E. Craig
18.5.2 Sleep-related disorders of breathing
3261(16)
J.R. Stradling
S.E. Craig
18.6 Allergic rhinitis
3277(6)
Stephen R. Durham
Hesham Saleh
18.7 Asthma
3283(28)
A.J. Newman Taylor
Paul Cullinan
18.8 Chronic obstructive pulmonary disease
3311(34)
William MacNee
18.9 Bronchiectasis
3345(8)
D. Bilton
18.10 Cystic fibrosis
3353(12)
Andrew Bush
Caroline Elston
18.11 Diffuse parenchymal lung diseases
3365(38)
18.11.1 Diffuse parenchymal lung disease: an introduction
3365(10)
A.U. Wells
18.11.2 Idiopathic pulmonary fibrosis
3375(7)
All. Wells
AG. Nicholson
N. Hirani
18.11.3 Bronchiolitis obliterans and cryptogenic organizing pneumonia
3382(5)
A.U. Wells
Nicholas K. Harrison
18.11.4 The lung in autoimmune rheumatic disorders
3387(8)
A.U. Wells
H.R. Branley
18.11.5 The lung in vasculitis
3395(8)
A.U. Wells
Roland M. du Bois
18.12 Sarcoidosis
3403(11)
Robert P. Baughman
Elyse E. Lower
18.13 Pneumoconioses
3414(11)
A. Seaton
18.14 Miscellaneous conditions
3425(42)
18.14.1 Pulmonary haemorrhagic disorders
3425(3)
D.J. Hendrick
G.P. Spickett
18.14.2 Eosinophilic pneumonia
3428(3)
D.J. Hendrick
G.P. Spickett
18.14.3 Lymphocytic infiltrations of the lung
3431(3)
D.J. Hendrick
18.14.4 Extrinsic allergic alveolitis
3434(1)
D.J. Hendrick
G.P. Spickett
18.14.5 Pulmonary Langerhans'cell histiocytosis
3434(13)
S.J. Bourke
D.J. Hendrick
18.14.6 Lymphangioleiomyomatosis
3447(1)
S.J. Bourke
D.J. Hendrick
18.14.7 Pulmonary alveolar proteinosis
3448(3)
D.J. Hendrick
18.14.8 Pulmonary amyloidosis
3451(1)
D.J. Hendrick
18.14.9 Lipoid (lipid) pneumonia
3452(2)
D.J. Hendrick
18.14.10 Pulmonary alveolar microlithiasis
3454(2)
D.J. Hendrick
18.14.11 Toxic gases and aerosols
3456(2)
D.J. Hendrick
18.14.12 Radiation pneumonitis
3458(2)
S.J. Bourke
D.J. Hendrick
18.14.13 Drug-induced lung disease
3460(7)
S.J. Bourke
D.J. Hendrick
18.15 Chronic respiratory failure
3467(9)
P.M. A Calverley
18.16 Lung transplantation
3476(10)
K. McNeil
18.17 Pleural diseases
3486(19)
Robert J.O. Davies
Fergus V. Gleeson
Y.C. Gary Lee
18.18 Disorders of the thoracic cage and diaphragm
3505(9)
John M. Shneerson
18.19 Malignant diseases
3514(33)
18.19.1 Lung cancer
3514(19)
S.G. Spiro
18.19.2 Pulmonary metastases
3533(1)
S.G. Spiro
18.19.3 Pleural tumours
3534(5)
Robert J.O. Davies
Y.C. Gary Lee
18.19.4 Mediastinal cysts and tumours
3539(8)
Malcolm K. Benson
Robert J.O. Davies
Section 19 Rheumatological disorders
19.1 Structure and function: joints and connective tissue
3547(7)
Tim E. Cawston
19.2 Clinical presentation and diagnosis of rheumatic disease
3554(6)
Anthony S. Russell
Robert Ferrari
19.3 Clinical investigation
3560(11)
Michael Doherty
Peter C. Lanyon
19.4 Back pain and regional disorders
3571(8)
Simon Carette
19.5 Rheumatoid arthritis
3579(24)
Ravinder Nath Maini
19.6 Ankylosing spondylitis, other spondyloarthritides, and related conditions
3603(14)
J. Braun
J. Sieper
19.7 Pyogenic arthritis
3617(5)
Anthony R. Berendt
19.8 Reactive arthritis
3622(6)
J.S. Hill Gaston
19.9 Osteoarthritis
3628(9)
Paul H. Brion
Kenneth C. Kalunian
19.10 Crystal-related arthropathies
3637(12)
Edward Roddy
Michael Doherty
19.11 Autoimmune rheumatic disorders and vasculitides
3649(56)
19.11.1 Introduction
3649(3)
I.P. Giles
David A. Isenberg
19.11.2 Systemic lupus erythematosus and related disorders
3652(13)
Anisur Rahman
David A. Isenberg
19.11.3 Systemic sclerosis
3665(14)
Christopher P. Denton
Carol M. Black
19.11.4 Polymyalgia rheumatica and temporal arteritis
3679(5)
Jan Tore Gran
19.11.5 Behcet's syndrome
3684(4)
Sebahattin Yurdakul
Izzet Fresko
Hasan Yazici
19.11.6 Sjogren's syndrome
3688(4)
Patrick J.W. Venables
19.11.7 Polymyositis and dermatomyositis
3692(6)
John H. Stone
19.11.8 Kawasaki's disease
3698(7)
Brian W. McCrindle
19.12 Miscellaneous conditions presenting to the rheumatologist
3705(14)
Donncha O'Gradaigh
Index
Volume 3
Contributors xxxi
Section 20 Disorders of the skeleton
20.1 Skeletal disorders---general approach and clinical conditions
3719(52)
R. Smith
B.P. Wordsworth
20.2 Inherited defects of connective tissue: Ehlers-Danlos syndrome, Marfan's syndrome, and pseudoxanthoma elasticum
3771(17)
N.P. Burrows
20.3 Osteomyelitis
3788(8)
Anthony R. Berendt
Martin McNally
20.4 Osteoporosis
3796(6)
Juliet Compston
20.5 Osteonecrosis, osteochondrosis, and osteochondritis dissecans
3802(7)
Donncha O'Gradaigh
Adrian Crisp
Section 21 Disorders of the kidney and urinary tract
21.1 Structure and functions of the kidney
3809(8)
J. David Williams
A.O. Phillips
21.2 Electrolyte disorders
3817(29)
21.2.1 Disorders of water and sodium homeostasis
3817(14)
Steven G. Achinger
Juan Carlos Ayus
21.2.2 Disorders of potassium homeostasis
3831(15)
John D. Firth
21.3 Clinical presentation of renal disease
3846(17)
Richard E. Fielding
Ken Farrington
21.4 Clinical investigation of renal disease
3863(22)
A. Davenport
21.5 Acute kidney injury
3885(19)
John D. Firth
21.6 Chronic kidney disease
3904(26)
Eberhard Ritz
Tilman B. Drueke
John D. Firth
21.7 Renal replacement therapy
3930(41)
21.7.1 Haemodialysis
3930(13)
Ken Farrington
Roger Greenwood
21.7.2 Peritoneal dialysis
3943(4)
Simon Davies
21.7.3 Renal transplantation
3947(24)
P. Sweny
21.8 Glomerular diseases
3971(31)
21.8.1 Immunoglobulin A nephropathy and Henoch-Schonlein purpura
3971(6)
Jonathan Barratt
John Feehally
21.8.2 Thin membrane nephropathy
3977(2)
Peter Topham
John Feehally
21.8.3 Minimal-change nephropathy and focal segmental glomerulosclerosis
3979(6)
Dwomoa Adu
21.8.4 Membranous nephropathy
3985(3)
Dwomoa Adu
21.8.5 Proliferative glomerulonephritis
3988(3)
Peter W. Mathieson
21.8.6 Mesangiocapillary glomerulonephritis
3991(4)
Peter W. Mathieson
21.8.7 Antiglomerular basement membrane disease
3995(7)
Jeremy Levy
Charles Pusey
21.9 Tubulointerstitial diseases
4002(19)
21.9.1 Acute interstitial nephritis
4002(4)
Simon D. Roger
21.9.2 Chronic tubulointerstitial nephritis
4006(15)
Marc E. De Broe
Patrick C. D'Haese
Monique M. Elseviers
21.10 The kidney in systemic disease
4021(61)
21.10.1 Diabetes mellitus and the kidney
4021(11)
Rudolf Bilous
21.10.2 The kidney in systemic vasculitis
4032(12)
David Jayne
21.10.3 The kidney in rheumatological disorders
4044(11)
Wai Y. Tse
Dwomoa Adu
21.10.4 Renal involvement in plasma cell dyscrasias, immunoglobulin-based amyloidoses, and fibrillary glomerulopathies, lymphomas, leukaemias
4055(10)
P. Ronco
F. Bridoux
G. Touchard
21.10.5 Haemolytic uraemic syndrome
4065(4)
Paul Warwicker
Timothy H.J. Goodship
21.10.6 Sickle-cell disease and the kidney
4069(2)
G.R. Serjeant
21.10.7 Infection-associated nephropathies
4071(5)
A. Neil Turner
21.10.8 Malignancy-associated renal disease
4076(2)
A. Neil Turner
21.10.9 Atherosclerotic renovascular disease
4078(4)
P.A. Kalra
John D. Firth
21.11 Renal diseases in the tropics
4082(13)
Vivekanand Jha
21.12 Renal involvement in genetic disease
4095(8)
D. Joly
J.P. Grunfeld
21.13 Urinary tract infection
4103(20)
Charles Tomson
Alison Armitage
21.14 Disorders of renal calcium handling, urinary stones, and nephrocalcinosis
4123(10)
Elaine M. Worcester
Andrew P. Evan
Fredric L. Coe
21.15 The renal tubular acidoses
4133(7)
Fiona E. Karet
21.16 Disorders of tubular electrolyte handling
4140(11)
Nine V.A.M. Knoers
Elena N. Levtchenko
21.17 Urinary tract obstruction
4151(11)
Muhammad M. Yaqoob
Islam Junaid
21.18 Malignant diseases of the urinary tract
4162(12)
David Neal
21.19 Drugs and the kidney
4174(17)
Aine Burns
Caroline Ashley
Section 22 Disorders of the blood
22.1 Introduction
4191(8)
D.J. Weatherall
22.2 Haemopoietic stem cells
4199(15)
22.2.1 Stem cells and haemopoiesis
4199(9)
C.A. Sieff
22.2.2 Haemopoietic stem cell disorders
4208(6)
D.C. Linch
22.3 The leukaemias and other bone marrow disorders
4214(89)
22.3.1 Cell and molecular biology of human leukaemias
4214(7)
Alejandro Gutierrez
A. Thomas Look
22.3.2 The classification of leukaemia
4221(8)
Wendy N. Erber
22.3.3 Acute lymphoblastic leukaemia
4229(4)
Tim Eden
22.3.4 Acute myeloid leukaemia
4233(7)
Jonathan Kell
Steve Knapper
Alan Burnett
22.3.5 Chronic lymphocytic leukaemia and other leukaemias of mature B and T cells
4240(7)
Clive S. Zent
Aaron Polliack
22.3.6 Chronic myeloid leukaemia
4247(9)
Tariq I. Mughal
John M. Goldman
22.3.7 Myelodysplasia
4256(8)
Lawrence B. Gardner
Chi V. Dang
22.3.8 The polycythaemias
4264(10)
Stefan O. Ciurea
Ronald Hoffman
22.3.9 Idiopathic myelofibrosis
4274(6)
Jerry L. Spivak
22.3.10 Thrombocytosis
4280(7)
Stefan O. Ciurea
Ronald Hoffman
22.3.11 Aplastic anaemia and other causes of bone marrow failure
4287(11)
Judith C.W. Marsh
E.C. Gordon-Smith
22.3.12 Paroxysmal nocturnal haemoglobinuria
4298(5)
Lucio Luzzatto
22.4 The white cells and lymphoproliferative disorders
4303(64)
22.4.1 Leucocytes in health and disease
4303(8)
Joseph Sinning
Nancy Berliner
22.4.2 Introduction to the lymphoproliferative disorders
4311(6)
Barbara A. Degar
Nancy Berliner
22.4.3 Lymphoma
4317(17)
James O. Armitage
22.4.4 The spleen and its disorders
4334(8)
D. Swirsky
22.4.5 Myeloma and paraproteinaemias
4342(14)
Robert A. Kyle
S. Vincent Rajkumar
22.4.6 Eosinophilia
4356(5)
Peter F. Weller
22.4.7 Histiocytoses
4361(6)
D.K.H. Webb
22.5 The red cell
4367(113)
22.5.1 Erythropoiesis and the normal red cell
4367(7)
Anna Rita Migliaccio
Thalia Papayannopoulou
22.5.2 Anaemia: pathophysiology, classification, and clinical features
4374(7)
D.J. Weatherall
22.5.3 Anaemia as a challenge to world health
4381(5)
D.J. Weatherall
22.5.4 Iron metabolism and its disorders
4386(14)
Timothy M. Cox
22.5.5 Normochromic, normocytic anaemia
4400(2)
D.J. Weatherall
22.5.6 Megaloblastic anaemia and miscellaneous deficiency anaemias
4402(18)
A.V. Hoffbrand
22.5.7 Disorders of the synthesis or function of haemoglobin
4420(25)
D.J. Weatherall
22.5.8 Anaemias resulting from defective maturation of red cells
4445(5)
James S. Wiley
22.5.9 Haemolytic anaemia---congenital and acquired
4450(11)
Amy Powers
Leslie Silberstein
Frank J. Strobl
22.5.10 Disorders of the red cell membrane
4461(7)
Patrick G. Gallagher
22.5.11 Erythrocyte enzymopathies
4468(5)
Ernest Beutler
22.5.12 Glucose-6-phosphate dehydrogenase (G6PD) deficiency
4473(7)
Lucio Luzzatto
22.6 Haemostasis and thrombosis
4480(67)
22.6.1 The biology of haemostasis and thrombosis
4480(18)
Harold R. Roberts
Gilbert C. White
22.6.2 Evaluation of the patient with a bleeding tendency
4498(9)
Trevor Baglin
22.6.3 Disorders of platelet number and function
4507(11)
Kathryn E. Webert
John G. Kelton
22.6.4 Genetic disorders of coagulation
4518(13)
Eleanor S. Pollak
Katherine A. High
22.6.5 Acquired coagulation disorders
4531(16)
T.E. Warkentin
22.7 The blood in systemic disease
4547(14)
D.J. Weatherall
22.8 Blood replacement
4561(22)
22.8.1 Blood transfusion
4561(10)
P.L. Perrotta
Y. Han
EL Snyder
22.8.2 Haemopoietic stem cell transplantation
4571(12)
E.C. Gordon-Smith
Emma Morris
Section 23 Disorders of the skin
Editor. Graham S. Ogg
23.1 Structure and function of skin
4583(4)
John A. McGrath
23.2 Clinical approach to the diagnosis of skin disease
4587(6)
Vanessa Venning
23.3 Inherited skin disease
4593(9)
Irene M. Leigh
David P. Kelsell
23.4 Vesiculobullous disease
4602(8)
Fenella Wojnarowska
23.5 Papulosquamous disease
4610(8)
Christopher Griffiths
23.6 Dermatitis/eczema
4618(8)
Peter S. Friedmann
23.7 Cutaneous vasculitis, connective tissue diseases, and urticaria
4626(30)
Susan Burge
Graham S. Ogg
23.8 Disorders of pigmentation
4656(9)
Eugene Healy
23.9 Photosensitivity
4665(7)
Jane McGregor
23.10 Infections and the skin
4672(4)
Roderick J. Hay
23.11 Sebaceous and sweat gland disorders
4676(7)
Alison Layton
23.12 Blood and lymphatic vessel disorders
4683(15)
Peter S. Mortimer
23.13 Hair and nail disorders
4698(7)
David de Berker
23.14 Tumours of the skin
4705(10)
Edel O'Toole
23.15 Skin and systemic diseases
4715(9)
Clive B. Archer
23.16 Cutaneous reactions to drugs
4724(7)
Peter S. Friedmann
Eugene Healy
23.17 Management of skin disease
4731(12)
Rod Sinclair
Section 24 Neurological disorders
24.1 Introduction and approach to the patient with neurological disease
4743(3)
Alastair Compston
24.2 Mind and brain: building bridges linking neurology, psychiatry, and psychology
4746(3)
A. Zeman
24.3 Clinical investigation of neurological disease
4749(37)
24.3.1 Lumbar puncture
4749(3)
Roger A. Barker
Wendy Phillips
R. Rhys Davies
24.3.2 Electrophysiology of the central and peripheral nervous systems
4752(16)
Christian Krarup
24.3.3 Imaging in neurological diseases
4768(14)
Andrew J. Molyneux
Shelley Renowden
Marcus Bradley
24.3.4 Investigation of central motor pathways: magnetic brain stimulation
4782(4)
K.R. Mills
24.4 Higher cerebral function
4786(24)
24.4.1 Disturbances of higher cerebral function
4786(9)
Peter J. Nestor
John R. Hodges
24.4.2 Alzheimer's disease and other dementias
4795(15)
John R. Hodges
24.5 Epilepsy and disorders of consciousness
4810(41)
24.5.1 Epilepsy in later childhood and adulthood
4810(16)
G.D. Perkin
24.5.2 Narcolepsy
4826(2)
David Parkes
24.5.3 Sleep disorders
4828(10)
Paul J. Reading
24.5.4 Syncope
4838(3)
A.J. Larner
24.5.5 The unconscious patient
4841(6)
David Bates
24.5.6 Brain death and the vegetative state
4847(4)
P.J. Hutchinson
J.D. Pickard
24.6 Disorders of the special senses
4851(20)
24.6.1 Visual pathways
4851(7)
Christopher Kennard
24.6.2 Eye movements and balance
4858(7)
Michael Strupp
Thomas Brandt
24.6.3 Hearing
4865(6)
Linda M. Luxon
24.7 Disorders of movement
4871(40)
24.7.1 Subcortical structures: the cerebellum, basal ganglia, and thalamus
4871(8)
Mark J. Edwards
Penelope Talelli
24.7.2 Parkinsonism and other extrapyramidal diseases
4879(10)
K. Ray Chaudhuri
Vinod K. Metta
24.7.3 Movement disorders other than Parkinson's disease
4889(13)
Roger A. Barker
David J. Burn
24.7.4 Ataxic disorders
4902(9)
Nicholas Wood
24.8 Headache
4911(18)
Peter J. Goadsby
24.9 Brainstem syndromes
4929(4)
David Bates
24.10 Specific conditions affecting the central nervous system
4933(43)
24.10.1 Stroke: cerebrovascular disease
4933(15)
J. van Gijn
24.10.2 Demyelinating disorders of the central nervous system
4948(15)
Siddharthan Chandran
Alastair Compston
24.10.3 Traumatic injuries to the head
4963(4)
Laurence Watkins
David G.T. Thomas
24.10.4 Intracranial tumours
4967(5)
Jeremy Rees
24.10.5 Idiopathic intracranial hypertension
4972(4)
N.F. Lawton
24.11 Infections ofthe central nervous system
4976(57)
24.11.1 Bacterial infections
4976(22)
Diederik van de Beek
Jeremy Farrar
Guy E. Thwaites
24.11.2 Viral infections
4998(15)
Jeremy Farrar
Bridget Wills
Menno D. de Jong
David A. Warrell
24.11.3 Intracranial abscesses
5013(2)
T.P. Lawrence
R.S.C. Kerr
24.11.4 Neurosyphilis and neuro-AIDS
5015(8)
Hadi Manji
24.11.5 Human prion diseases
5023(10)
R.G. Will
24.12 Disorders of cranial nerves
5033(6)
R.A.C. Hughes
P.K. Thomas
24.13 Disorders of the spinal cord
5039(16)
24.13.1 Diseases of the spinal cord
5039(6)
A.J. Larner
24.13.2 Spinal cord injury and its management
5045(10)
M.P. Barnes
24.14 Diseases of the autonomic nervous system
5055(14)
Christopher J. Mathias
24.15 The motor neuron diseases
5069(7)
Michael Donaghy
24.16 Diseases of the peripheral nerves
5076(20)
R.A.C. Hughes
P.K. Thomas
24.17 Inherited neurodegenerative diseases
5096(38)
Edwin H. Kolodny
Swati Sathe
24.18 Developmental abnormalities ofthe central nervous system
5134(16)
C.M. Verity
C. Ffrench-Constant
H.V. Firth
24.19 Acquired metabolic disorders and the nervous system
5150(8)
Neil Scolding
C.D. Marsden
24.20 Neurological complications of systemic disease
5158(8)
Neil Scolding
24.21 Paraneoplastic neurological syndromes
5166(9)
Jeremy Rees
Jerry Posner
Angela Vincent
24.22 Autoimmune limbic encephalitis and Morvan's syndrome
5175(2)
Camilla Buckley
Angela Vincent
24.23 Disorders of the neuromuscular junction
5177(8)
David Hilton-Jones
Jacqueline Palace
24.24 Disorders of muscle
5185(48)
24.24.1 Structure and function of muscle
5185(5)
M.G. Hanna
24.24.2 Muscular dystrophy
5190(17)
K. Bushby
24.24.3 Myotonia
5207(5)
David Hilton-Jones
24.24.4 Metabolic and endocrine disorders
5212(9)
David Hilton-Jones
Richard Edwards
24.24.5 Mitochondrial encephalomyopathies
5221(6)
P.F. Chinnery
D.M. Turnbull
24.24.6 Primary (tropical) pyomyositis
5227(6)
David A. Warrell
Section 25 The eye
25.1 The eye in general medicine
5233(24)
Peggy Frith
Section 26 Psychiatry and drug related problems
26.1 General introduction
5257(2)
Michael Sharpe
26.2 Taking a psychiatric history from a medical patient
5259(4)
Eleanor Feldman
26.3 Acute behavioural emergencies
5263(5)
Eleanor Feldman
26.4 Neuropsychiatric disorders
5268(16)
Mervi L.S. Pitkanen
Tom Stevens
Michael D. Kopelman
26.5 Psychiatric disorders as they concern the physician
5284(45)
26.5.1 Grief, stress, and post-traumatic stress disorder
5284(8)
Tim Dalgleish
Jenny Yiend
Ann-Marie J. Golden
26.5.2 The patient who has attempted suicide
5292(4)
Keith Hawton
26.5.3 Medically unexplained symptoms in patients attending medical clinics
5296(8)
Michael Sharpe
26.5.4 Chronic fatigue syndrome (postviral fatigue syndrome, neurasthenia, and myalgic encephalomyelitis)
5304(4)
Michael Sharpe
26.5.5 Anxiety and depression
5308(9)
Lydia Chwastiak
Wayne J. Katon
26.5.6 Eating disorders
5317(7)
Christopher G. Fairburn
26.5.7 Schizophrenia, bipolar disorder, obsessive-compulsive disorder, and personality disorder
5324(5)
Stephen Lawrie
26.6 Psychiatric treatments
5329(12)
26.6.1 Psychopharmacology in medical practice
5329(9)
Philip J. Cowen
26.6.2 Psychological treatment in medical practice
5338(3)
Michael Sharpe
Simon Wessely
26.7 Alcohol and drug-related problems
5341(18)
26.7.1 Alcohol and drug dependence
5341(10)
Mary E. McCauL
Gary S. Wand
Yngvild K. Olsen
26.7.2 Brief interventions against excessive alcohol consumption
5351(8)
Nick Heather
Eileen Kaner
Section 27 Forensic medicine
27.1 Forensic medicine and the practising doctor
5359(16)
Anthony Busuttil
Section 28 Sports medicine
28.1 Sports and exercise medicine
5375(14)
Roger L. Wolman
Section 29 Geratology
29.1 Medicine in old age
5389(17)
Gordon Wilcock
Kenneth Rockwood
29.2 Mental disorders of old age
5406(5)
Robin Jacoby
Section 30 Pain
30.1 Dealing with pain
5411(8)
Henry McQuay
Section 31 Palliative medicine
31.1 Palliative care
5419(14)
Bee Wee
Section 32 Biochemistry in medicine
32.1 Biochemistry in medicine---reference intervals: the use of biochemical analysis for diagnosis and management
5433(20)
P. Holloway
Heather Stoddart
Section 33 Acute medicine
33.1 Acute medical presentations
5453(57)
John D. Firth
David A. Warrell
Timothy M. Cox
33.2 Practical procedures
5510
John D. Firth
David A. Warrell
Timothy M. Cox
Index