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Contributors |
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xxxi | |
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Section 1 On being a patient |
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3 | (6) |
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Section 2 Modern medicine: foundations, achievements, and limitations |
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2.1 Scientific background to medicine |
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9 | (7) |
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2.1.1 Science in medicine: when, how, and what |
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9 | (3) |
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2.1.2 Evolution: medicine's most basic science |
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12 | (4) |
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16 | (6) |
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2.3 Evidence-based medicine |
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22 | (26) |
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2.3.1 Bringing the best evidence to the point of care |
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22 | (5) |
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2.3.2 Evidence-based medicine---does it apply to my particular patient? |
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27 | (4) |
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2.3.3 Large-scale randomized evidence: trials and meta-analyses of trials |
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31 | (14) |
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2.3.4 The future of clinical trials |
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45 | (3) |
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2.4 Funding of health care |
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48 | (17) |
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2.4.1 The evaluation and provision of effective medicines |
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48 | (6) |
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2.4.2 Reasonableness and its definition in the provision of health care |
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54 | (4) |
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2.4.3 Priority setting in developed and developing countries |
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58 | (2) |
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2.4.4 Sustaining innovation in an era of specialized medicine |
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60 | (5) |
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2.5 Complementary and alternative medicine |
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65 | (8) |
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Section 3 Global patterns of disease and medical practice |
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3.1 Global burden of disease: causes, levels, and intervention strategies |
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73 | (7) |
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3.2 Human population size, environment, and health |
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80 | (6) |
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3.3 Avoiding disease and promoting health |
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86 | (1) |
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3.3.1 Preventive medicine |
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80 | (6) |
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3.3 Avoiding disease and promoting health |
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86 | (1) |
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3.3.1 Preventive medicine |
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80 | (6) |
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3.3 Avoiding disease and promoting health |
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86 | (26) |
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3.3.1 Preventive medicine |
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86 | (8) |
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94 | (14) |
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3.3.3 The importance of mass communication in promoting positive health |
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108 | (4) |
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112 | (7) |
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3.4.1 The cost of health care in Western countries |
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112 | (4) |
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3.4.2 A sinister pathogen corrupts two disciplines: the demographic entrapment of Middle Africa |
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116 | (3) |
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119 | (8) |
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127 | (8) |
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135 | (17) |
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4.2.1 The human genome sequence |
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135 | (1) |
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4.2.2 The genomic basis of medicine |
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136 | (16) |
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152 | (8) |
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4.4 Ion channels and disease |
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160 | (9) |
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4.5 Intracellular signalling |
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169 | (8) |
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4.6 Apoptosis in health and disease |
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177 | (12) |
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4.7 Discovery of embryonic stem cells and the concept of regenerative medicine |
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189 | (4) |
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4.8 Stem cells and regenerative medicine |
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193 | (14) |
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Section 5 Immunological mechanisms |
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5.1 Structure and function |
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207 | (28) |
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5.1.1 The innate immune system |
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207 | (6) |
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5.1.2 The complement system |
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213 | (11) |
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224 | (11) |
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235 | (23) |
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258 | (9) |
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267 | (13) |
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5.5 Principles of transplantation immunology |
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280 | (19) |
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Section 6 Principles of clinical oncology |
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6.1 Epidemiology of cancer |
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299 | (34) |
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6.2 The nature and development of cancer |
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333 | (25) |
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6.3 The genetics of inherited cancers |
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358 | (14) |
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6.4 Cancer immunity and clinical oncology |
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372 | (8) |
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6.5 Cancer: clinical features and management |
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380 | (16) |
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6.6 Cancer chemotherapy and radiation therapy |
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396 | (13) |
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7.1 Pathogenic microorganisms and the host |
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409 | (11) |
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7.1.1 Biology of pathogenic microorganisms |
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409 | (4) |
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7.1.2 Physiological changes, clinical features, and general management of infected patients |
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413 | (7) |
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7.2 The patient with suspected infection |
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420 | (40) |
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420 | (3) |
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7.2.2 Fever of unknown origin |
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423 | (5) |
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7.2.3 Nosocomial infections |
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428 | (3) |
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7.2.4 Infection in the immunocompromised host |
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431 | (10) |
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7.2.5 Antimicrobial chemotherapy |
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441 | (19) |
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460 | (5) |
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7.4 Travel and expedition medicine |
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465 | (7) |
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472 | (526) |
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7.5.1 Respiratory tract viruses |
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473 | (9) |
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7.5.2 Herpesviruses (excluding Epstein-Barr virus) |
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482 | (19) |
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501 | (7) |
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508 | (5) |
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7.5.5 Mumps: epidemic parotitis |
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513 | (2) |
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515 | (10) |
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7.5.7 Nipah and Hendra virus encephalitides |
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525 | (2) |
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7.5.8 Enterovirus infections |
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527 | (9) |
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7.5.9 Virus infections causing diarrhoea and vomiting |
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536 | (5) |
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7.5.10 Rhabdoviruses: rabies and rabies-related lyssaviruses |
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541 | (14) |
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7.5.11 Colorado tick fever and other arthropod-borne reoviruses |
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555 | (2) |
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557 | (4) |
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561 | (3) |
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7.5.14 Flaviviruses excluding dengue |
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564 | (11) |
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575 | (4) |
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579 | (9) |
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588 | (7) |
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595 | (5) |
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7.5.19 Papillomaviruses and polyomaviruses |
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600 | (7) |
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607 | (2) |
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7.5.21 Hepatitis viruses (excluding hepatitis C virus) |
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609 | (6) |
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615 | (5) |
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620 | (24) |
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7.5.24 HIV in the developing world |
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644 | (6) |
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7.5.25 HTLV-1, HTLV-2, and associated diseases |
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650 | (3) |
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7.5.26 Viruses and cancer |
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653 | (2) |
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655 | (2) |
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7.5.28 Molluscum contagiosum |
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657 | (2) |
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7.5.29 Newly discovered viruses |
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659 | (4) |
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663 | (1) |
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664 | (6) |
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7.6.2 Streptococci and enterococci |
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670 | (9) |
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7.6.3 Pneumococcal infections |
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679 | (14) |
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693 | (16) |
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7.6.5 Meningococcal infections |
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709 | (13) |
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7.6.6 Neisseria gonorrhoeae |
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722 | (5) |
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727 | (1) |
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7.6.7.1 Enterobacteria and bacterial food poisoning |
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727 | (8) |
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7.6.7.2 Pseudomonas aeruginosa |
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735 | (3) |
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7.6.8 Typhoid and paratyphoid fevers |
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738 | (7) |
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7.6.9 Intracellular klebsiella infections (donovanosis and rhinoscleroma) |
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745 | (3) |
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7.6.10 Anaerobic bacteria |
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748 | (6) |
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754 | (5) |
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7.6.12 Haemophilus influenzae |
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759 | (4) |
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7.6.13 Haemophilus ducreyi and chancroid |
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763 | (1) |
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7.6.14 Bordetella infection |
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764 | (4) |
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7.6.15 Melioidosis and glanders |
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768 | (4) |
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7.6.16 Plague: Yersinia pestis |
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772 | (4) |
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7.6.17 Other Yersinia infections: yersiniosis |
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776 | (1) |
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777 | (3) |
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7.6.19 Francisella tularensis infection |
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780 | (3) |
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783 | (6) |
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789 | (6) |
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795 | (5) |
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7.6.23 Clostridium difficile |
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800 | (3) |
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7.6.24 Botulism, gas gangrene, and clostridial gastrointestinal infections |
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803 | (7) |
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810 | (21) |
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7.6.26 Disease caused by environmental mycobacteria |
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831 | (5) |
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7.6.27 Leprosy (Hansen's disease) |
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836 | (12) |
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7.6.28 Buruli ulcer: Mycobacterium ulcerans infection |
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848 | (2) |
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850 | (6) |
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856 | (1) |
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857 | (3) |
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860 | (6) |
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866 | (8) |
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874 | (5) |
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7.6.35 Nonvenereal endemic treponematoses: yaws, endemic syphilis (bejel), and pinta |
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879 | (6) |
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885 | (11) |
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896 | (3) |
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7.6.38 Legionellosis and legionnaires' disease |
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899 | (4) |
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903 | (16) |
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919 | (4) |
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7.6.41 Coxiella burnetii infections (Q fever) |
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923 | (3) |
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7.6.42 Bartonellas excluding B. bacilliformis |
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926 | (8) |
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7.6.43 Bartonella bacilliformis infection |
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934 | (5) |
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7.6.44 Chlamydial infections |
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939 | (11) |
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950 | (11) |
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7.6.46 A check list of bacteria associated with infection in humans |
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961 | (37) |
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998 | (37) |
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998 | (20) |
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1018 | (2) |
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1020 | (3) |
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7.7.4 Paracoccidioidomycosis |
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1023 | (5) |
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7.7.5 Pneumocystis jirovecii |
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1028 | (4) |
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7.7.6 Penicillium marneffei infection |
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1032 | (3) |
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1035 | (110) |
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1035 | (10) |
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1045 | (44) |
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1089 | (1) |
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1090 | (8) |
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7.8.5 Cryptosporidium and cryptosporidiosis |
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1098 | (7) |
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7.8.6 Cyclospora and cyclosporiasis |
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1105 | (4) |
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7.8.7 Sarcocystosis (sarcosporidiosis) |
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1109 | (2) |
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7.8.8 Giardiasis, balantidiasis, isosporiasis, and microsporidiosis |
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1111 | (7) |
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7.8.9 Blastocystis hominis infection |
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1118 | (1) |
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7.8.10 Human African trypanosomiasis |
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1119 | (8) |
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1127 | (7) |
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1134 | (8) |
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1142 | (3) |
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7.9 Nematodes (roundworms) |
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1145 | (40) |
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7.9.1 Cutaneous filariasis |
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1145 | (8) |
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7.9.2 Lymphatic filariasis |
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1153 | (7) |
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7.9.3 Guinea worm disease (dracunculiasis) |
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1160 | (3) |
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7.9.4 Strongyloidiasis, hookworm, and other gut strongyloid nematodes |
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1163 | (5) |
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7.9.5 Gut and tissue nematode infections acquired by ingestion |
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1168 | (11) |
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7.9.6 Parastrongyliasis (angiostrongyliasis) |
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1179 | (3) |
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1182 | (3) |
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7.10 Cestodes (tapeworms) |
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1185 | (17) |
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7.10.1 Cystic hydatid disease (Echinococcus granulosus) |
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1185 | (3) |
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7.10.2 Cyclophyllidian gut tapeworms |
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1188 | (5) |
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1193 | (6) |
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7.10.4 Diphyllobothriasis and sparganosis |
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1199 | (3) |
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1202 | (23) |
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1202 | (10) |
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7.11.2 Liver fluke infections |
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1212 | (4) |
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7.11.3 Lung flukes (paragonimiasis) |
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1216 | (3) |
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7.11.4 Intestinal trematode infections |
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1219 | (6) |
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7.12 Nonvenomous arthropods |
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1225 | (12) |
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7.13 Pentastomiasis (porocephalosis, linguatulosis/ linguatuliasis) |
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1237 | (6) |
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Section 8 Sexually transmitted diseases and sexual health |
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8.1 Epidemiology of sexually transmitted infections |
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1243 | (7) |
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1250 | (3) |
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8.3 Sexual history and examination |
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1253 | (3) |
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1256 | (3) |
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8.5 Pelvic inflammatory disease |
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1259 | (3) |
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8.6 Principles of contraception |
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1262 | (9) |
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Section 9 Chemical and physical injuries and environmental factors and disease |
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9.1 Poisoning by drugs and chemicals |
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1271 | (53) |
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9.2 Injuries, envenoming, poisoning, and allergic reactions caused by animals |
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1324 | (37) |
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9.3 Injuries, poisoning, and allergic reactions caused by plants |
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1361 | (15) |
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9.3.1 Poisonous plants and fungi |
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1361 | (10) |
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9.3.2 Common Indian poisonous plants |
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1371 | (5) |
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9.4 Occupational and environmental health and safety |
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1376 | (17) |
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9.4.1 Occupational and environmental health |
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1376 | (12) |
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9.4.2 Occupational safety |
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1388 | (5) |
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9.5 Environmental diseases |
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1393 | (56) |
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1393 | (2) |
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1395 | (2) |
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1397 | (5) |
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9.5.4 Diseases of high terrestrial altitudes |
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1402 | (6) |
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1408 | (8) |
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1416 | (6) |
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9.5.7 Lightning and electrical injuries |
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1422 | (4) |
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9.5.8 Podoconiosis (nonfilarial elephantiasis) |
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1426 | (3) |
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1429 | (3) |
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1432 | (1) |
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1432 | (4) |
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9.5.12 Disasters: earthquakes, volcanic eruptions, hurricanes, and floods |
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1436 | (4) |
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1440 | (9) |
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Section 10 Clinical pharmacology |
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10.1 Principles of clinical pharmacology and drug therapy |
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1449 | (30) |
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11.1 Nutrition: macronutrient metabolism |
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1479 | (8) |
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11.2 Vitamins and trace elements |
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1487 | (18) |
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1505 | (10) |
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11.4 Diseases of ovemourished societies and the need for dietary change |
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1515 | (12) |
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1527 | (8) |
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11.6 Artifical nutrition support |
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1535 | (14) |
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Section 12 Metabolic disorders |
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12.1 The inborn errors of metabolism: general aspects |
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1549 | (10) |
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12.2 Protein-dependent inborn errors of metabolism |
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1559 | (37) |
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12.3 Disorders of carbohydrate metabolism |
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1596 | (23) |
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12.3.1 Glycogen storage diseases |
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1596 | (8) |
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12.3.2 Inborn errors of fructose metabolism 1604 |
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1604 | (6) |
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12.3.3 Disorders of galactose, pentose, and pyruvate metabolism |
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1610 | (9) |
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12.4 Disorders of purine and pyrimidine metabolism |
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1619 | (17) |
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1636 | (16) |
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12.6 Lipid and lipoprotein disorders |
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1652 | (21) |
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12.7 Trace metal disorders |
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1673 | (21) |
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12.7.1 Hereditary haemochromatosis |
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1673 | (15) |
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12.7.2 Inherited diseases of copper metabolism: Wilson's disease and Menkes' disease |
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1688 | (6) |
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1694 | (25) |
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12.9 Disorders of peroxisomal metabolism in adults |
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1719 | |
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12.10 Hereditary disorders of oxalate metabolism-the primary hyperoxalurias |
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1730 | (308) |
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12.11 Disturbances of acid-base homeostasis |
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1738 | (14) |
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12.12 The acute phase response, amyloidoses and familial Mediterranean fever |
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1752 | (28) |
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12.12.1 The acute phase response and Creactive protein |
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1752 | (8) |
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12.12.2 Hereditary periodic fever syndromes |
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1760 | (6) |
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1766 | (14) |
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12.13 α1 Antitrypsin deficiency and the serpinopathies |
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1780 | (7) |
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Index |
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Contributors |
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xxxi | |
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Section 13 Endocrine disorders |
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13.1 Principles of hormone action |
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|
1787 | (12) |
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13.2 Disorders of the anterior pituitary gland |
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1799 | (20) |
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13.3 Disorders of the posterior pituitary gland |
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1819 | (7) |
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13.4 The thyroid gland and disorders of thyroid function |
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1826 | (19) |
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1845 | (6) |
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13.6 Parathyroid disorders and diseases altering calcium metabolism |
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1851 | (18) |
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1869 | (32) |
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13.7.1 Disorders of the adrenal cortex |
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1869 | (22) |
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13.7.2 Congenital adrenal hyperplasia |
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|
1891 | (10) |
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13.8 The reproductive system |
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1901 | (47) |
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1901 | (12) |
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13.8.2 Disorders of male reproduction |
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1913 | (15) |
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|
1928 | (12) |
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13.8.4 Benign breast disease |
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|
1940 | (2) |
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13.8.5 Sexual dysfunction |
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1942 | (6) |
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13.9 Disorders of growth and development |
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1948 | (28) |
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13.9.1 Normal growth and its disorders |
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1948 | (10) |
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1958 | (5) |
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|
|
13.9.3 Normal and abnormal sexual differentiation |
|
|
1963 | (13) |
|
|
13.10 Pancreatic endocrine disorders and multiple endocrine neoplasia |
|
|
1976 | (11) |
|
|
|
13.11 Disorders of glucose homeostasis |
|
|
1987 | (72) |
|
|
1987 | (62) |
|
|
|
|
2049 | (10) |
|
|
13.12 Hormonal manifestations of nonendocrine disease |
|
|
2059 | (11) |
|
|
|
13.13 The pineal gland and melatonin |
|
|
2070 | (5) |
|
|
|
Section 14 Medical disorders in pregnancy |
|
|
|
14.1 Physiological changes of normal pregnancy |
|
|
2075 | (4) |
|
|
14.2 Nutrition in pregnancy |
|
|
2079 | (6) |
|
|
14.3 Medical management of normal pregnancy |
|
|
2085 | (8) |
|
|
14.4 Hypertension in pregnancy |
|
|
2093 | (10) |
|
|
14.5 Renal disease in pregnancy |
|
|
2103 | (5) |
|
|
14.6 Heart disease in pregnancy |
|
|
2108 | (8) |
|
|
14.7 Thrombosis in pregnancy |
|
|
2116 | (5) |
|
|
14.8 Chest diseases in pregnancy |
|
|
2121 | (4) |
|
|
|
14.9 Liver and gastrointestinal diseases in pregnancy |
|
|
2125 | (8) |
|
|
14.10 Diabetes in pregnancy |
|
|
2133 | (7) |
|
|
|
14.11 Endocrine disease in pregnancy |
|
|
2140 | (4) |
|
|
14.12 Neurological disease in pregnancy |
|
|
2144 | (5) |
|
|
|
14.13 The skin in pregnancy |
|
|
2149 | (5) |
|
|
14.14 Autoimmune rheumatic disorders and vasculitis in pregnancy |
|
|
2154 | (11) |
|
|
|
14.15 Infections in pregnancy |
|
|
2165 | (8) |
|
|
14.16 Blood disorders specific to pregnancy |
|
|
2173 | (8) |
|
|
|
14.17 Malignant disease in pregnancy |
|
|
2181 | (5) |
|
|
14.18 Prescribing in pregnancy |
|
|
2186 | (5) |
|
|
14.19 Benefits and risks of oral contraception |
|
|
2191 | (5) |
|
|
14.20 Benefits and risks of hormone replacement therapy |
|
|
2196 | (5) |
|
|
Section 15 Gastroenterological disorders |
|
|
|
15.1 Structure and function of the gut |
|
|
2201 | (4) |
|
|
15.2 Symptomatology of gastrointestinal disease |
|
|
2205 | (5) |
|
|
15.3 Methods for investigation of gastrointestinal disease |
|
|
2210 | (22) |
|
15.3.1 Colonoscopy and flexible sigmoidoscopy |
|
|
2210 | (4) |
|
|
|
15.3.2 Upper gastrointestinal endoscopy |
|
|
2214 | (5) |
|
|
15.3.3 Radiology of the gastrointestinal tract |
|
|
2219 | (7) |
|
|
15.3.4 Investigation of gastrointestinal function |
|
|
2226 | (6) |
|
|
15.4 Common acute abdominal presentations |
|
|
2232 | (12) |
|
|
2232 | (5) |
|
|
15.4.2 Gastrointestinal bleeding |
|
|
2237 | (7) |
|
|
|
15.5 Immune disorders of the gastrointestinal tract |
|
|
2244 | (13) |
|
|
15.6 The mouth and salivary glands |
|
|
2257 | (30) |
|
|
|
15.7 Diseases of the oesophagus |
|
|
2287 | (18) |
|
|
15.8 Peptic ulcer disease |
|
|
2305 | (11) |
|
|
15.9 Hormones and the gastrointestinal tract |
|
|
2316 | (10) |
|
|
|
|
|
|
2326 | (35) |
|
15.10.1 Differential diagnosis and investigation of malabsorption |
|
|
2326 | (4) |
|
|
15.10.2 Small bowel bacterial overgrowth |
|
|
2330 | (5) |
|
|
|
2335 | (7) |
|
|
|
15.10.4 Gastrointestinal lymphoma |
|
|
2342 | (5) |
|
|
15.10.5 Disaccharidase deficiency |
|
|
2347 | (5) |
|
|
15.10.6 Whipple's disease |
|
|
2352 | (2) |
|
|
15.10.7 Effects of massive small bowel resection |
|
|
2354 | (3) |
|
|
15.10.8 Malabsorption syndromes in the tropics |
|
|
2357 | (4) |
|
|
|
2361 | (10) |
|
|
|
2371 | (13) |
|
|
15.13 Irritable bowel syndrome and functional bowel disorders |
|
|
2384 | (5) |
|
|
15.14 Colonic diverticular disease |
|
|
2389 | (6) |
|
|
|
|
15.15 Congenital abnormalities of the gastrointestinal tract |
|
|
2395 | (10) |
|
|
|
15.16 Cancers of the gastrointestinal tract |
|
|
2405 | (12) |
|
|
|
15.17 Vascular and collagen disorders |
|
|
2417 | (7) |
|
|
15.18 Gastrointestinal infections |
|
|
2424 | (11) |
|
|
|
15.19 Structure and function of the liver, biliary tract, and pancreas |
|
|
2435 | (9) |
|
|
|
|
2444 | (8) |
|
|
15.21 Hepatitis and autoimmune liver disease |
|
|
2452 | (22) |
|
15.21.1 Viral hepatitis-clinical aspects |
|
|
2452 | (8) |
|
|
15.21.2 Autoimmune hepatitis |
|
|
2460 | (4) |
|
|
15.21.3 Primary biliary cirrhosis |
|
|
2464 | (4) |
|
|
15.21.4 Primary sclerosing cholangitis |
|
|
2468 | (6) |
|
|
15.22 Other disorders of the liver |
|
|
2474 | (72) |
|
15.22.1 Alcoholic liver disease |
|
|
2474 | (6) |
|
|
|
15.22.2 Nonalcoholic steatohepatitis |
|
|
2480 | (2) |
|
|
|
15.22.3 Cirrhosis and ascites |
|
|
2482 | (11) |
|
|
15.22.4 Hepatocellular failure |
|
|
2493 | (12) |
|
|
15.22.5 Liver transplantation |
|
|
2505 | (7) |
|
|
|
|
15.22.6 Liver tumours---primary and secondary |
|
|
2512 | (11) |
|
|
|
15.22.7 Hepatic granulomas |
|
|
2523 | (4) |
|
|
|
|
|
15.22.8 Drugs and liver damage |
|
|
2527 | (10) |
|
|
15.22.9 The liver in systemic disease |
|
|
2537 | (9) |
|
|
15.23 Diseases of the gallbladder and biliary tree |
|
|
2546 | (11) |
|
|
15.24 Diseases of the pancreas |
|
|
2557 | (22) |
|
15.24.1 Acute pancreatitis |
|
|
2557 | (10) |
|
|
|
15.24.2 Chronic pancreatitis |
|
|
2567 | (7) |
|
|
15.24.3 Tumours of the pancreas |
|
|
2574 | (5) |
|
|
|
15.25 Congenital disorders of the liver, biliary tract, and pancreas |
|
|
2579 | (5) |
|
|
15.26 Miscellaneous disorders of the bowel and liver |
|
|
2584 | (9) |
|
|
Section 16 Cardiovascular disorders |
|
|
|
16.1 Structure and function |
|
|
2593 | (35) |
|
16.1.1 Blood vessels and the endothelium |
|
|
2593 | (10) |
|
|
16.1.2 Cardiac myocytes and the cardiac action potential |
|
|
2603 | (15) |
|
|
|
|
|
|
16.1.3 Clinical physiology of the normal heart |
|
|
2618 | (10) |
|
|
16.2 Clinical presentation of heart disease |
|
|
2628 | (15) |
|
16.2.1 Chest pain, breathlessness, and fatigue |
|
|
2628 | (8) |
|
|
16.2.2 Syncope and palpitations |
|
|
2636 | (7) |
|
|
|
|
16.3 Clinical investigation of cardiac disorders |
|
|
2643 | (45) |
|
16.3.1 Electrocardiography |
|
|
2643 | (19) |
|
|
|
|
2662 | (9) |
|
|
|
16.3.3 Cardiac investigation---nuclear and other imaging techniques |
|
|
2671 | (7) |
|
|
|
16.3.4 Cardiac catheterization and angiography |
|
|
2678 | (10) |
|
|
|
2688 | (29) |
|
|
|
|
|
2717 | (19) |
|
16.5.1 Clinical features and medical treatments |
|
|
2717 | (12) |
|
|
|
16.5.2 Cardiac transplantation and mechanical circulatory support |
|
|
2729 | (7) |
|
|
|
2736 | (22) |
|
|
16.7 Diseases of heart muscle |
|
|
2758 | (32) |
|
|
2758 | (6) |
|
|
16.7.2 The cardiomyopathies: hypertrophic, dilated, restrictive, and right ventricular |
|
|
2764 | (18) |
|
|
|
16.7.3 Specific heart muscle disorders |
|
|
2782 | (8) |
|
|
|
|
2790 | (7) |
|
|
16.9 Cardiac involvement in infectious disease |
|
|
2797 | (33) |
|
16.9.1 Acute rheumatic fever |
|
|
2797 | (9) |
|
|
16.9.2 Infective endocarditis |
|
|
2806 | (16) |
|
|
16.9.3 Cardiac disease in HIV infectiont |
|
|
2822 | (4) |
|
|
16.9.4 Cardiovascular syphilis |
|
|
2826 | (4) |
|
|
16.10 Tumours of the heart |
|
|
2830 | (4) |
|
|
16.11 Cardiac involvement in genetic disease |
|
|
2834 | (8) |
|
|
16.12 Congenital heart disease in the adult |
|
|
2842 | (31) |
|
|
16.13 Coronary heart disease |
|
|
2873 | (80) |
|
16.13.1 Biology and pathology of atherosclerosis |
|
|
2873 | (8) |
|
|
|
16.13.2 Coronary heart disease: epidemiology and prevention |
|
|
2881 | (17) |
|
|
|
16.13.3 Influences acting in utero and in early childhood |
|
|
2898 | (4) |
|
|
16.13.4 Management of stable angina |
|
|
2902 | (9) |
|
|
16.13.5 Management of acute coronary syndrome |
|
|
2911 | (24) |
|
|
16.13.6 Percutaneous interventional cardiac procedures |
|
|
2935 | (7) |
|
|
16.13.7 Coronary artery bypass surgery |
|
|
2942 | (4) |
|
|
16.13.8 The impact of coronary heart disease on life and work |
|
|
2946 | (7) |
|
|
16.14 Diseases of the arteries |
|
|
2953 | (21) |
|
16.14.1 Thoracic aortic dissection |
|
|
2953 | (6) |
|
|
|
16.14.2 Peripheral arterial disease |
|
|
2959 | (7) |
|
|
|
16.14.3 Cholesterol embolism |
|
|
2966 | (2) |
|
|
16.14.4 Takayasu's arteritis |
|
|
2968 | (6) |
|
|
16.15 The pulmonary circulation |
|
|
2974 | (28) |
|
16.15.1 Structure and function |
|
|
2974 | (4) |
|
|
16.15.2 Pulmonary hypertension |
|
|
2978 | (14) |
|
|
|
2992 | (10) |
|
|
|
16.16 Venous thromboembolism |
|
|
3002 | (21) |
|
16.16.1 Deep venous thrombosis and pulmonary embolism |
|
|
3002 | (16) |
|
|
|
16.16.2 Therapeutic anticoagulation |
|
|
3018 | (5) |
|
|
|
3023 | (60) |
|
16.17.1 Essential hypertension---definition, epidemiology, and pathophysiology |
|
|
3023 | (16) |
|
|
16.17.2 Diagnosis, assessment, and treatment of essential hypertension |
|
|
3039 | (18) |
|
|
16.17.3 Secondary hypertension |
|
|
3057 | (14) |
|
|
16.17.4 Mendelian disorders causing hypertension |
|
|
3071 | (3) |
|
|
16.17.5 Hypertensive urgencies and emergencies |
|
|
3074 | (9) |
|
|
|
16.18 Chronic peripheral oedema and lymphoedema |
|
|
3083 | (10) |
|
|
16.19 Idiopathic oedema of women |
|
|
3093 | (4) |
|
|
Section 17 Critical care medicine |
|
|
|
|
3097 | (9) |
|
|
|
|
|
3106 | (9) |
|
|
17.3 The clinical approach to the patient who is very ill |
|
|
3115 | (7) |
|
|
17.4 Circulation and circulatory support in the critically ill |
|
|
3122 | (10) |
|
|
17.5 Acute respiratory failure |
|
|
3132 | (15) |
|
|
|
17.6 Management of raised intracranial pressure |
|
|
3147 | (6) |
|
|
17.7 Sedation and analgesia in the critically ill |
|
|
3153 | (5) |
|
|
|
17.8 Discontinuing treatment of the critically ill patient |
|
|
3158 | (3) |
|
|
17.9 Brainstem death and organ donation |
|
|
3161 | (8) |
|
|
Section 18 Respiratory disorders |
|
|
|
18.1 Structure and function |
|
|
3169 | (13) |
|
18.1.1 The upper respiratory tract |
|
|
3169 | (4) |
|
|
|
18.1.2 Airways and alveoli |
|
|
3173 | (9) |
|
|
18.2 The clinical presentation of respiratory disease |
|
|
3182 | (7) |
|
|
18.3 Clinical investigation of respiratory disorders |
|
|
3189 | (38) |
|
18.3.1 Respiratory function tests |
|
|
3189 | (11) |
|
|
|
3200 | (16) |
|
|
|
18.3.3 Bronchoscopy, thoracoscopy, and tissue biopsy |
|
|
3216 | (11) |
|
|
18.4 Respiratory infection |
|
|
3227 | (27) |
|
18.4.1 Upper respiratory tract infections |
|
|
3227 | (4) |
|
|
18.4.2 Pneumonia in the normal host |
|
|
3231 | (12) |
|
|
18.4.3 Nosocomial pneumonia |
|
|
3243 | (3) |
|
|
18.4.4 Pulmonary complications of HIV infection |
|
|
3246 | (8) |
|
|
18.5 The upper respiratory tract |
|
|
3254 | (23) |
|
18.5.1 Upper airways obstruction |
|
|
3254 | (7) |
|
|
|
18.5.2 Sleep-related disorders of breathing |
|
|
3261 | (16) |
|
|
|
|
3277 | (6) |
|
|
|
|
3283 | (28) |
|
|
|
18.8 Chronic obstructive pulmonary disease |
|
|
3311 | (34) |
|
|
|
3345 | (8) |
|
|
|
3353 | (12) |
|
|
|
18.11 Diffuse parenchymal lung diseases |
|
|
3365 | (38) |
|
18.11.1 Diffuse parenchymal lung disease: an introduction |
|
|
3365 | (10) |
|
|
18.11.2 Idiopathic pulmonary fibrosis |
|
|
3375 | (7) |
|
|
|
|
18.11.3 Bronchiolitis obliterans and cryptogenic organizing pneumonia |
|
|
3382 | (5) |
|
|
|
18.11.4 The lung in autoimmune rheumatic disorders |
|
|
3387 | (8) |
|
|
|
18.11.5 The lung in vasculitis |
|
|
3395 | (8) |
|
|
|
|
3403 | (11) |
|
|
|
|
3414 | (11) |
|
|
18.14 Miscellaneous conditions |
|
|
3425 | (42) |
|
18.14.1 Pulmonary haemorrhagic disorders |
|
|
3425 | (3) |
|
|
|
18.14.2 Eosinophilic pneumonia |
|
|
3428 | (3) |
|
|
|
18.14.3 Lymphocytic infiltrations of the lung |
|
|
3431 | (3) |
|
|
18.14.4 Extrinsic allergic alveolitis |
|
|
3434 | (1) |
|
|
|
18.14.5 Pulmonary Langerhans'cell histiocytosis |
|
|
3434 | (13) |
|
|
|
18.14.6 Lymphangioleiomyomatosis |
|
|
3447 | (1) |
|
|
|
18.14.7 Pulmonary alveolar proteinosis |
|
|
3448 | (3) |
|
|
18.14.8 Pulmonary amyloidosis |
|
|
3451 | (1) |
|
|
18.14.9 Lipoid (lipid) pneumonia |
|
|
3452 | (2) |
|
|
18.14.10 Pulmonary alveolar microlithiasis |
|
|
3454 | (2) |
|
|
18.14.11 Toxic gases and aerosols |
|
|
3456 | (2) |
|
|
18.14.12 Radiation pneumonitis |
|
|
3458 | (2) |
|
|
|
18.14.13 Drug-induced lung disease |
|
|
3460 | (7) |
|
|
|
18.15 Chronic respiratory failure |
|
|
3467 | (9) |
|
|
18.16 Lung transplantation |
|
|
3476 | (10) |
|
|
|
3486 | (19) |
|
|
|
|
18.18 Disorders of the thoracic cage and diaphragm |
|
|
3505 | (9) |
|
|
|
3514 | (33) |
|
|
3514 | (19) |
|
|
18.19.2 Pulmonary metastases |
|
|
3533 | (1) |
|
|
|
3534 | (5) |
|
|
|
18.19.4 Mediastinal cysts and tumours |
|
|
3539 | (8) |
|
|
|
Section 19 Rheumatological disorders |
|
|
|
19.1 Structure and function: joints and connective tissue |
|
|
3547 | (7) |
|
|
19.2 Clinical presentation and diagnosis of rheumatic disease |
|
|
3554 | (6) |
|
|
|
19.3 Clinical investigation |
|
|
3560 | (11) |
|
|
|
19.4 Back pain and regional disorders |
|
|
3571 | (8) |
|
|
19.5 Rheumatoid arthritis |
|
|
3579 | (24) |
|
|
19.6 Ankylosing spondylitis, other spondyloarthritides, and related conditions |
|
|
3603 | (14) |
|
|
|
|
3617 | (5) |
|
|
|
3622 | (6) |
|
|
|
3628 | (9) |
|
|
|
19.10 Crystal-related arthropathies |
|
|
3637 | (12) |
|
|
|
19.11 Autoimmune rheumatic disorders and vasculitides |
|
|
3649 | (56) |
|
|
3649 | (3) |
|
|
|
19.11.2 Systemic lupus erythematosus and related disorders |
|
|
3652 | (13) |
|
|
|
19.11.3 Systemic sclerosis |
|
|
3665 | (14) |
|
|
|
19.11.4 Polymyalgia rheumatica and temporal arteritis |
|
|
3679 | (5) |
|
|
19.11.5 Behcet's syndrome |
|
|
3684 | (4) |
|
|
|
|
19.11.6 Sjogren's syndrome |
|
|
3688 | (4) |
|
|
19.11.7 Polymyositis and dermatomyositis |
|
|
3692 | (6) |
|
|
19.11.8 Kawasaki's disease |
|
|
3698 | (7) |
|
|
19.12 Miscellaneous conditions presenting to the rheumatologist |
|
|
3705 | (14) |
|
Index |
|
|
|
Contributors |
|
xxxi | |
|
Section 20 Disorders of the skeleton |
|
|
|
20.1 Skeletal disorders---general approach and clinical conditions |
|
|
3719 | (52) |
|
|
|
20.2 Inherited defects of connective tissue: Ehlers-Danlos syndrome, Marfan's syndrome, and pseudoxanthoma elasticum |
|
|
3771 | (17) |
|
|
|
3788 | (8) |
|
|
|
|
3796 | (6) |
|
|
20.5 Osteonecrosis, osteochondrosis, and osteochondritis dissecans |
|
|
3802 | (7) |
|
|
|
Section 21 Disorders of the kidney and urinary tract |
|
|
|
21.1 Structure and functions of the kidney |
|
|
3809 | (8) |
|
|
|
21.2 Electrolyte disorders |
|
|
3817 | (29) |
|
21.2.1 Disorders of water and sodium homeostasis |
|
|
3817 | (14) |
|
|
|
21.2.2 Disorders of potassium homeostasis |
|
|
3831 | (15) |
|
|
21.3 Clinical presentation of renal disease |
|
|
3846 | (17) |
|
|
|
21.4 Clinical investigation of renal disease |
|
|
3863 | (22) |
|
|
|
3885 | (19) |
|
|
21.6 Chronic kidney disease |
|
|
3904 | (26) |
|
|
|
|
21.7 Renal replacement therapy |
|
|
3930 | (41) |
|
|
3930 | (13) |
|
|
|
21.7.2 Peritoneal dialysis |
|
|
3943 | (4) |
|
|
21.7.3 Renal transplantation |
|
|
3947 | (24) |
|
|
|
3971 | (31) |
|
21.8.1 Immunoglobulin A nephropathy and Henoch-Schonlein purpura |
|
|
3971 | (6) |
|
|
|
21.8.2 Thin membrane nephropathy |
|
|
3977 | (2) |
|
|
|
21.8.3 Minimal-change nephropathy and focal segmental glomerulosclerosis |
|
|
3979 | (6) |
|
|
21.8.4 Membranous nephropathy |
|
|
3985 | (3) |
|
|
21.8.5 Proliferative glomerulonephritis |
|
|
3988 | (3) |
|
|
21.8.6 Mesangiocapillary glomerulonephritis |
|
|
3991 | (4) |
|
|
21.8.7 Antiglomerular basement membrane disease |
|
|
3995 | (7) |
|
|
|
21.9 Tubulointerstitial diseases |
|
|
4002 | (19) |
|
21.9.1 Acute interstitial nephritis |
|
|
4002 | (4) |
|
|
21.9.2 Chronic tubulointerstitial nephritis |
|
|
4006 | (15) |
|
|
|
|
21.10 The kidney in systemic disease |
|
|
4021 | (61) |
|
21.10.1 Diabetes mellitus and the kidney |
|
|
4021 | (11) |
|
|
21.10.2 The kidney in systemic vasculitis |
|
|
4032 | (12) |
|
|
21.10.3 The kidney in rheumatological disorders |
|
|
4044 | (11) |
|
|
|
21.10.4 Renal involvement in plasma cell dyscrasias, immunoglobulin-based amyloidoses, and fibrillary glomerulopathies, lymphomas, leukaemias |
|
|
4055 | (10) |
|
|
|
|
21.10.5 Haemolytic uraemic syndrome |
|
|
4065 | (4) |
|
|
|
21.10.6 Sickle-cell disease and the kidney |
|
|
4069 | (2) |
|
|
21.10.7 Infection-associated nephropathies |
|
|
4071 | (5) |
|
|
21.10.8 Malignancy-associated renal disease |
|
|
4076 | (2) |
|
|
21.10.9 Atherosclerotic renovascular disease |
|
|
4078 | (4) |
|
|
|
21.11 Renal diseases in the tropics |
|
|
4082 | (13) |
|
|
21.12 Renal involvement in genetic disease |
|
|
4095 | (8) |
|
|
|
21.13 Urinary tract infection |
|
|
4103 | (20) |
|
|
|
21.14 Disorders of renal calcium handling, urinary stones, and nephrocalcinosis |
|
|
4123 | (10) |
|
|
|
|
21.15 The renal tubular acidoses |
|
|
4133 | (7) |
|
|
21.16 Disorders of tubular electrolyte handling |
|
|
4140 | (11) |
|
|
|
21.17 Urinary tract obstruction |
|
|
4151 | (11) |
|
|
|
21.18 Malignant diseases of the urinary tract |
|
|
4162 | (12) |
|
|
21.19 Drugs and the kidney |
|
|
4174 | (17) |
|
|
|
Section 22 Disorders of the blood |
|
|
|
|
4191 | (8) |
|
|
22.2 Haemopoietic stem cells |
|
|
4199 | (15) |
|
22.2.1 Stem cells and haemopoiesis |
|
|
4199 | (9) |
|
|
22.2.2 Haemopoietic stem cell disorders |
|
|
4208 | (6) |
|
|
22.3 The leukaemias and other bone marrow disorders |
|
|
4214 | (89) |
|
22.3.1 Cell and molecular biology of human leukaemias |
|
|
4214 | (7) |
|
|
|
22.3.2 The classification of leukaemia |
|
|
4221 | (8) |
|
|
22.3.3 Acute lymphoblastic leukaemia |
|
|
4229 | (4) |
|
|
22.3.4 Acute myeloid leukaemia |
|
|
4233 | (7) |
|
|
|
|
22.3.5 Chronic lymphocytic leukaemia and other leukaemias of mature B and T cells |
|
|
4240 | (7) |
|
|
|
22.3.6 Chronic myeloid leukaemia |
|
|
4247 | (9) |
|
|
|
|
4256 | (8) |
|
|
|
22.3.8 The polycythaemias |
|
|
4264 | (10) |
|
|
|
22.3.9 Idiopathic myelofibrosis |
|
|
4274 | (6) |
|
|
|
4280 | (7) |
|
|
|
22.3.11 Aplastic anaemia and other causes of bone marrow failure |
|
|
4287 | (11) |
|
|
|
22.3.12 Paroxysmal nocturnal haemoglobinuria |
|
|
4298 | (5) |
|
|
22.4 The white cells and lymphoproliferative disorders |
|
|
4303 | (64) |
|
22.4.1 Leucocytes in health and disease |
|
|
4303 | (8) |
|
|
|
22.4.2 Introduction to the lymphoproliferative disorders |
|
|
4311 | (6) |
|
|
|
|
4317 | (17) |
|
|
22.4.4 The spleen and its disorders |
|
|
4334 | (8) |
|
|
22.4.5 Myeloma and paraproteinaemias |
|
|
4342 | (14) |
|
|
|
|
4356 | (5) |
|
|
|
4361 | (6) |
|
|
|
4367 | (113) |
|
22.5.1 Erythropoiesis and the normal red cell |
|
|
4367 | (7) |
|
|
|
22.5.2 Anaemia: pathophysiology, classification, and clinical features |
|
|
4374 | (7) |
|
|
22.5.3 Anaemia as a challenge to world health |
|
|
4381 | (5) |
|
|
22.5.4 Iron metabolism and its disorders |
|
|
4386 | (14) |
|
|
22.5.5 Normochromic, normocytic anaemia |
|
|
4400 | (2) |
|
|
22.5.6 Megaloblastic anaemia and miscellaneous deficiency anaemias |
|
|
4402 | (18) |
|
|
22.5.7 Disorders of the synthesis or function of haemoglobin |
|
|
4420 | (25) |
|
|
22.5.8 Anaemias resulting from defective maturation of red cells |
|
|
4445 | (5) |
|
|
22.5.9 Haemolytic anaemia---congenital and acquired |
|
|
4450 | (11) |
|
|
|
|
22.5.10 Disorders of the red cell membrane |
|
|
4461 | (7) |
|
|
22.5.11 Erythrocyte enzymopathies |
|
|
4468 | (5) |
|
|
22.5.12 Glucose-6-phosphate dehydrogenase (G6PD) deficiency |
|
|
4473 | (7) |
|
|
22.6 Haemostasis and thrombosis |
|
|
4480 | (67) |
|
22.6.1 The biology of haemostasis and thrombosis |
|
|
4480 | (18) |
|
|
|
22.6.2 Evaluation of the patient with a bleeding tendency |
|
|
4498 | (9) |
|
|
22.6.3 Disorders of platelet number and function |
|
|
4507 | (11) |
|
|
|
22.6.4 Genetic disorders of coagulation |
|
|
4518 | (13) |
|
|
|
22.6.5 Acquired coagulation disorders |
|
|
4531 | (16) |
|
|
22.7 The blood in systemic disease |
|
|
4547 | (14) |
|
|
|
4561 | (22) |
|
|
4561 | (10) |
|
|
|
|
22.8.2 Haemopoietic stem cell transplantation |
|
|
4571 | (12) |
|
|
|
Section 23 Disorders of the skin |
|
|
|
|
23.1 Structure and function of skin |
|
|
4583 | (4) |
|
|
23.2 Clinical approach to the diagnosis of skin disease |
|
|
4587 | (6) |
|
|
23.3 Inherited skin disease |
|
|
4593 | (9) |
|
|
|
23.4 Vesiculobullous disease |
|
|
4602 | (8) |
|
|
23.5 Papulosquamous disease |
|
|
4610 | (8) |
|
|
|
4618 | (8) |
|
|
23.7 Cutaneous vasculitis, connective tissue diseases, and urticaria |
|
|
4626 | (30) |
|
|
|
23.8 Disorders of pigmentation |
|
|
4656 | (9) |
|
|
|
4665 | (7) |
|
|
23.10 Infections and the skin |
|
|
4672 | (4) |
|
|
23.11 Sebaceous and sweat gland disorders |
|
|
4676 | (7) |
|
|
23.12 Blood and lymphatic vessel disorders |
|
|
4683 | (15) |
|
|
23.13 Hair and nail disorders |
|
|
4698 | (7) |
|
|
23.14 Tumours of the skin |
|
|
4705 | (10) |
|
|
23.15 Skin and systemic diseases |
|
|
4715 | (9) |
|
|
23.16 Cutaneous reactions to drugs |
|
|
4724 | (7) |
|
|
|
23.17 Management of skin disease |
|
|
4731 | (12) |
|
|
Section 24 Neurological disorders |
|
|
|
24.1 Introduction and approach to the patient with neurological disease |
|
|
4743 | (3) |
|
|
24.2 Mind and brain: building bridges linking neurology, psychiatry, and psychology |
|
|
4746 | (3) |
|
|
24.3 Clinical investigation of neurological disease |
|
|
4749 | (37) |
|
|
4749 | (3) |
|
|
|
|
24.3.2 Electrophysiology of the central and peripheral nervous systems |
|
|
4752 | (16) |
|
|
24.3.3 Imaging in neurological diseases |
|
|
4768 | (14) |
|
|
|
|
24.3.4 Investigation of central motor pathways: magnetic brain stimulation |
|
|
4782 | (4) |
|
|
24.4 Higher cerebral function |
|
|
4786 | (24) |
|
24.4.1 Disturbances of higher cerebral function |
|
|
4786 | (9) |
|
|
|
24.4.2 Alzheimer's disease and other dementias |
|
|
4795 | (15) |
|
|
24.5 Epilepsy and disorders of consciousness |
|
|
4810 | (41) |
|
24.5.1 Epilepsy in later childhood and adulthood |
|
|
4810 | (16) |
|
|
|
4826 | (2) |
|
|
|
4828 | (10) |
|
|
|
4838 | (3) |
|
|
24.5.5 The unconscious patient |
|
|
4841 | (6) |
|
|
24.5.6 Brain death and the vegetative state |
|
|
4847 | (4) |
|
|
|
24.6 Disorders of the special senses |
|
|
4851 | (20) |
|
|
4851 | (7) |
|
|
24.6.2 Eye movements and balance |
|
|
4858 | (7) |
|
|
|
|
4865 | (6) |
|
|
24.7 Disorders of movement |
|
|
4871 | (40) |
|
24.7.1 Subcortical structures: the cerebellum, basal ganglia, and thalamus |
|
|
4871 | (8) |
|
|
|
24.7.2 Parkinsonism and other extrapyramidal diseases |
|
|
4879 | (10) |
|
|
|
24.7.3 Movement disorders other than Parkinson's disease |
|
|
4889 | (13) |
|
|
|
|
4902 | (9) |
|
|
|
4911 | (18) |
|
|
|
4929 | (4) |
|
|
24.10 Specific conditions affecting the central nervous system |
|
|
4933 | (43) |
|
24.10.1 Stroke: cerebrovascular disease |
|
|
4933 | (15) |
|
|
24.10.2 Demyelinating disorders of the central nervous system |
|
|
4948 | (15) |
|
|
|
24.10.3 Traumatic injuries to the head |
|
|
4963 | (4) |
|
|
|
24.10.4 Intracranial tumours |
|
|
4967 | (5) |
|
|
24.10.5 Idiopathic intracranial hypertension |
|
|
4972 | (4) |
|
|
24.11 Infections ofthe central nervous system |
|
|
4976 | (57) |
|
24.11.1 Bacterial infections |
|
|
4976 | (22) |
|
|
|
|
|
4998 | (15) |
|
|
|
|
|
24.11.3 Intracranial abscesses |
|
|
5013 | (2) |
|
|
|
24.11.4 Neurosyphilis and neuro-AIDS |
|
|
5015 | (8) |
|
|
24.11.5 Human prion diseases |
|
|
5023 | (10) |
|
|
24.12 Disorders of cranial nerves |
|
|
5033 | (6) |
|
|
|
24.13 Disorders of the spinal cord |
|
|
5039 | (16) |
|
24.13.1 Diseases of the spinal cord |
|
|
5039 | (6) |
|
|
24.13.2 Spinal cord injury and its management |
|
|
5045 | (10) |
|
|
24.14 Diseases of the autonomic nervous system |
|
|
5055 | (14) |
|
|
24.15 The motor neuron diseases |
|
|
5069 | (7) |
|
|
24.16 Diseases of the peripheral nerves |
|
|
5076 | (20) |
|
|
|
24.17 Inherited neurodegenerative diseases |
|
|
5096 | (38) |
|
|
|
24.18 Developmental abnormalities ofthe central nervous system |
|
|
5134 | (16) |
|
|
|
|
24.19 Acquired metabolic disorders and the nervous system |
|
|
5150 | (8) |
|
|
|
24.20 Neurological complications of systemic disease |
|
|
5158 | (8) |
|
|
24.21 Paraneoplastic neurological syndromes |
|
|
5166 | (9) |
|
|
|
|
24.22 Autoimmune limbic encephalitis and Morvan's syndrome |
|
|
5175 | (2) |
|
|
|
24.23 Disorders of the neuromuscular junction |
|
|
5177 | (8) |
|
|
|
24.24 Disorders of muscle |
|
|
5185 | (48) |
|
24.24.1 Structure and function of muscle |
|
|
5185 | (5) |
|
|
24.24.2 Muscular dystrophy |
|
|
5190 | (17) |
|
|
|
5207 | (5) |
|
|
24.24.4 Metabolic and endocrine disorders |
|
|
5212 | (9) |
|
|
|
24.24.5 Mitochondrial encephalomyopathies |
|
|
5221 | (6) |
|
|
|
24.24.6 Primary (tropical) pyomyositis |
|
|
5227 | (6) |
|
|
|
|
25.1 The eye in general medicine |
|
|
5233 | (24) |
|
|
Section 26 Psychiatry and drug related problems |
|
|
|
26.1 General introduction |
|
|
5257 | (2) |
|
|
26.2 Taking a psychiatric history from a medical patient |
|
|
5259 | (4) |
|
|
26.3 Acute behavioural emergencies |
|
|
5263 | (5) |
|
|
26.4 Neuropsychiatric disorders |
|
|
5268 | (16) |
|
|
|
|
26.5 Psychiatric disorders as they concern the physician |
|
|
5284 | (45) |
|
26.5.1 Grief, stress, and post-traumatic stress disorder |
|
|
5284 | (8) |
|
|
|
|
26.5.2 The patient who has attempted suicide |
|
|
5292 | (4) |
|
|
26.5.3 Medically unexplained symptoms in patients attending medical clinics |
|
|
5296 | (8) |
|
|
26.5.4 Chronic fatigue syndrome (postviral fatigue syndrome, neurasthenia, and myalgic encephalomyelitis) |
|
|
5304 | (4) |
|
|
26.5.5 Anxiety and depression |
|
|
5308 | (9) |
|
|
|
|
5317 | (7) |
|
|
26.5.7 Schizophrenia, bipolar disorder, obsessive-compulsive disorder, and personality disorder |
|
|
5324 | (5) |
|
|
26.6 Psychiatric treatments |
|
|
5329 | (12) |
|
26.6.1 Psychopharmacology in medical practice |
|
|
5329 | (9) |
|
|
26.6.2 Psychological treatment in medical practice |
|
|
5338 | (3) |
|
|
|
26.7 Alcohol and drug-related problems |
|
|
5341 | (18) |
|
26.7.1 Alcohol and drug dependence |
|
|
5341 | (10) |
|
|
|
|
26.7.2 Brief interventions against excessive alcohol consumption |
|
|
5351 | (8) |
|
|
|
Section 27 Forensic medicine |
|
|
|
27.1 Forensic medicine and the practising doctor |
|
|
5359 | (16) |
|
|
Section 28 Sports medicine |
|
|
|
28.1 Sports and exercise medicine |
|
|
5375 | (14) |
|
|
|
|
|
5389 | (17) |
|
|
|
29.2 Mental disorders of old age |
|
|
5406 | (5) |
|
|
|
|
|
5411 | (8) |
|
|
Section 31 Palliative medicine |
|
|
|
|
5419 | (14) |
|
|
Section 32 Biochemistry in medicine |
|
|
|
32.1 Biochemistry in medicine---reference intervals: the use of biochemical analysis for diagnosis and management |
|
|
5433 | (20) |
|
|
|
Section 33 Acute medicine |
|
|
|
33.1 Acute medical presentations |
|
|
5453 | (57) |
|
|
|
|
33.2 Practical procedures |
|
|
5510 | |
|
|
|
Index |
|