Section I Clinical Manifestations of Disease General Clinical Genetics 2(4) Urs Giger Hyperthermia and Hypothermia 6(4) James B. Miller Weakness and Syncope 10(7) Stephen J. Ettinger Acute Vision Loss 17(3) Susan A. McLaughlin Holly L. Hamilton Pain: Identification 20(3) Spencer A. Johnston Pain: Management 23(3) Elizabeth M. Hardie Skin and Subcutaneous The Skin as a Sensor of Internal Medical Disorders 26(3) Stephen D. White Alopecia 29(2) Gail A. Kunkle Pruritus 31(5) Peter J. Ihrke Cutaneous and Subcutaneous Lumps, Bumps and Masses 36(3) D.N. Carlotti Erosions and Ulcerations 39(4) Ian S. Mason Pustules and Papules 43(4) Edmund J. Rosser, Jr. Scaling and Crusting Dermatoses 47(4) Anthony A. Stannard Andrea G. Cannon Thierry Olivry Diagnostic Cytology of Skin Lesions 51(4) George P. Reppas Paul J. Canfield Changes in Pigmentation 55(3) Zeineb Alhaidari External Parasites: Identification and Control 58(4) Karen L. Campbell Subcutaneous Space Accumulations 62(4) David Feldman Red Eye 66(4) Joan Dziezyc Physique Obesity 70(2) Karen J. Wolfsheimer Cachexia 72(2) Deborah S. Greco Failure to Grow 74(3) Sherri L. Ihle Swollen Joints and Lameness 77(3) Michael L. Magne Urogenital Vaginal and Preputial Discharge 80(5) Hans-Klaus Dreier Polyuria and Polydipsia 85(4) Susan Meric Taylor Incontinence, Enuresis, Dysuria, and Nocturia 89(4) George E. Lees Urinary Obstruction and Functional Urine Retention 93(3) India F. Lane Discolored Urine 96(4) Joseph W. Bartges Proteinuria 100(2) Donald R. Krawiec Gastrointestinal-Abdominal Anorexia 102(2) William E. Monroe Polyphagia 104(3) Ellen N. Behrend Ptyalism 107(4) Linda J. DeBowes Gagging 111(3) Mark J. Kopit Dysphagia and Regurgitation 114(3) Christine C. Jenkins Vomiting 117(4) David C. Twedt Diarrhea 121(5) Todd R. Tams Melena and Hematochezia 126(3) W. Grant Guilford Constipation, Tenesmus, Dyschezia, and Fecal Incontinence 129(6) Brent Jones Flatulence and Borborygmus 135(2) W. Grant Guilford Abdominal Distention, Ascites, and Peritonitis 137(2) Stephen A. Kruth Neurologic Shivering and Trembling 139(3) David Lipsitz Anne E. Chauvet Ataxia, Paresis, and Paralysis 142(2) Joane Parent Altered States of Consciousness: Coma and Stupor 144(4) Linda Shell Seizures 148(4) Andree D. Quesnel Sleep Disorders 152(4) Joan C. Hendricks Behavioral Disorders 156(2) Ilana R. Reisner Katherine A. Houpt Cardiothoracic Coughing 158(8) Stephen J. Ettinger Dyspnea and Tachypnea 166(4) Grant H. Turnwald Abnormal Heart Sounds and Heart Murmurs 170(4) Wendy A. Ware Pulse Alterations 174(5) John-Karl Goodwin Hypertension 179(4) Meryl P. Littman Hypotension 183(3) Douglass K. Macintire Pleural Effusion 186(3) Kenneth J. Drobatz Cardiopulmonary Arrest and Resuscitation 189(5) mary Anna Labato Sneezing and Nasal Discharge 194(4) Brendan C. McKiernan Hematologic-Chemical Anemia 198(5) Kenita S. Rogers Polycythemia 203(3) Andreas H. Hasler Urs Giger Cyanosis 206(4) Rebecca L. Stepien Jaundice 210(3) Jan Rothuizen Bleeding Disorders: Epistaxis and Hemoptysis 213(5) Orla Mahony Petechiae and Ecchymoses 218(4) Mary Beth Callan Hyponatremia and Hypokalemia 222(5) Yonatan Peres Hyperkalemia and Hypernatremia 227(5) Michael Schaer Abnormalities of Magnesium, Calcium, and Chloride 232(4) Lisa K. Kurosky Section II Dietary Considerations of Systemic Problems Nutrition of Healthy Dogs and Cats in Various Stages of Adult Life 236(5) James G. Morris Quinton R. Rogers Neonatal and Pediatric Nutrition 241(4) Johnny D. Hoskins Developmental Orthopedic Disease of Dogs 245(6) Daniel C. Richardson Steven C. Zicker Adverse Reactions to Foods: Allergies Versus Intolerance 251(7) Philip Roudebush W. Grant Guilford Nutritional Management of Gastrointestinal, Hepatic, and Endocrine Diseases 258(4) Kathryn E. Michel Dietary Modifications in Cardiac Disease 262(7) Stephen J. Ettinger Dietary Considerations for Urinary Diseases 269(6) Scott A. Brown Joseph W. Bartges Delmar R. Finco Cathy A. Brown Jeanne A. Barsanti Enteral and Parenteral Nutritional Support 275(8) Stanley L. Marks Hyperlipidemias 283(11) John E. Bauer Section III Therapeutic Considerations in Medicine Principles of Drug Therapy 294(7) Dawn Merton Boothe Antimicrobial Drugs 301(6) Mark G. Papich Glucocorticoid Therapy 307(11) John M. MacDonald Over-the-Counter Pharmaceuticals 318(2) Etienne Cote Adverse Drug Reactions 320(5) Jill Maddison Fluid Therapy, Electrolytes, and Acid-Base Control 325(23) Rebecca Kirby Elke Rudloff Blood Banking and Transfusion Medicine 348(9) Ann E. Hohenhaus Toxicology 357(6) Steven S. Nicholson Common Plant Toxicities 363(3) Lynn Hovda Acupuncture in Small Animal Practice 366(8) Luc A.A. Janssens Complementary/Alternative Cancer Therapy-Fact or Fiction? 374(8) Gregory K. Ogilvie Narda G. Robinson Section IV Infectious Disease Frequently Asked Questions About Zoonoses 382(8) Michael G. Groves Kathleen S. Harrington Joseph Taboada Bacterial Diseases 390(10) Craig E. Greene The Rickettsioses 400(8) Edward B. Breitschwerdt Protozoal and Miscellaneous Infections 408(10) Michael R. Lappin Canine Viral Diseases 418(6) Johnny D. Hoskins FeLV and Non-Neoplastic FeLV-related Disease 424(9) Julie K. Levy FIV and FIV-related Diseases 433(5) Margaret C. Barr Tom R. Phillips FIP-related Disease 438(6) Rosalind Gaskell Susan Dawson Other Feline Viral Diseases 444(9) Alice M. Wolf Systemic Mycoses 453(25) Joseph Taboada Section V Cancer Tumor Biology 478(6) Cheryl London Principles of Chemotherapy 484(5) Antony S. Moore Angela E. Frimberger Practical Radiation Therapy 489(9) Alain Theon Paraneoplastic Syndromes 498(9) Gregory K. Ogilvie Hematopoietic Tumors 507(16) David M. Vail Tumors of the Skin 523(6) Susan A. Kraegel Bruce R. Madewell Soft Tissue Sarcomas and Hemangiosarcomas 529(6) Rodney L. Page Donald E. Thrall Bone and Joint Tumors 535(6) Rodney C. Straw Tumors of the Urogenital System and Mammary Glands 541(7) Deborah W. Knapp David J. Waters Bradley R. Schmidt Section VI The Nervous System Neurologic Manifestations of Systemic Disease 548(4) Michael Podell Diseases of the Brain 552(51) William R. Fenner Multifocal Neurologic Disease 603(5) Rodney S. bagley Diseases of the Spinal Cord 608(49) Richard A. LeCouteur Jacqueline L. Grandy Neuro-Ophthalmology-Pupils That Teach 657(5) B. Keith Collins Peripheral Nerve Disorders 662(22) Karen Dyer Inzana Disorders of the Skeletal Muscles 684(8) Stephane Blot Section VII The Cardiovascular System Pathophysiology of Heart Failure and Clinical Evaluation of Cardiac Function 692(21) Helio Autran de Morais Therapy of Heart Failure 713(24) Mark D. Kittleson Congenital Heart Disease 737(50) D. David Sisson William P. Thomas John D. Bonagura Acquired Valvular Heart Disease 787(13) Clarence Kvart Jens Haggstrom Electrocardiography 800(34) Stephen J. Ettinger Gerard Le Bobinnec Etienne Cote Echocardiography 834(40) John D. Bonagura Virginia Luis Fuentes Primary Myocardial Disease in the Dog 874(22) D. David Sisson William P. Thomas Bruce W. Keene Feline Cardiomyopathies 896(27) Philip R. Fox Pericardial Disorders 923(14) Matthew W. Miller D. David Sisson Dirofilariasis in Dogs and Cats 937(27) Ray Dillon Peripheral Vascular Disease 964 Philip R. Fox Jean-Paul Petrie Peter F. Suter Index i