Muutke küpsiste eelistusi

Particle Overload In The Rat Lung And Lung Cancer: Implications For Human Risk Assessment [Kõva köide]

Edited by
  • Formaat: Hardback, 298 pages, kõrgus x laius: 254x178 mm, kaal: 708 g
  • Ilmumisaeg: 03-Jun-1996
  • Kirjastus: Taylor & Francis Inc
  • ISBN-10: 1560325437
  • ISBN-13: 9781560325437
Teised raamatud teemal:
  • Kõva köide
  • Hind: 193,60 €*
  • * saadame teile pakkumise kasutatud raamatule, mille hind võib erineda kodulehel olevast hinnast
  • See raamat on trükist otsas, kuid me saadame teile pakkumise kasutatud raamatule.
  • Kogus:
  • Lisa ostukorvi
  • Tasuta tarne
  • Lisa soovinimekirja
Particle Overload In The Rat Lung And Lung Cancer: Implications For Human Risk AssessmentSuurem pilt
  • Formaat: Hardback, 298 pages, kõrgus x laius: 254x178 mm, kaal: 708 g
  • Ilmumisaeg: 03-Jun-1996
  • Kirjastus: Taylor & Francis Inc
  • ISBN-10: 1560325437
  • ISBN-13: 9781560325437
Teised raamatud teemal:
Püsilink: https://www.kriso.ee/db/9781560325437.html
Märksõnad:
Recent inhalation toxicology studies suggest that when laboratory rats are exposed to inorganic particles to the point that lung overload occurs, both benign and malignant tumours may develop. The significance of these results for estimating human risk, however, is unclear.; Originally published as a special issue of the journal "Inhalation Toxicology", the contributions to this volume are derived from a symposium held in March, 1995, by the Environmental Medical Service of the Massachusetts Institute of Technology. Topics addressed include epidemiology, the pathology of lung tumours, maximum tolerated doses in inhalation toxicology studies, risk assessment, the extrapolation of results from animal studies to humans, current modelling techniques and regulatory concerns.
PREFACE vii Joe L. Mauderly Robert J. McCunney, Editors LUNG OVERLOAD: THE DILEMMA AND OPPORTUNITIES FOR RESOLUTION 1(28) Joe L. Mauderly FROM THE LAB BENCH TO THE WORKPLACE: IMPLICATIONS OF TOXICOLOGY STUDIES ON OCCUPATIONAL MEDICAL PRACTICE 29(12) Robert J. McCunney EPIDEMIOLOGIC STUDIES IN NORTH AMERICAN CARBON BLACK WORKERS 41(10) James M. Robertson COMPARATIVE RESPONSE TO LONG-TERM PARTICLE EXPOSURE AMONG RATS, MICE, AND HAMSTERS 51(22) Uwe Heinrich SIGNIFICANCE OF PARTICLE PARAMETERS IN THE EVALUATION OF EXPOSURE-DOSE-RESPONSE RELATIONSHIPS OF INHALED PARTICLE 73(18) Gunter Oberdorster CURRENT INFORMATION ON LUNG OVERLOAD IN NONRODENT MAMMALS: CONTRAST WITH RATS 91(20) Morris Burton Snipes MAXIMUM TOLERATED DOSE IN PARTICULATE INHALATION STUDIES: A PATHOLOGISTS POINT OF VIEW 111(14) Ernest E. McConnell DIFFERENCES BETWEEN RODENTS AND HUMANS IN LUNG TUMOR RESPONSE--LESSONS FROM RECENT STUDIES WITH CARBON BLACK 125(14) Leonard S. Levy ROLE OF INFLAMMATION IN THE DEVELOPMENT OF RAT LUNG TUMORS IN RESPONSE TO CHRONIC PARTICLE EXPOSURE 139(16) Kevin E. Driscoll PROLONGED CELLULAR PROLIFERATION AND PULMONARY INFLAMMATION ARE PRODUCED IN RATS INHALING HIGH CONCENTRATIONS OF LOW-TOXICITY INSOLUBLE PARTICULATES: COMPARISONS WITH CYTOTOXIC DUSTS 155(14) D. B. Warheit J. F. Hansen I. S. Yuen S. I. Snajdr M. A. Hartsky EVALUATION OF THE CARCINOGENIC RISK OF BIOCHEMICALLY INERT INSOLUBLE PARTICLES BY THE EPA USING RAT INHALATION DATA 169(12) William E. Pepelko USE OF HAZARD AND RISK INFORMATION IN RISK MANAGEMENT DECISIONS: SOLID PARTICLES AND FIBERS UNDER EPAS TSCA AND EPCRA 181(12) Vanessa T. Vu LUNG CANCER IN RATS FROM PROLONGED EXPOSURE TO HIGH CONCENTRATIONS OF CARBONACEOUS PARTICLES: IMPLICATIONS FOR HUMAN RISK ASSESSMENT 193(34) Roger O. McClellan PARTICLE-INDUCED LUNG TUMORS IN RATS: EVIDENCE FOR SPECIES SPECIFICITY IN MECHANISMS 227(32) Ann Y. Watson Peter A. Valberg SELECTION OF MODELS FOR ASSESSING DOSE-RESPONSE RELATIONSHIPS FOR PARTICLE-INDUCED LUNG CANCER 259(20) Chao W. Chen Gunter Oberdorster EXTRAPOLATION MODELING OF PARTICLE DEPOSITION AND RETENTION FROM RATS TO HUMANS 279(14) C. P. Yu INDEX 293