Particle Separation Techniques: Fundamentals, Instrumentation, and Selected Applications presents the latest research in the field of particle separation methods. This edited book authored by subject specialists is logically organized in sections, grouping the separation techniques according to their preparative or analytical purposes and the particle type. Along with the traditional and classical separation methods suitable for micronic particles, an update survey of techniques appropriate for nanoparticle characterization is presented. This book fills the gap in the literature of particle suspension analysis of a synthetic but comprehensive manual, helping the reader to identify and apply selected techniques.
It provides an overview of the techniques available to a reader who is not an expert on particle separation yet about to enter the field, design an experiment, or buy an instrument for his/her new lab.
- Presents a resource that is ideal for anyone preparing samples across a variety of fields, including pharmaceuticals, food science, pollution analysis and control, agricultural products, and more
- Includes real case examples discussed by leading experts in the field
- Provides chapters that contain a unique, common table that summarizes points-of-strength and the weaknesses of each technique
Part 1: Introduction 1. Introduction - The new, latest improvements in the particle separation techniques
2. What is a particle, classification and properties
3. Particle dispersions in liquid media
4. Particle characterization: parameters and selected methods
Part 2: Preparative separations
5. Membrane-based filtration technology
6. Sedimentation
7. Electrophoresis and dielectrophoresis
8. Magnetic Separations (MS)
9. Historical overview of flow cytometry and frontier applications
10. Affinity Chromatography
11. Affinity separation on fibers and surfaces Part 3: Analytical separations
12. Production, role and use of reference materials for nanoparticle characterization
13. Size exclusion chormatography (SEC)
14. Passive and active microfluidic separation methods
15. Inertial microfluidic techniques
16. Analytical ultracentrifugation
17. Centrifugal liquid sedimentation methods
18. Theoretical principles of field-flow fractionation and SPLITT
19. Field flow fractionation (FFF): practical and experimental aspects
20. Capillar electromigration techniques
Part 4: Present Challenges
21. Regulatory and technical challenges in the size characterization of nanoparticulate systems
Catia Contado is an associate professor of Analytical Chemistry at the University of Ferrara, where she currently teaches analytical chemistry, analytical techniques for characterizing nano- and micro-structured materials, and quality assurance for pharmaceutical industries. She earned a PhD in analytical and environmental chemistry at the University of Ferrara but she carried out her research at the Water Studies Centre of Monash University (Melbourne, AU) and at the Field Flow Fractionation Research Center of University of Utah (UT, USA). In 2006, as Fulbright Fellow, she worked at the Lerner Research Centre - Cleveland Clinic (OH, USA). Her research interests include the development of analytical methods for the analysis of micro and nanomaterials of natural and industrial origin, contained in pharmaceutical, food and consumer products.