Details information on the preformulation of drugs, formulation using quality by design (QbD) principles, and characterization of parenteral microemulsions for drug delivery. Explores the role of surfactants and cosurfactants in formulation, clinical aspects of parenteral microemulsion, regulatory perspectives and patents, etc.
Parenteral delivery of hydrophobic drugs is a challenging task. Research on exploiting newer approaches
to make the delivery of pharmaceuticals by nondigestive tracts effective yet safe and cost effective shows
that microemulsion is one such approach for parenteral delivery. This new book provides systematic
information regarding the preformulation of drugs, formulation using quality by design (QbD) principles,
and characterization of parenteral microemulsions for drug delivery. The book explores specific aspects
of microemulsions such as the role of surfactants and cosurfactants in formulation, clinical aspects of
parenteral microemulsion, regulatory perspectives and patents, as well as future challenges in this field
of research.
Arvustused
Covers important aspects of parenteral microemulsions, ranging from formulation to characterization, highlighting parenteral pharmaceutical applications, including clinical and regulatory aspectsboth prerequisites for successful product developments for the benefit of patients. We are confident this book will stimulate further research in parenteral microemulsions. From the Foreword by Rainer H. Müller, PharmaSol GmbH Berlin, Germany, and Cornelia M. Keck, Phillips University of Marburg, Germany
1. Impact of Parenteral Microemulsion on Healthcare Therapeutics.
2.
Preformulation Studies for Microemulsion Formulation.
3. Role of Surfactant
and Co-Surfactants in Formulation of Microemulsions.
4. Application of
Quality by Design in Microemulsions.
5. Parenteral Self-Emulsifying Drug
Delivery.
6. Characterization of Parenteral Microemulsions.
7. Clinical
Aspects of Parenteral Microemulsion.
8. Pharmaceutical Applications of
Microemulsion for Parenteral Delivery.
9. Regulatory Perspective and Patents
for Parenteral Microemulsion Formulations.
10. Future Challenges for
Parenteral Microemulsion.
Vivek P. Chavda, MPharm, is an Assistant Professor of Pharmaceutics and Pharmaceutical Technology at the L. M. College of Pharmacy, Gujarat, India. Before joining academics, he worked in the biologics industry for almost eight years in research and development, with two successful regulatory filings at Lupin Biotech (Pune) and Dr. Reddys Laboratory (Hyderabad). He has published many national and international journal papers, book chapters, and newsletter articles and has nine patents in the pipeline. His research interests include the development of biologics processes and formulations, medical device development, nano-diagnostics, long-acting parenteral formulations, and nano-vaccines. He is serving as an editorial board member for various Scopus-indexed, peer-reviewed journals and was listed among the top 2% of scientists in the world by Stanford University and Elsevier in 2023 and 2024.
Vandana B. Patravale, PhD, is a Professor of Pharmaceutics at the Institute of Chemical Technology, Mumbai, India. Her research interests include development of nanocarriers with a major emphasis on infectious diseases, cancer and neurodegenerative disorders, medical device development, nanodiagnostics, and nano-vaccines. She has over 200 refereed publications, two books, and over 25 book chapters to her credit. She holds over 30 granted patents and has 14 patents in progress and two trademark registrations to her credit. She is the Vice President of the Controlled Release Society (Indian Chapter) and the National Convenor of the Womens Forum of the Association of Pharmaceutical Teachers of India. She has transferred more than 20 pharmaceutical technologies to various industries, including technology on drug-eluting stents, which are being marketed in more than 60 countries.
