Researchers in the chemical sciences and the plant sciences from the tropical regions of Africa and Asia provide an extensive three-volume reference on phytochemicals for students, researchers, and practitioners in a wide range of fields. The first volume covers fundamentals, modern techniques, and applications from such perspectives as phytochemicals as immunomodulators, plant metabolomics, analytical techniques in elemental profiling, computational phytochemistry in drug discovery: databases and tools, and phytochemical studies of five Nigerian indigenous vegetables. The second volume--on pharmcognosy, nanomedicine, and contemporary issues--discusses such topics as complementary and alternative systems of medicine, antimicrobial medicinal plants as effective natural bioresources, antioxidant potentials of cinnamon, the green biosynthesis of metallic nanoparticles, and toxic plants and phytochemical. The final volume is on marine sources, industrial applications, and recent developments. The topics there include marine antioxidants and assay methods, secondary metabolite accumulation and production through in vitro cultures, effective processing methods for fruits and vegetables, phytochemical biopesticides, and novel terpenoids as anti-cancer stem cell agents. Annotation ©2019 Ringgold, Inc., Portland, OR (protoview.com)
This first book in this three-volume set provides comprehensive coverage of a wide range of topics in phytochemistry. With chapters from professional specialists from key institutions around the world, the volume starts with an introduction to phytochemistry and details the fundamentals. Part II discusses the state-of-the-art modern methods and techniques in phytochemical research, while Part III provides an informative overview of computational phytochemistry and its applications. Part IV presents novel research findings in the discovery of drugs that will be effective in the treatment of diseases. The chapters are drawn carefully and integrated sequentially to aid flow, consistency, and continuity.
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xiii | |
| Abbreviations |
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xvii | |
| Foreword |
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xxi | |
| Preface |
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xxiii | |
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PART I Fundamentals of Phytochemistry |
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1 | (244) |
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1 Introduction to Phytochemistry |
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3 | (34) |
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Laurence John Francis J. Gido |
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2 Biosynthesis of Phytochemicals |
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37 | (42) |
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3 Mechanisms of Plant Defense Against Pathogens: Phytoalexins Induction |
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79 | (40) |
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4 Biological Roles of Phytochemicals |
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119 | (34) |
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Glioma Obianuju Peculiar-Onyekere |
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Christopher Obodike Ezugwu |
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5 Phytochemicals as Immunomodulators |
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153 | (26) |
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6 Phytochemicals as Nutraceuticals and Pharmafoods |
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179 | (18) |
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7 Role of Phytochemistry in Plant Classification: Phytochemotaxonomy |
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197 | (26) |
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Ifeoma Celestina Orabueze |
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223 | (22) |
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PART II Methods and Techniques |
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245 | (250) |
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9 Phytochemical Extraction, Isolation, and Detection Techniques |
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247 | (14) |
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Temitope Oluwabunmi Banjo |
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10 Techniques in Phytochemotaxonomy |
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261 | (26) |
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Ifeoma Celestina Orabueze |
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11 Chromatographical Techniques in Phytochemical Research |
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287 | (20) |
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12 Ultraviolet/Visible Spectroscopy and HPLC in Phytochemical Analysis: An Introduction |
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307 | (36) |
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13 High-Performance Liquid Chromatography and High-Performance Thin-Layer Chromatography as Sophisticated Tools in Phytochemical Analysis |
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343 | (24) |
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14 Analytical Techniques in Elemental Profiling |
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367 | (14) |
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15 Phytochemical Test Methods: Qualitative, Quantitative and Proximate Analysis |
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381 | (46) |
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16 Animal Models in Phytopharmacology |
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427 | (36) |
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Mulkah O. Ajagun-Ogunleye |
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17 Toxicological Testing of Plant Products |
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463 | (18) |
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18 Role of Biostatistics in Phytochemical Research: Emphasis on Essential Oil Studies |
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481 | (14) |
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PART III Computational Phytochemistry |
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495 | (74) |
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19 Computational Phytochemistry in Drug Discovery: Databases and Tools |
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497 | (16) |
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20 Sternness Modulation by Phytochemicals to Target Cancer Stem Cells |
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513 | (24) |
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21 Targeting Cancer Cell Carbohydrate Metabolism by Phytochemicals |
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537 | (24) |
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22 Herbal Drug Discovery: The Envision Biotechnology Approach |
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561 | (8) |
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PART IV Phytochemical Research |
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569 | (50) |
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23 Gas Chromatography-Mass Spectrometry Analysis and In Vitro Anticancer Activity of Tectona grandis Bark Extract Against Human Breast Cancer Cell Line (MCF-7) |
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571 | (16) |
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24 Phytochemical Analysis of Nigella sativa L. Seeds Aqueous Extract by Gas Chromatography-Mass Spectroscopy and Fourier-Transform Infrared |
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587 | (18) |
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Jagapriya I. Scnlhilkumar Balasubramanian |
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25 Phytochemical Studies on Five Nigerian Indigenous Vegetables |
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605 | (14) |
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| Index |
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619 | |
Chukwuebuka Egbuna is a chartered chemist, chemical analyst, and academic researcher. He is a member of the Institute of Chartered Chemists of Nigeria, the Nigerian Society of Biochemistry and Molecular Biology, and the Society of Quality Assurance (USA). He is a reviewer and editorial board member of various journals, with his most recent role as a website administrator for the Tropical Journal of Applied Natural Sciences.
Jonathan Chinenye Ifemeje, PhD, is a Senior Lecturer in the Department of Biochemistry, Faculty of Natural Sciences, Chukwuemeka Odumegwu Ojukwu University, Nigeria. He has published over 40 publications and is the Managing Editor of the Tropical Journal of Applied Natural Sciences. He is a member of various institutes, including the Institute of Chartered Chemists of Nigeria, the Nigerian Society of Biochemistry and Molecular Biology, and the Society of Quality Assurance.
Stanley Chidi Udedi, PhD, is a Full Professor of Biochemistry at the Department of Applied
Biochemistry, Nnamdi Azikiwe University, Nigeria, where he is also Dean of Students. He has taught at various institutions, including Madonna University, Nigeria, and Anambra State University, which is now Chukwuemeka Odumegwu Ojukwu University, Nigeria. He is well published with over 50 publications.
Shashank Kumar, PhD, is an Assistant Professor at the Center for Biochemistry and Microbial Sciences, Central University of Punjab, Bathinda, India. Dr. Kumar has about 60 published scientific papers, reviews, editorial articles, and book chapters in various national and international peer-reviewed journals and has been cited more than 1,200 times. He has also edited several books, including Concepts in Cell Signaling and Carbohydrate Metabolism: Theory and Practical Approach.
