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Practical Cardiology: Principles and Approaches 2nd edition [Pehme köide]

Edited by (Professor of Cardiology and Echocardiologist, Head of Cardio-Oncology Department & Research Center, Rajaie Cardiovascul), Edited by , Edited by (Professor of Cardiology, Shaheed Rajaei Cardiovascular, Medical & Research Center, Vali- Asr Avenue Tehran- Iran)
  • Formaat: Paperback / softback, 832 pages, kõrgus x laius: 235x191 mm, kaal: 1720 g
  • Ilmumisaeg: 19-Feb-2021
  • Kirjastus: Elsevier - Health Sciences Division
  • ISBN-10: 0323809154
  • ISBN-13: 9780323809153
Teised raamatud teemal:
  • Formaat: Paperback / softback, 832 pages, kõrgus x laius: 235x191 mm, kaal: 1720 g
  • Ilmumisaeg: 19-Feb-2021
  • Kirjastus: Elsevier - Health Sciences Division
  • ISBN-10: 0323809154
  • ISBN-13: 9780323809153
Teised raamatud teemal:
From basic clinical facts to new advanced guidelines, Practical Cardiology: Principles and Approaches covers all aspects of cardiology in one quick and current resource. Packed with useful tips and step-by-step guidance, this updated second edition reviews new drugs, new invasive and noninvasive therapeutic approaches, and new developments in cardiology foundations, imaging modalities, management approaches, and specific interventions for all common cardiovascular disease modalities in all patient care settings.

Offers practical plans of action for all major cardiovascular topics and diseases.



Includes three new chapters on electrophysiology (including tracing interpretation); mechanisms, diagnoses, and therapies; and hypotension, syncope, and sudden cardiac death.



Features updated and expanded content throughout, including new findings, non-ST elevation in specific populations (elderly, women), diabetes in heart disease, and more.



Provides integrated key points that offer quick clinical summaries for all aspects of common cardiovascular conditions.



Contains more than 125 full-color illustrations with many algorithms of diagnostic and therapeutic pathways.

Arvustused

"Overall the book is written in easy language with good examples of echo, pictures and diagrams as well as figures and easy to read for all capabilities." -Prakash P Punjabi, Editor-in-Chief, Perfusion

Contributors xix
Preface xxiii
Acknowledgments xxv
1 Evidence-Based Cardiology Practice
1(1)
Reza Yousefi-Nooraie
Pattiam Sadeghipour
Introduction
1(1)
Evidence-Based Medicine Resources
1(1)
Clinical Practice Guidelines
2(3)
Evidence Is Not Enough
5(1)
References
5(2)
2 Evaluation of Patient With Cardiovascular Problem
7(1)
Majid Maleki
History
7(2)
General Question
7(1)
Congestive Heart Failure Questions
7(1)
Ischemic Heart Disease (Questions)
7(1)
Congenital Heart Disease (Questions)
8(1)
Rheumatic Heart Disease and Endocarditis (Questions)
8(1)
Dyspnea (Questions)
8(1)
Syncope (Questions)
8(1)
Chest Pain (Questions)
8(1)
Physical Examination
9(7)
Patient Observation
9(1)
Arterial Pulse Examination
9(1)
Venous Pulse Examination
9(1)
Normal Jugular Venous Pulse (JVP)
9(1)
Palpation and Observation of the Chest
9(3)
Auscultation
12(2)
Auscultation of the Heart
14(2)
Differential Diagnosis of Murmurs by Maneuvers
16(1)
Further Reading
16(1)
3 Electrocardiography
17(45)
Mohammad Javad Alemzadeh-Ansari
Introduction
17(1)
Normal Electrocardiograms
17(6)
The Pattern of Normal Waves and Intervals
17(2)
Normal Variants on Electrocardiograms
19(2)
Benign Early Repolarization
21(2)
Abnormal Electrocardiograms
23(35)
Malignant Early Repolarization
23(1)
Atrial Abnormality
23(1)
Ventricular Hypertrophy
23(6)
Intraventricular Conduction Delays
29(7)
Alternans Patterns on Electrocardiograms
36(3)
Technical Errors and Artifacts
39(19)
References
58(4)
4 Exercise Stress Testing
62(5)
Sedigheh Saedi
Indications for EST
62(1)
Contraindications
62(1)
Absolute
61(1)
Relative Contraindications
61(1)
Exercise Stress Test Protocols
62(1)
Evaluation of Functional Capacity
62(1)
Heart Rate Response
62(1)
Blood Pressure Response
63(1)
Hypertensive Response
63(1)
Hypotensive Response
63(1)
Electrocardiogram Changes
63(2)
Normal Response
63(1)
Rapid Upsloping Response
63(1)
Slow Upsloping ST Changes
64(1)
Horizontal ST-Segment Depression
64(1)
Minor ST-Segment Changes
64(1)
Downsloping ST-Segment Depression
64(1)
ST-Segment Elevation
64(1)
ST-Segment Elevation in Leads With Previous Q Wave
65(1)
Arrhythmias
65(1)
Recovery
66(1)
Indications for Termination of Exercise Stress Testing
66(1)
References
66(1)
5 Echocardiography
67(44)
Anita Sadeghpour
Azin Alizadehasl
Transthoracic Study
67(6)
Standard Windows
67(6)
Doppler Echocardiography
73(5)
Doppler Study in Standard Views
76(2)
Myocardial Tissue Doppler Imaging
78(1)
Transesophageal Echocardiography
79(1)
Contrast Echocardiography
80(1)
Stress Echocardiography
80(1)
Study of Myocardial Viability
81(1)
Three-Dimensional Echocardiography
81(1)
Two-Dimensional (Speckled) Strain Echocardiography
81(1)
Study of the Cardiac Chambers
82(3)
Left Ventricular Volume
82(1)
Left Ventricular Systolic Function
82(2)
Left Ventricular Diastolic Function
84(1)
Left Atrium
84(1)
Right Ventricle
85(1)
Right Atrium
85(1)
Study of Valvular Heart Disease
85(23)
Mitral Valve Disease
85(5)
Aortic Valve Disease
90(2)
Tricuspid Valve Disease
92(1)
Pulmonary Valve Disease
92(1)
Prosthetic Heart Valves
92(3)
Infective Endocarditis
95(2)
Ischemic Heart Disease
97(1)
Regional Wall Motion Abnormalities
97(1)
Acute Complications of Myocardial Infarction
97(1)
Cardiomyopathies: Dilated Cardiomyopathy
98(1)
Hypertrophic Cardiomyopathy
98(1)
Restrictive Cardiomyopathy
98(1)
Endomyocardial Fibrosis
98(1)
Noncompaction Cardiomyopathy
98(1)
Arrhythmogenic Right Ventricular Dysplasia
99(1)
Pericardial Disease
99(1)
Pericardial Effusion and Tamponade
99(1)
Pericardial Constriction
100(1)
Pericardial Cysts
101(1)
Intracardiac Masses and Tumors
101(1)
Intracardiac Thrombi
101(1)
Aortic Disease
102(1)
Proximal Aorta Disease
102(1)
Congenital Heart Disease
102(1)
Atrial Septal Defects
102(2)
Ventricular Septal Defects
104(1)
Patent Ductus Arteriosus
105(1)
Tetralogy of Fallot
106(1)
Transposition of the Great Arteries
106(1)
Truncus Arteriosus
106(1)
Double-Outlet Right Ventricle
107(1)
Cardiac Resynchronization Therapy
107(1)
Ventricular Assist Devices
107(1)
Cardiac Interventional Procedures
108(1)
References
108(3)
6 Chest Radiography in Cardiovascular Disease
111(1)
Hamldreza Pouraliakbar
Normal Chest Radiographs
111(1)
Lungs and Pulmonary Vasculature
112(1)
The Chest Radiograph in Heart Disease
112(1)
Overview
112(1)
Thoracic Musculoskeletal Structures
112(1)
Pulmonary Vascularity
113(1)
Determining the Vascular Pattern
113(1)
Eisenmenger Syndrome
114(1)
Pulmonary Venous Hypertension
114(1)
Cardiac Chambers and Great Vessels
115(1)
Specific Chamber Enlargement
115(3)
Mitral Valve Disease
118(2)
Mitral Valve Stenosis
118(2)
Mitral Regurgitation
120(1)
Aortic Valve Disease
120(1)
Aortic Stenosis
120(1)
Aortic Regurgitation
120(1)
Radiography
120(1)
Pulmonary Stenosis
121(1)
Valvular Pulmonary Stenosis
121(1)
Radiography
122(1)
Pulmonary Regurgitation
122(1)
Radiography
122(1)
Tricuspid Valve Disease
123(1)
Tricuspid Stenosis
123(1)
Tricuspid Valve Regurgitation
123(1)
Radiography
123(1)
Congenital Heart Disease
123(6)
Radiography of Congenital Heart Disease
123(1)
Clinical-Radiographic Classification of Congenital Heart Disease
123(5)
Coarctation of the Aorta
128(1)
References
129(2)
7 Cardiac Computed Tomography
131(44)
Hamidreza Pouraliakbar
MDCT Terminology
131(1)
Isotropic Data Acquisition
131(1)
Spatial/Temporal Resolution
131(1)
Scan Modes
132(3)
New Technologies
132(3)
Radiation Exposure
135(1)
Patient Preparation
135(1)
Image Acquisition
136(1)
Cardiac Computed Tomography Anatomy
136(3)
Cardiac Chambers
136(1)
Image Reconstruction
136(3)
Calcium Scoring
139(6)
Prognostic Implications of CACS
140(5)
Coronary Computed Tomographic Angiography
145(618)
Diagnostic Accuracy
145(1)
Prognostic Implications
145(2)
Imaging of Coronary Stents
147(2)
Coronary CT Angiography in Patient With Prior CABG
149(1)
Atherosclerotic Plaques
149(1)
High-Risk Plaque Features
149(2)
Relationship of Findings to Ischemia
151(6)
Use in Patients With Acute Chest Pain
157(2)
Use in Patients With Stable Suspected Coronary Artery Disease
159(3)
Anomalous Coronary Arteries
162(1)
Assessment of Cardiovascular Structure and Function
163(1)
Valvular Heart Disease
164(1)
Structural Heart Disease Interventions
165(4)
References
169(5)
Further Reading
174(1)
8 Cardiac Magnetic Resonance Imaging
175(10)
Hamid Mojibian
Hamldreza Pouraliakbar
Basic Physics, Technical Considerations, and Imaging Tools
175(2)
Hardware and Technical Requirements
177(1)
Clinical Applications
178(3)
Anatomic Visualization
178(1)
Functional Evaluation
178(2)
Tissue Characterization
180(1)
Patient Selection and Preparation
181(1)
Specific Indications and Magnetic Resonance Techniques
182(1)
Tissue Characterization and Parametric Mapping
183(1)
References
183(2)
9 Nuclear Cardiology
185(8)
Hadi Malek
Introduction
185(1)
Radiopharmaceuticals
185(1)
Detection of Coronary Artery Disease and Stress Tests
185(1)
Electrocardiography-Gated SPECT
186(1)
Image Interpretation
186(1)
Semiquantitative Visual Analysis
186(1)
Normal Variations, Artifacts, and Pitfalls
186(4)
Assessment of Viability
190(1)
Radionuclide Angiography
190(1)
Positron Emission Tomography
190(1)
Radionuclide Imaging of Cardiac Amyloidosis
190(1)
References
190(3)
10 Catheterization and Angiography
193(8)
Ali Zahed Mehr
Introduction
193(1)
Radiation Safety
193(1)
Precatheterization Preparations
193(1)
Access
194(1)
Radial Access
195(1)
Sheaths and Catheters
195(1)
Coronary Angiography Catheters
195(1)
Guidewires
196(1)
Left Heart Catheterization
196(1)
Right Heart Catheterization
196(1)
Coronary Angiography Indications
196(1)
Coronary Catheter Manipulation
197(1)
Left Judkins Catheter
197(1)
Right Judkins Catheter
197(1)
Coronary Anatomy
197(1)
Angiographic Projections
198(1)
Coronary Findings and Interpretation
198(1)
Calcification
198(1)
Thrombus
198(1)
Stenosis
198(1)
Lesion Complexity for Intervention
198(1)
Ectasia
198(1)
Coronary Spasm
199(1)
Coronary Anomalies and Variations
199(1)
Absent Left Main Artery
199(1)
Anomalous Origin of the Left Circumflex Artery From the Right Coronary Artery
199(1)
Anomalous Origin of the Left Main or Left Anterior Descending Coronary Artery From the Right Coronary Artery
199(1)
Anomalous Origin of the Right Coronary Artery From the Left Cusp
199(1)
Coronary Fistula
199(1)
Muscle Bridge
199(1)
Catheterization Complications
199(1)
Pseudoaneurysm
200(1)
Arteriovenous Fistula
200(1)
Retroperitoneal Hematoma
200(1)
References
200(1)
11 Hemodynamic Study
201(16)
Nasim Naderi
Introduction
201(6)
Pressure Measurement
207(1)
Oximetry Measurements
207(1)
Temperature Measurements
207(1)
Cardiac Performance
207(1)
Cardiac Index
202(1)
Thermodilution Cardiac Output
202(1)
Limitations of the Thermodilution Technique
202(1)
Fick Cardiac Output
203(1)
Oxygen Consumption
203(1)
Cardiac Output by Left Ventriculography
203(1)
Filling Pressures (Preload)
203(1)
Right and left heart Catheterization
203(1)
Pulmonary Artery Catheter and Swan-Ganz Catheter
204(1)
Central Venous Pressure Measurement and Interpretation
204(1)
Central Venous Pressure Waveforms
204(2)
Abnormal Central Venous Pressure Waveforms
206(1)
Left Heart Filling Pressures
206(1)
Ventricular Pressure
206(1)
Vascular Resistances
206(1)
Clinical Implications of Right Heart Catheterization
207(7)
Heart Failure Hemodynamics
207(1)
Pulmonary Hypertension Hemodynamics
207(2)
The Hemodynamics of Valvular Heart Disease
209(1)
Assessment of Valvular Stenosis
209(1)
Practical Points In Hemodynamic Study of Valvular Regurgitation
210(1)
The Hemodynamics of Pericardial Disease
210(1)
Cardiac Tamponade
210(4)
Intra-aortic Balloon Pump
214(2)
References
216(1)
12 Heart Failure and Pulmonary Hypertension
217(40)
Nasim Naderi
Heart Failure Definition
217(1)
Key Points
217(1)
Diagnostic Workup for Heart Failure
217(2)
Key Points About Natriuretic Peptides
217(2)
Electrocardiography
219(1)
Echocardiography
219(1)
Other Diagnostic Tests
219(1)
Acute Heart Failure
219(13)
Acute Heart Failure in the Emergency Department
219(2)
Diagnosis and Prognosis
221(1)
Diagnostic Investigations
221(2)
Management ofAHF
223(6)
Indications for Invasive and Swan-Ganz Monitoring
229(1)
Some Practical Recommendations About Patients With Acute Heart Failure
230(1)
Discharge Plan
230(2)
Therapeutic Approach to Chronic Heart Failure
232(13)
Therapeutic Approach to Patients With Heart Failure and Reduced Ejection Fraction
232(9)
Indications for Heart Transplantation and Mechanical Circulatory Support
241(1)
Management of Right Ventricular Failure
242(3)
Pulmonary Hypertension
245(8)
References
253(4)
13 Tachyarrhythmias
257(22)
Majid Haghjoo
Introduction
257(1)
Clinical Presentation
257(19)
Narrow Complex Tachycardia
258(11)
Wide Complex Tachycardia
269(7)
References
276(3)
14 Cardiac Implantable Electronic Devices
279(10)
Majid Haghjoo
Introduction
279(1)
NBG Codes for Pacemakers
279(1)
NBD Codes for Defibrillators
280(7)
Classification of Cardiac Implantable Electronic Devices
287(1)
Transvenous Systems
281(1)
Epicardial Systems
281(1)
Novel Systems
281(1)
Components of Cardiac Implantable Electronic Devices
281(1)
Pulse Generator
281(1)
Pacing or High-Voltage Leads (Electrodes)
281(1)
Pacing Modes
282(1)
VOO/AOO Mode
282(1)
WI/AAI Mode
282(1)
WIR/AAIR
282(1)
Hysteresis
282(1)
Noise Reversion
282(1)
VDD Mode
282(1)
DOO Mode
282(1)
DDI/DDIR Mode
282(1)
DDD/DDDR Mode
282(1)
Timing Cycle of Pacing
282(2)
Single-Chamber Timing
283(1)
Dual-Chamber Timing
283(1)
Upper Rate Behavior
284(1)
Programming Considerations for Implantable Cardioverter Defibrillators
284(1)
Minimizing Right Ventricular Pacing
284(1)
Shock Reduction
285(1)
Optimizing Cardiac Resynchronization Therapy by Device Programming
285(1)
Troubleshooting
285(3)
Undersensing
285(1)
Oversensing
286(1)
Loss of Capture
286(1)
No Output
287(1)
Pseudomalfunctions
287(1)
References
288(1)
15 Bradyarrhythmias
289(8)
Majid Haghjoo
Introduction
289(1)
Clinical Presentation
289(1)
Sinus Node Dysfunction
289(3)
Etiology
289(1)
Classification
290(1)
Diagnostic Modalities
290(2)
Atrioventricular Block
292(3)
Etiology
292(1)
Classification
292(2)
Diagnostic Modalities
294(1)
Treatment
294(1)
References
295(2)
16 Electrophysiology Tracing Interpretation
297(82)
Amir Farjam Fazelifar
Introduction
297(1)
What Is Electrophysiology (EP) Procedure?
297(1)
EP Catheter Implantation
297(1)
Electrophysiology Tracing Structure
298(1)
Signal Recording and Sequences in Normal Heart
298(2)
Pacing Maneuvers in an Electrophysiology Study
300(1)
Overdrive Pacing Effect on Conduction System
300(3)
Atrium
300(1)
AVN and His Bundle
300(3)
Ventricle
303(1)
Programmed Electrical Stimulation maneuver
303(4)
Atrium
303(1)
AVN and His Bundle
304(3)
Ventricle
307(1)
Role of EPS in Bradyarrhythmia detection
307(5)
How to Interpret Tachyarrhythmia Tracing?
312(3)
Usual Arrhythmia Characteristics
315(2)
Atrial Tachycardia
315(1)
AVN Reentrant Tachycardia
315(1)
Junctional Tachycardia
315(1)
Orthodromic AVRT
315(1)
Antidromic AVRT
315(1)
Ventricular Tachycardia
315(2)
References
317(2)
17 Mechanisms, Diagnosis, and Therapy of Cardiac Arrhythmia
319(1)
Shabnam Madadi
Introduction
319(1)
Mechanisms of Cardiac Arrhythmias
319(2)
History and Physical Exam
321(1)
Antiarrhythmic Drugs
321(4)
Nonpharmacological Treatment of Cardiac Arrhythmia
325(1)
References
325(4)
18 Hypotension and Syncope
329(1)
Farzad Kamali
Definition
329(1)
Prevalence
329(1)
Classification of Syncope
329(1)
Diagnosis
329(4)
1 Clinical Presentation and Treatment of Common Causes of Syncope
333(4)
Driving Restrictions
337(1)
References
338(3)
19 Preventive Cardiology
341(36)
Majid Maleki
Zahra Hosseini
Assessment of Cardiovascular Risk
341(1)
Hypertension
341(4)
Dyslipidemia
345(10)
ESC/EAS 2019 Guideline
346(3)
AHA 2019 Preventive Guideline
349(6)
Smoking
355(1)
Diabetes and Metabolic Syndrome
356(8)
Prevention of CVD in Diabetic Patients
358(1)
Glycemic, Blood Pressure, and Lipid Targets in Patients With Diabetic Mellitus
359(5)
Metabolic Syndrome (Syndrome X)
364(1)
Obesity
364(1)
Diet and Supplements
365(1)
Alcohol Consumption
365(1)
Vitamin D
365(1)
Coenzyme Q10
366(1)
Inflammatory Markers
366(1)
Cardiac Rehabilitation
366(1)
References
367(10)
20 Hypertension
377(10)
Ali Zahed Mehr
Introduction
377(1)
Mechanisms of Hypertension
377(1)
Diagnosis of Hypertension
378(1)
Initial Evaluation
379(1)
Secondary Hypertension
379(1)
Hypertension Management
379(4)
Lifestyle Modification
379(1)
Drug Therapy
380(3)
Resistant Hypertension
383(1)
Hypertension in Pregnancy
383(1)
Perioperative Hypertension Management
384(1)
Therapeutic Goals in Hypertension
384(1)
Acute Blood Pressure Elevations
384(1)
References
385(2)
21 Dyslipidemia
387(8)
Reza Kiani
Introduction
387(1)
Biochemistry and Metabolism of Lipids
387(2)
Intestinal Pathway
388(1)
Hepatic Pathway
388(1)
Reverse Cholesterol Transport
389(1)
Lipoprotein Disorders
389(1)
Primary Lipid Disorders
389(1)
Impact of Lipoprotein Disorders on Cardiovascular Risk
390(1)
Management of Lipoprotein Disorders
390(2)
Statins
390(1)
Ezetimibe
391(1)
Fibrates
391(1)
Niacin
391(1)
Bile Acid Sequestrants
391(1)
Fish Oil
391(1)
Plant Sterols/Stanols
391(1)
Mipomersen
392(1)
Lomitapide
392(1)
PCSK9 Inhibitors
392(1)
LDL Apheresis
392(1)
Treatment Goals in Lipoprotein Disorders
392(1)
References
392(3)
22 ST-Segment Elevation Myocardial Infarction
395(18)
Bahram Mohebbi
Definition
395(1)
ST-Segment Elevation Myocardial Infarction in Special Groups
396(1)
Clinical Evaluation
396(11)
Electrocardiography
397(1)
Cardiac Biomarkers
397(1)
Treatment
398(1)
Coronary Artery Bypass Graft Surgery
398(1)
Medications
399(1)
Fibrinolysis for Acute ST-Segment Elevation Myocardial Infarction
400(1)
Complications of ST-Segment Elevation Myocardial Infarction
401(1)
Conduction Abnormalities After Myocardial Infarction
401(1)
Mechanical Complications of ST-Segment Elevation Myocardial Infarction
402(2)
Pericardial Complications of Myocardial Infarction
404(1)
References
405(8)
23 Non-ST-Elevation Acute Coronary Syndromes
413(1)
Samad Ghaffari
Introduction
413(1)
Pathophysiology
414(1)
Initial Assessment
414(2)
History
414(1)
Physical Examination
414(1)
Electrocardiography
415(1)
Cardiac Biomarkers
415(1)
Noninvasive Testing
416(1)
Invasive Coronary Angiography
416(1)
Risk Stratification
416(1)
Management
417(1)
Anti-ischemic Drugs
418(1)
Nitrates
418(1)
Beta-Blockers
418(1)
Calcium Channel Blockers
418(1)
Analgesics
419(1)
Antiplatelet Therapy
419(2)
Aspirin
419(1)
Oral P2Y12 Inhibitors
419(1)
Clopidogrel
419(1)
Prasugrel
419(1)
Ticagrelor
420(1)
Intravenous Antiplatelet Agents
420(1)
Anticoagulant Therapy
421(2)
Unfractionated Heparin
421(1)
Low-Molecular-Weight Heparin
422(1)
Bivalirudin
422(1)
Fondaparinux
422(1)
Lipid-Lowering Agents
423(1)
Early Invasive vs Conservative Strategies
423(1)
Long-Term Management
424(1)
Management of NSTE-ACS in Special Subgroups
424(1)
Elderly
424(1)
Chronic Kidney Disease
424(1)
Diabetes
425(1)
Prinzmetal Variant Angina
425(1)
References
425(4)
24 Stable Ischemic Heart Disease
429(26)
Majid Kyavar
Mohammad Javad Alemzadeh-Ansari
Introduction
429(1)
Pathophysiology
429(1)
Clinical Manifestations
430(2)
Physical Examination
432(1)
Differential Diagnosis
433(1)
Diagnosis
433(5)
Resting Electrocardiogram
433(1)
Biochemical Tests
434(1)
Echocardiography at Rest
434(1)
Chest X-Ray
435(1)
Probability Estimate of CAD
435(1)
Noninvasive Stress Testing
436(1)
Invasive Testing
437(1)
Treatment
438(8)
Medical Management
440(1)
Nonpharmacologic Treatment of Refractory Angina
440(1)
Coronary Artery Disease Revascularization
440(2)
Revascularization (Coronary Artery Bypass Grafting or Percutaneous Coronary Intervention) vs Medical Therapy
442(1)
Coronary Artery Bypass Grafting vs Percutaneous Coronary Intervention
443(3)
Special Groups
446(2)
Women
446(1)
Older Patients
447(1)
Diabetes Mellitus
447(1)
Renal Insufficiency
447(1)
After Heart Transplantation
447(1)
Cancer
447(1)
Follow-up of Patients With Stable Ischemic Heart Disease
448(1)
References
448(5)
Further Reading
453(2)
25 Percutaneous Coronary Intervention
455(8)
Ata Firouzi
Plain Old Balloon Angioplasty
455(1)
Bare Metal Stents
455(1)
Drug-Eluting Stents
455(1)
Stent Thrombosis
455(1)
Chronic Stable Angina
456(1)
Percutaneous Coronary Intervention in Left Main Coronary Artery Lesions
456(1)
Multivessel Disease
457(1)
Patients With Diabetes Mellitus
457(1)
Percutaneous Coronary Intervention in Acute Coronary Syndrome
457(1)
Intravascular Ultrasonography
457(1)
Fractional Flow Reserve
458(1)
Rotablator (Rotational Atherectomy)
459(1)
Postintervention Care
460(1)
References
460(3)
26 Transcatheter Therapies for Structural Heart Diseases
463(12)
Hamidreza Sanati
Intervention in Structural Heart Disorders
463(1)
Occlusion of Cardiac Defects
463(4)
Patent Foramen Ovale
463(1)
Atrial Septal Defect
464(1)
Ventricular Septal Defect
465(1)
Left Atrial Appendage Occlusion
465(1)
Paravalvular Leak Closure
466(1)
Mitral Valve Interventions
467(1)
Balloon Mitral Valvuloplasty
467(1)
Percutaneous Mitral and Tricuspid Valve Repair and Replacement
468(1)
Aorta and Aortic Valve Interventions
468(2)
Balloon Aortic Valvuloplasty
468(1)
Transcatheter Aortic Valve Implantation
468(2)
Coarctation of the Aorta
470(1)
Pulmonary Valve Intervention
470(2)
Pulmonary Valvuloplasty
470(2)
Percutaneous Pulmonary Valve Implantation
472(1)
References
472(3)
27 Aortic Disorders and Their Management
475(20)
Omid Shafe
Aortic Diseases
475(1)
Epidemiology and Screening Strategies of Aortic Aneurysms
475(1)
Abdominal Aortic Aneurysms
475(1)
Thoracic Aortic Aneurysms
476(1)
Pathology and Pathophysiology of Aortic Aneurysms
476(4)
Abdominal Aortic Aneurysm
476(2)
Thoracic Aortic Aneurysm
478(2)
Management
480(1)
Medical Therapy
480(1)
Open Surgery or Endovascular Therapy
480(1)
Acute Aortic Syndromes
480(12)
Aortic Dissection and Its Variants
480(6)
Approach to Patients With Suspicious Aortic Dissection
486(4)
Aortic Dissection Variants
490(2)
References
492(3)
28 Peripheral Artery Disease
495(10)
Jamal Moosavi
Epidemiology
495(1)
Clinical Manifestations
495(1)
Diagnosis
496(4)
Imaging
497(1)
Disease Severity Classification
498(1)
Screening
498(2)
Treatment
500(2)
Antiplatelet and Anticoagulant Therapy
500(1)
Statins
500(1)
Glycemic Control
500(1)
Smoking Cessation
500(1)
Antihypertensive Therapy
501(1)
Supervised Exercise Training
501(1)
Specific Drugs for Treatment of Claudication
501(1)
Endovascular or Surgical Intervention
502(1)
References
502(3)
29 Cardiomyopathies and Myocarditis
505(22)
Nasim Naderi
Background
505(1)
Dilated Cardiomyopathy
505(3)
Key Points About Peripartum Cardiomyopathy
505(3)
Arrhythmogenic Right Ventricular Cardiomyopathy
508(1)
Restrictive Cardiomyopathy
508(6)
Background
508(1)
Key Points About Restrictive Cardiomyopathy
508(1)
Idiopathic Primary Restrictive Cardiomyopathy
508(1)
Infiltrative Restrictive Cardiomyopathy
508(1)
Key Points About Eosinophilic Cardiomyopathy (Loeffler Endocarditis) and Endomyocardial Fibrosis
508(1)
Amyloidosis
509(1)
Hemochromatosis
509(3)
Cardiac Sarcoidosis
512(1)
Constrictive vs Restrictive Physiology
513(1)
Hypertrophic Cardiomyopathy
514(9)
Background
514(1)
Key Points About Hypertrophic Cardiomyopathy
514(1)
Diagnostic Criteria
514(1)
Key Points About Hypertrophic Cardiomyopathy
515(1)
Treatment of Obstructive Hypertrophic Cardiomyopathy
515(1)
Hemodynamic Study of Hypertrophic Cardiomyopathy
516(1)
Myocarditis
517(6)
References
523(4)
30 Valvular Heart Disease
527(46)
Feridoun Noohi
Anita Sadeghpour
Azin Alizadehasl
Aortic Valve
527(10)
Aortic Stenosis
527(6)
Bicuspid Aortic Valve
533(3)
Aortic Regurgitation
536(1)
Myocardial Ischemia
537(6)
Chronic Aortic Insufficiency
537(1)
Acute Aortic Insufficiency
537(4)
Acute Aortic Regurgitation
541(2)
Mitral Valve Disease
543(5)
Mitral Stenosis
543(5)
Mitral Regurgitation
548(5)
Etiology and Pathology
548(3)
Acute Mitral Regurgitation
551(2)
Mitral Valve Prolapse
553(2)
Management
554(1)
Tricuspid Valve Disease
555(4)
Normal Anatomy
555(1)
Pathology
555(1)
Clinical Findings
555(1)
Physical Examination
555(1)
Medical and Surgical Treatment of Severe Tricuspid Regurgitation
556(1)
Tricuspid Stenosis
556(3)
Pulmonary Valve Stenosis
559(1)
Clinical Findings
559(1)
Diagnostic Testing
559(1)
Management and Follow-up
560(1)
Pulmonic Regurgitation
560(7)
Pathology
560(1)
Clinical Presentation
560(1)
Physical Examination
560(1)
Auscultation
560(1)
Diagnostic Testing
560(1)
Treatment
561(1)
Prosthetic Heart Valves
561(1)
Mechanical Valves
561(1)
Measurable Parameters
562(5)
Percutaneous Valve Replacement
567(1)
Conclusions
567(1)
References
567(6)
31 Infective Endocarditis
573(18)
Azin Alizadehasl
Anita Sadeghpour
Epidemiology
573(1)
Microbiology
573(3)
Blood Culture-Positive Infective Endocarditis
573(1)
Blood Culture-Negative Infective Endocarditis
574(1)
Histologic Features of Infective Endocarditis
574(2)
Diagnosis
576(6)
Clinical Presentation
576(2)
Laboratory Findings
578(1)
Imaging Techniques
578(2)
Diagnostic Criteria
580(2)
Treatment
582(6)
Antimicrobial Therapy
582(4)
Indications and Timing of Surgery
586(1)
Outpatient Management and Follow-Up Evaluation
586(2)
Short-Term Follow-Up
588(1)
Long-Term Prognosis
588(1)
References
588(3)
32 Pericardial Disease
591(1)
Anita Sadeghpour
Azin Alizadehasl
Normal Pericardium, Anatomy, and Function
591(1)
Causes, Epidemiology, and Pathophysiology of Acute Pericarditis
591(1)
Epidemiology
591(2)
Clinical Presentation, History, and Physical Examination
593(1)
Diagnosis
593(1)
Natural History and Management
594(1)
Relapsing and Recurrent Pericarditis
595(1)
Pericardial Effusion
595(1)
Tamponade
596(3)
Pathophysiology and Hemodynamics
596(1)
Specific Types of Tamponade
596(1)
Clinical Features
596(1)
Diagnostic Testing
597(1)
Management
598(1)
Constrictive Pericarditis
599(4)
Pathophysiology
599(1)
Clinical Findings
599(1)
Physical Examination
599(1)
Diagnostic Findings
599(2)
Differentiating Constrictive Pericarditis From Restrictive Cardiomyopathy
601(1)
Differentiating Constrictive Pericarditis From COPD
601(1)
Management
601(2)
Effusive-Constrictive Pericarditis
603(1)
Specific Causes of Pericardial Disease
603(2)
Infectious Disease
603(1)
Pericardial Disease in Human Immunodeficiency Virus: Causes and Pathology
603(1)
Tuberculosis
603(1)
Pericarditis in Patients With Renal Disease
604(1)
Dressier Syndrome and Postmyocardial Infarction Pericarditis
604(1)
Pericardial Disease in Cancer
604(1)
Postcardiac Surgery Pericarditis
605(1)
Pericardial Effusion in Infective Endocarditis
605(1)
Stress Cardiomyopathy
605(1)
Hemopericardium
605(1)
Conclusion
605(1)
References
605(1)
Further Reading
606(1)
33 Congenital Heart Disease
607(28)
Zahra Khajali
Sedigheh Saedi
Basic Nomenclature and Segmental Approach to Congenital Heart Disease
607(2)
Sidedness (Situs)
607(1)
Cardiac Orientation
607(1)
Atrioventricular Connections
607(1)
Ventriculoarterial Connections
607(2)
Clinical Issues in Congenital Heart Disease
609(1)
Cyanosis
609(1)
Pulmonary Arterial Hypertension and Eisenmenger Syndrome
609(61)
Heart Failure
670(2)
Clinical Evaluation of Congenital Heart Disease
610(1)
Electrocardiography
610(1)
Echocardiography, Magnetic Resonance Imaging, and Computed Tomography
610(1)
Cardiac Catheterization and Hemodynamic Study
610(12)
Specific Congenital Cardiac Defects
612(1)
Shunt Defects
612(5)
Cyanotic Heart Defects
617(10)
Outflow Tract Lesions
627(2)
Valvular Pulmonary Stenosis
629(1)
Other Valvular and Miscellaneous Lesions
629(2)
Fontan Operation
631(2)
References
633(2)
34 Venous Thromboembolism
635(30)
Farshad Shakerian
Parham Sadeghipour
Azita Haj Hossein Talasaz
Introduction
635(1)
Epidemiology
635(1)
Clinical Risk Factors
635(2)
Pathophysiology of VTE
637(2)
Approach to Patients With Acute DVT
639(6)
History and Physical Examination
639(1)
Differential Diagnosis
640(1)
Diagnostic Modalities
641(1)
Practical Approach for Patients With Suspected DVT
642(1)
Approach to Patients With Acute PE
642(1)
Diagnostic Modalities
642(3)
Additional Test for Patients With Established VTE
645(1)
Screening for Hypercoagulable State
645(1)
Screening for Malignancies
646(1)
Clinical Course
646(2)
Recurrent VTE
646(2)
Postthrombotic Syndrome
648(1)
Chronic Thromboembolic Pulmonary Hypertension
648(1)
Post-PE Syndrome
648(1)
Treatment
648(9)
Anticoagulation
648(7)
Systemic Thrombolytic Therapy in Patients With VTE
655(1)
Pharmacomechanical Catheter-Directed Therapies
656(1)
Surgical Management
657(1)
Special Therapeutic Consideration for Patients With VTE
657(1)
Ambulation in Patients With DVT
657(1)
Inferior Vena Cava Filters
657(1)
Outpatient Management
657(1)
Multidisciplinary Pulmonary Embolism Response Team
657(1)
Prevention
657(2)
Inhospital Risk Factors for VTE and Bleeding
658(1)
Inhospital Prophylaxis
658(1)
Mechanical Prophylaxis
658(1)
Prophylaxis in Major Orthopedic Surgery
659(1)
References
659(6)
35 Genetics of Cardiovascular Disease and Applications of Genetic Testing
665(10)
Nejat Mahdieh
Bahareh Rabbani
Majid Maleki
Introduction
665(4)
Genetic Testing and Variant Interpretation
669(1)
Molecular Genetic Tests
669(1)
Monogenic Forms of Congenital Heart Defects
670(1)
Inherited Cardiomyopathies
670(7)
Dilated cardiomyopathy
670(1)
Hypertrophic Cardiomyopathy
670(1)
Restrictive Cardiomyopathy
670(7)
Left Ventricular Noncompaction Cardiomyopathy
677(1)
Arrhythmogenic Ventricular Cardiomyopathy
671(6)
Cardiac Electrophysiology
671(1)
Long QT Syndrome
671(1)
Short QT Syndrome
672(1)
Catecholaminergic Polymorphic Ventricular Tachycardia
672(1)
Brugada Syndrome
672(1)
Pharmacogenomics and Polymorphisms
672(1)
Warfarin Dosing and Clopidogrel Resistance
672(1)
Coagulation and Fibrinolysis
672(1)
Future Perspectives
672(1)
References
673(2)
36 Renal Disorders and Cardiovascular Disease
675(10)
Samira Tabiban
Nasim Naderi
Homeostasis
675(1)
General Considerations
675(1)
Classifications and Definitions
675(1)
Diagnosis
676(1)
Respiratory Acidosis
677(1)
Respiratory Alkalosis
677(1)
Metabolic Acidosis
678(1)
Metabolic Alkalosis
679(1)
Cardiorenal Syndrome
680(4)
Practical Points in Cardiorenal Syndrome Type 1
680(1)
Clinical Scenarios for Cardiorenal Syndrome Type 1
681(1)
Practical Points in Cardiorenal Syndrome Type 2
681(1)
Cardiorenal Syndrome Type 3: Acute Renocardiac Syndrome
682(1)
Cardiorenal Syndrome Type 4: Chronic Renocardiac Syndrome
682(1)
Cardiorenal Syndrome Type 5 (Secondary CRS)
682(2)
References
684(1)
37 Endocrine Disorders and the Cardiovascular System
685(8)
Zahra Ghaemmaghami
Growth Hormone
685(1)
Adult GH Deficiency
685(1)
GH Deficiency and Cardiovascular Risk Factor
686(1)
Acromegaly
686(1)
Cardiovascular System and Acromegaly
686(1)
Thyroid and Cardiovascular System
686(1)
Thyrotoxicosis
686(1)
Clinical and Hemodynamic Manifestation
686(1)
Hypothyroidism
687(1)
Thyroid and Amiodarone
687(1)
Treatment
687(1)
Amiodarone-lnduced Thyrotoxicosis
687(1)
Endocrine Hypertension
688(1)
Cushing Syndrome
688(1)
Vitamin D and Cardiovascular System
689(1)
References
689(4)
38 The Heart and Pulmonary Diseases
693(14)
Hasan Allah Sadeghi
Introduction
693(1)
Heart Dysfunction Caused by Chronic Respiratory Disease
693(3)
Interstitial Lung Diseases or Diffuse Parenchymal Lung Diseases
694(1)
Sleep Apnea and Hypoventilation Syndrome
694(2)
Pathophysiology
696(1)
Clinical Presentation and Diagnosis
696(1)
Treatment
697(1)
Systemic Diseases With Concomitant Lung and Heart Involvement
698(1)
Malignant Lung Diseases and the Heart
698(1)
References
699(8)
39 Cardiovascular Drugs and Hemostasis
707(30)
Bahram Fariborz Farsad
Hanieh Salehi
Contrast Media
707(1)
Key Points
701(1)
Introduction
701(1)
Cardiovascular Reactions
701(1)
Nephropathy
701(1)
Strategy for Preventing Radiocontrast-Induced Nephropathy
702(1)
Hypersensitivity Reactions to Radiographic Contrast Media
702(1)
Premedication Regimen in Immediate Hypersensitivity Reaction
703(1)
Antiplatelet Therapy in Percutaneous Coronary Intervention
703(1)
Key Points
703(1)
Introduction
703(1)
Aspirin Therapy
703(1)
Thienopyridine Therapy
703(1)
Ticlopidine
704(1)
Limitations of Use
704(1)
Clopidogrel
705(1)
Prasugrel
705(4)
Direct-Acting P2Y12 Inhibitors
706(1)
Ticagrelor
706(1)
Other Oral Antiplatelet Agents
706(1)
Parenteral Antiplatelet Agents
706(3)
Anticoagulant Therapy
709(1)
Key Points
709(1)
Introduction
709(1)
Anticoagulant Therapy: Classification
710(1)
Parenteral
710(1)
Unfractionated Heparin
710(1)
Low-Molecular-Weight Heparin
711(1)
Fondaparinux
711(1)
Bivalirudin
711(1)
Oral
711(6)
Vitamin K Antagonists
711(1)
Bridging Unfractionated Heparin, Low-Molecular-Weight Heparin, or Fondaparinux to Warfarin
712(1)
Most Common Warfarin Interactions
712(4)
New Oral Anticoagulants
716(1)
Oral Direct Thrombin Inhibitors
716(1)
Oral Direct Factor Xa Inhibitors
716(1)
Pregnancy and Venous Thromboembolism
717(1)
Anticoagulant Therapy to Prevent Embolization in Atrial Fibrillation
717(1)
Anticoagulation Therapy in Atrial Fibrillation
717(1)
Unfractionated Heparin in Atrial Fibrillation
718(1)
Dabigatran in AF
718(1)
Rivaroxaban in Atrial Fibrillation
719(1)
Apixaban in Atrial Fibrillation
719(1)
Edoxaban in Atrial Fibrillation
719(1)
Anticoagulation Before Cardioversion for Atrial Fibrillation Treatment
719(1)
Hemostasis Management of Cardiac Surgical Hemorrhage
719(1)
Key Points
719(1)
Introduction
719(2)
Fibrinogen
721(1)
Fresh-Frozen Plasma
721(1)
Prothrombin Complex Concentrates
722(1)
Drug Action Reversal and Vitamin K Antagonists for Urgent Surgery or Invasive Procedures
722(1)
Platelets
722(1)
Recommendation
722(1)
Antifibrinolytic Drugs
722(1)
Tranexamic Acid
723(1)
Epsilon Aminocaproic Acid
723(1)
Desmopressin
723(1)
Recombinant Factor Vila
723(1)
Activated Prothrombin Complex Concentrate
723(1)
Factor XIII
723(1)
Topical Sealants
724(1)
Mechanical
724(1)
Flowable
724(1)
Fibrin, Albumin, and Synthetic Sealants
724(1)
Active
724(1)
References
725(6)
40 COVID-19 Infection: A Novel Fatal Pandemic of the World in 2020
731(1)
Majid Maleki
Zeinab Norouzi
Alireza Maleki
Epidemiology
731(1)
Signs and Symptoms
731(1)
Treatment
732(1)
COVID-19 and Cardiovascular Disease
732(2)
Acknowledgment
734(1)
References
734(3)
41 Cardiovascular Disease in the COVID-19 Era: Myocardial Injury and Thrombosis
737(1)
Ahmad Amin
Parham Sadeghipour
Mitra Chitsazan
Introduction
737(1)
Key Points
738(1)
Diagnostic Approach to Patients With Acute Cardiac Injury
738(2)
Electrocardiogram
738(1)
Routine Laboratory Tests
738(1)
Chest X-ray
738(1)
Cardiac Troponins
738(1)
Natriuretic Peptides (BNP or NT-proBNP)
738(2)
Echocardiography
740(1)
Complications of Cardiac Injury in COVID-19
740(7)
Arrhythmias and Conduction Abnormalities
740(1)
Heart Failure
740(1)
Cardiogenic Shock
741(1)
Thrombosis in the COVID-19 Outbreak
741(1)
Venous Thromboembolism
741(1)
References
742(3)
42 Cardio-Oncology
745(1)
Azin Alizadehasl
Introduction
745(1)
Screening Before Anticancer Therapy
745(2)
Baseline Cardiovascular Risk Assessments (Pre-Anticancer Therapy)
745(1)
Baseline Measurement of Cardiac Biomarkers
745(1)
Baseline Electrocardiogram
745(1)
Baseline Assessment of Left Ventricular Ejection Fraction
746(1)
Primary Prevention Therapy
747(1)
Cardiovascular Therapeutics for Prevention
747(1)
Surveillance Strategies During Cancer Treatment
747(2)
Asymptomatic Patients and LVEF Decrease
748(1)
Asymptomatic Patients and LVEF Decrease Treated With Trastuzumab
748(1)
Asymptomatic Patients With Normal LVEF but Reduction in Average GLS
748(1)
Asymptomatic Patients and an Increase in Cardiac Troponin
749(1)
Clinical Cardiac Dysfunction
749(1)
Patients With a History of Mediastinal Chest Radiation
749(2)
Conclusion
751(1)
References
751(2)
43 Anesthesia and Sedation in Cardiac Patients
753(16)
Rasoul Azarfarin
Introduction
753(1)
Preoperative Anesthetic Assessment of Patients for Cardiac Surgery
754(1)
Risk Assessment of Patients for Cardiac Surgery
754(1)
Principles of Cardiac Anesthesia
755(2)
Cardiac Anesthesia Drugs and Techniques
757(2)
Inhalational Anesthetics
757(2)
Cardiopulmonary Bypass
759(1)
Noncardiac Surgery in Cardiac Patients
759(3)
Sedation and Analgesia for Cardiovascular Procedures
762(2)
Drugs Used for Procedural Sedation
764(1)
Monitoring During Procedural Sedation
765(1)
Sedation and Respiratory Care in Critically III Cardiac Care Unit Patients
765(1)
References
766(3)
44 Principles of Cardiovascular Surgery
769(16)
Saeid Hosseini
Alireza Alizadeh Ghavidel
Extracorporeal Circulation
769(1)
Deep Hypothermia and Circulatory Arrest
770(1)
Myocardial Protection
771(1)
Postoperative Care
771(1)
Insufficient Preload
771(1)
Cardiac Causes
772(1)
Increased Ventricular Afterload
772(1)
Approach to a Low-Output State
772(1)
Anticoagulation
773(1)
Mitral Valve Repair
773(1)
Mitral Valve Replacement
773(1)
Aortic Valve Replacement
774(1)
Pulmonary and Tricuspid Valves
774(1)
Heparin-lnduced Thrombocytopenia
774(6)
Mitral Valve Surgery
775(1)
Aortic Valve Surgery
775(3)
Tricuspid Valve Surgery
778(1)
Atrial Fibrillation Surgery
779(1)
Pericardium Surgery
779(1)
Coronary Artery Bypass Graft
780(1)
Off-Pump Coronary Artery Bypass Graft
780(1)
Minimally Invasive Cardiac Surgery
780(2)
Cardiac Surgery and COVID-19
782(1)
References
782(3)
Index 785