Preimplantation genetic testing (PGT) is now well established as a valuable treatment option for patients wishing to start or continue a family, for a range of indications from advanced maternal age to high risk of transmitting inherited disease. This text brings together contemporary thinking from international opinion leaders and will be an invaluable guide for practitioners in Reproductive Medicine wishing to keep pace with the latest developments and clinical data.
| Foreword |
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vii | |
| Editors |
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ix | |
| Contributors |
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xi | |
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1 Preimplantation Genetic Testing and Reproductive Genetics from a Physician's Perspective |
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1 | (10) |
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2 Genetic Counseling for Preimplantation Genetic Testing |
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11 | (14) |
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3 Preimplantation Genetic Testing for Aneuploidies: Where We Are and Where We're Going |
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25 | (24) |
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4 Preimplantation Genetic Testing for Structural Rearrangements |
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49 | (28) |
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5 Preimplantation Genetic Testing for Monogenic Disorders |
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77 | (10) |
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6 Novel Methods in Preimplantation Genetic Testing: Comprehensive Preimplantation Genetic Testing |
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87 | (10) |
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7 Time-Lapse Imaging and Preimplantation Genetic Testing |
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97 | (14) |
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8 Mosaicism Mechanisms in Preimplantation Embryos |
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111 | (16) |
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9 Transfer of Mosaic Embryos |
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127 | (12) |
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10 Noninvasive Methods of Preimplantation Genetic Testing for Aneuploidies |
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139 | (12) |
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Carmen Maria Garcia-Pascual |
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11 Preimplantation Genetic Testing in the Future |
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151 | (6) |
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| Index |
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157 | |
Darren K Griffin, PhD, DSc, FRSA, FRSB, FRCPath, is Professor of Genetics at the School of Biosciences, University of Kent, Canterbury, UK, President of the International Chromosome and Genome Society, and Director of the Centre for Interdisciplinary Studies of Reproduction. Gary Harton, PhD, is Global Director of Market Development PGD for Perkin-Elmer Inc., Waltham, MA, teacher at Eastern Virginia Medical School, Norfolk, VA, and at Bryant University, Smithfield, RI, USA: he has worked for over 20 years in both laboratory and clinical management in the IVF field and has served on a number of international committees including the ESHRE PGD Consortium and the UK Steering Committee for External Quality Assessment.
