This book provides readers with an anaesthesia-focused alternative to general physiology textbooks. The new edition has been reorganised with the trainee anaesthesist in mind, into shorter bite-sized chapters ideal for exam revision. The content includes the physiology of all major organ systems, with specific emphasis on the nervous, respiratory, and cardiovascular systems as well as special sections on pain, aging, specific environments and obesity. Alongside the learning objectives, reflection points and a handy summary of physiological equations and tables, there is greater emphasis on clinical application in this fourth edition, with applied physiology included in almost every section.
Preface to the first edition. Preface to the second edition. Preface to
the third edition. Preface to fourth edition. Acknowledgements. Authors.
Contributors. Basic Cell Physiology. Cell Components and Function. Physiology
of Excitable Cells. Neurotransmitters and Receptors, Ion Channels, G Proteins
and Second Messengers. Physiology of the Nervous System. Neuronal Function.
BloodBrain Barrier and Cerebrospinal Fluid (CSF). Cerebral Circulation.
Spinal Cord: Anatomical and Physiological Features. Sensory System. Motor
Function and Control: Descending Tracts. Autonomic Nervous System.
Consciousness, EEG, Sleep and Emotions. Muscle Physiology. Striated Muscles:
Skeletal and Cardiac Muscles. Muscle Spindles, Golgi Tendon Organs and Spinal
Reflexes. Smooth Muscle. Respiratory Physiology. Functions of the Respiratory
System. Mechanical Properties of the Lungs. Gas Exchange in the Lungs.
Carriage of Oxygen in Blood. Carbon Dioxide Carriage in Blood. Pulmonary
Circulation. Control of Ventilation. Applied Respiratory Physiology.
Cardiovascular Physiology. Functions of the Cardiovascular System. Electrical
Properties of the Heart. Mechanical Events of the Cardiac Cycle.
PressureVolume Loop of the Left Ventricle. Physical Factors Governing Blood
Flow Through Vessels. The Systemic Circulation. Microcirculation. Venous
Return and Vascular Function. Regulation of Arterial Blood Pressure.
Integrated Cardiovascular Responses. Gastrointestinal Physiology. Saliva,
Swallowing, and Lower Oesophageal Sphincter. Stomach: Gastric Secretions,
Motility, Digestion and Vomiting. The Small Intestine: Secretions, Digestion
and Motility. The Large Intestine. Liver Physiology. Functions of the Liver.
Liver Blood Flow. Liver Function Tests and Physiological Features of Liver
Failure. Renal Physiology. Functions of the Kidneys and Functional Anatomy.
Renal Blood Flow. Glomerular Filtration. Tubular Function. The Loop of Henle
and Production of Concentrated Urine: Counter-Current Mechanisms of the
Kidney. Overview of Renal Control of AcidBase Balance. Applied Physiology:
Renal Failure. AcidBase Physiology. Basic Concepts of AcidBase Physiology.
Compensatory Mechanisms in AcidBase Disorders. Clinical Aspects of AcidBase
Control. Anion Gap and Stewarts Strong Ion Difference. Physiology of Blood.
Cellular Components of Blood. Plasma: The Non-Cellular Components of Blood.
Haemostasis. Blood Transfusion. Physiology of the Immune System. Immune
System and Innate Immunity. Acquired Immunity. Cytokines. Hypersensitivity.
Endocrine Physiology. General Aspects of Endocrine Physiology. Pituitary
Gland. Hormones of the Pancreas. Thyroid Hormones and Calcium Metabolism.
Hormones of the Adrenal Gland. Erythropoietin, Atrial Natriuretic Peptide and
Sex Hormones. Metabolism, Nutrition, Exercise and Temperature Regulation.
Metabolism. Nutrition. Exercise Physiology. Temperature Regulation.
Physiology of Pain. Peripheral Mechanisms of Pain. Central Modulation of
Pain. Pain Sensitization. Physiology of Pregnancy, Placenta, Neonate, Ageing
and Obesity. Physiology of Pregnancy. Physiology of the Placenta. Physiology
of the Neonate. Physiology of Ageing. Physiology of Obesity. Special
Environments. Physiology Related to Special Environments. Further reading.
Index.
Peter Kam MBBS, MD, FRCA, FANCZA, FFARCSI, FHKCA (Hon)
Nuffield Professor of Anaesthetics, Sydney Medical School, University of Sydney Royal Prince Alfred Hospital Camperdown, Australia
Ian Power BSc (Hon), MD, FRCA, FFPMANZCA, FANZCA, FRCSEd, FRCP Edin, FFPFRCA
Emeritus Professor at the University of Edinburgh, Edinburgh, United Kingdom
