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Principles of Stem Cell Biology and Cancer: Future Applications and Therapeutics [Kõva köide]

  • Formaat: Hardback, 376 pages, kõrgus x laius x paksus: 252x175x22 mm, kaal: 880 g
  • Ilmumisaeg: 01-May-2015
  • Kirjastus: Wiley-Blackwell
  • ISBN-10: 1118670620
  • ISBN-13: 9781118670620
Teised raamatud teemal:
  • Formaat: Hardback, 376 pages, kõrgus x laius x paksus: 252x175x22 mm, kaal: 880 g
  • Ilmumisaeg: 01-May-2015
  • Kirjastus: Wiley-Blackwell
  • ISBN-10: 1118670620
  • ISBN-13: 9781118670620
Teised raamatud teemal:
PRINCIPLES OF STEM CELL BIOLOGY AND CANCER

Future Applications and Therapeutics

The field of cancer stem cells is expanding rapidly, with many groups focusing on isolating and identifying cancer stem cell populations. Although some progress has been made in developing efficient cancer therapies, targeting of cancer stem cells remains one of the important challenges facing the growing stem cell research community.

Principles of Stem Cell Biology and Cancer brings together original contributions from international experts in the field to present the very latest information linking stem cell biology and cancer. Divided into two parts, Principles of Stem Cell Biology and Cancer begins with a detailed introduction to stem cell biology, with a focus on the characterization of these cells, the progress that has been made in their identification and their future therapeutic applications. The second part focuses on cancer stem cells and their role in cancer development, progression and chemo-resistance. This part includes an overview of recent progress concerning therapies targeting cancer stem cells.

Principles of Stem Cell Biology and Cancer will prove an invaluable resource for basic and applied researchers and clinicians working on the development of new cancer treatments and therapies, providing a timely publication of high-quality reviews outlining the current progress and exciting future possibilities for stem cell research.

As the stem cell field has become a subject of extensive research in recent years with many groups focusing on isolating and identifying cancer stem cell populations, one of the important challenges facing the growing stem cell research community is developing efficient therapies targeting cancer stem cells. Regad, Sayers, Rees, and their international contributors aim to provide a detailed introduction to stem cell biology. Sixteen chapters are divided into two parts: stem cells; cancer stem cells. Part I focuses on the characterization of stem cells, the progress made toward their identification, and future therapeutic applications. Part II focuses on cancer stem cells and their role in cancer development, progression and chemoresistance, and presents an overview of recent progress in therapies targeting cancer stem cells. Annotation ©2015 Ringgold, Inc., Portland, OR (protoview.com)
List of Contributors vii
Preface xiii
Part I Stem Cells 1(100)
1 Isolation and Characterization of Human Embryonic Stem Cells and Future Applications in Tissue Engineering Therapies
3(24)
Christian Unger
James Hackland
David Preskey
Harry Moore
2 Epigenetics, Stem Cell Pluripotency and Differentiation
27(18)
Maria J. Barrero
3 Stem Cell Niche and Microenvironment
45(20)
Marcio Alvarez-Silva
4 Haematopoietic Stem Cells in Therapy
65(20)
Jos Domen
Jignesh Dalal
5 Isolation and Identification of Neural Stem/Progenitor Cells
85(16)
Loic P. Deleyrolle
Brent A. Reynolds
Part II Cancer Stem Cells 101(252)
6 The Role of Epithelial—Mesenchymal Transition in Cancer Metastasis
103(20)
Paul C. McDonald
Shoukat Dedhar
7 Regulation of Breast Cancer Stem Cells by Mesenchymal Stem Cells in the Metastatic Niche
123(22)
Fayaz Malik
Hasan Korkaya
Shawn G. Clouthier
Max S. Wicha
8 Isolation and Identification of Neural Cancer Stem/Progenitor Cells
145(24)
David Bakhshinyan
Maleeha A. Qazi
Neha Garg
Chitra Venugopal
Nicole McFarlane
Sheila K. Singh
9 Colon Stem Cells in Colorectal Cancer
169(24)
Varun V. Prabhu
Wafik S. El-Deity
Niklas Finnberg
10 Prostate Cancer and Prostate Cancer Stem Cells
193(20)
Magdalena E. Buczek
Jerome C. Edwards
Tarik Regad
11 Stem Cells and Pancreatic Cancer
213(18)
Audrey M. Hendley
Jennifer M. Bailey
12 NANOG in Cancer Development
231(22)
Bigang Liu
Dean G. Tang
13 Liver Cancer Stem Cells and Hepatocarcinogenesis
253(20)
Hirohisa Okabe
Hiromitsu Hayashi
Takatsugu Ishimoto
Kosuke Mima
Shigeki Nakagawa
Hideyuki Kuroki
Katsunori Imai
Hidetoshi Nitta
Daisuke Hashimoto
Akira Chikamoto
Takatoshi Ishiko
Toru Beppu
Hideo Baba
14 Basic Science of Liver Cancer Stem Cells and Hepatocarcinogenesis
273(32)
Katherine S. Koch
Hyam L. Leffert
15 Cancer Stem Cell Biomarkers
305(12)
Stefano Zapperi
Caterina A.M. La Porta
16 Interactomic Analysis of the Stem Cell Marker NANOG in a Prostate Cancer Setting
317(36)
Kiran Mall
Graham Ball
Index 353
Tarik Regad, The John van Geest Cancer Research Centre, Nottingham Trent University, Nottingham, UK

Thomas J. Sayers, Leidos Biomedical Research Inc., and the Cancer and Infl ammation Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA

Robert C. Rees, The John van Geest Cancer Research Centre, Nottingham Trent University, Nottingham, UK