Presents methodologies for the determination of equilibrium and kinetic constants in biochemical systems. Covers optical, chromatographic, electrophoretic, and other methods for studying biospecific interactions with soluble and membrane-bound proteins, and gives many applications and examples of appropriate methods for data evaluation. Specific topics include measurement of binding constants by frontal affinity chromotography, biospecific interaction analysis using integrated optics techniques, and receptor binding studies on lipid vesicles using the BIAcore. Annotation c. by Book News, Inc., Portland, Or.
