Muutke küpsiste eelistusi
  • Formaat: Paperback / softback, 256 pages, kõrgus x laius: 229x152 mm
  • Ilmumisaeg: 20-Oct-2019
  • Kirjastus: National Academies Press
  • ISBN-10: 0309486165
  • ISBN-13: 9780309486163
One of the pathways by which the scientific community confirms the validity of a new scientific discovery is by repeating the research that produced it. When a scientific effort fails to independently confirm the computations or results of a previous study, some fear that it may be a symptom of a lack of rigor in science, while others argue that such an observed inconsistency can be an important precursor to new discovery.



Concerns about reproducibility and replicability have been expressed in both scientific and popular media. As these concerns came to light, Congress requested that the National Academies of Sciences, Engineering, and Medicine conduct a study to assess the extent of issues related to reproducibility and replicability and to offer recommendations for improving rigor and transparency in scientific research.



Reproducibility and Replicability in Science defines reproducibility and replicability and examines the factors that may lead to non-reproducibility and non-replicability in research. Unlike the typical expectation of reproducibility between two computations, expectations about replicability are more nuanced, and in some cases a lack of replicability can aid the process of scientific discovery. This report provides recommendations to researchers, academic institutions, journals, and funders on steps they can take to improve reproducibility and replicability in science.

Table of Contents



Front Matter Executive Summary Summary 1 Introduction 2 Scientific Methods and Knowledge 3 Understanding Reproducibility and Replicability 4 Reproducibility 5 Replicability 6 Improving Reproducibility and Replicability 7 Confidence in Science References Appendix A: Biographical Sketches of Committee Members and Staff Appendix B: Agendas of Open Committee Meetings Appendix C: Recommendations Grouped by Stakeholder Appendix D: Using Bayes Analysis for Hypothesis Testing Appendix E: Conducting Replicable Surveys of Scientific Communities
Executive Summary 1(4)
Summary 5(16)
1 Introduction
21(6)
2 Scientific Methods And Knowledge
27(12)
What Is Science?
27(3)
Core Principles and Assumptions of Scientific Inquiry
30(4)
Nature Is Not Capricious
30(1)
Knowledge Grows Through Exploration of the Limits of Existing Rules and Mutually Reinforcing Evidence
31(1)
Science Is a Communal Enterprise
32(1)
Science Aims for Refined Degrees of Confidence, Rather Than Complete Certainty
32(1)
Scientific Knowledge Is Durable and Mutable
33(1)
Statistical Inference and Hypothesis Testing
34(5)
3 Understanding Reproducibility And Replicability
39(16)
The Evolving Practices of Science
39(3)
Defining Reproducibility and Replicability
42(4)
Precision of Measurement
46(5)
Variations in Methods Employed in a Study
51(1)
Rigor and Transparency
52(3)
4 Reproducibility
55(16)
Widespread Use of Computational Methods
55(4)
Nonpublic Data and Code
57(1)
Resources and Costs of Reproducibility
57(2)
Assessing Reproducibility
59(3)
The Extent of Non-Reproducibility
62(5)
Sources of Non-Reproducibility
67(4)
Inadequate Recordkeeping
67(2)
Nontransparent Reporting
69(1)
Obsolescence of Digital Artifacts
69(1)
Flawed Attempts to Reproduce Others' Research
70(1)
Barriers in the Culture of Research
70(1)
5 Replicability
71(34)
Assessing Replicability
72(3)
The Extent of Non-Replicability
75(10)
Assessments of Replicability
76(6)
Perspectives of Researchers Who Have Studied Replicability
82(1)
Surveys
82(1)
Retraction Trends
83(2)
Sources of Non-Replicability
85(20)
Non-Replicability That Is Potentially Helpful to Science
85(5)
Unhelpful Sources of Non-Replicability
90(1)
Publication Bias
91(4)
Misaligned Incentives
95(1)
Inappropriate Statistical Inference
96(2)
Poor Study Design
98(1)
Errors
98(1)
Incomplete Reporting of a Study
99(1)
Fraud and Misconduct
100(5)
6 Improving Reproducibility And Replicability
105(38)
Strengthening Research Practices: Broad Efforts and Responsibilities
105(5)
Education and Training
108(1)
Improving Knowledge and the Use of Statistical Significance Testing
109(1)
Efforts to Improve Reproducibility
110(9)
Recordkeeping
111(3)
Source Code and Data Version Control
114(1)
Scientific Workflow-Management Systems
114(2)
Tools for Reproduction of Results
116(2)
Publication Reproducibility Audits
118(1)
Overcoming Technological and Infrastructure Barriers to Reproducibility
119(8)
Archival Repositories and Open Data Platforms
119(2)
Code Hosting and Collaboration Platforms
121(1)
Digital Object Identifiers
122(1)
Obsolescence of Data and Code Storage
123(2)
Implementation Challenges
125(2)
Efforts to Improve Replicability
127(16)
Openness Guidelines
128(1)
Journal Requirements, Badges, and Awards
129(1)
Introducing Prepublication Checks for Errors and Anomalous Results
130(2)
Preregistration of Studies
132(2)
Encouraging the Publication of All Results
134(2)
Additional Journal Initiatives
136(1)
Research Funder Efforts to Encourage Replicability
137(3)
Developing Effective Funder Mandates
140(3)
7 Confidence In Science
143(46)
Research Synthesis
144(3)
Geoscience
147(2)
Genetics
149(1)
Psychology
150(3)
Social Science Research Using Big Data
153(2)
Public Perceptions of Reproducibility and Replicability
155(8)
Public Understanding of Science
155(2)
Public Trust in Science
157(1)
Media Coverage of Science
158(5)
References
163(26)
APPENDIXES
A Biographical Sketches of Committee Members and Staff
189(10)
B Agendas of Open Committee Meetings
199(10)
C Recommendations Grouped by Stakeholder
209(12)
D Using Bayes Analysis for Hypothesis Testing
221(10)
E Conducting Replicable Surveys of Scientific Communities
231